BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0157.0025.p (888 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value MT1678_1 [S] COG2898 Uncharacterized conserved protein 101 6e-21 Rv1640c_1 [S] COG2898 Uncharacterized conserved protein 100 1e-20 lin1803_1 [S] COG0392 Predicted integral membrane protein 69 3e-11 >MT1678_1 [S] COG2898 Uncharacterized conserved protein Length = 636 Score = 101 bits (251), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 84/338 (24%), Positives = 137/338 (40%), Gaps = 9/338 (2%) Query: 534 AIAGLVMAWLLITLFFILRPNRLTNKGASDAELARLRKFLE-HEQGNLLTHVLFAGDKSF 592 AI GL A+ LI +L ++ + + + + +R L+ + + + L + DKS Sbjct: 285 AIFGLFGAFALIGAAIVLFLSQRADNALTGEDESAIRGLLDLYGKDDSLGYFATRRDKSV 344 Query: 593 FWACNDQVLIPYAIVRREFVVLGDPIGKENLVSEAIQESQRFADLYDLTVVFYQVSPHYL 652 +A + + I Y + + GDP+G +A+ R Y S Sbjct: 345 VFASSGRACITYRVEVGVCLASGDPVGDHRAWPQAVDAWLRLCQTYGWAPGVMGASSQGA 404 Query: 653 PIYHENGYRFFKLGEEALVSLEHFTLSGKPSASLRSVTNRFEREGFRFEVVQPPH-PEDL 711 Y E G +LG+EA++ F LSG +R R R G + + ED Sbjct: 405 QTYREAGLTALELGDEAILRPADFKLSGPEMRGVRQAVTRARRAGLTVRIRRHRDIAEDE 464 Query: 712 MKQLYEISQKWLDGKKEKGFS--LGWFDEDYXXXXXXXXXXXPNGEIIAFASLAPGYDNG 769 M Q + W D + E+GFS LG + P+ +++A SL P G Sbjct: 465 MAQTITRADSWRDTETERGFSMALGRLGDPADSDCLLVEAIDPHNQVLAMLSLVPWGTTG 524 Query: 770 NTLSVDLMRNLPVKPNGTMDHLFVSLLKWAKEQGYAYFNLGMAPLSSVGQTQSAIREEKL 829 +S+DLMR P PNGT++ + L A+ G +L A + + + + + Sbjct: 525 --VSLDLMRRSPQSPNGTIELMVSELALHAESLGITRISLNFAVFRAAFEQGAQLGAGPV 582 Query: 830 AHL---VFKHGGHWYGFLGLRKYKEKFSPVWEPRYLAY 864 A L + W+ L + K+ P W PRY Y Sbjct: 583 ARLWRGLLVFFSRWWQLETLYRSNMKYQPEWVPRYACY 620 >Rv1640c_1 [S] COG2898 Uncharacterized conserved protein Length = 677 Score = 100 bits (249), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 84/338 (24%), Positives = 137/338 (40%), Gaps = 9/338 (2%) Query: 534 AIAGLVMAWLLITLFFILRPNRLTNKGASDAELARLRKFLE-HEQGNLLTHVLFAGDKSF 592 AI GL A+ LI +L ++ + + + + +R L+ + + + L + DKS Sbjct: 272 AIFGLFGAFALIGAAIVLFLSQRADNALTGEDESAIRGLLDLYGKDDSLGYFATRRDKSV 331 Query: 593 FWACNDQVLIPYAIVRREFVVLGDPIGKENLVSEAIQESQRFADLYDLTVVFYQVSPHYL 652 +A + + I Y + + GDP+G +A+ R Y S Sbjct: 332 VFASSGRACITYRVEVGVCLASGDPVGDHRAWPQAVDAWLRLCQTYGWAPGVMGASSQGA 391 Query: 653 PIYHENGYRFFKLGEEALVSLEHFTLSGKPSASLRSVTNRFEREGFRFEVVQPPH-PEDL 711 Y E G +LG+EA++ F LSG +R R R G + + ED Sbjct: 392 QTYREAGLTALELGDEAILRPADFKLSGPEMRGVRQAVTRARRAGLTVRIRRHRDIAEDE 451 Query: 712 MKQLYEISQKWLDGKKEKGFS--LGWFDEDYXXXXXXXXXXXPNGEIIAFASLAPGYDNG 769 M Q + W D + E+GFS LG + P+ +++A SL P G Sbjct: 452 MAQTITRADSWRDTETERGFSMALGRLGDPADSDCLLVEAIDPHNQVLAMLSLVPWGTTG 511 Query: 770 NTLSVDLMRNLPVKPNGTMDHLFVSLLKWAKEQGYAYFNLGMAPLSSVGQTQSAIREEKL 829 +S+DLMR P PNGT++ + L A+ G +L A + + + + + Sbjct: 512 --VSLDLMRRSPQSPNGTIELMVSELALHAESLGITRISLNFAVFRAAFEQGAQLGAGPV 569 Query: 830 AHL---VFKHGGHWYGFLGLRKYKEKFSPVWEPRYLAY 864 A L + W+ L + K+ P W PRY Y Sbjct: 570 ARLWRGLLVFFSRWWQLETLYRSNMKYQPEWVPRYACY 607 >lin1803_1 [S] COG0392 Predicted integral membrane protein Length = 252 Score = 69.3 bits (168), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 64/250 (25%), Positives = 112/250 (44%), Gaps = 20/250 (8%) Query: 25 LVQIIIPAAVILFIYWEGQKEFRRIDWAGTLHTLHHMKPATVLLLFGFALIAVATVSLYD 84 +V+I+ V+ F+ +E ID+ + P + ++F LIAV + LYD Sbjct: 18 IVKIVFITFVMGFVIFEIVNIATGIDYPSLKANITSQSPEQIFIMFIVGLIAVTPMLLYD 77 Query: 85 FVLRRHFQIPLSFWETFRYSWIANTSNSVIGFSGIAGAALRTFLYRKRKIPAQTITASIA 144 +V+ + S WI NT ++ GF G+ GA+LR Y K + I +I+ Sbjct: 78 YVIVKLLPGKFSPIHVVASGWITNTFTNIGGFGGVLGASLRASFYGKNA-SHKEILLAIS 136 Query: 145 FLSTITITGLSVLSWAGILGILPMQPVLQSH-----PWTIYAVWAAALYLPGYLILQRTS 199 ++ ++GLS+ + +L P H PW + A LY P ++ T Sbjct: 137 KIALFLVSGLSIYCLVSLTTLL--IPGFADHFVNYWPWLL----AGGLYFP--ILFTITK 188 Query: 200 FYAKWLNRNLPXXXXMDAATIAASVGASLLEWAFAGISFWLIGSCFLPALSLAQALGIYT 259 + +K L +LP + + ASLLEW FA F +IG + + + ++ Sbjct: 189 WKSKSLFVDLPIKRELTL------IVASLLEWGFAFGCFAIIGVLMGEPVDIFKVFPLFV 242 Query: 260 LSAITGLLSM 269 ++++ G+ SM Sbjct: 243 IASVIGIASM 252 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.325 0.140 0.440 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 62,558,803 Number of extensions: 2568642 Number of successful extensions: 6728 Number of sequences better than 1.0e-05: 4 Number of HSP's gapped: 6718 Number of HSP's successfully gapped: 4 Length of query: 888 Length of database: 38,378,431 Length adjustment: 115 Effective length of query: 773 Effective length of database: 25,115,021 Effective search space: 19413911233 Effective search space used: 19413911233 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 120 (50.8 bits)