BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0157.0036.p (277 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC0317 [T] COG0642 Signal transduction histidine kinase 242 4e-64 TM1654_2 [T] COG0642 Signal transduction histidine kinase 124 2e-28 SA1322 [T] COG0642 Signal transduction histidine kinase 119 4e-27 lin2643 [T] COG0642 Signal transduction histidine kinase 119 7e-27 BS_phoR_3 [T] COG0642 Signal transduction histidine kinase 115 7e-26 >CAC0317 [T] COG0642 Signal transduction histidine kinase Length = 498 Score = 242 bits (618), Expect = 4e-64, Method: Compositional matrix adjust. Identities = 123/264 (46%), Positives = 169/264 (64%) Query: 1 VTEGNLDFRVKIDSKDELGQLGMAFEEXXXXXXXXXXXXXXYESNRKELITNISHDLKTP 60 + GNLDF+V+ +S DE+G+L AF+ YE+NRKELI+NISHDLKTP Sbjct: 224 IKHGNLDFKVRAESSDEIGELCDAFDSMRKKLKESVELQAQYENNRKELISNISHDLKTP 283 Query: 61 ITAIKGYVDGILEGVADSPEKNEKYMRTIAAKAGEMDHLIDELFLFSKLDMQKLPFSFES 120 IT+IKGY++GI +GVAD+PEK EKY+ TI K M++LI+EL +SKLD++KLPF F Sbjct: 284 ITSIKGYIEGIRDGVADTPEKMEKYVNTIYNKTQSMNYLIEELLTYSKLDLKKLPFYFID 343 Query: 121 VPILPFLKDWAXXXXXXXXXXXXXXXIDMNGGEAARISVDRDSFKRVLGNIIQNSLKYMD 180 + + ++ D D + A + +D + RV+ NII NS+KYMD Sbjct: 344 MDFVSYMNDLMEEFKFDVEKNNMEFSYDNHIKGKANVRIDVQNINRVISNIISNSIKYMD 403 Query: 181 KPEKRITVQTLVEGKNFTLAIGDNGPGIPPEAAGHIFERFYRAEQSRNTNTGGSGLGLAI 240 K +I+V+ + + I DNG GI EA ++F+RFYR + SRNT+ GGSGLGLAI Sbjct: 404 KEHGKISVEVDSNNEEVLVGIKDNGMGISEEALPYVFDRFYREDFSRNTSKGGSGLGLAI 463 Query: 241 ARQIILEHGGTIHADSKEGEGTEI 264 ++II EHGG+I A S++G GTEI Sbjct: 464 CKKIIEEHGGSIWAKSQKGHGTEI 487 >TM1654_2 [T] COG0642 Signal transduction histidine kinase Length = 272 Score = 124 bits (311), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 66/227 (29%), Positives = 125/227 (55%), Gaps = 6/227 (2%) Query: 46 RKELITNISHDLKTPITAIKGYVDGILEGVADSPEKNEKYMRTIAAKAGEMDHLIDELFL 105 R+E I +SH+L+TP+T+I GY + +LE ++ E +++++ I ++ M LI++L Sbjct: 46 RREFIATVSHELRTPLTSIHGYAETLLEDDLENKELVKRFLKIIEEESARMTRLINDLLD 105 Query: 106 FSKLDMQKLPFSFESVPILPFLKDWAXXXXXXXXXXXXXXXIDMNGGEAARISVDRDSFK 165 K++ + F + V + ++ ++ E + +++ Sbjct: 106 LEKIEESEANFEMKDVDLCEVIEYVYRIIQPIAEENEVDLIVE---CEDVVVRGNKERLI 162 Query: 166 RVLGNIIQNSLKYM---DKPEKRITVQTLVEGKNFTLAIGDNGPGIPPEAAGHIFERFYR 222 ++L N++ N++KY +K EK++ V+ + + D GPGIP EA IFE+FYR Sbjct: 163 QMLLNLVDNAVKYTSLKEKGEKKVWVRAYDTPDWVVVEVEDTGPGIPKEAQSRIFEKFYR 222 Query: 223 AEQSRNTNTGGSGLGLAIARQIILEHGGTIHADSKEGEGTEIRIVLP 269 +++R+ GG+GLGL I + I+ +HGG I +S+ +GT +R++LP Sbjct: 223 VDKARSRKMGGTGLGLTIVKTIVDKHGGKIEVESEINQGTLMRVLLP 269 >SA1322 [T] COG0642 Signal transduction histidine kinase Length = 588 Score = 119 bits (299), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 69/224 (30%), Positives = 115/224 (51%), Gaps = 3/224 (1%) Query: 46 RKELITNISHDLKTPITAIKGYVDGILEGVADSPEKNEKYMRTIAAKAGEMDHLIDELFL 105 +K+ I N+SH+L+TPI+ ++GY + I++G+ P++ ++ + + ++ ++ L++EL Sbjct: 365 KKDFIANVSHELRTPISLLQGYTESIVDGIVTEPDEIKESLAVVLDESKRLNRLVNELLN 424 Query: 106 FSKLDMQKLPFSFESVPILPFLKDWAXXXXXXXXXXXXXXXIDMNGGEAARISVDRDSFK 165 +++D + L + E PI L + N + S D D Sbjct: 425 VARMDAEGLSVNKEVQPIAALLDKMKIKYRQQADDLGLN--MTFNYCKKRVWSYDMDRMD 482 Query: 166 RVLGNIIQNSLKYMDKPEKRITVQTLVEGKNFTLAIGDNGPGIPPEAAGHIFERFYRAEQ 225 +VL N+I N+ +Y KP I + L I D G GI PE +F+RFY+ + Sbjct: 483 QVLTNLIDNASRYT-KPGDEIAITCDENESEDILYIKDTGTGIAPEHLQQVFDRFYKVDA 541 Query: 226 SRNTNTGGSGLGLAIARQIILEHGGTIHADSKEGEGTEIRIVLP 269 +R G+GLGL I + II EHGG+I S+ G+GT I LP Sbjct: 542 ARTRGKQGTGLGLFICKMIIEEHGGSIDVKSELGKGTTFIIKLP 585 >lin2643 [T] COG0642 Signal transduction histidine kinase Length = 182 Score = 119 bits (297), Expect = 7e-27, Method: Compositional matrix adjust. Identities = 0/227 (0%), Positives = 0/227 (0%), Gaps = 1/227 (0%) Query: 43 ESNRKELITNISHDLKTPITAIKGYVDGILEGVADSPEKNEKYMRTIAAKAGEMDHLIDE 102 Sbjct: 363 422 Query: 103 LFLFSKLDMQKLPFSFESVPILPFLKDWAXXXXXXXXXXXXXXXIDMNGGEAARISVDRD 162 Sbjct: 423 482 Query: 163 SFKRVLGNIIQNSLKYMDKPEKRITVQTLVEGKNFTLAIGDNGPGIPPEAAGHIFERFYR 222 Sbjct: 483 - 541 Query: 223 AEQSRNTNTGGSGLGLAIARQIILEHGGTIHADSKEGEGTEIRIVLP 269 Sbjct: 542 588 >BS_phoR_3 [T] COG0642 Signal transduction histidine kinase Length = 431 Score = 115 bits (288), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 11/227 (4%), Positives = 35/227 (15%), Gaps = 4/227 (1%) Query: 43 ESNRKELITNISHDLKTPITAIKGYVDGILEGVADSPEKNEKYMRTIAAKAGEMDHLIDE 102 + + TP + + ++ Sbjct: 48 WNLLRLSWWLWVDRSMTPPPGRGSWEPLLYGLHQMQLRNKKRRRELGNLIKRFRSGAESL 107 Query: 103 LFLFSKLDMQKLPFSFESVPILPFLKDWAXXXXXXXXXXXXXXXIDMNGGEAARISVDRD 162 + F + W + S + Sbjct: 108 PDAVVLTTEEGGIFWCNGLAQQILGLRWPEDNGQNILNLLRYPEFTQ-YLKTRDFSRPLN 166 Query: 163 SFKRVLGNIIQNSLKYMDKPEK-RITVQTLVEGKNFTLAIGDNGPGIPPEAAGHIFERFY 221 ++ + Y ++ + + + + A + + E + Sbjct: 167 LVLNTGRHLEIRVMPYT--HKQLLMVARDVTQMHQLEGARRNFFANVSHELRTPLTVLQG 224 Query: 222 RAEQSRNTNTGGSGLGLAIARQIILEHGGTIHADSKEGEGTEIRIVL 268 E G+ A+ Sbjct: 225 YLEMMNEQPLEGAVREKALHTMREQTQRMEGLVKQLLTLSKIEAAPT 271 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.315 0.137 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 19,551,709 Number of extensions: 791067 Number of successful extensions: 3763 Number of sequences better than 1.0e-05: 247 Number of HSP's gapped: 3504 Number of HSP's successfully gapped: 254 Length of query: 277 Length of database: 38,378,431 Length adjustment: 105 Effective length of query: 172 Effective length of database: 26,268,361 Effective search space: 4518158092 Effective search space used: 4518158092 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 115 (48.9 bits)