BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0168.0014.p (556 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value MA2013_2 [T] COG0642 Signal transduction histidine kinase 232 1e-60 ZbarA_1 [T] COG0642 Signal transduction histidine kinase 211 3e-54 barA_1 [T] COG0642 Signal transduction histidine kinase 211 3e-54 ZbarA_1 [T] COG0642 Signal transduction histidine kinase 211 3e-54 PA0928_1 [T] COG0642 Signal transduction histidine kinase 207 5e-53 >MA2013_2 [T] COG0642 Signal transduction histidine kinase Length = 296 Score = 232 bits (592), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 120/253 (47%), Positives = 170/253 (67%), Gaps = 15/253 (5%) Query: 171 EFLAMMSHEIRTPMNGVVGMIDLLMETELAPEQKEYTEIIRKSADTLITVINDILDFTKM 230 +FLA MSHEIRTPMN V+GM+++L+ET L EQ+EY ++ SA++L+++I+D+LDF+K+ Sbjct: 23 DFLANMSHEIRTPMNAVLGMLEMLLETSLTDEQREYLQLAHASAESLLSIIDDVLDFSKI 82 Query: 231 ESGKMEMEEQLFELQTTIQEVFSLFSAEAGKKNLELAYFIDQKLPRLIYGDMARLRQVLI 290 E K+E+E+ FEL++ I + +L S +AG K L+LA+ I++ LP GD RL+QVL Sbjct: 83 EQNKLELEQISFELESLISHIINLLSGKAGSKGLKLAFHIEKDLPSTFIGDPVRLKQVLF 142 Query: 291 NLVANAVKFTNQGGVYL-VASSVPSEDN----------KLTVEFTIKDTGIGISPEKCDR 339 N++ NA+KFT +G + L V +PSE N ++ + F +KDTGIGI PEK + Sbjct: 143 NILGNAIKFTKKGEIALSVEVYMPSERNSGLSNSDFPEEVALLFKVKDTGIGIPPEKLSQ 202 Query: 340 LFQPFSQLDSSMTRKYGGTGLGLAICKSLVGMMGGEIRVESMEEKGATFVFTIKTAVPED 399 +F PF Q D+S+TR+YGGTGLGLAI LV +M G I VES KG TF FT++ E Sbjct: 203 IFDPFIQADASVTREYGGTGLGLAISSQLVELMEGRIWVESEVGKGCTFYFTVRVKRGES 262 Query: 400 E----LGKNLQEE 408 G N+ EE Sbjct: 263 SENYGQGNNIPEE 275 >ZbarA_1 [T] COG0642 Signal transduction histidine kinase Length = 525 Score = 211 bits (537), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 100/224 (44%), Positives = 147/224 (65%) Query: 170 TEFLAMMSHEIRTPMNGVVGMIDLLMETELAPEQKEYTEIIRKSADTLITVINDILDFTK 229 +EFLA MSHE+RTP+NGV+G L ++TEL P Q+++ I +SA+ L+ +IND+LDF+K Sbjct: 294 SEFLANMSHELRTPLNGVIGFTRLTLKTELTPTQRDHLNTIERSANNLLAIINDVLDFSK 353 Query: 230 MESGKMEMEEQLFELQTTIQEVFSLFSAEAGKKNLELAYFIDQKLPRLIYGDMARLRQVL 289 +E+GK+ +E F L++T+ EV +L + + K LEL I +P + GD RL+Q++ Sbjct: 354 LEAGKLILESIPFPLRSTLDEVVTLLAHSSHDKGLELTLNIKSDVPDNVIGDPLRLQQII 413 Query: 290 INLVANAVKFTNQGGVYLVASSVPSEDNKLTVEFTIKDTGIGISPEKCDRLFQPFSQLDS 349 NLV NA+KFT G + ++ + K+ +E I+DTGIGI RLFQ F Q D+ Sbjct: 414 TNLVGNAIKFTENGNIDILVEKRALSNTKVQIEVQIRDTGIGIPERDQSRLFQAFRQADA 473 Query: 350 SMTRKYGGTGLGLAICKSLVGMMGGEIRVESMEEKGATFVFTIK 393 S++R++GGTGLGL I + LV MGG+I S +G+TF F I Sbjct: 474 SISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHIN 517 >barA_1 [T] COG0642 Signal transduction histidine kinase Length = 525 Score = 211 bits (537), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 100/224 (44%), Positives = 147/224 (65%) Query: 170 TEFLAMMSHEIRTPMNGVVGMIDLLMETELAPEQKEYTEIIRKSADTLITVINDILDFTK 229 +EFLA MSHE+RTP+NGV+G L ++TEL P Q+++ I +SA+ L+ +IND+LDF+K Sbjct: 294 SEFLANMSHELRTPLNGVIGFTRLTLKTELTPTQRDHLNTIERSANNLLAIINDVLDFSK 353 Query: 230 MESGKMEMEEQLFELQTTIQEVFSLFSAEAGKKNLELAYFIDQKLPRLIYGDMARLRQVL 289 +E+GK+ +E F L++T+ EV +L + + K LEL I +P + GD RL+Q++ Sbjct: 354 LEAGKLILESIPFPLRSTLDEVVTLLAHSSHDKGLELTLNIKSDVPDNVIGDPLRLQQII 413 Query: 290 INLVANAVKFTNQGGVYLVASSVPSEDNKLTVEFTIKDTGIGISPEKCDRLFQPFSQLDS 349 NLV NA+KFT G + ++ + K+ +E I+DTGIGI RLFQ F Q D+ Sbjct: 414 TNLVGNAIKFTENGNIDILVEKRALSNTKVQIEVQIRDTGIGIPERDQSRLFQAFRQADA 473 Query: 350 SMTRKYGGTGLGLAICKSLVGMMGGEIRVESMEEKGATFVFTIK 393 S++R++GGTGLGL I + LV MGG+I S +G+TF F I Sbjct: 474 SISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHIN 517 Score = 211 bits (537), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 100/224 (44%), Positives = 147/224 (65%) Query: 170 TEFLAMMSHEIRTPMNGVVGMIDLLMETELAPEQKEYTEIIRKSADTLITVINDILDFTK 229 +EFLA MSHE+RTP+NGV+G L ++TEL P Q+++ I +SA+ L+ +IND+LDF+K Sbjct: 294 SEFLANMSHELRTPLNGVIGFTRLTLKTELTPTQRDHLNTIERSANNLLAIINDVLDFSK 353 Query: 230 MESGKMEMEEQLFELQTTIQEVFSLFSAEAGKKNLELAYFIDQKLPRLIYGDMARLRQVL 289 +E+GK+ +E F L++T+ EV +L + + K LEL I +P + GD RL+Q++ Sbjct: 354 LEAGKLILESIPFPLRSTLDEVVTLLAHSSHDKGLELTLNIKSDVPDNVIGDPLRLQQII 413 Query: 290 INLVANAVKFTNQGGVYLVASSVPSEDNKLTVEFTIKDTGIGISPEKCDRLFQPFSQLDS 349 NLV NA+KFT G + ++ + K+ +E I+DTGIGI RLFQ F Q D+ Sbjct: 414 TNLVGNAIKFTENGNIDILVEKRALSNTKVQIEVQIRDTGIGIPERDQSRLFQAFRQADA 473 Query: 350 SMTRKYGGTGLGLAICKSLVGMMGGEIRVESMEEKGATFVFTIK 393 S++R++GGTGLGL I + LV MGG+I S +G+TF F I Sbjct: 474 SISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHIN 517 >PA0928_1 [T] COG0642 Signal transduction histidine kinase Length = 509 Score = 207 bits (526), Expect = 5e-53, Method: Compositional matrix adjust. Identities = 103/224 (45%), Positives = 155/224 (69%), Gaps = 2/224 (0%) Query: 170 TEFLAMMSHEIRTPMNGVVGMIDLLMETELAPEQKEYTEIIRKSADTLITVINDILDFTK 229 +EFLA MSHEIRTP+NG++G +LL ++EL+P Q++Y I+KSA++L+ +IN+ILDF+K Sbjct: 285 SEFLANMSHEIRTPLNGILGFTNLLQKSELSPRQQDYLTTIQKSAESLLGIINEILDFSK 344 Query: 230 MESGKMEMEEQLFELQTTIQEVFSLFSAEAGKKNLELAYFIDQKLPRLIYGDMARLRQVL 289 +E+GK+ +E F L+ IQ+ ++ + A +K LEL + + P + GD RL+Q+L Sbjct: 345 IEAGKLVLENLPFNLRDLIQDALTMLAPAAHEKQLELVSLVYRDTPIQLQGDPQRLKQIL 404 Query: 290 INLVANAVKFTNQGGVYLVASSVPSE-DNKLTVEFTIKDTGIGISPEKCDRLFQPFSQLD 348 NLV NA+KFT QGG V + + E D++ + +++DTGIG+S E LF+ FSQ D Sbjct: 405 TNLVGNAIKFT-QGGTVAVRAMLEDESDDRAQLRISVQDTGIGLSEEDQQALFKAFSQAD 463 Query: 349 SSMTRKYGGTGLGLAICKSLVGMMGGEIRVESMEEKGATFVFTI 392 +S++R+ GGTGLGL I K L+ MGGEI V+S +GA F ++ Sbjct: 464 NSLSRQAGGTGLGLVISKRLIEQMGGEIGVDSTPGEGAEFWISL 507 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.134 0.370 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 36,128,619 Number of extensions: 1386536 Number of successful extensions: 5558 Number of sequences better than 1.0e-05: 621 Number of HSP's gapped: 4948 Number of HSP's successfully gapped: 747 Length of query: 556 Length of database: 38,378,431 Length adjustment: 111 Effective length of query: 445 Effective length of database: 25,576,357 Effective search space: 11381478865 Effective search space used: 11381478865 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 118 (50.1 bits)