BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0145.0003.p (336 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SP1725 [K] COG1609 Transcriptional regulators 256 4e-68 SPy1817 [K] COG1609 Transcriptional regulators 224 1e-58 SP1799 [K] COG1609 Transcriptional regulators 214 2e-55 BS_rbsR [K] COG1609 Transcriptional regulators 206 4e-53 BH1250 [K] COG1609 Transcriptional regulators 180 3e-45 >SP1725 [K] COG1609 Transcriptional regulators Length = 321 Score = 256 bits (653), Expect = 4e-68, Method: Compositional matrix adjust. Identities = 136/323 (42%), Positives = 195/323 (60%), Gaps = 9/323 (2%) Query: 15 IKDVALKAGVSATTVSRVLNNRGYLSEALKQRVYSAMEELNYRPNELARSLSRSRSNIIG 74 + DVA AGVS TTVSRV+N +GYLSE Q+V AM EL Y+PN LARSL + +IG Sbjct: 5 LTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMRELGYKPNNLARSLQGKSAKLIG 64 Query: 75 LIIPLVSLPFFSELTSYIEEHAYLNGYKLLLCNSQQDKIKELEYIDMLRSSRVDGIIMGS 134 LI P +S F++EL +E + NGYK ++CNS+ D KE EYI+ML +++VDGII GS Sbjct: 65 LIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDSEKEREYIEMLEANQVDGIISGS 124 Query: 135 HTLEVEAYRQMNLPLVTFDRQISPGIPFVCSDNYTGGQLATTLLIEKGCRKLAHIGGHPE 194 H L +E Y ++ P+++FDR +SP IP V SDNY GG LA L++ G + + I G+ Sbjct: 125 HNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAGGVLAAQTLVKTGAQSIIMITGNDN 184 Query: 195 LNLLSNLRYEAFVETARLAGIWHTSLHTDNNSFDVLAYERLLEQLF-REHSGIDGIFAGS 253 N + LR+ F A I + S + F + E ++ + RE D IFA Sbjct: 185 SNSPTGLRHAGFASVLPKAPIINVS-----SDFSPVRKEMEIKNILTREKP--DAIFASD 237 Query: 254 DLIAAFALKACRERGRRVPADVRIVGYDGTALCSLNHPSITTIRQPMEEMGRLAVELILK 313 DL A +K +E G VP +++++GYDGT +P + TI+QP+EE+ L ++L+L+ Sbjct: 238 DLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQLATIKQPLEEIACLTIDLLLQ 297 Query: 314 QVEGMSVPSAN-ILPVKLQEGST 335 ++EG V + LPV L G + Sbjct: 298 KIEGKEVATTGYFLPVTLLPGKS 320 >SPy1817 [K] COG1609 Transcriptional regulators Length = 321 Score = 224 bits (572), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 121/322 (37%), Positives = 190/322 (59%), Gaps = 7/322 (2%) Query: 15 IKDVALKAGVSATTVSRVLNNRGYLSEALKQRVYSAMEELNYRPNELARSLSRSRSNIIG 74 + DVA AGVS TTVSRV+N +GYLS+ +V AM EL Y+PN LARSL + +IG Sbjct: 5 LTDVAALAGVSPTTVSRVINKKGYLSQKTVNKVNKAMRELGYKPNNLARSLQGKSTQLIG 64 Query: 75 LIIPLVSLPFFSELTSYIEEHAYLNGYKLLLCNSQQDKIKELEYIDMLRSSRVDGIIMGS 134 LI P +S F++EL ++E + GYK ++CNS+ + +KE EY++ML +++VDGII S Sbjct: 65 LIFPNISNIFYAELIEHLEIELFKQGYKTIICNSEHNPVKEREYLEMLAANQVDGIISSS 124 Query: 135 HTLEVEAYRQMNLPLVTFDRQISPGIPFVCSDNYTGGQLATTLLIEKGCRKLAHIGGHPE 194 H L +E Y ++ P+V FDR ++P IP + SDN+ GG+LA L + GC+ + I G+ Sbjct: 125 HNLGIEDYERVEAPIVAFDRNLAPNIPVISSDNFEGGKLAAQTLQKHGCQNIVMITGNDN 184 Query: 195 LNLLSNLRYEAF-VETARLAGIWHTSLHTDNNSFDVLAYERLLEQLFREHSGIDGIFAGS 253 + + LR F + R A I N+ + E ++ + DG+F Sbjct: 185 SDSPTGLRQLGFNYQLKRSAEIIKLP-----NNLSPVRREMEIKSILATRKP-DGLFVSD 238 Query: 254 DLIAAFALKACRERGRRVPADVRIVGYDGTALCSLNHPSITTIRQPMEEMGRLAVELILK 313 DL A +K ++ +P D++++GYDGT P + TIRQP++E+ +L+VE+++K Sbjct: 239 DLTAILIMKVAKQLHITIPEDMKVIGYDGTTFIQQYVPQLATIRQPIDEIAKLSVEILIK 298 Query: 314 QVEGMSVPSANILPVKLQEGST 335 +++ ILP+ L G++ Sbjct: 299 KIKKEKTSKDYILPITLLPGAS 320 >SP1799 [K] COG1609 Transcriptional regulators Length = 333 Score = 214 bits (544), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 124/327 (37%), Positives = 185/327 (56%), Gaps = 12/327 (3%) Query: 14 TIKDVALKAGVSATTVSRVLNNRGYLSEALKQRVYSAMEELNYRPNELARSLSRSRSNII 73 T+KDVAL+AGVS TVSRV+N + E ++V A++ LNY P+ AR + ++R+ I Sbjct: 9 TMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQAIKTLNYIPDYYARGMKKNRTETI 68 Query: 74 GLIIPLVSLPFFSELTSYIEEHAYLNGYKLLLCNSQQDKIKELEYIDMLRSSRVDGIIMG 133 +I+P + PFFSE ++E Y KLLLC S +E +Y++MLR ++VDG++ Sbjct: 69 AIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLC-SINGTNREQDYLEMLRHNKVDGVVAI 127 Query: 134 SHTLEVEAYRQMNLPLVTFDRQISP-GIPFVCSDNYTGGQLATTLLIEKGCRKLAHIGGH 192 +++ +E Y +P V+ DR S IP V SDN GG+ A LI KGC+ LA +GGH Sbjct: 128 TYS-PIEHYLTSGIPFVSIDRTYSDIAIPCVSSDNDAGGREAAKQLISKGCQHLAFVGGH 186 Query: 193 -PELNLLSNLR--YEAFVETARLAGIWHTSLHTDNNSFDVLAYERLLEQLFREHSGIDGI 249 +N R +E +V+ ++ L + V Y LE E+S IDGI Sbjct: 187 NTTINETKRRRISFEKYVQEHKIP------LSIFDLDETVTDYYGKLESFLEENSSIDGI 240 Query: 250 FAGSDLIAAFALKACRERGRRVPADVRIVGYDGTALCSLNHPSITTIRQPMEEMGRLAVE 309 F +D A ++ + G+R+P DV+I+GYDG + ++TI QP+EEM + AV Sbjct: 241 FTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKMAGDRDYLLSTIEQPLEEMAKEAVR 300 Query: 310 LILKQVEGMSVPSANILPVKLQEGSTT 336 ++ ++G +V ILPVK EG TT Sbjct: 301 ILFDIIDGKTVNLQTILPVKFVEGKTT 327 >BS_rbsR [K] COG1609 Transcriptional regulators Length = 330 Score = 206 bits (524), Expect = 4e-53, Method: Compositional matrix adjust. Identities = 58/301 (19%), Positives = 107/301 (35%), Gaps = 4/301 (1%) Query: 12 MPTIKDVALKAGVSATTVSRVLNNRGYLSEALKQRVYSAMEELNYRPNELARSLSRSRSN 71 M T+KDVA AGVS +TVS V+N ++SEA+ +V +A++ELNY P+ LARSL ++++ Sbjct: 1 MATMKDVARLAGVSTSTVSHVINKDRFVSEAITAKVEAAIKELNYAPSALARSLKLNQTH 60 Query: 72 IIGLIIPLVSLPFFSELTSYIEEHAYLNGYKLLLCNSQQDKIKELEYIDMLRSSRVDGII 131 IG++I + PF+SEL +E + GY L+LCN++ D+ + ++ L RVDG++ Sbjct: 61 TIGMLITASTNPFYSELVRGVERSCFERGYSLVLCNTEGDEQRMNRNLETLMQKRVDGLL 120 Query: 132 MGSHTLEVEAYRQMNLPLVTFDRQISPGIPFVCSDNYTGGQLATTLLIEKGCRKLAHIGG 191 + + M + PF + + Sbjct: 121 LLCTETHQPSREIMQRYPTVPTVMMD-WAPFDGDSDLIQDNSLLGGDLATQYLIDKGHTR 179 Query: 192 HPELNLLSNLRYEAFVETARLAGIWHTSLHTDNNSFDVLAYERLLEQLFREHSGIDGIFA 251 + + + A + + + Sbjct: 180 IACITGPLD-KTPARLRLEGYRAAMKRAGLN--IPDGYEVTGDFEFNGGFDAMRQLLSHP 236 Query: 252 GSDLIAAFALKACRERGRRVPADVRIVGYDGTALCSLNHPSITTIRQPMEEMGRLAVELI 311 A + + A+ + + + P + + Sbjct: 237 LRPQAVFTGNDAMAVGVYQALYQAELQVPQDIAVIGYDDIELASFMTPPLTTIHQPKDEL 296 Query: 312 L 312 Sbjct: 297 G 297 >BH1250 [K] COG1609 Transcriptional regulators Length = 338 Score = 180 bits (456), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 114/307 (37%), Positives = 174/307 (56%), Gaps = 8/307 (2%) Query: 12 MPTIKDVALKAGVSATTVSRVLNNRGYLSEALKQRVYSAMEELNYRPNELARSLSRSRSN 71 M TIK+VA AG+S TTVSRV+NN Y+S+ +Q+V AM++L Y PN A+ L R+++ Sbjct: 1 MATIKEVAQLAGLSRTTVSRVINNHPYVSDEKRQQVLDAMKQLGYVPNSSAQRLRRNKTE 60 Query: 72 IIGLIIPLVSLPFFSELTSYIEEHAYLNGYKLLLCNSQQDKIKELEYIDMLRSSRVDGII 131 I ++I + PFFS L +E A +GY+L+LCN++Q K KEL Y+++LR+ +VDGII Sbjct: 61 TIAVVISRIVNPFFSGLVDEMERVASEHGYQLILCNTRQSKEKELSYLELLRTKQVDGII 120 Query: 132 MGSHTLEVEAYRQMNL--PLVTFDRQISPG--IPFVCSDNYTGGQLATTLLIEKGCRKLA 187 M S E E P+V + + PG IP V + G +AT L+E G RK+A Sbjct: 121 MASMQNEWEVIEPYTAYGPMVACN-EYRPGMSIPLVRLNQEEAGYVATKHLLELGHRKIA 179 Query: 188 HIGGHPELNLLSNLRYEAFVETARLAGIWHTSLHTDNNSFDVLAYERL--LEQLFREHSG 245 + G+ + LS R ++ + GI T ++F + +R L Q ++ Sbjct: 180 CLAGNKAIP-LSEDRKAGYLRALQEYGIKVKEEWTYYHAFSIDDGKRWFRLFQTIETNTR 238 Query: 246 IDGIFAGSDLIAAFALKACRERGRRVPADVRIVGYDGTALCSLNHPSITTIRQPMEEMGR 305 +F GSD +AA L + G +P D+ IVG+D + +L P +TTI QP+ +GR Sbjct: 239 PTAVFTGSDEVAAGILSEAKVHGWNIPKDLAIVGFDNQQIATLVTPRLTTIEQPISLIGR 298 Query: 306 LAVELIL 312 A+E++ Sbjct: 299 RALEVMF 305 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.320 0.136 0.387 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 23,767,529 Number of extensions: 967031 Number of successful extensions: 2579 Number of sequences better than 1.0e-05: 186 Number of HSP's gapped: 2316 Number of HSP's successfully gapped: 188 Length of query: 336 Length of database: 38,378,431 Length adjustment: 107 Effective length of query: 229 Effective length of database: 26,037,693 Effective search space: 5962631697 Effective search space used: 5962631697 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 116 (49.3 bits)