BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0166.0002.p (1064 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value lin2643 [T] COG0642 Signal transduction histidine kinase 167 9e-41 TM1654_2 [T] COG0642 Signal transduction histidine kinase 165 5e-40 PA0928_1 [T] COG0642 Signal transduction histidine kinase 152 2e-36 SA1515 [T] COG0642 Signal transduction histidine kinase 152 3e-36 BS_resE_4 [T] COG0642 Signal transduction histidine kinase 147 6e-35 >lin2643 [T] COG0642 Signal transduction histidine kinase Length = 182 Score = 167 bits (423), Expect = 9e-41, Method: Compositional matrix adjust. Identities = 0/387 (0%), Positives = 0/387 (0%), Gaps = 41/387 (10%) Query: 541 EIQGLASRVALAIERI--MMYEEIEHGRKLNQDIVNNVNEGIQFVNTEGVMQHINKALSQ 598 Sbjct: 225 - 283 Query: 599 LFHYEWAEGSLIPAEAWLDAFTGKSNESAELRSFYENAIAESALDSSTMKYSLGKEEIQH 658 Sbjct: 284 ------------------ 325 Query: 659 ------VDVYAIPVLRREDRI-GTLFVHRDITREYELDVMKSELVSTVSHELRTPLSSVL 711 Sbjct: 326 385 Query: 712 GFTELLLSKTMKPEKQLK-YLETIHKEAKRLTELINDFLDLQRMESGTQQYNVEPAHLSE 770 Sbjct: 386 445 Query: 771 IVLGVIDQ-----YKLSSTHHI---LFEDEAVHDEVAVDRDKIVQVLTNLLSNAIKFSPG 822 Sbjct: 446 ---- 501 Query: 823 SHEVKVMLHNEPGRILVRIQDQGLGIPKNQIGQLFQKFRRVDNSASKRIGGTGLGLAICK 882 Sbjct: 502 561 Query: 883 EIIEKHKGTIGIDSVEGEGSTVWFSLP 909 Sbjct: 562 588 >TM1654_2 [T] COG0642 Signal transduction histidine kinase Length = 272 Score = 165 bits (417), Expect = 5e-40, Method: Compositional matrix adjust. Identities = 96/264 (36%), Positives = 163/264 (61%), Gaps = 12/264 (4%) Query: 655 EIQHVDVYAIPV-LRREDRIGTLFVHRDITREYELDVMKSELVSTVSHELRTPLSSVLGF 713 E ++ V IPV L+ D+I + H D+T+E +LD M+ E ++TVSHELRTPL+S+ G+ Sbjct: 9 EKKYFHVKVIPVELKSGDKIFVILFH-DVTKERKLDEMRREFIATVSHELRTPLTSIHGY 67 Query: 714 TELLLSKTMKPEKQLK-YLETIHKEAKRLTELINDFLDLQRMESGTQQYNVEPAHLSEI- 771 E LL ++ ++ +K +L+ I +E+ R+T LIND LDL+++E + ++ L E+ Sbjct: 68 AETLLEDDLENKELVKRFLKIIEEESARMTRLINDLLDLEKIEESEANFEMKDVDLCEVI 127 Query: 772 --VLGVIDQYKLSSTHHILFEDEAVHDEVAVDRDKIVQVLTNLLSNAIKFS----PGSHE 825 V +I + ++ E E V V ++++++Q+L NL+ NA+K++ G + Sbjct: 128 EYVYRIIQPIAEENEVDLIVECEDVV--VRGNKERLIQMLLNLVDNAVKYTSLKEKGEKK 185 Query: 826 VKVMLHNEPGRILVRIQDQGLGIPKNQIGQLFQKFRRVDNSASKRIGGTGLGLAICKEII 885 V V ++ P ++V ++D G GIPK ++F+KF RVD + S+++GGTGLGL I K I+ Sbjct: 186 VWVRAYDTPDWVVVEVEDTGPGIPKEAQSRIFEKFYRVDKARSRKMGGTGLGLTIVKTIV 245 Query: 886 EKHKGTIGIDSVEGEGSTVWFSLP 909 +KH G I ++S +G+ + LP Sbjct: 246 DKHGGKIEVESEINQGTLMRVLLP 269 >PA0928_1 [T] COG0642 Signal transduction histidine kinase Length = 509 Score = 152 bits (385), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 106/301 (35%), Positives = 167/301 (55%), Gaps = 29/301 (9%) Query: 623 SNESAELRSFYENAIAESALDSSTMKYSLGKEEIQH-VDVYAIPVLRREDRIGTLFVHRD 681 SNE EL S N +AE+ L S+ +EE+QH +D V + + I + D Sbjct: 221 SNELDELASGI-NRMAET-LQSA-------QEEMQHNIDQATEDVRQNLETIEIQNIELD 271 Query: 682 ITREYELDV--MKSELVSTVSHELRTPLSSVLGFTELLLSKTMKPEKQLKYLETIHKEAK 739 + R+ L+ +KSE ++ +SHE+RTPL+ +LGFT LL + P +Q YL TI K A+ Sbjct: 272 LARKEALEASRIKSEFLANMSHEIRTPLNGILGFTNLLQKSELSPRQQ-DYLTTIQKSAE 330 Query: 740 RLTELINDFLDLQRMESGTQQYNVEPAHLSEIVLGVIDQYKLSSTHH--------ILFED 791 L +IN+ LD ++E+G P +L +++ + L+ H +++ D Sbjct: 331 SLLGIINEILDFSKIEAGKLVLENLPFNLRDLIQDAL--TMLAPAAHEKQLELVSLVYRD 388 Query: 792 EAVHDEVAVDRDKIVQVLTNLLSNAIKFSPGSH-EVKVMLHNEP---GRILVRIQDQGLG 847 + ++ D ++ Q+LTNL+ NAIKF+ G V+ ML +E ++ + +QD G+G Sbjct: 389 TPI--QLQGDPQRLKQILTNLVGNAIKFTQGGTVAVRAMLEDESDDRAQLRISVQDTGIG 446 Query: 848 IPKNQIGQLFQKFRRVDNSASKRIGGTGLGLAICKEIIEKHKGTIGIDSVEGEGSTVWFS 907 + + LF+ F + DNS S++ GGTGLGL I K +IE+ G IG+DS GEG+ W S Sbjct: 447 LSEEDQQALFKAFSQADNSLSRQAGGTGLGLVISKRLIEQMGGEIGVDSTPGEGAEFWIS 506 Query: 908 L 908 L Sbjct: 507 L 507 >SA1515 [T] COG0642 Signal transduction histidine kinase Length = 554 Score = 152 bits (385), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 88/266 (33%), Positives = 153/266 (57%), Gaps = 14/266 (5%) Query: 647 MKYSLGKEEIQHVDVYAIPVLRREDRI--GTLFVHRDITREYELDVMKSELVSTVSHELR 704 ++ ++ + ++ D+ +P+L R + G L V DIT +L+ ++ E V+ VSHEL+ Sbjct: 284 LEVAINQVHAKYFDISCVPILTRSQKSLQGILVVMHDITNLKQLENLRREFVANVSHELK 343 Query: 705 TPLSSVLGFTELLLSKTMKPEKQLK-YLETIHKEAKRLTELINDFLDLQRMESGTQQYNV 763 TP++S+ GF E L+ + L +L I KE+ R+ L+ D LDL +E T+ + Sbjct: 344 TPITSIKGFAETLIDGAKNDAESLDMFLNIILKESNRIESLVTDLLDLSHIEQHTE-LDT 402 Query: 764 EPAHLSEIVLGVIDQYKLSSTHHILFEDEAVHDEVAVD------RDKIVQVLTNLLSNAI 817 + +LS++ +ID + ++ ++H ++ D KI QV+TNLL+NAI Sbjct: 403 DYMNLSDLTRRIIDNMMTQANQ----KNISIHTDIEKDVIVKAQESKIAQVITNLLTNAI 458 Query: 818 KFSPGSHEVKVMLHNEPGRILVRIQDQGLGIPKNQIGQLFQKFRRVDNSASKRIGGTGLG 877 +S ++ V ++ + R++ +QD G+GI ++F++F RVD + S+ GGTGLG Sbjct: 459 NYSYEDGDINVRVYRDDFRVIFEVQDFGIGIKLEDQQRIFERFYRVDKARSRDSGGTGLG 518 Query: 878 LAICKEIIEKHKGTIGIDSVEGEGST 903 L+I K I+E H+G I ++S G+GST Sbjct: 519 LSITKHIVEAHQGNIEVNSQVGKGST 544 >BS_resE_4 [T] COG0642 Signal transduction histidine kinase Length = 269 Score = 147 bits (372), Expect = 6e-35, Method: Compositional matrix adjust. Identities = 83/246 (33%), Positives = 139/246 (56%), Gaps = 12/246 (4%) Query: 674 GTLFVHRDITREYELDVMKSELVSTVSHELRTPLSSVLGFTELLLSKTMKPEKQLKYL-E 732 G + V RD+T E LD ++ + ++ VSHELRTP+S + G++E ++ E+ K + + Sbjct: 27 GAVAVLRDMTEERRLDKLREDFIANVSHELRTPISMLQGYSEAIVDDIASSEEDRKEIAQ 86 Query: 733 TIHKEAKRLTELINDFLDLQRMESGTQQYNVEPAHLSEIV-------LGVIDQYKLSSTH 785 I+ E+ R+ L+ND LDL RMESG + E +++E + GV + ++ H Sbjct: 87 IIYDESLRMGRLVNDLLDLARMESGHTGLHYEKINVNEFLEKIIRKFSGVAKEKNIALDH 146 Query: 786 HILFEDEAVHDEVAVDRDKIVQVLTNLLSNAIKFSPGSHEVKVMLHNEPGRILVRIQDQG 845 I +E E D DK+ QV TNL+ NA++ + V + +H+ + + I+D G Sbjct: 147 DISLTEE----EFMFDEDKMEQVFTNLIDNALRHTSAGGSVSISVHSVKDGLKIDIKDSG 202 Query: 846 LGIPKNQIGQLFQKFRRVDNSASKRIGGTGLGLAICKEIIEKHKGTIGIDSVEGEGSTVW 905 GIP+ + +F++F + D + ++ GTGLGLAI K I+E H G+I + S +G+T Sbjct: 203 SGIPEEDLPFIFERFYKADKARTRGRAGTGLGLAIVKNIVEAHNGSITVHSRIDKGTTFS 262 Query: 906 FSLPVQ 911 F +P + Sbjct: 263 FYIPTK 268 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.316 0.133 0.372 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 70,654,840 Number of extensions: 2799417 Number of successful extensions: 6962 Number of sequences better than 1.0e-05: 276 Number of HSP's gapped: 6548 Number of HSP's successfully gapped: 278 Length of query: 1064 Length of database: 38,378,431 Length adjustment: 117 Effective length of query: 947 Effective length of database: 24,884,353 Effective search space: 23565482291 Effective search space used: 23565482291 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 121 (51.2 bits)