BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0172.0004.p (364 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_yvhJ [K] COG1316 Transcriptional regulator 117 2e-26 BH3670 [K] COG1316 Transcriptional regulator 107 3e-23 BS_lytR [K] COG1316 Transcriptional regulator 102 1e-21 sll1872 [K] COG1316 Transcriptional regulator 100 7e-21 lin1025 [K] COG1316 Transcriptional regulator 99 1e-20 >BS_yvhJ [K] COG1316 Transcriptional regulator Length = 391 Score = 117 bits (294), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 79/271 (29%), Positives = 142/271 (52%), Gaps = 27/271 (9%) Query: 90 ERPITMLLLGT-DNRPKHPSNLTDVIMVAALNPTTQSATVVSLPRDTYVELSG---YKKT 145 ++P ++L +G D K +D ++V L+P ++ ++S+PRDT V+L+G KT Sbjct: 74 KKPFSILFMGIEDYATKGQKGRSDSLIVVTLDPKNKTMKMLSIPRDTRVQLAGDTTGSKT 133 Query: 146 KINEFYARFKSKEKTSGIPAEDEMKKMMGKYLDIDVDYATVLDFQGFRDVVDELGGVDVN 205 KIN Y++ +DE + + +L I +D +DF GF+DV++E+GG+DV+ Sbjct: 134 KINAAYSK----------GGKDETVETVENFLQIPIDKYVTVDFDGFKDVINEVGGIDVD 183 Query: 206 ISENMCYTDSVDGTD-INLTKGPARLDGDDALDYVRYRKSNCRPKTKASDDFDRNKRQNE 264 + + VD + I KG L+G++AL Y R RK + R DF RN RQ + Sbjct: 184 VPFDFDEKSDVDESKRIYFKKGEMHLNGEEALAYARMRKQDKRG------DFGRNDRQKQ 237 Query: 265 VLNSLVGQMQSLGGVLKIGKVLDAVDDNMKTDIENEQIKNIISAYWKISKENIEFKPVTG 324 +LN+L+ +M S + KI K+ + +N++T+I + + Y + + I+ +TG Sbjct: 238 ILNALIDRMSSASNIAKIDKIAEKASENVETNIRITEGLALQQIYSGFTSKKIDTLSITG 297 Query: 325 T--WRSP----YVYINDKELEAAKQSLHDRI 349 + + P Y + LE +++L + + Sbjct: 298 SDLYLGPNNTYYFEPDATNLEKVRKTLQEHL 328 >BH3670 [K] COG1316 Transcriptional regulator Length = 304 Score = 107 bits (267), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 83/275 (30%), Positives = 137/275 (49%), Gaps = 35/275 (12%) Query: 62 GYAGYLYWKFDHGSFGVDKPVQAGHSA----------AERPITMLLLGTDNRPKHPSNLT 111 GY YLY + + + +P+ G + A+ P ++L+ G D+R + + Sbjct: 21 GYGIYLYSSIQNTAGEMHEPLDRGDKSDKRDVAFDISAQDPFSILIAGVDSREDTHAGRS 80 Query: 112 DVIMVAALNPTTQSATVVSLPRDTYVELSGY-KKTKINEFYARFKSKEKTSGIPAEDEMK 170 D ++V +NP +S ++S+PRDT E+ G KIN YA F + T Sbjct: 81 DTLIVLTVNPKEESIKMLSIPRDTRTEIVGRGTDDKINHAYA-FGGAQMTI--------- 130 Query: 171 KMMGKYLDIDVDYATVLDFQGFRDVVDELGGVDVNISENMCYTDSVDGTDINLTKGPARL 230 + +LDI +D+ ++ GF +VD LGGV V EN + S +G +G L Sbjct: 131 DTVENFLDIPIDHYVSINMDGFTQLVDALGGVSV---EN-SFAFSQNGY--QFEEGEIFL 184 Query: 231 D-GDDALDYVRYRKSNCRPKTKASDDFDRNKRQNEVLNSLVGQMQSLGGVLKIGKVLDAV 289 + GD+AL Y R RK + R DF RN RQ +++ +++ Q + K G +LDAV Sbjct: 185 ETGDEALAYARMRKQDSRG------DFGRNDRQRQIVEAVIKQSAQFSSITKAGAILDAV 238 Query: 290 DDNMKTDIENEQIKNIISAYWKISKENIEFKPVTG 324 ++++TD++ + + + S Y +K NIE +TG Sbjct: 239 GESVRTDLQLDGMWELQSNYRGAAK-NIEQLEITG 272 >BS_lytR [K] COG1316 Transcriptional regulator Length = 306 Score = 102 bits (254), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 75/236 (31%), Positives = 123/236 (52%), Gaps = 27/236 (11%) Query: 92 PITMLLLGTDNRPKHPSNLTDVIMVAALNPTTQSATVVSLPRDTYVELSGYKKT--KINE 149 P ++L++G D R D ++ +NP T + +VS+PRDTY ++ G K T KIN Sbjct: 66 PFSVLIMGVDERDGDKGR-ADTLIYMTVNPKTNTTDMVSIPRDTYTKIIG-KGTMDKINH 123 Query: 150 FYARFKSKEKTSGIPAEDEMKKMMGKYLDIDVDYATVLDFQGFRDVVDELGGVDVNISEN 209 YA F + T + +LD+ VDY ++ + FRDVVD LGG+ VN + Sbjct: 124 SYA-FGGTQMTV---------DTVENFLDVPVDYFVKVNMESFRDVVDTLGGITVNSTFA 173 Query: 210 MCYTDSVDGTDINLTKGPARLDGDDALDYVRYRKSNCRPKTKASDDFDRNKRQNEVLNSL 269 Y DG + KG L+G +AL Y R RK + R DF R RQ +V+ + Sbjct: 174 FSY----DG--YSFGKGEITLNGKEALAYTRMRKEDPRG------DFGRQDRQRQVIQGI 221 Query: 270 VGQMQSLGGVLKIGKVLDAVDDNMKTDIENEQIKNIISAYWKISKENIEFKPVTGT 325 + + ++ + K G + V++N+KT++ + + +I S Y K ++++I+ + GT Sbjct: 222 INKGANISSITKFGDMFKVVENNVKTNLTFDNMWDIQSDY-KGARKHIKQHELKGT 276 >sll1872 [K] COG1316 Transcriptional regulator Length = 463 Score = 99.8 bits (247), Expect = 7e-21, Method: Compositional matrix adjust. Identities = 75/253 (29%), Positives = 122/253 (48%), Gaps = 36/253 (14%) Query: 91 RPITMLLLGT------DNRPKHPS-----------NLTDVIMVAALNPTTQSATVVSLPR 133 RPI +LLLGT + P P+ LTD +++ L+P +S V+S+PR Sbjct: 89 RPINVLLLGTKVLTSEEPDPSQPNPGYHALVNSVEGLTDTMVLIRLDPKEKSLVVLSIPR 148 Query: 134 DTYVELSGYKKTKINEFYARFKSKEKTSGIPAEDEMK--KMMGKYLDIDVDYATVLDFQG 191 DT VE+ GY AR ++ G PA M ++G D+ +D ++ Q Sbjct: 149 DTRVEIPGYSG-------ARKINQANALGGPALAAMTVTDLLG---DVPIDRYIRVNVQA 198 Query: 192 FRDVVDELGGVDVNISENMCYTDSVDGTDINLTKGPARLDGDDALDYVRYRKSNCRPKTK 251 ++D LGGVDV + +M Y D INL +G RLDG+ AL +R+R Sbjct: 199 VEKLIDALGGVDVYVPRDMKYQDDSQRLYINLKEGQQRLDGEKALQMLRFRYD------- 251 Query: 252 ASDDFDRNKRQNEVLNSLVGQMQSLGGVLKIGKVLDAVDDNMKTDIENEQIKNIISAYWK 311 A D R +RQ V+ ++V Q +L+I ++ + N+ T++ E++ I + Sbjct: 252 ALGDIGRIQRQQIVMRAVVEQALKPQTILRIPDIVKILQSNIDTNLNMEELVAIAGFSAQ 311 Query: 312 ISKENIEFKPVTG 324 I +E+++ + G Sbjct: 312 IPREDVKMLMLPG 324 >lin1025 [K] COG1316 Transcriptional regulator Length = 321 Score = 99.0 bits (245), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 74/243 (30%), Positives = 120/243 (49%), Gaps = 26/243 (10%) Query: 90 ERPITMLLLGTDNRPKHPSNLTDVIMVAALNPTTQSATVVSLPRDTYVELSGYKKTKINE 149 ++P ++LL+G+D RP + D I++A N + +VS+PRDT V+ KIN Sbjct: 70 KKPFSVLLMGSDARPGETNGRADTIILATANKQQNAVEMVSIPRDTKVDYGNGDIGKINA 129 Query: 150 FYARFKSKEKTSGIPAEDEMKKMMGKYLDIDVDYATVLDFQGFRDVVDELGGVDVNISEN 209 Y+ S + K M G + VDY ++ +GF+D+VD +GG+ V Sbjct: 130 SYSNGGPSGTVSAVE-----KLMPG----VPVDYFISINMEGFKDLVDAVGGITV----- 175 Query: 210 MCYTDSVDGTDIN--LTKGPARLDGDDALDYVRYRKSNCRPKTKASDDFDRNKRQNEVLN 267 Y D +D T++N KG L+G DAL YVR R + R DF R RQ +V+ Sbjct: 176 --YND-IDLTEVNSKFVKGNITLNGTDALQYVRIRHEDPR------GDFGRQDRQRDVII 226 Query: 268 SLVGQMQSLGGVLKIGKVLDAVDDNMKTDIENEQIKNIISAYWKISKENIEFKPVTGTWR 327 + ++ S GV ++ AV DN +T++ I ++ + Y + K N++ + + G Sbjct: 227 GIANKVISSSGVSNFESIMKAVGDNFQTNMTLTDITSMATNYSSVLK-NVDSQELKGEGE 285 Query: 328 SPY 330 Y Sbjct: 286 MIY 288 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.313 0.132 0.380 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 25,569,498 Number of extensions: 1105056 Number of successful extensions: 1459 Number of sequences better than 1.0e-05: 36 Number of HSP's gapped: 1406 Number of HSP's successfully gapped: 36 Length of query: 364 Length of database: 38,378,431 Length adjustment: 108 Effective length of query: 256 Effective length of database: 25,922,359 Effective search space: 6636123904 Effective search space used: 6636123904 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 116 (49.3 bits)