BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0168.0028.p (377 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH1718_2 [C] COG1413 FOG: HEAT repeat 177 3e-44 MA2540 [C] COG1413 FOG: HEAT repeat 58 2e-08 all3465_2 [C] COG1413 FOG: HEAT repeat 58 3e-08 MA4317 [C] COG1413 FOG: HEAT repeat 57 7e-08 MA3612 [T] COG5635 Predicted NTPase (NACHT family) 53 9e-07 >BH1718_2 [C] COG1413 FOG: HEAT repeat Length = 673 Score = 177 bits (449), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 7/147 (4%), Positives = 21/147 (14%) Query: 227 AALEDLAPTAELLPELRAALHDPKLHIRRLAVVYLGDIRTPEAMELLYEAMADSAPAVRR 286 L A + + + A + Sbjct: 1 MRLNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAA 60 Query: 287 TAGDTLSDIGDPAATPMMTASLTDKSKLVRWRAARFLYEVGTAEAQEALSLAVDDPEFEV 346 T + + + A E+ Sbjct: 61 REMKERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMKANFSLFDDTDQLALLKEL 120 Query: 347 GLQARMALERIASGEEAAGTVWQQMSE 373 + + + + W+ + Sbjct: 121 TEGLIEDDKVLLQQLISTISNWKNDLK 147 >MA2540 [C] COG1413 FOG: HEAT repeat Length = 673 Score = 58.2 bits (139), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 11/159 (6%), Positives = 28/159 (17%), Gaps = 10/159 (6%) Query: 213 LLRDLKDEDWRVRYAALEDLAPTAELLPELRAAL------HDPKLHIRRLAVVYLGDIRT 266 L+ +D ++ + A + H R + + G Sbjct: 258 LVLLSQDFPALKVIKLEQNYRSSGR--ILKAANILIANNPHVF--EKRLFSELGYGAELK 313 Query: 267 PEAMELLYEAMADSAPAVRRTAGDTLSDIGDPAATPMMTASLTDKSKLVRWRAARFLYEV 326 + + + D A K + + Sbjct: 314 VLSANNEEHEAERVTGELIAHHFVNKTQYKDYAILYRGNHQSRVFEKFLMQNRIPYKISG 373 Query: 327 GTAEAQEALSLAVDDPEFEVGLQARMALERIASGEEAAG 365 GT+ + + + Sbjct: 374 GTSFFSRPEIKDLLAYLRVLTNPDDDSAFLRIVNTPKRE 412 Score = 57.0 bits (136), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 6/112 (5%), Positives = 22/112 (19%) Query: 254 RRLAVVYLGDIRTPEAMELLYEAMADSAPAVRRTAGDTLSDIGDPAATPMMTASLTDKSK 313 A + T + L+ + T + + + Sbjct: 21 LAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAAREMKERVGQTLGRKEARGLM 80 Query: 314 LVRWRAARFLYEVGTAEAQEALSLAVDDPEFEVGLQARMALERIASGEEAAG 365 + + A + + + + E + ++ Sbjct: 81 ISTFHTLGLDIIKREYAALGMKANFSLFDDTDQLALLKELTEGLIEDDKVLL 132 Score = 51.2 bits (121), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 12/145 (8%), Positives = 24/145 (16%), Gaps = 2/145 (1%) Query: 225 RYAALEDLAPTA--ELLPELRAALHDPKLHIRRLAVVYLGDIRTPEAMELLYEAMADSAP 282 A ++ +R + + + L A Sbjct: 21 LAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAAREMKERVGQTLGRKEARGLM 80 Query: 283 AVRRTAGDTLSDIGDPAATPMMTASLTDKSKLVRWRAARFLYEVGTAEAQEALSLAVDDP 342 + AA M + + L Sbjct: 81 ISTFHTLGLDIIKREYAALGMKANFSLFDDTDQLALLKELTEGLIEDDKVLLQQLISTIS 140 Query: 343 EFEVGLQARMALERIASGEEAAGTV 367 ++ L+ A GE Sbjct: 141 NWKNDLKTPSQAAASAIGERDRIFA 165 >all3465_2 [C] COG1413 FOG: HEAT repeat Length = 673 Score = 57.8 bits (138), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 9/148 (6%), Positives = 20/148 (13%), Gaps = 2/148 (1%) Query: 212 ELLRDLKDEDWRVRYAALEDLAPT-AEL-LPELRAALHDPKLHIRRLAVVYLGDIRTPEA 269 L P E L + K+ + Sbjct: 273 LEQNYRSSGRILKAANILIANNPHVFEKRLFSELGYGAELKVLSANNEEHEAERVTGELI 332 Query: 270 MELLYEAMADSAPAVRRTAGDTLSDIGDPAATPMMTASLTDKSKLVRWRAARFLYEVGTA 329 A+ + ++ + + L Sbjct: 333 AHHFVNKTQYKDYAILYRGNHQSRVFEKFLMQNRIPYKISGGTSFFSRPEIKDLLAYLRV 392 Query: 330 EAQEALSLAVDDPEFEVGLQARMALERI 357 A + A + Sbjct: 393 LTNPDDDSAFLRIVNTPKREIGPATLKK 420 Score = 55.5 bits (132), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 6/150 (4%), Positives = 24/150 (16%), Gaps = 2/150 (1%) Query: 212 ELLRDLKDEDWRVRYAALEDLAPT-AEL-LPELRAALHDPKLHIRRLAVVYLGDIRTPEA 269 + + + + A + + ++ ++ + Sbjct: 242 DDDQSIYSWRGARPQNLVLLSQDFPALKVIKLEQNYRSSGRILKAANILIANNPHVFEKR 301 Query: 270 MELLYEAMADSAPAVRRTAGDTLSDIGDPAATPMMTASLTDKSKLVRWRAARFLYEVGTA 329 + A+ + K + +R Sbjct: 302 LFSELGYGAELKVLSANNEEHEAERVTGELIAHHFVNKTQYKDYAILYRGNHQSRVFEKF 361 Query: 330 EAQEALSLAVDDPEFEVGLQARMALERIAS 359 Q + + L Sbjct: 362 LMQNRIPYKISGGTSFFSRPEIKDLLAYLR 391 Score = 52.0 bits (123), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 7/150 (4%), Positives = 30/150 (20%), Gaps = 2/150 (1%) Query: 212 ELLRDLKDEDWRVRYAALEDLAPT-AEL-LPELRAALHDPKLHIRRLAVVYLGDIRTPEA 269 L+ + +D + + + + +++ + + V+ D + Sbjct: 211 LLVDEYQDTNTSQYELVKLLVGSRARFTVVGDDDQSIYSWRGARPQNLVLLSQDFPALKV 270 Query: 270 MELLYEAMADSAPAVRRTAGDTLSDIGDPAATPMMTASLTDKSKLVRWRAARFLYEVGTA 329 ++L + + + L V Sbjct: 271 IKLEQNYRSSGRILKAANILIANNPHVFEKRLFSELGYGAELKVLSANNEEHEAERVTGE 330 Query: 330 EAQEALSLAVDDPEFEVGLQARMALERIAS 359 ++ + + Sbjct: 331 LIAHHFVNKTQYKDYAILYRGNHQSRVFEK 360 >MA4317 [C] COG1413 FOG: HEAT repeat Length = 673 Score = 56.6 bits (135), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 8/143 (5%), Positives = 13/143 (9%), Gaps = 5/143 (3%) Query: 184 RLDSLVQQAIAHGAGGEFVEQREKKDQAELLRDLKDEDWRVRYA---ALEDLAPTAELLP 240 S V + + + Sbjct: 352 NHQSRVFEKFLMQNRI-PYKISGGTSFFSRPEIKDLLAYLRVLTNPDDDSAFLRIVNTPK 410 Query: 241 ELRAALHDPKLHIRRLAVVYLGDIRTPEAMELLYEAMADSAPAVRRTAGDTLSDIGDPAA 300 K M L A+ R Sbjct: 411 REIG-PATLKKLGEWAMTRNKSMFTASFDMGLSQTLSGRGYEALTRFTHWLAEIQRLAER 469 Query: 301 TPMMTASLTDKSKLVRWRAARFL 323 P+ Sbjct: 470 EPIAAVRDLIHGMDYESWLYETS 492 >MA3612 [T] COG5635 Predicted NTPase (NACHT family) Length = 1157 Score = 52.8 bits (125), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 63/221 (28%), Positives = 99/221 (44%), Gaps = 17/221 (7%) Query: 148 VLIKERKLTDYGVRYGEPETIAREVEQE----LEAAYPQERLDSLVQQAIAHGAGGEFVE 203 VLI D VR+G + R Q+ L A+ +E D LV+ A G + Sbjct: 638 VLISALGDKDDFVRFGAMGALGRATPQKAATPLIKAFKEE--DKLVRWGAAEALG----Q 691 Query: 204 QREKKDQAELLRDLKDEDWRVRYAALEDLAPT-AELLPE-LRAALHDPKLHIRRLAVVYL 261 R +K + L+DED VR+ A++ L ++ P+ L D +RR A L Sbjct: 692 MRSEKAVEPFMDALQDEDEFVRWIAIKALGKIKSDQTPDTFTCTLGDKSHFVRREAAKTL 751 Query: 262 GDIRTPEAMELLYEAMADSAPAVRRTAGDTLSD-----IGDPAATPMMTASLTDKSKLVR 316 G + + + ++LL A++D VR+ A + L + G A + L+D+S LVR Sbjct: 752 GMLGSEKTLDLLVSALSDENEFVRKAAAEALGERGPEIAGSNTAVGALVKRLSDESHLVR 811 Query: 317 WRAARFLYEVGTAEAQEALSLAVDDPEFEVGLQARMALERI 357 AA+ L + EA L L + D V +A AL ++ Sbjct: 812 LEAAKALGMTRSREAVTPLLLVLGDENRFVRKEAAKALGKL 852 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.316 0.130 0.368 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 27,506,008 Number of extensions: 1144239 Number of successful extensions: 2561 Number of sequences better than 1.0e-05: 9 Number of HSP's gapped: 2540 Number of HSP's successfully gapped: 22 Length of query: 377 Length of database: 38,378,431 Length adjustment: 108 Effective length of query: 269 Effective length of database: 25,922,359 Effective search space: 6973114571 Effective search space used: 6973114571 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 117 (49.7 bits)