BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0178.0009.p (530 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value MA0777 [T] COG0642 Signal transduction histidine kinase 137 4e-32 aq_035_2 [T] COG2199 FOG: GGDEF domain 117 3e-26 PA0290_2 [T] COG2199 FOG: GGDEF domain 113 8e-25 BH2234 [T] COG3706 Response regulator containing a CheY-like rec... 113 8e-25 CC2462 [T] COG3706 Response regulator containing a CheY-like rec... 111 3e-24 >MA0777 [T] COG0642 Signal transduction histidine kinase Length = 567 Score = 137 bits (346), Expect = 4e-32, Method: Compositional matrix adjust. Identities = 96/352 (27%), Positives = 173/352 (49%), Gaps = 9/352 (2%) Query: 8 YIVIVSISGVLSALLALFAY--YKKTDFAGTRAFILSSLTSAIYTFGFALELSGSTMPEI 65 Y+ ++ SG++S LA+ AY + ++ F+LS L A+++ +A E+ + Sbjct: 3 YMGVLIFSGLISTSLAVRAYKVFNSRSLPFSKYFVLSMLCMALWSVNYAFEIGFVDLEYK 62 Query: 66 SFWIKVEYLGMPFIAPSSLLMIMYFVGLERLIRKGLVTALYAIPFISVLLVWTNDYHHLF 125 + + +YLG+ F+ + L + G+ R + L+ P I+VLL+ TN H L+ Sbjct: 63 YLFARFQYLGIAFVPVTWFLFAAEYTGVCRQFARKYEKPLFIFPVIAVLLMLTNSLHGLY 122 Query: 126 YQSMYFREGAPTPLIDVVMGPWYIVQGSLTFGCMLAGMCLILWQWNRMKRVYRRQLFTIF 185 ++ Y PL+ G ++ + +F +LAG+ Q+ R+ Y Q Sbjct: 123 FEGYYLDFSGGFPLLIFKHGAFFWIFYVYSFVLILAGVFFFFRQFVRLTTPYGTQAAIAL 182 Query: 186 IGQFLPALGAFLYLMDVTPYG-MDPVPVIMSITSTLYIWAILSRGMLTAAPIARENLFES 244 +P +G L++ DV P+ DP P +IT + W + L P+AR+++ ES Sbjct: 183 SAACIPVIGNILHVGDVGPFEFFDPTPFSFAITGLILFWGTIEHEFLNIIPVARQSVIES 242 Query: 245 MRDGVLVTDLSDMLVDYNRAAADMLQDLDASAIGKPLAQLFLPAGQDAVDYVMNSDPLIS 304 M DG +V DLS+ ++D N+AA ++ +G + LF ++ V+ + NS S Sbjct: 243 MNDGYIVVDLSNSIMDINKAALELAGKERKEVLGTNMNGLF----KEGVEVLGNSSEG-S 297 Query: 305 EERELGWNMNGETRYYQIRSSPVQKYGGHQVGRMIMLIDVTERTLLQEKLLQ 356 RE+ + ET+++ + SP+Q G+++M+ D+TE QE L Q Sbjct: 298 LGREISLQIGLETKFFSVSVSPLQTRDDED-GKLVMIHDITEIYRYQEALKQ 348 >aq_035_2 [T] COG2199 FOG: GGDEF domain Length = 251 Score = 117 bits (294), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 71/187 (37%), Positives = 102/187 (54%), Gaps = 7/187 (3%) Query: 338 MIMLIDVTERTLLQ---EKLL--QLATVDSLTGIYNRMHFMELSRGLLNEAALSLAPVSI 392 +I +I+ ++ L++ EK L ++A D LTG+YNR F E++ L +A SI Sbjct: 59 VIKMIETLKKILIETSKEKTLYERMALTDPLTGLYNRRVFTEMAEKELAKAKRYGYNFSI 118 Query: 393 ILLDIDFFKSINDRYGHHYGDMALQHIVTVCSSHLREGDIFGRYGGEEFVLCLPETSLKQ 452 +++DID FK IND YGH GD+ L+ I + ++R D+ R+GGEEF++ L T+L Sbjct: 119 LMIDIDNFKKINDTYGHDVGDLVLKKISEILKRNVRGADLVARFGGEEFIVMLSNTNLNG 178 Query: 453 AALLXXXXXXXXXXXXXXXXXG-PIHVTASFGVVEARGKNLSLEDLLSEADHALYTSKRN 511 A G + VT S GV RG SLE+L+ EAD ALY +KR Sbjct: 179 AVKKAEQLRRMIEQTPIELPNGEKLRVTVSIGVSTYRGHE-SLEELIKEADQALYEAKRK 237 Query: 512 GRNAVHV 518 G+N V V Sbjct: 238 GKNRVEV 244 >PA0290_2 [T] COG2199 FOG: GGDEF domain Length = 184 Score = 113 bits (283), Expect = 8e-25, Method: Compositional matrix adjust. Identities = 61/176 (34%), Positives = 91/176 (51%) Query: 343 DVTERTLLQEKLLQLATVDSLTGIYNRMHFMELSRGLLNEAALSLAPVSIILLDIDFFKS 402 D+T++ ++ +L +LAT D LT NR +F + + E P++ +LLD+D FK Sbjct: 8 DITDKKHMESELQRLATTDVLTQSSNRRYFFDSAEAAFKECRREGIPLAFLLLDVDDFKK 67 Query: 403 INDRYGHHYGDMALQHIVTVCSSHLREGDIFGRYGGEEFVLCLPETSLKQAALLXXXXXX 462 INDR+GH GD LQ I S+ LR GD+FGR GGEEF + LP + A + Sbjct: 68 INDRFGHQVGDQVLQRIAQSGSAALRRGDLFGRIGGEEFAVLLPGCDEQTARQIGERLQR 127 Query: 463 XXXXXXXXXXXGPIHVTASFGVVEARGKNLSLEDLLSEADHALYTSKRNGRNAVHV 518 +T S G+ + + L L S AD A+Y++KR G++ + V Sbjct: 128 EVQRLRFQEGEHSFGITVSQGLTVLQADDEGLGALYSRADAAMYSAKRQGKDCIVV 183 >BH2234 [T] COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain Length = 314 Score = 113 bits (282), Expect = 8e-25, Method: Compositional matrix adjust. Identities = 61/169 (36%), Positives = 91/169 (53%), Gaps = 1/169 (0%) Query: 352 EKLLQLATVDSLTGIYNRMHFMELSRGLLNEAALSLAPVSIILLDIDFFKSINDRYGHHY 411 +K+ +L+ VD LT + NR E R +N + ++ ++DIDFFK+IND YGH Sbjct: 146 QKVDRLSRVDFLTNLMNRRDMQEKIRAEINRSIRHGRSFTLAIVDIDFFKNINDTYGHDC 205 Query: 412 GDMALQHIVTVCSSHLREGDIFGRYGGEEFVLCLPETSLKQAALLXXXXXXXXXXXXXXX 471 GD L+H V+ + +R D R+GGEEF+L PET L++ Sbjct: 206 GDHVLKHFVSTLKNSVRSSDYVSRWGGEEFLLLFPETKLEEGKRACEKIRQKINESPVIY 265 Query: 472 XXGPIHVTASFGVVEARGKNLSLEDLLSEADHALYTSKRNGRNAVHVSS 520 I +TA+FG+ E R ++ +E+L+ AD ALY K+ G+N V V S Sbjct: 266 KGMSISITATFGISEYRP-SVRIEELIKAADDALYKGKKTGKNQVVVQS 313 >CC2462 [T] COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain Length = 454 Score = 111 bits (277), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 64/164 (39%), Positives = 89/164 (54%), Gaps = 2/164 (1%) Query: 355 LQLATVDSLTGIYNRMHFMELSRGLLNEAALSLAPVSIILLDIDFFKSINDRYGHHYGDM 414 L+LA D LTG++NR + L+ A L PVS +L+DIDFFK IND +GH GD Sbjct: 286 LELAVTDQLTGLHNRRYMTGQLDSLVKRATLGGDPVSALLIDIDFFKKINDTFGHDIGDE 345 Query: 415 ALQHIVTVCSSHLREGDIFGRYGGEEFVLCLPETSLKQAALLXXXXXXXXXXXXXXXXXG 474 L+ +S++R D+ RYGGEEFV+ +P+T+L A + G Sbjct: 346 VLREFALRLASNVRAIDLPCRYGGEEFVVIMPDTALADALRIAERIRMHVSGSPFTVAHG 405 Query: 475 P--IHVTASFGVVEARGKNLSLEDLLSEADHALYTSKRNGRNAV 516 ++VT S GV G+ + E LL AD +Y +K +GRNAV Sbjct: 406 REMLNVTISIGVSATAGEGDTPEALLKRADEGVYQAKASGRNAV 449 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.325 0.139 0.416 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 36,779,334 Number of extensions: 1557034 Number of successful extensions: 3687 Number of sequences better than 1.0e-05: 138 Number of HSP's gapped: 3532 Number of HSP's successfully gapped: 138 Length of query: 530 Length of database: 38,378,431 Length adjustment: 111 Effective length of query: 419 Effective length of database: 25,576,357 Effective search space: 10716493583 Effective search space used: 10716493583 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 118 (50.1 bits)