BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0167.0008.p (517 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH1910 [T] COG4753 Response regulator containing CheY-like recei... 297 3e-80 BH0793 [T] COG4753 Response regulator containing CheY-like recei... 117 3e-26 BH2109 [T] COG4753 Response regulator containing CheY-like recei... 102 2e-21 SPy1587 [T] COG4753 Response regulator containing CheY-like rece... 100 6e-21 SP0156 [T] COG4753 Response regulator containing CheY-like recei... 93 1e-18 >BH1910 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 506 Score = 297 bits (761), Expect = 3e-80, Method: Compositional matrix adjust. Identities = 187/522 (35%), Positives = 270/522 (51%), Gaps = 34/522 (6%) Query: 2 MIKVLIVDDEPKLREGLRALIPWGQLGFTVVATAANGLQALEKYHIHDPELIVVDIRMPG 61 M V+IVDDE +REGL+ALI W + GF V+ TA NG + KY P+L++VDIRMP Sbjct: 1 MYDVMIVDDEAMVREGLKALISWEEYGFRVIDTARNGKEGFTKYRQLSPDLMIVDIRMPE 60 Query: 62 MDGLELIGELRNEGSTSHVLILSGHADFDYAKRAIGYRIDGYLLKPVDEEEMISLLKELR 121 +DGL LI +R E S H +ILSGH+DF+YAK+A+G + D YLLKP+DE+E+I LK++ Sbjct: 61 VDGLSLIESIRAEDSAIHFIILSGHSDFNYAKKALGCQCDDYLLKPLDEDELIDSLKKVY 120 Query: 122 ETIDREDRFSRWNEEEPTRNRESLLRALLQ-------PPAEESGADDPGKQAAALGLTPG 174 I R + E + E +L LL+ P +E Q A + Sbjct: 121 GRITRHHQVHELVERVQEKQVEMVLTELLEGTPLSEIPIGKEHNFFATDYQVALVENRQD 180 Query: 175 RVEVVLIELLAPAHXXXXXXXXXXXXXXQHFSGSGDRLFFTLPPYIGLLLKEPLQDGMRR 234 R+ L L+ + P YI ++ K + Sbjct: 181 RLTKQLKRLIEE---------------------QEEGYVIPFPEYIVIVCKNRFLQKRGK 219 Query: 235 ERLIEELAGLICPCGFNFTAAAGGAVPRPEEAAESFNAARDLLRRAFFYRKGMMLTADP- 293 + A + + A AG V + ES+ +A+ L + FF KG + TAD Sbjct: 220 DHRYHLFAKWLEEEELH--ACAGSKVVNLADIYESYQSAKRLYEKKFFVEKGRLFTADQL 277 Query: 294 SGMLFPDSGEADTEQVTDAESRLLLAVETGSRAAIEPLVQAISAGLIAAGGEEQQIKDTF 353 P++ E E D RL +++ G+ +++ + +I EE++IK Sbjct: 278 VDRSKPEAPEFSLESYAD---RLYYSIDIGNMEGCVAIIEELKNVVIVHLQEEKEIKVAL 334 Query: 354 VRILSTVLARLEPVYPEIRNNTVKHFPPIGELYQSHYLEDLQEQSVAFLAEIAGQMTSGV 413 ++ S +L +L +P + G++YQ +L + L + M +G Sbjct: 335 FQLYSNILHQLVRSHPNMEGVLEPLVMNAGDIYQFEHLPGIMAFLTKQLKYVIDCMDNGQ 394 Query: 414 KGNEIKKITELIQRRYNENLKLETLSELFSYNSAYLGKMFKNTTGEYFNTYLDKVRIEKA 473 ++K+ LI + Y +NL+LETL+ +F+YN AYLGK+FKN TGEYFNTYLDKVRIE Sbjct: 395 PDLLLRKMIALIHKDYAKNLRLETLASVFNYNRAYLGKLFKNYTGEYFNTYLDKVRIENG 454 Query: 474 KEFLAQGMKVYEVAEKVGYMNSDYFNAKFRKYVGTSPSSFRK 515 K L +G KVYEVAEK+GY N DYF+ KF+KYVG SPS+FRK Sbjct: 455 KRLLQKGYKVYEVAEKIGYANVDYFHRKFKKYVGVSPSTFRK 496 >BH0793 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 508 Score = 117 bits (294), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 57/125 (45%), Positives = 84/125 (67%) Query: 2 MIKVLIVDDEPKLREGLRALIPWGQLGFTVVATAANGLQALEKYHIHDPELIVVDIRMPG 61 MI+V++VDDEP + EGL+ LI WGQLG+ +VATA NG++ALE +L++ DI+MP Sbjct: 1 MIRVMLVDDEPLILEGLKHLIDWGQLGYEIVATARNGVEALEIAKYVSFDLLITDIKMPE 60 Query: 62 MDGLELIGELRNEGSTSHVLILSGHADFDYAKRAIGYRIDGYLLKPVDEEEMISLLKELR 121 GLELI L T ++LSG +F + K+ + I+ YLLKP++E+E+IS L ++ Sbjct: 61 KTGLELIAALNEREKTIRSIVLSGFQEFHFVKQGLTLGIENYLLKPINEKELISTLSHVK 120 Query: 122 ETIDR 126 E I+ Sbjct: 121 EKINH 125 Score = 73.2 bits (178), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 33/99 (33%), Positives = 62/99 (62%), Gaps = 1/99 (1%) Query: 418 IKKITELIQRRYNENLKLETLSELFSYNSAYLGKMFKNTTGEYFNTYLDKVRIEKAKEFL 477 I+ + + I + ++++L L+TL F N YLG++F+ G F YL+++RI++AK+ L Sbjct: 405 IQTVLQHIHQHFSQDLSLKTLGHSFHINPIYLGQLFQREVGCSFTKYLNQLRIDRAKKLL 464 Query: 478 AQGM-KVYEVAEKVGYMNSDYFNAKFRKYVGTSPSSFRK 515 + ++ +KVGY ++ YF +F+KY +P+ +RK Sbjct: 465 LNSYDRAGQIGKKVGYGDATYFYKQFKKYEAMTPTEWRK 503 >BH2109 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 525 Score = 102 bits (253), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 51/127 (40%), Positives = 82/127 (64%), Gaps = 1/127 (0%) Query: 2 MIKVLIVDDEPKLREGLRALIPWGQLGFTVVATAANGLQALEKYHIHDPELIVVDIRMPG 61 M KVL+ DDE +R GL++LI W + G+ V A A NG A + P+L++ DIRMP Sbjct: 1 MYKVLLADDEFFVRHGLKSLIEWEKCGYEVAAEADNGEDAFKLVQEIKPDLVITDIRMPV 60 Query: 62 MDGLELIGELRNEGS-TSHVLILSGHADFDYAKRAIGYRIDGYLLKPVDEEEMISLLKEL 120 DGL+LI ++ S + +I+SG+ DF YA++A+ + ++LKP+D++E+ + L +L Sbjct: 61 FDGLQLIQKVNETLSFNTKFIIISGYNDFSYAQKAVRFGAVDFVLKPIDQDELEAALIKL 120 Query: 121 RETIDRE 127 T+D+E Sbjct: 121 AATLDQE 127 Score = 87.0 bits (214), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 42/100 (42%), Positives = 68/100 (68%), Gaps = 1/100 (1%) Query: 416 NEIKKITELIQRRYNENLKLETLSELFSYNSAYLGKMFKNTTGEYFNTYLDKVRIEKAKE 475 ++I K+ I+ Y+EN+ L++++ LF N Y+G++FK T G YF YL K+R+ +AK+ Sbjct: 421 SDIYKVKTYIENHYHENISLKSIASLFYMNPVYMGQLFKKTFGVYFKEYLLKLRMNEAKK 480 Query: 476 FLAQ-GMKVYEVAEKVGYMNSDYFNAKFRKYVGTSPSSFR 514 L Q M+VYEVAE+VG+ ++DYF +F K +P+ +R Sbjct: 481 LLRQTDMRVYEVAERVGFGSTDYFVTQFEKINKMTPTEYR 520 >SPy1587 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 494 Score = 100 bits (249), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 50/124 (40%), Positives = 77/124 (62%) Query: 2 MIKVLIVDDEPKLREGLRALIPWGQLGFTVVATAANGLQALEKYHIHDPELIVVDIRMPG 61 M KVL+VDDE + +GL +I W LGF VV TA +G +AL + ++++ D+ MPG Sbjct: 1 MYKVLLVDDEYMILQGLTMIIDWQALGFEVVQTARSGKEALAYLTQYPVDVMISDVTMPG 60 Query: 62 MDGLELIGELRNEGSTSHVLILSGHADFDYAKRAIGYRIDGYLLKPVDEEEMISLLKELR 121 M GL+LI + LILSG+ +F Y ++A+ GYLLKPVD+ E+ + +K+ + Sbjct: 61 MTGLDLIEAAKTYHPQLQTLILSGYQEFSYVQKAMELETKGYLLKPVDKAELQAKMKQFK 120 Query: 122 ETID 125 + +D Sbjct: 121 DWLD 124 Score = 68.9 bits (167), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 49/184 (26%), Positives = 88/184 (47%), Gaps = 28/184 (15%) Query: 359 TVLARLEPVYPEIRN-----NTVKH------------FPPIGELYQSHYLEDLQE-QSV- 399 T+L++LE ++ E++ VKH FP + ++ ++ + + QS+ Sbjct: 297 TILSKLEAIFDEMKTLNFSPEDVKHVSFLLFSDIYRQFPILDKMTYLSMVKTIHDSQSID 356 Query: 400 AFLAEIAGQMTSGVKGNE--------IKKITELIQRRYNENLKLETLSELFSYNSAYLGK 451 L E+ + + N + + + I++ Y++ L L+ +++ N YLG+ Sbjct: 357 CILRELKKVLDVTNQNNSPEKRYSDLVSETIDCIRKEYHQELTLKAIADRLHVNGVYLGQ 416 Query: 452 MFKNTTGEYFNTYLDKVRIEKAKE-FLAQGMKVYEVAEKVGYMNSDYFNAKFRKYVGTSP 510 FKN T F YL+ VRI+KA++ L + E+A + GY + YF F+K G SP Sbjct: 417 CFKNETERSFTQYLNHVRIQKAQQLLLYTNQSINEIAYETGYNTNHYFIKMFKKLNGLSP 476 Query: 511 SSFR 514 FR Sbjct: 477 KEFR 480 >SP0156 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 428 Score = 92.8 bits (229), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 48/119 (40%), Positives = 79/119 (66%) Query: 2 MIKVLIVDDEPKLREGLRALIPWGQLGFTVVATAANGLQALEKYHIHDPELIVVDIRMPG 61 M KVL+VDDE + EGL+ LIP+ + VVATA++ +ALE + ++I+ D+ MP Sbjct: 1 MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYVQENPVDVIISDVNMPD 60 Query: 62 MDGLELIGELRNEGSTSHVLILSGHADFDYAKRAIGYRIDGYLLKPVDEEEMISLLKEL 120 GL++I E++ + ++LSG+ +FDY KRA+ + YL+KPVD+ E+ +LL+++ Sbjct: 61 KTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDYLVKPVDKVELGNLLEKI 119 Score = 62.4 bits (150), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 2/123 (1%) Query: 396 EQSVAFLAEIAGQMTSGVKGNE-IKKITELIQRRYNENLKLETLSELFSYNSAYLGKMFK 454 ++ V+++ E + NE + + E+I R Y + L L+ +S+ N YLG++ K Sbjct: 301 DELVSYIKETLISFFGQYRMNENVVSVLEVIGRDYQKELSLKDISKALFINPVYLGQLIK 360 Query: 455 NTTGEYFNTYLDKVRIEKAKEFL-AQGMKVYEVAEKVGYMNSDYFNAKFRKYVGTSPSSF 513 T F L+K RI+ A++ L + + ++ VGY N YF FRK G SP ++ Sbjct: 361 RETDSTFAELLNKQRIKAAQQLLLSTSDSIEDICYAVGYSNLGYFYKVFRKLCGKSPKAY 420 Query: 514 RKN 516 RK Sbjct: 421 RKQ 423 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.137 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 37,398,769 Number of extensions: 1633924 Number of successful extensions: 5283 Number of sequences better than 1.0e-05: 361 Number of HSP's gapped: 5283 Number of HSP's successfully gapped: 373 Length of query: 517 Length of database: 38,378,431 Length adjustment: 111 Effective length of query: 406 Effective length of database: 25,576,357 Effective search space: 10384000942 Effective search space used: 10384000942 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 118 (50.1 bits)