BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0168.0016.p (1222 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll2385_3 [T] COG0642 Signal transduction histidine kinase 285 3e-76 mll2385_4 [T] COG0784 FOG: CheY-like receiver 226 2e-58 all0542_3 [T] COG0642 Signal transduction histidine kinase 169 2e-41 SMb20356_1 [T] COG0642 Signal transduction histidine kinase 164 7e-40 MA2013_2 [T] COG0642 Signal transduction histidine kinase 156 2e-37 >mll2385_3 [T] COG0642 Signal transduction histidine kinase Length = 354 Score = 285 bits (729), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 163/348 (46%), Positives = 215/348 (61%), Gaps = 32/348 (9%) Query: 495 NTELVAKTRALEDQVQEVEEKKDEIEQARRQLEKQAMQLAVTSKYKSEFLANMSHELRTP 554 N EL K + LE++ ++VE K EIE ARR LE++A QLA+TSKYKSEFLANMSHELRTP Sbjct: 30 NEELQEKAQLLENEKKQVENKNLEIEMARRALEEKAEQLALTSKYKSEFLANMSHELRTP 89 Query: 555 XXXXXXXXXXXTENKEGNLTEKQVEFAHTIYMSGADLLKMIDEILDLSKVDAGKMELNYE 614 N++GNL EKQVEFA TI +G DLL +I++ILDLSK+++G + ++ Sbjct: 90 LNSLLILSNLLAANQQGNLNEKQVEFARTINSAGTDLLSLINDILDLSKIESGTVSIDIN 149 Query: 615 EIPLTDLKTFVKQNFAPQAAKKGLSLRLLFDEPLPDAIYTDSHRLKQILRNLLSNAFKFT 674 ++P+ L+ + + F AA KGL + D LP+ + TD RL+QI+ NLLSNAFKFT Sbjct: 150 DMPVAHLRQHMDRTFRQLAADKGLGFTINVDPELPETVRTDEKRLQQIVLNLLSNAFKFT 209 Query: 675 SEGFV--EFSVSAADKEQLPAFLPHEYNYIALSVKDSGIGIPADKTDIVFEAFQQVDGTT 732 S G V +F V + A P +A++V D+GIGIP DK ++FEAFQQ DGTT Sbjct: 210 SAGEVRLDFRVEKTGRRN-GARQPK--RALAIAVTDTGIGIPEDKQKLIFEAFQQADGTT 266 Query: 733 SRKYGGTGLGLSISRELARLMGGAIGLDSREGQGSIFTLYLPVKG-------QYSLLPGX 785 SRKYGGTGLGLSISRE+ARL+GG + ++S G+GS FTL +P+ G Q LLP Sbjct: 267 SRKYGGTGLGLSISREIARLLGGELRVESTPGKGSTFTLMIPLDGPRVAMTTQPELLPA- 325 Query: 786 XXXXXXXXXXXXPDYDSGRGEDYTQEASPAPLESVVVEDDREDLSSKD 833 E SP+ L S + DDR+ +S +D Sbjct: 326 -------------------AEAIGTAGSPSGLPSAELMDDRDAISPED 354 >mll2385_4 [T] COG0784 FOG: CheY-like receiver Length = 398 Score = 226 bits (575), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 140/389 (35%), Positives = 213/389 (54%), Gaps = 11/389 (2%) Query: 834 KVLLIIEDDEKFARILLDMARSRGFKGLVALQGDTGLNMATTYLPDAIILDIQLPVMDGW 893 +V+LI+EDD F +LL +ARS G KG+++ G L +A +PDAI LD+ L +DGW Sbjct: 1 RVVLIVEDDPTFGGLLLGLARSAGLKGVLSTAGSGTLALARKLVPDAITLDLGLSDIDGW 60 Query: 894 AILRELKGSSQTRHIPVHVISVNDEVKQGLMMGAMAYLRKPSTREALERAFSQIESYTAS 953 + L+ +T IPVHVIS +++ GA + KP + + L F I S Sbjct: 61 VLFDLLRHDPKTSGIPVHVISGAEDIDDLASKGASSISTKPVSSDELMNVFQDIHSRKLR 120 Query: 954 TLKHLLVVEDDDIQRRSIMELIGHDDVAITAVSTGHEALAELRKQKYDCXXXXXXXXXXT 1013 + +LV + D +R S++E I ++TA+ ++ YD Sbjct: 121 IQRRVLVADPDPERRLSLVEAIRDGVTSVTAIGRVAANADDIELASYDAVVLGFGRSAKD 180 Query: 1014 GFELLDQIRDDEELNDLPIIIYTGKDLDNKEETRLRKYAESIIIKDVRSPERLLDETTLF 1073 + LD++ + LP +++ + E+ A + DV E L Sbjct: 181 NAQALDELAS-QSAGALPPLLFFAPHSEAIEQVLTLNPAWA----DVPRAENF---AQLA 232 Query: 1074 LHRVEANLPEDKRKILQKLHNKEELFD--GKKILLVDDDIRNVFALSSVLEGYHMEVKFA 1131 LH + A LP R+ + + + + G K+L+VDDDIRN+++L+SVLE Y +EV A Sbjct: 233 LH-ISATLPGGARQDSGRETGEADKSNLAGAKVLIVDDDIRNIYSLTSVLETYDIEVMHA 291 Query: 1132 ENGREALDMLVEQEDFDLVLMDMMMPEMDGYEAMRRIRQMPQYQKLPIIALTAKAMKEDR 1191 E GRE + +L + D D L+D+MMPEMDGYE MR+IR P +P+I++TAKAMK DR Sbjct: 292 ERGREGIALLEQVPDVDAALIDIMMPEMDGYETMRQIRNTPAIAHIPLISVTAKAMKGDR 351 Query: 1192 AKCIEAGASDYMKKPISTEQLLSLMRVWL 1220 KC++AGASDY+ KP+ + LL+L+RVW+ Sbjct: 352 QKCLDAGASDYIAKPVDLDLLLALLRVWI 380 >all0542_3 [T] COG0642 Signal transduction histidine kinase Length = 227 Score = 169 bits (428), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 102/235 (43%), Positives = 138/235 (58%), Gaps = 13/235 (5%) Query: 540 KSEFLANMSHELRTPXXXXXXXXXXXTENKEGNLTEKQVEFAHTIYMSGADLLKMIDEIL 599 KSEFLA MSHELRTP + G+L EKQ E+ + IY SG LL +I++IL Sbjct: 2 KSEFLATMSHELRTPLNAIMGLSQLLQQEIVGSLNEKQQEYINCIYSSGEHLLALINDIL 61 Query: 600 DLSKVDAGKMELNYEEIPLTDLKTFVKQNFAPQAAKKGLSLRLLFDEPLPDAIYTDSHRL 659 DLSKV+AGK EL + + D+ V +A KGL L D P + D R+ Sbjct: 62 DLSKVEAGKEELFLIPLLVIDVCNDVLLTVRDRAISKGLKLTQEID-PEANICIADDRRI 120 Query: 660 KQILRNLLSNAFKFTSEGFVEFSVSAADKEQLPAFLPHEYNYIALSVKDSGIGIPADKTD 719 KQ+L NLL+NA KFTS G V V +P N+I + D+GIGI +++ Sbjct: 121 KQMLLNLLTNAIKFTSVGEVSLIVKR---------VPEGINFI---ISDTGIGIDSNQFP 168 Query: 720 IVFEAFQQVDGTTSRKYGGTGLGLSISRELARLMGGAIGLDSREGQGSIFTLYLP 774 ++FE F+Q+D +R+Y GTGLGL+++R+LARL GG + + S G GS FTL+LP Sbjct: 169 LLFEPFKQLDSRLNRQYEGTGLGLALTRKLARLHGGDVTVTSTVGVGSQFTLFLP 223 >SMb20356_1 [T] COG0642 Signal transduction histidine kinase Length = 667 Score = 164 bits (416), Expect = 7e-40, Method: Compositional matrix adjust. Identities = 99/277 (35%), Positives = 157/277 (56%), Gaps = 16/277 (5%) Query: 502 TRALEDQVQEVEEKKDEIEQARRQLEKQAMQLAVTSKYKSEFLANMSHELRTPXXXXXXX 561 T A+ + ++++++ E+E+A+ E ++ KS FLA+MSHELRTP Sbjct: 390 TVAVYTDITQLKQRQVELERAKSHAES-------ANEAKSRFLASMSHELRTPLNAIIGY 442 Query: 562 XXXXTENKEGNLTEKQVEFAHTIYMSGADLLKMIDEILDLSKVDAGKMELNYEEIPLTDL 621 E + E+ V I +G LL +I++ILDLSK++A KME+ E + DL Sbjct: 443 SEMLIEEARDHEDEELVPDLDKIASAGRHLLSLINDILDLSKIEANKMEVFLETFSVADL 502 Query: 622 KTFVKQNFAPQAAKKGLSLRLLFDEPLPDAIYTDSHRLKQILRNLLSNAFKFTSEGFVEF 681 V AP A+ G F+ L + +++D +L+Q L NLLSNA KFT+ G V Sbjct: 503 LRDVAATVAPLMARNGNEFTQDFEADLGE-MHSDQTKLRQNLFNLLSNAAKFTNGGRVTL 561 Query: 682 SVSAADKEQLPAFLPHEYNYIALSVKDSGIGIPADKTDIVFEAFQQVDGTTSRKYGGTGL 741 V +EQ P + +++ V D+GIG+ ++ + +F AF Q D +T+R YGGTGL Sbjct: 562 RVR---REQRP-----DRDWLVFQVTDTGIGMSPEQQERLFNAFTQADASTTRNYGGTGL 613 Query: 742 GLSISRELARLMGGAIGLDSREGQGSIFTLYLPVKGQ 778 GLSI+R R++GG + ++S G+GS+FT+ +P + + Sbjct: 614 GLSITRSFCRMIGGVVTVESEVGKGSVFTMEVPAQCE 650 >MA2013_2 [T] COG0642 Signal transduction histidine kinase Length = 296 Score = 156 bits (395), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 93/252 (36%), Positives = 133/252 (52%), Gaps = 23/252 (9%) Query: 537 SKYKSEFLANMSHELRTPXXXXXXXXXXXTENKEGNLTEKQVEFAHTIYMSGADLLKMID 596 +K K +FLANMSHE+RTP E +LT++Q E+ + S LL +ID Sbjct: 18 NKAKGDFLANMSHEIRTPMNAVLGMLEMLLET---SLTDEQREYLQLAHASAESLLSIID 74 Query: 597 EILDLSKVDAGKMELNYEEIPLTDLKTFVKQNFAPQAAKKGLSLRLLFDEPLPDAIYTDS 656 ++LD SK++ K+EL L L + + + +A KGL L ++ LP D Sbjct: 75 DVLDFSKIEQNKLELEQISFELESLISHIINLLSGKAGSKGLKLAFHIEKDLPSTFIGDP 134 Query: 657 HRLKQILRNLLSNAFKFTSEGFVEFSVSAADKEQLPAFLPHEYNY------------IAL 704 RLKQ+L N+L NA KFT +G + SV ++P E N + Sbjct: 135 VRLKQVLFNILGNAIKFTKKGEIALSVE--------VYMPSERNSGLSNSDFPEEVALLF 186 Query: 705 SVKDSGIGIPADKTDIVFEAFQQVDGTTSRKYGGTGLGLSISRELARLMGGAIGLDSREG 764 VKD+GIGIP +K +F+ F Q D + +R+YGGTGLGL+IS +L LM G I ++S G Sbjct: 187 KVKDTGIGIPPEKLSQIFDPFIQADASVTREYGGTGLGLAISSQLVELMEGRIWVESEVG 246 Query: 765 QGSIFTLYLPVK 776 +G F + VK Sbjct: 247 KGCTFYFTVRVK 258 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.316 0.133 0.362 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 77,837,263 Number of extensions: 3157432 Number of successful extensions: 22452 Number of sequences better than 1.0e-05: 626 Number of HSP's gapped: 21999 Number of HSP's successfully gapped: 741 Length of query: 1222 Length of database: 38,378,431 Length adjustment: 118 Effective length of query: 1104 Effective length of database: 24,769,019 Effective search space: 27344996976 Effective search space used: 27344996976 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 122 (51.6 bits)