BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0153.0033.p (446 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_tuaD [M] COG1004 Predicted UDP-glucose 6-dehydrogenase 453 e-127 BS_ywqF [M] COG1004 Predicted UDP-glucose 6-dehydrogenase 436 e-122 CC2379 [M] COG1004 Predicted UDP-glucose 6-dehydrogenase 402 e-112 CC2382 [M] COG1004 Predicted UDP-glucose 6-dehydrogenase 395 e-110 mlr5265 [M] COG1004 Predicted UDP-glucose 6-dehydrogenase 394 e-109 >BS_tuaD [M] COG1004 Predicted UDP-glucose 6-dehydrogenase Length = 461 Score = 453 bits (1165), Expect = e-127, Method: Compositional matrix adjust. Identities = 226/435 (51%), Positives = 307/435 (70%), Gaps = 3/435 (0%) Query: 2 KLAVIGTGYVGLVSGVCFTLNGNHVICVDKDEEKIKKLSQMESPIYEPGIEALIEMNLRE 61 K+AVIGTGYVGLVSG CF GN V+C D DE KI+ L PIYEPG+ L+E N+ + Sbjct: 3 KIAVIGTGYVGLVSGTCFAEIGNKVVCCDIDESKIRSLKNGVIPIYEPGLADLVEKNVLD 62 Query: 62 GRLSFSSDLHESVRRSDIVILAVGTPSLPGGEADLRYIEGAATEIAQAMEGYKIIMTKST 121 RL+F++D+ ++R SDI+ +AVGTP GEADL Y++ AA I + + GYK+I+ KST Sbjct: 63 QRLTFTNDIPSAIRASDIIYIAVGTPMSKTGEADLTYVKAAAKTIGEHLNGYKVIVNKST 122 Query: 122 VPVGTNEKIRKII--ASHTNHPFDIVSAPEFLREGSAIQDTLHPDRIVIGLDNPELEPAM 179 VPVGT + ++ I+ AS + FD+VS PEFLREGSAI DT++ +R VIG + + + Sbjct: 123 VPVGTGKLVQSIVQKASKGRYSFDVVSNPEFLREGSAIHDTMNMERAVIGSTSHKAAAII 182 Query: 180 RQLHQGFTENVFVTDIRSAEMIKYASNAFLATKISFINEIANICEKVGADVTEVAEGMGM 239 +LHQ F V T++ SAEMIKYA+NAFLATKISFIN+IANICE+VGADV++VA+G+G+ Sbjct: 183 EELHQPFHAPVIKTNLESAEMIKYAANAFLATKISFINDIANICERVGADVSKVADGVGL 242 Query: 240 DRRIGSTFLQAGIGYGGSCFPKDTNALIQIAGNVDYEFKLLKSVVEVNKDQRFMIISKLH 299 D RIG FL+AGIG+GGSCFPKDT AL+QIA + Y FKL+++V+E N+ QR I+ KL Sbjct: 243 DSRIGRKFLKAGIGFGGSCFPKDTTALLQIAKSAGYPFKLIEAVIETNEKQRVHIVDKLL 302 Query: 300 ESLGNLRGAVIGIWGLAFKPNTDDVREAPAREIVESLVAEGATVKLYDPIAAENFRQQYD 359 +G+++G I + GLAFKPNT+DVR APA +I+ L GA VK YDPIA Sbjct: 303 TVMGSVKGRTISVLGLAFKPNTNDVRSAPALDIIPMLQQLGAHVKAYDPIAIPEASAILG 362 Query: 360 HPQLRWCGLPEEAAEGSDAVCLLTDWSVFKDIDLHKLAESMRRQVLIDGRNVFSKEQIEG 419 Q+ + A E +DA +LTDW K+++L K+ +++ V+IDGRN+FS E+++ Sbjct: 363 E-QVEYYTDVYAAMEDTDACLILTDWPEVKEMELVKVKTLLKQPVIIDGRNLFSLEEMQA 421 Query: 420 TGFEYHSVGRPQMGG 434 G+ YHS+GRP + G Sbjct: 422 AGYIYHSIGRPAVRG 436 >BS_ywqF [M] COG1004 Predicted UDP-glucose 6-dehydrogenase Length = 440 Score = 436 bits (1120), Expect = e-122, Method: Compositional matrix adjust. Identities = 222/432 (51%), Positives = 296/432 (68%), Gaps = 5/432 (1%) Query: 1 MKLAVIGTGYVGLVSGVCFTLNGNHVICVDKDEEKIKKLSQMESPIYEPGIEALIEMNLR 60 M + VIGTGYVGLV+GV + G+HV C+D D KI ++ + SPI+EPG+E L+ N Sbjct: 1 MNITVIGTGYVGLVTGVSLSEIGHHVTCIDIDAHKIDEMRKGISPIFEPGLEELMRKNTA 60 Query: 61 EGRLSFSSDLHESVRRSDIVILAVGTPSLPGGEADLRYIEGAATEIAQAMEGYKIIMTKS 120 +GRL+F + + + ++DI+ +AVGTP G A+L I AA IA+ ++ +++TKS Sbjct: 61 DGRLNFETSYEKGLAQADIIFIAVGTPQKSDGHANLEQITDAAKRIAKHVKRDTVVVTKS 120 Query: 121 TVPVGTNEKIRKIIASHTNHPFDI--VSAPEFLREGSAIQDTLHPDRIVIGLDNPELEPA 178 TVPVGTN+ I +I H P I S PEFLREGSAI DT H DRIVIG + + Sbjct: 121 TVPVGTNDLINGLITEHLAEPVSISVASNPEFLREGSAIYDTFHGDRIVIGTADEKTANT 180 Query: 179 MRQLHQGFTENVFVTDIRSAEMIKYASNAFLATKISFINEIANICEKVGADVTEVAEGMG 238 + +L + F ++ TDIRSAEMIKYASNAFLATKISFINEI+NICEKVGAD+ VA GMG Sbjct: 181 LEELFRPFQIPIYQTDIRSAEMIKYASNAFLATKISFINEISNICEKVGADIEAVAYGMG 240 Query: 239 MDRRIGSTFLQAGIGYGGSCFPKDTNALIQIAGNVDYEFKLLKSVVEVNKDQRFMIISKL 298 D+RIGS FL+AGIGYGGSCFPKDTNAL+QIAGNV+++F+LLKSV++VN +Q+ M++ K Sbjct: 241 QDKRIGSQFLKAGIGYGGSCFPKDTNALVQIAGNVEHDFELLKSVIKVNNNQQAMLVDKA 300 Query: 299 HESLGNLRGAVIGIWGLAFKPNTDDVREAPAREIVESLVAEGATVKLYDPIAAENFRQQY 358 LG + G I + GL+FKPNTDD+REAP+ I + L A A ++ YDPIA + + Sbjct: 301 LNRLGGVTGKTIALLGLSFKPNTDDMREAPSIVIADRLAALDARIRAYDPIAVSHAKHVL 360 Query: 359 DHPQ-LRWCGLPEEAAEGSDAVCLLTDWSVFKDIDLHKLAESMRRQVLIDGRNVFSKEQI 417 PQ + + EEA +GSDAV +LTDW+ K L + M ++ DGRN ++ ++ Sbjct: 361 --PQAVEYKETIEEAVKGSDAVMILTDWADIKQFPLAAYQDLMETPLIFDGRNCYTLDEA 418 Query: 418 EGTGFEYHSVGR 429 G EY+SVGR Sbjct: 419 LAAGVEYYSVGR 430 >CC2379 [M] COG1004 Predicted UDP-glucose 6-dehydrogenase Length = 435 Score = 402 bits (1034), Expect = e-112, Method: Compositional matrix adjust. Identities = 202/436 (46%), Positives = 301/436 (69%), Gaps = 9/436 (2%) Query: 1 MKLAVIGTGYVGLVSGVCFTLNGNHVICVDKDEEKIKKLSQMESPIYEPGIEALIEMNLR 60 M++A+IGTGYVGLVSG CF G+ V C+DKD KI++L + E PI+EPG++ L+ N+R Sbjct: 1 MRVAMIGTGYVGLVSGACFADFGHVVTCIDKDPSKIERLERGEIPIFEPGLDDLVARNVR 60 Query: 61 EGRLSFSSDLHESVRRSDIVILAVGTPSLPG-GEADLRYIEGAATEIAQAMEGYKIIMTK 119 EGRL F+ + ++++ +D V +AVGTP+ G G ADL Y+ AA EIA ++G+ +++TK Sbjct: 61 EGRLFFTLEGAQAIKDADAVFIAVGTPTRRGDGHADLSYVYAAAEEIAGLIDGFTVVVTK 120 Query: 120 STVPVGTNEKIRKII-ASHTNHPFDIVSAPEFLREGSAIQDTLHPDRIVIGLDNPELEPA 178 STVPVGT +++ II ++ N F +VS PEFLREG+AI+D PDR+V+G D+ + Sbjct: 121 STVPVGTGDEVEAIIRKTNPNAQFAVVSNPEFLREGAAIEDFKRPDRVVVGTDDERAQAV 180 Query: 179 MRQLHQGFTEN---VFVTDIRSAEMIKYASNAFLATKISFINEIANICEKVGADVTEVAE 235 MR L++ + N + T R++E+IKYA+NAFLA KI+FINE+A++CEKVGADV VA+ Sbjct: 181 MRDLYRPLSLNETPIVFTGRRTSELIKYAANAFLAMKITFINEMADLCEKVGADVQSVAK 240 Query: 236 GMGMDRRIGSTFLQAGIGYGGSCFPKDTNALIQIAGNVDYEFKLLKSVVEVNKDQRFMII 295 G+G+D+RIG+ FL AG GYGGSCFPKDT AL++ A +L+++ VEVN ++ + Sbjct: 241 GIGLDKRIGAKFLNAGPGYGGSCFPKDTIALVKTAQQYGAPTRLIETTVEVNTARKKAMA 300 Query: 296 SKLHESLGN--LRGAVIGIWGLAFKPNTDDVREAPAREIVESLVAEGATVKLYDPIAAEN 353 K+ E++G L G IG+ G+ FKPNTDD+R+AP+ +I+ +L A GA V+ +DP A+ Sbjct: 301 EKVAEAMGTRELTGKTIGVLGVTFKPNTDDMRDAPSLDILPALQAMGAKVQAFDPEGAKE 360 Query: 354 FRQQYDHPQLRWCGLPEEAAEGSDAVCLLTDWSVFKDIDLHKLAESMRRQVLIDGRNVFS 413 + + +AAEG+DA+ +LT+W F+ +DL +L ++ V++D RNV+ Sbjct: 361 AAHMLAGVEFKSGAY--DAAEGADALVILTEWDQFRALDLDRLKSLLKTPVVVDLRNVYK 418 Query: 414 KEQIEGTGFEYHSVGR 429 ++E GF Y S+GR Sbjct: 419 PAEMERHGFTYASIGR 434 >CC2382 [M] COG1004 Predicted UDP-glucose 6-dehydrogenase Length = 435 Score = 395 bits (1015), Expect = e-110, Method: Compositional matrix adjust. Identities = 199/436 (45%), Positives = 297/436 (68%), Gaps = 9/436 (2%) Query: 1 MKLAVIGTGYVGLVSGVCFTLNGNHVICVDKDEEKIKKLSQMESPIYEPGIEALIEMNLR 60 M++A+IGTGYVGLVSG CF G+ V C+DKD KI++L + E PI+EPG++ L+ N+R Sbjct: 1 MRVAMIGTGYVGLVSGACFADFGHVVTCIDKDPSKIERLERGEIPIFEPGLDDLVARNVR 60 Query: 61 EGRLSFSSDLHESVRRSDIVILAVGTPSLPG-GEADLRYIEGAATEIAQAMEGYKIIMTK 119 EGRL F+ + ++++ +D V +AVGTP+ G G ADL Y+ AA EIA ++G+ +++TK Sbjct: 61 EGRLFFTLEGAQAIKDADAVFIAVGTPTRRGDGHADLSYVYAAAEEIAGLIDGFTVVVTK 120 Query: 120 STVPVGTNEKIRKIIAS-HTNHPFDIVSAPEFLREGSAIQDTLHPDRIVIGLDNPELEPA 178 STVPVGT +++ II + F +VS PEFLREG+AI+D PDR+V+G D+ + Sbjct: 121 STVPVGTGDEVEAIIRKVRPDAQFAVVSNPEFLREGAAIEDFKRPDRVVVGTDDERAQAV 180 Query: 179 MRQLHQGFTEN---VFVTDIRSAEMIKYASNAFLATKISFINEIANICEKVGADVTEVAE 235 MR L++ + N + T R++E+IKYA+NAFLA KI+FINE+A++CEKVGADV VA+ Sbjct: 181 MRDLYRPLSLNETPIVFTGRRTSELIKYAANAFLAMKITFINEMADLCEKVGADVQSVAK 240 Query: 236 GMGMDRRIGSTFLQAGIGYGGSCFPKDTNALIQIAGNVDYEFKLLKSVVEVNKDQRFMII 295 G+G+D+RIG+ FL AG GYGGSCFPKDT AL++ A +L+++ VEVN ++ + Sbjct: 241 GIGLDKRIGAKFLNAGPGYGGSCFPKDTIALVKTAQQYGAPTRLIETTVEVNTARKKAMA 300 Query: 296 SKLHESLGN--LRGAVIGIWGLAFKPNTDDVREAPAREIVESLVAEGATVKLYDPIAAEN 353 K+ E++G L G IG+ G+ FKPNTDD+R+AP+ +I+ +L GA V+ +DP A+ Sbjct: 301 EKVAEAMGTRELTGKTIGVLGVTFKPNTDDMRDAPSLDILPALQTMGAKVQAFDPEGAKE 360 Query: 354 FRQQYDHPQLRWCGLPEEAAEGSDAVCLLTDWSVFKDIDLHKLAESMRRQVLIDGRNVFS 413 + + +AAEG+DA+ +LT+W F+ +DL +L ++ V++D RNV+ Sbjct: 361 AAHMLAGVEFKAGAY--DAAEGADALVILTEWDQFRALDLDRLKSLLKAPVVVDLRNVYK 418 Query: 414 KEQIEGTGFEYHSVGR 429 ++ GF Y S+GR Sbjct: 419 PAEMVRHGFTYASIGR 434 >mlr5265 [M] COG1004 Predicted UDP-glucose 6-dehydrogenase Length = 443 Score = 394 bits (1012), Expect = e-109, Method: Compositional matrix adjust. Identities = 199/440 (45%), Positives = 281/440 (63%), Gaps = 11/440 (2%) Query: 1 MKLAVIGTGYVGLVSGVCFTLNGNHVICVDKDEEKIKKLSQMESPIYEPGIEALIEMNLR 60 M L V G GYVGLV G+ V+CVD DE K+++L+Q PI+EPG+E+L+ N Sbjct: 1 MNLTVFGIGYVGLVQAAVLAEVGHQVVCVDIDENKVERLNQGFVPIFEPGLESLVRENHA 60 Query: 61 EGRLSFSSDLHESVRRSDIVILAVGTPSLPGGEADLRYIEGAATEIAQAMEGYKIIMTKS 120 GR+ F++D +VR +I ++AVGTP G ADL+Y+ A I + M+ KI++ KS Sbjct: 61 AGRIKFTTDAAAAVRHGEIQMIAVGTPPGEDGSADLKYVLAVAETIGREMDTAKIVVGKS 120 Query: 121 TVPVGTNEKIRKIIAS------HTNHPFDIVSAPEFLREGSAIQDTLHPDRIVIGLDNPE 174 TVPVGT EK++ IA + FD+ S PEFL+EGSA+ D + PDRI++G + Sbjct: 121 TVPVGTCEKVKAKIAETLKKRGREDLSFDVASNPEFLKEGSAVADCMRPDRIIVGTSSEG 180 Query: 175 LEPAMRQLHQGFTEN---VFVTDIRSAEMIKYASNAFLATKISFINEIANICEKVGADVT 231 E MR+L+ F N + V D+RSAE KYA+N LATKISF+NE+AN+ E++GAD+ Sbjct: 181 TEAVMRELYAPFNRNHEKMIVMDVRSAEFTKYAANCMLATKISFMNEMANLAEQLGADIE 240 Query: 232 EVAEGMGMDRRIGSTFLQAGIGYGGSCFPKDTNALIQIAGNVDYEFKLLKSVVEVNKDQR 291 EV +G+G D RIG F+ G+GYGGSCFPKD ALI+ A V ++ KLL++V E N DQ+ Sbjct: 241 EVRKGIGSDPRIGYHFIYPGLGYGGSCFPKDVRALIKTAEGVKFDAKLLRAVEERNNDQK 300 Query: 292 FMIISKLHESL-GNLRGAVIGIWGLAFKPNTDDVREAPAREIVESLVAEGATVKLYDPIA 350 ++ K++ G+L+G +WGLAFKPNTDD+REAPAR ++E+L GATV+ YDP A Sbjct: 301 SVLFDKVNRYFKGSLKGKTFALWGLAFKPNTDDMREAPARVLMEALWKAGATVQAYDPEA 360 Query: 351 AENFRQQYD-HPQLRWCGLPEEAAEGSDAVCLLTDWSVFKDIDLHKLAESMRRQVLIDGR 409 + + Y L CG E A G+DA+ + T+W F+ L +++ V+ DGR Sbjct: 361 MQECQAIYGLRDDLLLCGTKEAALRGADALLIATEWKSFRAPSFDALKDALTTPVIFDGR 420 Query: 410 NVFSKEQIEGTGFEYHSVGR 429 N++ + + G EYHS+GR Sbjct: 421 NLYDPKVVARYGIEYHSIGR 440 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.136 0.393 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 33,776,887 Number of extensions: 1477861 Number of successful extensions: 3634 Number of sequences better than 1.0e-05: 25 Number of HSP's gapped: 3537 Number of HSP's successfully gapped: 25 Length of query: 446 Length of database: 38,378,431 Length adjustment: 110 Effective length of query: 336 Effective length of database: 25,691,691 Effective search space: 8632408176 Effective search space used: 8632408176 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 117 (49.7 bits)