BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0149.0025.p (314 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH0754 [T] COG0642 Signal transduction histidine kinase 160 3e-39 CAC0372 [T] COG0642 Signal transduction histidine kinase 126 4e-29 CAC0225 [T] COG0642 Signal transduction histidine kinase 122 6e-28 lin1852 [T] COG0642 Signal transduction histidine kinase 112 1e-24 BH0272 [T] COG0642 Signal transduction histidine kinase 99 7e-21 >BH0754 [T] COG0642 Signal transduction histidine kinase Length = 353 Score = 160 bits (404), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 92/236 (38%), Positives = 130/236 (55%), Gaps = 21/236 (8%) Query: 77 FQKIENNPVSKALEQLLHTQYRHYQQQLTAVKL--------------QQEQH---LTFID 119 FQ++ + +LE LL + +QL +KL QEQH F + Sbjct: 70 FQELRQAKENVSLESLLKVKEGITNEQLAMIKLFGQAFEDYSTRLHTAQEQHSRSYHFAN 129 Query: 120 QWVHQMKTPLSVIELTVQNMDEPE----FASIREELERMRGGLHTVLYMARLRAFEKDFH 175 +W HQMKTPLSVI L +Q DE I EE+ ++ GLH +L RL+ FE DF Sbjct: 130 RWTHQMKTPLSVIRLILQEQDEWSKEVLVDQIEEEVGKLEDGLHMMLSTVRLQKFELDFS 189 Query: 176 IKPVVLPKLIGEVVHDHKRLFIRNRIFPEVKAASPGITAQTDEKWLFFMLSQIINNAIKY 235 I+ + L +I V+H ++ FIR RI+P + + + + A TD+KWL F+L Q+I NA+KY Sbjct: 190 IERIALLSVIRSVLHGKRKTFIRYRIYPRLISEAEEVFAATDKKWLIFVLEQLIQNALKY 249 Query: 236 SAAKNTGGGQKITVSCYLRGPDAVIEVKDQGIGIQKSDLKRVFDPFFTGDNGRGLR 291 S+ + ITV + ++D+GIGI DL RVFDPFFTG+NGR L+ Sbjct: 250 SSTLAREPSKYITVRVEETDNGVTVSIQDEGIGIVAEDLPRVFDPFFTGENGRKLQ 305 >CAC0372 [T] COG0642 Signal transduction histidine kinase Length = 334 Score = 126 bits (317), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 69/211 (32%), Positives = 114/211 (54%), Gaps = 7/211 (3%) Query: 84 PVSKALEQLLHTQYRHYQQQLTAVKLQQEQHLTFIDQWVHQMKTPLSVIELTVQNMDEP- 142 P + ++ + +++Y +++ + + FI QW+H MKTP+SVI+L VQ E Sbjct: 85 PEQRMAQEAILKIHKNYAAKISEIDYKNSDIKYFISQWIHNMKTPVSVIDLIVQREKEKL 144 Query: 143 ---EFASIREELERMRGGLHTVLYMARLRAFEKDFHIKPVVLPKLIGEVVHDHKRLFIRN 199 +I EE +++ G+ VL + RL F +D+ + V + +L+ ++ K FI Sbjct: 145 SGDVIKNIEEENYKIKNGMDQVLNIIRLDEFSRDYEPEIVDIVELVKRTINLKKNQFIYG 204 Query: 200 RIFPEVKAASPGITAQTDEKWLFFMLSQIINNAIKYSAAKNTGGGQKITVSCYLRGPDAV 259 FP+V+ TD+KW F++ QII+N+IKYS + G + + Sbjct: 205 NAFPKVEFHVDKALVLTDKKWSTFIIDQIISNSIKYSKKEEKG---YVYFNIVQSNNKTH 261 Query: 260 IEVKDQGIGIQKSDLKRVFDPFFTGDNGRGL 290 + +KD G+GI K DLKR+F+PFFTG+NGR Sbjct: 262 LVIKDNGVGIPKYDLKRIFEPFFTGENGRNF 292 >CAC0225 [T] COG0642 Signal transduction histidine kinase Length = 339 Score = 122 bits (306), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 72/220 (32%), Positives = 123/220 (55%), Gaps = 19/220 (8%) Query: 69 PLETLDESFQKIENNPVSKALEQLLHTQYRHYQQQLTAVKLQQEQHLTFIDQWVHQMKTP 128 PLE DE + I +E L Y+ Y +++ +++ + E + F+ W+H++KTP Sbjct: 86 PLEYKDEVYISI--------IEDL----YKDYNERIVSLEKEFEDNNEFMTAWIHEIKTP 133 Query: 129 LSVIELTVQNMDEPEFASIREELERMRGGLHTVLYMARLRAFEKDFHIKPVVLPKLIGEV 188 ++ +L +++ E + EE+E++ + VLY +R F KD+ I V + KLI E Sbjct: 134 IATAKLLLES-GEIDSQLFMEEIEKIDDYVEKVLYYSRSDNFSKDYIISEVNISKLIKEC 192 Query: 189 VHDHKRLFIRNRIFPEVKAASPGITAQTDEKWLFFMLSQIINNAIKYSAAKNTGGGQKIT 248 + H ++FI+ I +++ +TD+KW F+L+QII+NA+KY+ N G I Sbjct: 193 IKSHSKIFIKKHIKLKLEI-DERFNVETDKKWFLFILNQIISNALKYT---NDMGN--II 246 Query: 249 VSCYLRGPDAVIEVKDQGIGIQKSDLKRVFDPFFTGDNGR 288 + + + V+ ++D GIGI+K DL R+F FTG NGR Sbjct: 247 IKAFEDDNEKVVIIEDNGIGIKKEDLDRIFSKSFTGYNGR 286 >lin1852 [T] COG0642 Signal transduction histidine kinase Length = 182 Score = 112 bits (279), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 0/218 (0%), Positives = 0/218 (0%), Gaps = 15/218 (6%) Query: 80 IENNPVSKALEQLLHTQY---RHYQQQLTAVKLQ--QEQHLTFIDQWVHQMKTPLSVIEL 134 + + V+ + + Sbjct: 83 RCRYELGVEITPPESIYPDFRYRATDPSGIVENEVCPVFAARTTSALQINDDEVMDYQWC 142 Query: 135 TVQNMDEPE----FASIREELERMRGGLHTVLYMARLRAFEKDFHIKPVVLPKLIGEVVH 190 + ++ Sbjct: 143 DLADVLHGIDATP 202 Query: 191 DHKRLFIRNRIFPEVKAASPGITAQTDEKWLFFMLSQIINNAIKYSAAKNTGGGQKITVS 250 Sbjct: 203 ----- 257 Query: 251 CYLRGPDAVIEVKDQGIGIQKSDLKRVFDPFFTGDNGR 288 Sbjct: 258 - 294 >BH0272 [T] COG0642 Signal transduction histidine kinase Length = 331 Score = 99.4 bits (246), Expect = 7e-21, Method: Compositional matrix adjust. Identities = 88/298 (29%), Positives = 141/298 (47%), Gaps = 25/298 (8%) Query: 1 MKLFIREHALLLAVQMVQFGAM-LSIYWFDGYRNLPTALYSVFIGFFFLSCXXXXXXXXX 59 MKLFI++H + + ++ F + I DG+ N Y F+ L Sbjct: 1 MKLFIKDHLSFILLYLITFICLPFIIEQLDGFENHYD--YFSFLAITLLMSLLVIRYLRR 58 Query: 60 XXXXXXXXXPLETLDESFQKI--ENNPVSKAL-EQLLHTQYRHYQQQLTAVKLQQEQHLT 116 E LD++ I + P+ KA QL ++Q T QEQ L Sbjct: 59 KKMYTHLKK--ENLDQADFLIYRPHAPIEKAYANQLKEFSSLLLKEQDTYQNFLQEQQL- 115 Query: 117 FIDQWVHQMKTPLSVIELTVQNMDEP------EFASIREELERMRGGLHTVLYMARLRAF 170 I VHQMKTP+SV++L VQ+ E+ ++ E +++ L+ +L +R Sbjct: 116 LISHAVHQMKTPISVMQLLVQSNQTNDVKSLGEWQKVKAECDKIYFSLNQLLSYSRSTQL 175 Query: 171 EKDFHIKPVVLPKLIGEVVHDHKRLFIRNRIFPEVKAASPGITAQTDEKWLFFMLSQIIN 230 D I+ + L K+I EV++D K FI +FP+V A I +D KW+ ++ Q+++ Sbjct: 176 LSDLKIEAMPLKKIIQEVINDLKDYFIEEELFPKVTIAEEVILY-SDRKWMKVVVYQLLS 234 Query: 231 NAIKYSAAKNTGGGQKITVSCYLRGPDAVIEVKDQGIGIQKSDLKRVFDPFFTGDNGR 288 NAIKY G + TV Y R + + + ++G I KS++ R+F+ F+TG GR Sbjct: 235 NAIKY-------GEKHSTVHIYYR--NGQLSIHNRGETIPKSEINRLFNLFYTGSKGR 283 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.324 0.140 0.416 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 21,597,823 Number of extensions: 826608 Number of successful extensions: 3717 Number of sequences better than 1.0e-05: 59 Number of HSP's gapped: 3720 Number of HSP's successfully gapped: 59 Length of query: 314 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 208 Effective length of database: 26,153,027 Effective search space: 5439829616 Effective search space used: 5439829616 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 116 (49.3 bits)