BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0164.0006.p (1065 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value aq_786 [V] COG0841 Cation/multidrug efflux pump 238 3e-62 mll1426 [V] COG0841 Cation/multidrug efflux pump 194 1e-48 jhp0903 [P] COG3696 Putative silver efflux pump 186 1e-46 CC2390 [P] COG3696 Putative silver efflux pump 183 1e-45 HP0969 [P] COG3696 Putative silver efflux pump 178 5e-44 >aq_786 [V] COG0841 Cation/multidrug efflux pump Length = 1000 Score = 238 bits (608), Expect = 3e-62, Method: Compositional matrix adjust. Identities = 193/770 (25%), Positives = 341/770 (44%), Gaps = 26/770 (3%) Query: 302 VKLGELANIEVTGKSE-SISRTNGKESIGIQIVKANDANTVDVVNGVKDKTDELKKQYK- 359 ++LG++A + E S++R NG ++ + + K NTV V++ +K + + ++ Sbjct: 247 LRLGDVARVYFGEDEERSLARFNGNRAVALLVFKQAKVNTVRVIDEIKSRMEFFRELLPP 306 Query: 360 SMDLTVLLDQGKPIEDSVNTMLSKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXA 419 + L D +++S+ + Sbjct: 307 DIKLDYTFDASVYVKESIRAAFEEIIIGVFLTAFTVYLFLGNLRLTLVPVFAIPVTILGT 366 Query: 420 VLCLRQMDITLNMMTLGAMTVAIGRVVDDSIVVIENIYRRLSLSGEKLRGRELISAATRE 479 + L Q+ +LN +TL A+ VA+G V+DD+IVV+E+I+RR E L E TR Sbjct: 367 IFFLYQLGYSLNTITLLALAVAVGIVIDDAIVVMESIHRR---REEGLPPFEAGVKGTRV 423 Query: 480 MFVPIMSSTIVTIAVFLPLAFVSGMVGELFLPFALTMVFALLASLIVAITLVPALAHSLF 539 + +++ST V I VFLP+ F+ G++G FALT++ A+ S +VAIT P+ L Sbjct: 424 VMFALLASTSVLIVVFLPVVFLKGVLGTFLKNFALTLIIAIGLSYLVAITFTPSATVRLI 483 Query: 540 RNGLKKGKNSHSEKPGRMAAGYQKILDWSLSHKLITFGVAVLLLVGSLFLIKPIGVSFMP 599 + +N + R + K L +SL HK I ++ + S++L + F+P Sbjct: 484 TQ--RPRENFFMKLYKRFEGSFDKALRFSLDHKFIVLLLSFFFVGLSVYLFPKVKKEFVP 541 Query: 600 SQEEKNVMLTFSPKAGQTLEDVKEQGLKAEKYILAQKHLDKMQYXXXXXXXXXXXXXXXX 659 +E M+ G + E VKE+ + E+ +L H+ K+ Sbjct: 542 HVDEGRFMVRMRMPVGTSFERVKEKAKEVERILLKNPHIAKVGMVVGEGVGGAGVHSGLF 601 Query: 660 LFYVTYDSDTPD----FDTVKENLIE----GLTKEVPXXXXXXXXXXXXXXXXXXXXXXX 711 Y+ S P V+ L E ++ E P Sbjct: 602 FVYLKERSQRPHQMVVMSEVRRELSELKNVKVSVEPPHGIGASAGRTTDLQYI------- 654 Query: 712 IFGDSLDQLKPVADEIAGIVQADTGNFKDGKTSLSEAYDQYTIVADQAKLSSLGLTAGQI 771 + G+ ++ LK +A + ++ F+D TSL + I + KLS LG++ + Sbjct: 655 VRGERIEVLKKIAKSMEEHF-SNVEGFRDVDTSLELSAPYVKISVKREKLSHLGVSVEDL 713 Query: 772 AMKLSPAGTRPVLTEVAMDGKNYNVYIETDKDTYSSIQEMEKATLTSPLGITVPIGEVAK 831 + LS + + + ++Y+ YI+ ++D I + + + + G +PI E+ Sbjct: 714 GLTLSLLFGKYRVGTYELGSESYDFYIKAEEDFVKEIHNLNRVYIRARNGELIPITELID 773 Query: 832 IENGTSPDSITREDGKMKVDVTAEIISSDVNSASNSVKEKIDALDLPDGVTVTFGGVTEQ 891 P S+TR + + A + D+ +A + V++ + +LP G T G ++ Sbjct: 774 FSIEAGPFSLTRYNRQYSFVFYANLEGIDLATARSLVEDWLKK-NLPFGYTYDTAGRVKE 832 Query: 892 INDTFGQLGVAMAAAIAIVYFVLVVTFGGGLAPFAILFSLPFTVIGXXXXXXXXGETLNV 951 F +++A ++ VY +L F PF +L +P + +G +LNV Sbjct: 833 FKKAFSGFVLSLAMSLIGVYMILASLFESLKHPFTVLLMVPLSALGVFGFMYLTDTSLNV 892 Query: 952 SALMGALMLIGIVVTNAIVLIDRVIHKEKEGMSTRQALLEAGATRLRPILMTALATIGAL 1011 S+ G ++L+GI+V +A++ I+R+I KEG + R+A+LEA RLRPILMT + + AL Sbjct: 893 SSYFGIILLVGIIVRDAVLFIERIIQLRKEGYAVREAILEARRERLRPILMTTITVVSAL 952 Query: 1012 LPLVSGLENSAGIISKGLGVTVIGGXXXXXXXXXXXXXXXYEFLMKFRSK 1061 LP+ GL + K L + VIGG YE LM+++ K Sbjct: 953 LPVALGL-TAGSEQRKPLAIAVIGGIASGLPLSLFLLPVLYE-LMEWKRK 1000 Score = 64.7 bits (156), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 48/196 (24%), Positives = 85/196 (43%), Gaps = 3/196 (1%) Query: 6 NFSLRNKFAIWLLTIIIVFAGLYSGLTMKQETLPNISIPYLSITTIYPGAAPEGVVNDVS 65 F + ++L + VF GLYS + + LP++ P + I+ YPGA P V +V+ Sbjct: 3 KFFIERPVTAFMLMLSFVFLGLYSLKLVPIDRLPDVEFPVVRISADYPGADPYVVDTNVT 62 Query: 66 KPLEQKLRNVDGVKTLTSNSLENASSITIEFDYGTNLDNATAAVREALNEV--ALPDNVQ 123 + +E+ + V G++++ S S +S+ + F ++D AT V A+ P V+ Sbjct: 63 RIIEEAVSTVSGIESIISRSYPGFASVVVTFTLDKDIDVATQEVSNAIQRAMRRFPKGVE 122 Query: 124 KPQISRFXXXXXXXXXXXXXXXXXXXXXXXTRIAENDIRPALEDIEGVASVQIAGQYVKE 183 P + + T A+ I+ LE + GV SV + G Sbjct: 123 PPTVVK-VDTSVAPIMVLLLYSDTADYQRLTYYADKVIKRELEKLYGVGSVSLGGFRDNV 181 Query: 184 VTLKFNQDKLKQYGLT 199 + ++ +L Y LT Sbjct: 182 LWVRLKVSELYGYELT 197 >mll1426 [V] COG0841 Cation/multidrug efflux pump Length = 1091 Score = 194 bits (492), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 44/769 (5%), Positives = 109/769 (14%), Gaps = 23/769 (2%) Query: 302 VKLGELANI-EVTGKSESISRTNGKESIGIQIVKANDANTVDVVNGVKDKTDELKKQY-K 359 G+ V R + V D T QY Sbjct: 253 GDTGQFVRGDAVRTTINKNGRQIVRAEGTANTTVVYAGGDQTVHGHALDTTLNGGYQYVH 312 Query: 360 SMDLTVLLDQGKPIEDSVNTMLSKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXA 419 + V A Sbjct: 313 NGGTASDTVVNSDGWQIVKNGGVAGNTTVNQKGRLQVDAGGTATNVTLKQGGALVTSTAA 372 Query: 420 VLCLRQMDITLNMMTLGAMTVAIGRVVDDSIVVIENIYRRLSLSGEKLRGRELISAATRE 479 + +++ A V + ++ G L R +A Sbjct: 373 TVTGINRLGAFSVVEGKADNVVLENGGRLDVLTGHTATNTRVDDGGTLDVRNGGTA--TT 430 Query: 480 MFVPIMSSTIVTIAVFLPLAFVSGMVGELFLPFALTMVFALLASLIVAITLVPALAHSLF 539 + + + + G + A ++ +S + Sbjct: 431 VSMGNGGVLLADSGAAVSGTRSDGKAFSIGGGQADALMLEKGSSFTLNAGDTATDTTVNG 490 Query: 540 RNGLKKGKNSHS--EKPGRMAAGYQKILDWSLSHKLITFGVAVLLLVGSLFLIKPIGVSF 597 + + A + I G A+L Sbjct: 491 -GLFTARGGTLAGTTTLNNGAILTLSGKTVNNDTLTIREGDALLQGGSLTGNGSVEKSGS 549 Query: 598 MPSQEEKNVMLTFSPKAGQTLED-VKEQGLKAEKYILAQKHLDKMQYXXXXXXXXXXXXX 656 + + + + ++ Sbjct: 550 GTLTVSNTTLTQKAVNLNEGTLTLNDSTVTTDVIA----QRGTALKLTGSTVLNGAIDPT 605 Query: 657 XXXLFYVTYD-SDTPDFDTVKENLIEGLTKEVPXXXXXXXXXXXXXXXXXXXXXXXIFGD 715 L + + + Sbjct: 606 NVTLASGATWNIPDNATVQSVVDDLSHAGQIHFTSTRTGKFVPATLKVKNLNGQNGTISL 665 Query: 716 SLD--QLKPVADEIAGIVQADTGNFKDGKTSLSEAYDQYTIVADQAKLSSLGLTAGQIAM 773 + + AD + TG + + ++ A Sbjct: 666 RVRPDMAQNNADRLVIDGGRATGKTILNLVNAGNSASGLATSGKGIQVVEAINGATTEEG 725 Query: 774 KLSPAGTRPVLTEVAMDGKNYNVYIETDKDTYSSIQEMEKATLTSPLGITVPIGEVAKIE 833 ++ + + + A++ + I ++ Sbjct: 726 AFVQGNRLQAGAFNYSLNRDSDESWYLRSENAYRAEVPLYASMLTQAMDYDRIVAGSRSH 785 Query: 834 NGTSPDSITREDGKMKVDVTAEIISS----DVNSASNSVKEKIDALDLPDGVTVTFGGVT 889 ++ + S+ + L + T Sbjct: 786 QTGVNGENNSVRLSIQGGHLGHDNNGGIARGATPESSGSYGFVR---LEGDLMRTEVAGM 842 Query: 890 EQINDTFGQLGVAMAAAIAIVYFVLVVTFGGGLAPFAILFSLPFTVIGXXXXXXXXGETL 949 +G G + L + + Sbjct: 843 SVTAGVYGAAGHSSVDVKDDDGSRAGTVRDDAGCLGGYLNLVHTSSGLWADIVAQGTRHS 902 Query: 950 NVSALMGALMLIGIVVTNAIVLIDRVIHKEKEGMSTRQALLEAGATRLRPILMTALATIG 1009 ++ + M Q L A Sbjct: 903 MKASSDNNDFRARGWGWLGSLETGLPFSITDNLMLEPQLQYTWQGLSLDDGKDNAGYVKF 962 Query: 1010 ALLPLVSGLENSAGIISKGLGVTVIGGXXXXXXXXXXXXXXXYEFLMKF 1058 S G + + Sbjct: 963 GHGSAQHVRAGFRL-GSHNDMTFGEGTSSRAPLRDSAKHSVSELPVNWW 1010 Score = 73.6 bits (179), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 12/222 (5%), Positives = 32/222 (14%), Gaps = 4/222 (1%) Query: 7 FSLRNKFAIWLLTIIIVFAGLYSGLTMKQETLPNISIPYLSITTIYPGAAPEGVVNDVSK 66 + + + + ++ + Sbjct: 5 VQKDIQGTTEPQFRNSHSRTSGTVTLYLPVSTFVGTGFFIHPQSKEKLMKRHLNTCYRLV 64 Query: 67 PLEQKLRNVDGVKTL-TSNSLENASSITIEF--DYGTNLDNATAAVREALNEVALPDNVQ 123 V + ++ + + A V Sbjct: 65 WNHMTGAFVVASELARARGKR-GGVAVALSLAAVTSLPVLAADIVVHPGETVNGGTLANH 123 Query: 124 KPQISRFXXXXXXXXXXXXXXXXXXXXXXXTRIAENDIRPALEDIEGVASVQIAGQYVKE 183 QI + + G G V + Sbjct: 124 DNQIVFGTTNGMTISTGLEYGPDNEANTGGQWVQDGGTANKTTVTSGGLQRVNPGGSVSD 183 Query: 184 VTLKFNQDKLKQYGLTEDTIKGIVQGSSLRVPLGLFTMEESQ 225 + + Q T+ G Q + + Sbjct: 184 TVISAGGGQSLQGRAVNTTLNGGEQWMHEGAIATGTVINDKG 225 >jhp0903 [P] COG3696 Putative silver efflux pump Length = 1091 Score = 186 bits (473), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 42/721 (5%), Positives = 105/721 (14%), Gaps = 27/721 (3%) Query: 332 IVKANDANTVDVVNGVKDKTDELKKQYKS-MDLTVLLDQGKPIEDSVNTMLSKXXXXXXX 390 V D T QY V Sbjct: 284 TTVVYAGGDQTVHGHALDTTLNGGYQYVHNGGTASDTVVNSDGWQIVKNGGVAGNTTVNQ 343 Query: 391 XXXXXXXXXXXXXXXXXXXXXXXXXXXXAVLCLRQMDITLNMMTLGAMTVAIGRVVDDSI 450 A + +++ A V + + Sbjct: 344 KGRLQVDAGGTATNVTLKQGGALVTSTAATVTGINRLGAFSVVEGKADNVVLENGGRLDV 403 Query: 451 VVIENIYRRLSLSGEKLRGRELISAATREMFVPIMSSTIVTIAVFLPLAFVSGMVGELFL 510 + AT + A Sbjct: 404 LTGHTATNTRV-DDGGTLDVRNGGTATTVSMGNGGVLLADSGAAVSGTRSDGKAFSIGGG 462 Query: 511 PFALTMVFALLASLIVAITLVPALAHSLFRNGLKKGKNSHSEKPGRMAAGYQKILDWSLS 570 M+ + + A + + + + Sbjct: 463 QADALMLEKGSSFTLNAGDTATDTTVNG----GLFTARGGTLAGTTTLNNGAILTLSGKT 518 Query: 571 H-KLITFGVAVLLLVGSLFLIKPIGVSFMPSQEEKNVMLTFSPKAGQTLEDVKEQGLKAE 629 + + G V T + L + + Sbjct: 519 VNNDTLTI-REGDALLQGGSLTGNGSVEKSGSGTLTVSNTTLTQKAVNLNEGTLTLNDST 577 Query: 630 KYILAQKHLDKMQYXXXXXXXXXXXXXXXXLFYV-TYDSDTPDFD---TVKENLIEGLTK 685 + + + + + + + + Sbjct: 578 VTT--DVIAQRGTALKLTGSTVLNGAIDPTNVTLASGATWNIPDNATVQSVVDDLSHAGQ 635 Query: 686 EVPXXXXXXXXXXXXXXXXXXXXXXXIFGD--------SLDQLKPVADEIAGIVQADTGN 737 + + A Sbjct: 636 IHFTSTRTGKFVPATLKVKNLNGQNGTISLRVRPDMAQNNADRLVIDGGRATGKTILNLV 695 Query: 738 FKDGKTSLSEAYDQYTIVADQAKLSSLGLTAGQIAMKLSPAGTRPVLTEVAMDGKNYNVY 797 G ++ A I +A + + AG D Y Sbjct: 696 -NAGNSASGLATSGKGIQVVEAINGATTEEGAFVQGNRLQAGAFNYSLNRDSDESWYLRS 754 Query: 798 IETDKDTYSSIQEMEKATLTSPLGITVPIGEVAKIENGTSPDSITREDGKMKVDVTAEII 857 + M + + + + ++ + G + D I Sbjct: 755 ENAYRAEVPLYASMLTQAMDYDRIVAGSRSHQTGVNGENNSVRLSIQGGHLGHDNNGGIA 814 Query: 858 SSDVNSASNSVKEKI-DALDLPDGVTVTFGGVTEQINDTFGQLGVAMAAAIAIVYFVLVV 916 +S S + + V + V Sbjct: 815 RGATPESSGSYGFVRLEGDLMRTEVAGMSVTAGVYGAAGHSSVDVKDDDGSRAGTVRDDA 874 Query: 917 TFGGGLAPFAILFSLPFTVIGXXXXXXXXGETLNVSALMGALMLIGIVVTNAIVLIDRVI 976 GG S + I + + + + + Sbjct: 875 GCLGGYLNLVHTSSGLWADIVAQGTRHSMKASSDNNDFRARGWGWLGSLETGLPFSITDN 934 Query: 977 HKEKEGMSTRQALLEAGATRLRPILMTALATIGALLPLVSGLENSAGI-ISKGLGVTVIG 1035 + + L + + + + ++ G G + Sbjct: 935 LMLEPQLQYTWQGLSLDDGKDNAGYVKFGHGSAQHVRAG--FRLGSHNDMTFGEGTSSRA 992 Query: 1036 G 1036 Sbjct: 993 P 993 Score = 58.2 bits (139), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 5/125 (4%), Positives = 18/125 (14%), Gaps = 2/125 (1%) Query: 1 MKSLINFSLRNKFAIWLLTIIIVFAGLYSGLTMKQETLPNISIPYLSITTIYPGAAPEGV 60 + + + + + L + I S + Sbjct: 2 HRYVQKDIQGTTEPQFRNSHSRTSGTVTLYLPVSTFVGTGFFIHPQSKEKLMKRHLNTCY 61 Query: 61 VNDVSKPLEQKLRNVDGVKTLTSNSLENASSITIEFDYGTNLDNATAAVREALNEVA--L 118 + + + + + L Sbjct: 62 RLVWNHMTGAFVVASELARARGKRGGVAVALSLAAVTSLPVLAADIVVHPGETVNGGTLA 121 Query: 119 PDNVQ 123 + Q Sbjct: 122 NHDNQ 126 >CC2390 [P] COG3696 Putative silver efflux pump Length = 1057 Score = 183 bits (465), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 164/638 (25%), Positives = 297/638 (46%), Gaps = 35/638 (5%) Query: 425 QMDITLNMMTLGAMTVAIGRVVDDSIVVIENIYRRLSLSGEKLRGR--------ELISAA 476 Q ++ N+M+LGA+ G +VD +++++EN RRL + + GR L++ A Sbjct: 402 QSKVSGNLMSLGALD--FGLIVDGAVIIVENCLRRLGEAQHRY-GRLLSRDERFALVAGA 458 Query: 477 TREMFVPIMSSTIVTIAVFLPLAFVSGMVGELFLPFALTMVFALLASLIVAITLVPALAH 536 T E+ P + ++ V++P+ ++G+ G++F P A+T+V AL A+L++++T VPA A Sbjct: 459 TSEVIRPSLFGVLIITLVYVPIFALTGVEGKMFHPMAITVVIALTAALVLSLTFVPA-AV 517 Query: 537 SLFRNGLKKGKNSHSEKPGRMAAGYQKILDWSLSHKLITFGVAVLLLVGSLFLIKPIGVS 596 +LF G + K + + R Y+ L+ +L ++ AVLL+ + F +G Sbjct: 518 ALFVTGKVEEKENLIMRGARRL--YEPALETALRLRVAFVAGAVLLVAIAAFAASRMGSE 575 Query: 597 FMPSQEEKNVMLTFSPKAGQTLEDVKEQGLKAEKYILAQKHLDKM--QYXXXXXXXXXXX 654 F+P+ +E ++ + G +L E + +D++ + Sbjct: 576 FVPNLDEGDIAMHALRIPGTSLSQAIAMQTALEAKVKTLPEVDRVVSKIGTAEVATDPMP 635 Query: 655 XXXXXLFYVTYDS-DTPDFDTVKENLI---EGLTKEVP-----XXXXXXXXXXXXXXXXX 705 F + D D PD + L+ E + +VP Sbjct: 636 PSVADTFIMLKDRKDWPDPRKPRAQLVAELEAVVAKVPGNNYEFTQPIQMRFNELLSGVR 695 Query: 706 XXXXXXIFGDSLDQLKPVADEIAGIVQADTGNFKDGKTSLSEAYDQYTIVADQAKLSSLG 765 +FGD LDQL + ++I G+++ G G ++ I D+A L+ LG Sbjct: 696 ADVAVKVFGDDLDQLLAIGEQIGGVIEGVEGAQDVGVEQVT-GLPVLQITPDRAALARLG 754 Query: 766 LTAGQIAMKLSPAGTRPVLTEVAMDGKNYNVYIETDKDTYSSIQEMEKATLTSPLGIT-- 823 L + ++ A V +V + ++V + + I ++ + + P I Sbjct: 755 LNVDDVQSVVATAIGGTVTGQVFEGDRRFDVVVRLPEAVRGRIDDIGRLRIPLPGAIDQP 814 Query: 824 ---VPIGEVAKIENGTSPDSITREDGKMKVDVTAEIISSDVNSASNSVKEKIDA-LDLPD 879 VP+ +VA+IE P+ I+REDGK ++ VTA + D+ S V+ K+ A ++LP Sbjct: 815 RGFVPLQDVARIEMVIGPNQISREDGKRRIVVTANVRGRDLGSFITEVQRKVGAQVELPT 874 Query: 880 GVTVTFGGVTEQINDTFGQLGVAMAAAIAIVYFVLVVTFGGGLAPFAILFS-LPFTVIGX 938 G +T+GG EQ+ +L + + AA+ +++ +L F + AI+FS +P + G Sbjct: 875 GYWITYGGAFEQLISAAQRLQLVVPAALLLIFGLLYALFRS-VKDAAIVFSGVPLALTGG 933 Query: 939 XXXXXXXGETLNVSALMGALMLIGIVVTNAIVLIDRVIHKEKEGMSTRQALLEAGATRLR 998 G L++SA +G + L G+ V N +V++ + ++G A+ E TRLR Sbjct: 934 VAALLLRGMPLSISAGVGFIALSGVAVLNGVVMVSFIRTLRQQGTDVDHAIREGALTRLR 993 Query: 999 PILMTALATIGALLPLVSGLENSAGIISKGLGVTVIGG 1036 P+LMTAL +P+ + A + + L VIGG Sbjct: 994 PVLMTALVASLGFVPMAFNVGAGAE-VQRPLATVVIGG 1030 >HP0969 [P] COG3696 Putative silver efflux pump Length = 1020 Score = 178 bits (451), Expect = 5e-44, Method: Compositional matrix adjust. Identities = 175/721 (24%), Positives = 327/721 (45%), Gaps = 27/721 (3%) Query: 332 IVKANDANTVDVVNGVKDKTDELKKQYKS-MDLTVLLDQGKPIEDSVNTMLSKXXXXXXX 390 ++ DANT +++ V K +ELK + + + V D+ + + ++ T+ Sbjct: 285 VLSLKDANTKEIITQVYQKLEELKPFLPNGVSINVFYDRSEFTQKAIATVSKTLIEAVVL 344 Query: 391 XXXXXXXXXXXXXXXXXXXXXXXXXXXXAVLCLRQMDITLNMMTLGAMTVAIGRVVDDSI 450 A + ++ D+TLN+M+LG + +AIG ++D ++ Sbjct: 345 IIITLFLFLGNLRASVAVGVILPLSLSVAFIFIKFSDLTLNLMSLGGLVIAIGMLIDSAV 404 Query: 451 VVIENIYRRLSLSGEKLRGRELISAATREMFVPIMSSTIVTIAVFLPLAFVSGMVGELFL 510 VV+EN + +LS + K I + +E+ V ++S ++ I F+P+ + G+ G++F Sbjct: 405 VVVENAFEKLS-ANTKTTKLHAIYRSCKEIAVSVVSGVVIIIVFFVPILTLQGLEGKMFR 463 Query: 511 PFALTMVFALLASLIVAITLVPALAHSLFRNGLKKGKNSHSEKPGRMAAGYQKILDWSLS 570 P A ++V+ALL +L+++IT++P ++ + LK +S + + Y +L++ + Sbjct: 464 PLAQSIVYALLGTLVLSITIIPVVSSLV----LKATPHSETFLTRFLNRIYAPLLEFFVH 519 Query: 571 H-KLITFGVAVLLLVGSLFLIKPIGVSFMPSQEEKNVMLTFSPKAGQTLEDVKEQGLKAE 629 + K + G A + L+ SL L +G +FMP +E +V+L+ +L+ ++ L E Sbjct: 520 NPKKVILG-AFVFLIASLSLFPFVGKNFMPVLDEGDVVLSVETTPSISLDQSRDLMLNIE 578 Query: 630 KYILAQKHLDKMQYXXXXXXXXXXXXXXXXLFYV-TYDSDTPDFD---TVKENLIEGLTK 685 I +KH+ +++ L T+ S P + K+ L+E + Sbjct: 579 SAI--KKHVKEVKSIVARTGSDELGLDLGGLNQTDTFISFIPKKEWSVKTKDELLEKIMD 636 Query: 686 EVPXXXXXXXXXXXXXXXXXXXXXXXIFGD--------SLDQLKPVADEIAGIVQADTGN 737 + + GD + +L ++ +IA ++ G+ Sbjct: 637 SLKDFKGINFSFTQPIEMRISEMLTGVRGDLAVKIFGDGISELNELSFQIAQALKGIKGS 696 Query: 738 FKDGKTSLSEAYDQYTIVADQAKLSSLGLTAGQIAMKLSPAGTRPVLTEVAMDGKNYNVY 797 + T+L+E + + ++ ++ +G+T+ + + L A V+ + V Sbjct: 697 -SEVLTTLNEGVNYLYVTPNKESMADVGITSDEFSKFLKSALEGLVVDVIPTGISRTPVM 755 Query: 798 IETDKDTYSSIQEMEKATLTSPLGITVPIGEVAKIENGTSPDSITREDGKMKVDVTAEII 857 I + D SSI +++ LTS G+ VPI +AKIE P S+ RE+ V + ++ Sbjct: 756 IRQESDFASSITKIKSLALTSKYGVLVPITSIAKIEEVDGPVSVVRENSMRMSVVRSNVV 815 Query: 858 SSDVNSASNSVKEKI-DALDLPDGVTVTFGGVTEQINDTFGQLGVAMAAAIAIVYFVLVV 916 D+ S K+ I + LP +T+GG E +L + +I ++F+L Sbjct: 816 GRDLKSFVEEAKKVIAQNIKLPPSYYITYGGQFENQQRANKRLSTVIPLSILAIFFILFF 875 Query: 917 TFGGGLAPFAILFSLPFTVIGXXXXXXXXGETLNVSALMGALMLIGIVVTNAIVLIDRVI 976 TF IL ++PF V G GE ++V A +G + L GI V N +V+I Sbjct: 876 TFKSIPLALLILLNIPFAVTGGLIALFAVGEYISVPASVGFIALFGIAVLNGVVMIGYFK 935 Query: 977 HKEKEGMSTRQALLEAGATRLRPILMTALATIGALLPLVSGLENSAGI-ISKGLGVTVIG 1035 +G S + +L RLRP+LMTA LLPL+ +S G + K L + V+G Sbjct: 936 ELLLQGKSVEECVLLGAKRRLRPVLMTACIAGLGLLPLL--FSHSVGSEVQKPLAIVVLG 993 Query: 1036 G 1036 G Sbjct: 994 G 994 Score = 58.5 bits (140), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 44/125 (35%), Positives = 70/125 (56%), Gaps = 2/125 (1%) Query: 1 MKSLINFSLRNKFAIWLLTIIIVFAGLYSGLTMKQETLPNISIPYLSITTIYPGAAPEGV 60 + S+I FSLR + + + I+I+F G YS + + P+IS + I PG++PE + Sbjct: 3 LASIIEFSLRQRVIVIVGAILILFFGTYSFINTPVDAFPDISPTQVKIILKLPGSSPEEM 62 Query: 61 VNDVSKPLEQKLRNVDGVKTLTSNSLENASSITIEFDYGTNLDNATAAVREALNEVA--L 118 N++ +PLE +L + G K+L S S + S ITI+FD ++ A V E L+ V L Sbjct: 63 ENNIVRPLELELLGLKGQKSLRSVSKYSISDITIDFDDSVDIYLARNIVNERLSSVMKDL 122 Query: 119 PDNVQ 123 P V+ Sbjct: 123 PVGVE 127 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.317 0.134 0.364 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 60,072,373 Number of extensions: 2237432 Number of successful extensions: 8972 Number of sequences better than 1.0e-05: 129 Number of HSP's gapped: 8537 Number of HSP's successfully gapped: 410 Length of query: 1065 Length of database: 38,378,431 Length adjustment: 117 Effective length of query: 948 Effective length of database: 24,884,353 Effective search space: 23590366644 Effective search space used: 23590366644 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 121 (51.2 bits)