BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0157.0020.p (619 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_yknV [V] COG1132 ABC-type multidrug transport system, ATPase ... 704 0.0 BH1126 [V] COG1132 ABC-type multidrug transport system, ATPase a... 699 0.0 lin0155 [V] COG1132 ABC-type multidrug transport system, ATPase ... 536 e-152 mll7116 [V] COG1132 ABC-type multidrug transport system, ATPase ... 418 e-116 TM0288 [V] COG1132 ABC-type multidrug transport system, ATPase a... 407 e-113 >BS_yknV [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 604 Score = 704 bits (1816), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/600 (56%), Positives = 455/600 (75%), Gaps = 5/600 (0%) Query: 18 AQEQSLEERFVYKDDDVIDKAFDWKQFTRLFSYMKPYARQMLPLVLVMMILGTVTKLTVP 77 A++Q + ERF Y D++I+K F+W Q RL SY+KPY + +LPL + +++GT KL +P Sbjct: 4 AKKQGVLERFYYSSDEIIEKPFNWAQMWRLLSYVKPYRKTILPLSFLTVLIGTAVKLVIP 63 Query: 78 YLTSM-AIDKAIAPKSGNPSLTLLYTLTAIVIVLYLIQWIAGVYRIKYTNVIGQRVIYDL 136 L + +D+AI ++ LL L I+ LY++ + A V RI++ N +GQ VIYDL Sbjct: 64 ILIGVYVLDQAITGRNSE----LLIQLIFIISGLYVLNYAANVLRIRWMNQLGQHVIYDL 119 Query: 137 RSDLFRHIQKLSFNFFDKRPAGSVLVRVTNDINSLQDLFTNGVVNLMIDCVQLLGIMVIL 196 R LF H+Q+LS FFD+R AGS+LVR+ NDINSLQ+LFT+GV+NL+ D + L G+++IL Sbjct: 120 RQHLFTHVQRLSHRFFDQRSAGSILVRIMNDINSLQELFTSGVINLLTDLLLLAGVIIIL 179 Query: 197 LLINWKLGLAVMITVPIMFFVSTKLRQKIRIAWQDVRMKNSRINSHLNESIQGIRVTQAY 256 ++ +L +A+M+T+PIMFF+ST LR+KIR +WQ VR+K S++NSHLNESIQGIRVTQA+ Sbjct: 180 FTLSPELTIAIMVTLPIMFFISTSLRKKIRRSWQTVRLKQSKLNSHLNESIQGIRVTQAF 239 Query: 257 TQEKENMNYFDAMNMDSRKSWNKASAMNQAFGPIIEITGGFGTMILFWFGAYLIQTGELT 316 TQE+ENM YFD +N ++ +SW +A+ N F P++E+T GT +L W+GA LI +T Sbjct: 240 TQEEENMAYFDGVNQENYESWREATRKNAMFRPLVEMTNAIGTAVLIWYGATLIMNETIT 299 Query: 317 VGFLVAFSSYVSNFWDPINRLGQMYNQLLVAMASSERIFEYLDEQPSVQDNPGATPLPKI 376 +G V+F+ Y+ FW+PI+RLGQ+YNQLL+ MASSERIFE+LDEQP+V++ P A KI Sbjct: 300 IGVFVSFAFYLGMFWEPISRLGQVYNQLLMGMASSERIFEFLDEQPNVKEKPNAIHNEKI 359 Query: 377 KGDIKFNKVVFEYEKGRAALKGIDLDVKAGQSIALVGHTGSGKSTIINLIGRFYDIKSGS 436 G+I F +V F Y++ R AL + + AG ++ALVGHTGSGK+TI NLI RFYD G+ Sbjct: 360 NGEISFEEVEFSYDEKRKALHAVSFSIPAGSTLALVGHTGSGKTTIANLISRFYDAAGGT 419 Query: 437 ITIDGQDTREVTLQSLREQIGIVLQDTFIFSGTIRDNIRFGRLDATDQEVEEAAKAVDAH 496 I IDG ++++L SLR QI IVLQDTFIFSGTI +NIRFGR +A+D+EV +A++AV A Sbjct: 420 IKIDGIPIKDLSLASLRSQISIVLQDTFIFSGTIMENIRFGRPNASDEEVMKASQAVGAD 479 Query: 497 EFISKLPGGYDTEVEERGSALSMGQRQLLSFARALLANPRILILDEATASIDTETEIKIQ 556 EFIS L GY TEVEERGS LS GQRQL+SFARALLA+P I+ILDEATASIDTETE+KIQ Sbjct: 480 EFISDLAEGYATEVEERGSVLSAGQRQLISFARALLADPAIIILDEATASIDTETEVKIQ 539 Query: 557 EALKILLQGRTSFIVAHRLSTIRHADKIVVLDHGEIKEEGTHAELTAHDGIYNGLIEAQF 616 +ALK LL+GRT+ ++AHRLSTIR AD+I+VLDHG EEG H +L A GIY GL++AQ+ Sbjct: 540 QALKTLLKGRTAVMIAHRLSTIRDADRIIVLDHGRKIEEGNHDQLLAKGGIYAGLVKAQY 599 >BH1126 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 601 Score = 699 bits (1805), Expect = 0.0, Method: Compositional matrix adjust. Identities = 345/592 (58%), Positives = 455/592 (76%), Gaps = 5/592 (0%) Query: 26 RFVYKDDDVIDKAFDWKQFTRLFSYMKPYARQMLPLVLVMMILGTVTKLTVPYLTS-MAI 84 RF Y D VI+K F+W Q RL +YMKPYA +LP +V M++ T +L VP + +AI Sbjct: 9 RFHYASDQVIEKPFNWAQMMRLLTYMKPYAASLLPKTVVAMLIVTAVRLFVPIIIGVLAI 68 Query: 85 DKAIAPKSGNPSLTLLYTLTAIVIVLYLIQWIAGVYRIKYTNVIGQRVIYDLRSDLFRHI 144 D AIA +G+ L ++Y L A+V+ LY I ++A V+RI++ N IGQ VIYD+R+DLF HI Sbjct: 69 DHAIA--AGD--LNVMYQLAALVLGLYSISYVANVFRIRWMNEIGQHVIYDIRADLFNHI 124 Query: 145 QKLSFNFFDKRPAGSVLVRVTNDINSLQDLFTNGVVNLMIDCVQLLGIMVILLLINWKLG 204 Q+LS FFD+R AGS+LVRV ND+NSLQDLFTNGV+NL++D V LLGI+VIL ++ +L Sbjct: 125 QRLSHRFFDQRSAGSILVRVVNDVNSLQDLFTNGVINLLMDIVILLGIIVILFSLSPELA 184 Query: 205 LAVMITVPIMFFVSTKLRQKIRIAWQDVRMKNSRINSHLNESIQGIRVTQAYTQEKENMN 264 + ++I +PIMFF+STKLR+ IR +WQ VR++ S++NSHLNESIQGIRVTQA++QEKENM Sbjct: 185 ILILIVLPIMFFISTKLRRNIRRSWQTVRLRQSKLNSHLNESIQGIRVTQAFSQEKENMR 244 Query: 265 YFDAMNMDSRKSWNKASAMNQAFGPIIEITGGFGTMILFWFGAYLIQTGELTVGFLVAFS 324 +F +N ++ +SW A+ MN F P +E+ G ++L W+G LIQ+ LTVG V+F+ Sbjct: 245 FFRDINEENFQSWKDATRMNALFRPFVEMASAIGAVVLIWYGVSLIQSEVLTVGVFVSFA 304 Query: 325 SYVSNFWDPINRLGQMYNQLLVAMASSERIFEYLDEQPSVQDNPGATPLPKIKGDIKFNK 384 Y+ FW+PI+RLGQ+YNQLLV MASSERIFE+LDE+PSV + A L +++G + F + Sbjct: 305 FYLGMFWEPISRLGQVYNQLLVGMASSERIFEFLDEKPSVPEKENAVTLHEMRGHVTFEQ 364 Query: 385 VVFEYEKGRAALKGIDLDVKAGQSIALVGHTGSGKSTIINLIGRFYDIKSGSITIDGQDT 444 V F Y+ R AL I ++KAGQ+IALVGHTGSGKSTI+NLI RFYD +G I IDG D Sbjct: 365 VEFSYDDKRKALNDISFEIKAGQTIALVGHTGSGKSTIVNLISRFYDPTAGVIKIDGVDL 424 Query: 445 REVTLQSLREQIGIVLQDTFIFSGTIRDNIRFGRLDATDQEVEEAAKAVDAHEFISKLPG 504 R++ L SLR + VLQDTFIF+GTI +NIRFGR ATD+EV+ AA+A+ A++FI +LP Sbjct: 425 RDIQLNSLRTNVSFVLQDTFIFAGTIMENIRFGRPTATDEEVKAAAEAIGANDFIERLPN 484 Query: 505 GYDTEVEERGSALSMGQRQLLSFARALLANPRILILDEATASIDTETEIKIQEALKILLQ 564 GYDTEVEE+G+ LS+G+RQLLSFARALLA+P+ILILDEATASIDTETE+KIQ LK LL Sbjct: 485 GYDTEVEEKGNVLSVGERQLLSFARALLADPKILILDEATASIDTETELKIQAGLKKLLH 544 Query: 565 GRTSFIVAHRLSTIRHADKIVVLDHGEIKEEGTHAELTAHDGIYNGLIEAQF 616 RT+ ++AHRLSTIR AD+I+VL+ G+I E+GTH+EL G Y GL++AQ+ Sbjct: 545 DRTAIMIAHRLSTIRDADQIIVLEQGDIIEQGTHSELMDARGTYYGLVKAQY 596 >lin0155 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 593 Score = 536 bits (1381), Expect = e-152, Method: Compositional matrix adjust. Identities = 268/590 (45%), Positives = 400/590 (67%), Gaps = 10/590 (1%) Query: 32 DDVIDKAFDWKQFTRLFSYMKPYARQMLPLVLVMMILGTVTKLTVPYLTSMAIDKAIAPK 91 D+ ++ AF R+ Y+KPY + + + L +++L V + PYLT + ID+ I Sbjct: 9 DEELETAFSAAHLKRILVYVKPYQKSIY-ITLFVILLANVATMIGPYLTKVVIDETIP-- 65 Query: 92 SGNPSLTLLYTLTAIVIVLYLIQWIAGVYRIKYTNVIGQRVIYDLRSDLFRHIQKLSFNF 151 N ++T L+ + I IV ++ + YRI+ +IGQ ++ D+R+ +F H+QKL F++ Sbjct: 66 --NKNMTQLFWIAVIFIVSVIVTGLCMRYRIRSITLIGQDILKDMRTAIFGHLQKLPFSY 123 Query: 152 FDKRPAGSVLVRVTNDINSLQDLFTNGVVNLMIDCVQLLGIMVILLLINWKLGLAVMITV 211 FD RP G +L+RV N IN L DL +NG++NL+ D + ++ + +L+I+ L L + + Sbjct: 124 FDSRPHGKILIRVVNYINMLSDLLSNGLINLISDILSVIVTLGFMLMIDPVLTLYSLALI 183 Query: 212 PIMFFVSTKLRQKIRIAWQDVRMKNSRINSHLNESIQGIRVTQAYTQEKENMNYFDAMNM 271 P++F + ++ R A+Q + K S +N++++ESI GI+VTQ++++E+EN F ++ Sbjct: 184 PVLFVIVMVIKTAQRKAYQVLSNKQSNMNAYIHESIAGIKVTQSFSREEENFEIFTEVSN 243 Query: 272 DSRKSWNKASAMNQAFGPIIEITGGFGTMILFWFG--AYLIQTGELTVGFLVAFSSYVSN 329 + R+SW KA + P ++ T ++++ G Y + +++ G L+AF YV N Sbjct: 244 EYRRSWMKAVKIQFLLWPGVQNIAVMTTCLIYFVGIKGYGV---DVSTGTLIAFIGYVGN 300 Query: 330 FWDPINRLGQMYNQLLVAMASSERIFEYLDEQPSVQDNPGATPLPKIKGDIKFNKVVFEY 389 FW+P+ +G YN L+ A ERIFE +D +P ++D P A +P I G++ F V F Y Sbjct: 301 FWNPVINIGNFYNSLITATTYLERIFETMDVEPDIKDVPNAKKMPPIVGNVDFKDVYFRY 360 Query: 390 EKGRAALKGIDLDVKAGQSIALVGHTGSGKSTIINLIGRFYDIKSGSITIDGQDTREVTL 449 E+G LKGI+ V AG+SIALVG TG+GK+TIINL+ RFY+I SG I +DG++ EVTL Sbjct: 361 EEGVDILKGINFHVDAGESIALVGPTGAGKTTIINLLSRFYNINSGEILVDGENVEEVTL 420 Query: 450 QSLREQIGIVLQDTFIFSGTIRDNIRFGRLDATDQEVEEAAKAVDAHEFISKLPGGYDTE 509 +SLR Q+G++LQDTFIFSGTI +NIR+G+LDAT++E+ AAK V AH+FIS L GY TE Sbjct: 421 RSLRSQMGVMLQDTFIFSGTIIENIRYGKLDATEEEIIAAAKVVRAHDFISGLKDGYYTE 480 Query: 510 VEERGSALSMGQRQLLSFARALLANPRILILDEATASIDTETEIKIQEALKILLQGRTSF 569 V+ERGS LS GQRQL+SFARALLA+P+ILILDEAT+SIDT+TEI +QE L+ LL+GRTSF Sbjct: 481 VKERGSTLSAGQRQLISFARALLADPKILILDEATSSIDTQTEILLQEGLERLLEGRTSF 540 Query: 570 IVAHRLSTIRHADKIVVLDHGEIKEEGTHAELTAHDGIYNGLIEAQFRFL 619 I+AHRLSTI+++ +I +D+G I+E G+H EL A G Y L ++QF L Sbjct: 541 IIAHRLSTIKNSSRIFYIDNGRIQEAGSHEELMAQHGYYYNLYQSQFDML 590 >mll7116 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 631 Score = 418 bits (1074), Expect = e-116, Method: Compositional matrix adjust. Identities = 223/582 (38%), Positives = 353/582 (60%), Gaps = 5/582 (0%) Query: 31 DDDVIDKAFDWKQFTRLFSYMKPYARQMLPLVLVMMILGTVTKLTVPYLTSMAIDKAIAP 90 +++V KA+D + R++S+++PY ++ V +++ T+T+L +P + AID +AP Sbjct: 28 EEEVFGKAYDPRIIRRIWSFVRPYQGRIFISVAAVLVF-TLTQLAIPLVIRYAIDHGMAP 86 Query: 91 KSGNPSLTLLYTLTAIVIVLYLIQWIAGVYRIKYTNVIGQRVIYDLRSDLFRHIQKLSFN 150 + S+ + +T VI+L I + A + + + V+ DLR +F H+Q +S + Sbjct: 87 GRLDRSVMISAIITFTVIIL--INYAASYVQESVVGKVAENVLSDLRRAMFSHLQLVSLS 144 Query: 151 FFDKRPAGSVLVRVTNDINSLQDLFTNGVVNLMIDCVQLLGIMVILLLINWKLGLAVMIT 210 F DK G ++ R+ D+NS+Q+ V+++ D V L GI+ +LL ++++LGL + T Sbjct: 145 FMDKTEVGRLMSRLQGDVNSMQEFLETSVMSVG-DIVLLFGIVTVLLWLDFRLGLLTLST 203 Query: 211 VPIMFFVSTKLRQKIRIAWQDVRMKNSRINSHLNESIQGIRVTQAYTQEKENMNYFDAMN 270 +P++F V + ++A+ NS N L E I G+R Q+ ++ N + +D Sbjct: 204 MPMLFIVRLFWLPRAKVAFMAAHETNSIANGALAEGIHGVRTVQSLERQHVNFDLYDEKV 263 Query: 271 MDSRKSWNKASAMNQAFGPIIEITGGFGTMILFWFGAYLIQTGELTVGFLVAFSSYVSNF 330 + + + +++ Q PI++ G + G ++ + L VG +VAF Y+ F Sbjct: 264 LANLNAHLRSARYAQVMVPIVDTLTGMAMATVIVVGGSMVLSHSLDVGVMVAFLFYIQRF 323 Query: 331 WDPINRLGQMYNQLLVAMASSERIFEYLDEQPSVQDNPGATPLPK-IKGDIKFNKVVFEY 389 +DPI L Y+ + AMAS +RI E LD V D A L + G ++F V F Y Sbjct: 324 FDPIRSLTMQYSVMQRAMASGQRISEVLDVPVDVSDKDNAVALSRETDGSVEFRNVTFGY 383 Query: 390 EKGRAALKGIDLDVKAGQSIALVGHTGSGKSTIINLIGRFYDIKSGSITIDGQDTREVTL 449 + LK I V G+++ALVG TGSGKS+ + L+ RFYD+ SG + + G D R++T Sbjct: 384 RPNQPVLKNISFRVNPGETVALVGPTGSGKSSSMALVHRFYDVWSGQVLVGGHDVRDLTQ 443 Query: 450 QSLREQIGIVLQDTFIFSGTIRDNIRFGRLDATDQEVEEAAKAVDAHEFISKLPGGYDTE 509 SL +Q+ +VLQ+ F+FSGT+ +NIR+ + A+ EV AA+AV AH+FI +LP GYDT+ Sbjct: 444 DSLGDQVAMVLQEPFLFSGTVLENIRYHKTGASRDEVVRAAQAVGAHDFIEQLPDGYDTQ 503 Query: 510 VEERGSALSMGQRQLLSFARALLANPRILILDEATASIDTETEIKIQEALKILLQGRTSF 569 +E+RG LS+GQRQL+SFARAL+A+ +IL+LDEATASID+ TE+ IQ+AL LL+GRT Sbjct: 504 LEQRGGNLSLGQRQLISFARALVADAKILVLDEATASIDSYTEMLIQKALIKLLEGRTGL 563 Query: 570 IVAHRLSTIRHADKIVVLDHGEIKEEGTHAELTAHDGIYNGL 611 ++AHRL+TIR AD+I+VL +GEI E G H +L G+Y L Sbjct: 564 VIAHRLATIRGADRIIVLQNGEIVESGNHEQLMQRKGLYARL 605 >TM0288 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 598 Score = 407 bits (1047), Expect = e-113, Method: Compositional matrix adjust. Identities = 213/571 (37%), Positives = 337/571 (59%), Gaps = 6/571 (1%) Query: 46 RLFSYMKPYARQMLPLVLVMMILGTVTKLTVPYLTSMAIDKAIAPKSGNPSLTLLYTLTA 105 RL Y++P+ ++ +V V + + ++ + PYL ID P+ + + L Sbjct: 27 RLLGYLRPHTFTLI-MVFVFVTVSSILGVLSPYLIGKTIDVVFVPRRFDLLPRYMLILGT 85 Query: 106 IVIVLYLIQWIAGVYRIKYTNVIGQRVIYDLRSDLFRHIQKLSFNFFDKRPAGSVLVRVT 165 I + L+ W+ G K + Q V++ LR +LF +Q++ FFD+ P G ++ RV Sbjct: 86 IYALTSLLFWLQG----KIMLTLSQDVVFRLRKELFEKLQRVPVGFFDRTPHGDIISRVI 141 Query: 166 NDINSLQDLFTNGVVNLMIDCVQLLGIMVILLLINWKLGLAVMITVPIMFFVSTKLRQKI 225 ND++++ ++ N ++ V L G ++++ +N L L + VP+ ++ + + Sbjct: 142 NDVDNINNVLGNSIIQFFSGIVTLAGAVIMMFRVNVILSLVTLSIVPLTVLITQIVSSQT 201 Query: 226 RIAWQDVRMKNSRINSHLNESIQGIRVTQAYTQEKENMNYFDAMNMDSRKSWNKASAMNQ 285 R + + + ++N + E I G+ V + +T+E++ M FD +N RK KA + Sbjct: 202 RKYFYENQRVLGQLNGIIEEDISGLTVIKLFTREEKEMEKFDRVNESLRKVGTKAQIFSG 261 Query: 286 AFGPIIEITGGFGTMILFWFGAYLIQTGELTVGFLVAFSSYVSNFWDPINRLGQMYNQLL 345 P++ + G ++ FG +L +TVG + F Y F P+N L +N + Sbjct: 262 VLPPLMNMVNNLGFALISGFGGWLALKDIITVGTIATFIGYSRQFTRPLNELSNQFNMIQ 321 Query: 346 VAMASSERIFEYLDEQPSVQDNPGATPLPKIKGDIKFNKVVFEYEKGRAALKGIDLDVKA 405 +A+AS+ERIFE LD + +D+P A L +++G+I+F V F Y+K + LK I +K Sbjct: 322 MALASAERIFEILDLEEE-KDDPDAVELREVRGEIEFKNVWFSYDKKKPVLKDITFHIKP 380 Query: 406 GQSIALVGHTGSGKSTIINLIGRFYDIKSGSITIDGQDTREVTLQSLREQIGIVLQDTFI 465 GQ +ALVG TGSGK+TI+NL+ RFYD+ G I +DG D R++ SLR IGIVLQDT + Sbjct: 381 GQKVALVGPTGSGKTTIVNLLMRFYDVDRGQILVDGIDIRKIKRSSLRSSIGIVLQDTIL 440 Query: 466 FSGTIRDNIRFGRLDATDQEVEEAAKAVDAHEFISKLPGGYDTEVEERGSALSMGQRQLL 525 FS T+++N+++G ATD+E++EAAK + FI LP GY+T + + G LS GQRQLL Sbjct: 441 FSTTVKENLKYGNPGATDEEIKEAAKLTHSDHFIKHLPEGYETVLTDNGEDLSQGQRQLL 500 Query: 526 SFARALLANPRILILDEATASIDTETEIKIQEALKILLQGRTSFIVAHRLSTIRHADKIV 585 + RA LANP+ILILDEAT+++DT+TE IQ A+ L++G+TS I+AHRL+TI++AD I+ Sbjct: 501 AITRAFLANPKILILDEATSNVDTKTEKSIQAAMWKLMEGKTSIIIAHRLNTIKNADLII 560 Query: 586 VLDHGEIKEEGTHAELTAHDGIYNGLIEAQF 616 VL GEI E G H EL G Y L +Q+ Sbjct: 561 VLRDGEIVEMGKHDELIQKRGFYYELFTSQY 591 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.322 0.137 0.391 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 43,050,820 Number of extensions: 1903894 Number of successful extensions: 29593 Number of sequences better than 1.0e-05: 1971 Number of HSP's gapped: 27107 Number of HSP's successfully gapped: 2107 Length of query: 619 Length of database: 38,378,431 Length adjustment: 112 Effective length of query: 507 Effective length of database: 25,461,023 Effective search space: 12908738661 Effective search space used: 12908738661 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 119 (50.4 bits)