BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0176.0005.p (322 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value alr4380 [H] COG0113 Delta-aminolevulinic acid dehydratase 385 e-107 NMA0578_2 [K] COG2207 AraC-type DNA-binding domain-containing pr... 366 e-101 all4725 [H] COG0113 Delta-aminolevulinic acid dehydratase 339 3e-93 >alr4380 [H] COG0113 Delta-aminolevulinic acid dehydratase Length = 346 Score = 385 bits (988), Expect = e-107, Method: Compositional matrix adjust. Identities = 14/320 (4%), Positives = 49/320 (15%), Gaps = 4/320 (1%) Query: 1 LRGTAGIRGMVRETILNTLDFIQPIFVTYGTGVKNEISSMPGVYHFSLDTLKAEVDEIAA 60 + + + + Y + + +Y + E Sbjct: 10 SLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTETYV 69 Query: 61 LGIPAVLLFGIPETKDAVGSSAFAEDGIVQEATRLIKKWYPELLVVADTCLCEFTDHGHC 120 A + S + + + + + + Sbjct: 70 GNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYLDLY 129 Query: 121 GMXXXXXXXXXXXXXXINDASLDLLTRTAVSQARAGADIIAPSNMMDGFVHAIRAGLDEN 180 + + AVS + + Sbjct: 130 QVHWPQRPTNCF----GKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAFG 185 Query: 181 GFEHVPIMSYSVKYASAFYGPFREAADSAPQFGNRKTYQMDPANLREAIREADSDVLEGA 240 ++ + + + + G + Q + L + Sbjct: 186 VMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTGKY 245 Query: 241 DMLMVKPALAYLDVIRTIRDQFDLPLVAYNVSGEYSMVKAAALQGWIDEKAVVLEMLTGM 300 R R + A + + + Sbjct: 246 LNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMALAFVRRQPFVAST 305 Query: 301 KRAGADIIITYFAKDAARWL 320 + ++ Sbjct: 306 LLGATTMDQLKTNIESLHLE 325 >NMA0578_2 [K] COG2207 AraC-type DNA-binding domain-containing proteins Length = 324 Score = 366 bits (940), Expect = e-101, Method: Compositional matrix adjust. Identities = 182/316 (57%), Positives = 223/316 (70%), Gaps = 7/316 (2%) Query: 7 IRGMVRETILNTLDFIQPIFVTYGTGVKNEISSMPGVYHFSLDTLKAEVDEIAALGIPAV 66 IR ++RET L+ D + PIFV EISSMPG+Y+F L + E E A LGIPAV Sbjct: 15 IRDLIRETTLSVNDLVMPIFVNENIDSPVEISSMPGIYNFPLSEVAKEAKETADLGIPAV 74 Query: 67 LLFGIPETKDAVGSSAFAEDGIVQEATRLIK-KWYPELLVVADTCLCEFTDHGHCGMXXX 125 +LFG+P KDA GSS+ E IVQEA R IK + L+V+ D C+CE+T HGHCG+ Sbjct: 75 ILFGVPAFKDAEGSSSCGETDIVQEAVRRIKAELGDRLVVITDICMCEYTSHGHCGIIDF 134 Query: 126 XXXXXXXXXXXINDASLDLLTRTAVSQARAGADIIAPSNMMDGFVHAIRAGLDENGFEHV 185 +ND +L++L + AVS ARAGAD++APS MMDG V AIR LD +GFE+V Sbjct: 135 ETKEI------LNDPTLEVLGKIAVSHARAGADMVAPSGMMDGMVDAIRQALDFSGFENV 188 Query: 186 PIMSYSVKYASAFYGPFREAADSAPQFGNRKTYQMDPANLREAIREADSDVLEGADMLMV 245 PIMSY+ KY S FYGPFREAA+S FG+R TYQMDPAN EA+RE DV EGAD+LMV Sbjct: 189 PIMSYAAKYHSCFYGPFREAAESGYSFGDRSTYQMDPANSDEALREVTLDVAEGADILMV 248 Query: 246 KPALAYLDVIRTIRDQFDLPLVAYNVSGEYSMVKAAALQGWIDEKAVVLEMLTGMKRAGA 305 KPAL YLD++ ++ +FD+P AYNVSGEYSM+KAAA GW+DEK + E L +KRAGA Sbjct: 249 KPALPYLDIVYRVKTEFDMPTAAYNVSGEYSMIKAAAANGWLDEKKAIYESLISIKRAGA 308 Query: 306 DIIITYFAKDAARWLR 321 D IITYFAKDAAR L+ Sbjct: 309 DFIITYFAKDAARMLK 324 >all4725 [H] COG0113 Delta-aminolevulinic acid dehydratase Length = 346 Score = 339 bits (870), Expect = 3e-93, Method: Compositional matrix adjust. Identities = 23/313 (7%), Positives = 56/313 (17%), Gaps = 9/313 (2%) Query: 10 MVRETILNTLDFIQPIFVTYGTGVKNEISSMPGVYHFSLDTLKAEVDEIAALGIPAVLLF 69 L+ + + I A + Sbjct: 30 ADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTETYVGNWLAKHGSREKLIIASKVS 89 Query: 70 GI--PETKDAVGSSAFAEDGIVQEATRLIKKWYPELLVVADTCLCEFTDHGHCGMXXXXX 127 G K A I + +K+ + L + + + + Sbjct: 90 GPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYLDLYQVHWPQRPTNCFGKLGYSWT 149 Query: 128 XXXXXXXXXINDASLDLLTRTAVSQARAGADIIAPSNMMDGFVHAIRAGLDENGFEHVPI 187 SL RAG + F L + + Sbjct: 150 DS-------APAVSLLDTLDALAEYQRAGKIRYIGVSNETAFGVMRYLHLADKHDLPRIV 202 Query: 188 MSYSVKYASAFYGPFREAADSAPQFGNRKTYQMDPANLREAIREADSDVLEGADMLMVKP 247 + A S + Y + + L + Sbjct: 203 TIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTGKYLNGAKPAGARNTLFSRF 262 Query: 248 ALAYLDVIRTIRDQFDLPLVAYNVSGEYSMVKAAALQGWIDEKAVVLEMLTGMKRAGADI 307 + + + + + + Q ++ + + +K + Sbjct: 263 TRYSGEQTQKAVAAYVDIARRHGLDPAQMALAFVRRQPFVASTLLGATTMDQLKTNIESL 322 Query: 308 IITYFAKDAARWL 320 + A Sbjct: 323 HLELSEDVLAEIE 335 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.137 0.400 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 22,470,321 Number of extensions: 918613 Number of successful extensions: 7903 Number of sequences better than 1.0e-05: 3 Number of HSP's gapped: 7898 Number of HSP's successfully gapped: 3 Length of query: 322 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 216 Effective length of database: 26,153,027 Effective search space: 5649053832 Effective search space used: 5649053832 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 116 (49.3 bits)