BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0128.0034.p (400 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH1695 [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase 307 2e-83 BS_aspB [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase 305 1e-82 CC1534 [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase 295 9e-80 CAC1819 [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase 295 1e-79 aq_1969 [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase 290 3e-78 >BH1695 [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase Length = 395 Score = 307 bits (786), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 155/389 (39%), Positives = 230/389 (59%), Gaps = 11/389 (2%) Query: 6 IQLADWVERVQPSPTALLESTVARYQREGRTVYRLGLGQPDFPTPDRAKAAAIQAIQDNF 65 ++LA V + PS T + + + +G V LG G+PDF TP AA++++++ Sbjct: 1 MELAKRVSTLTPSSTLAITAKAKELKEQGHDVIGLGAGEPDFNTPQYIIDAAVRSMEEGH 60 Query: 66 TGYTDTGGILPLREAICRALLRDMGLSYDPGDIVVTVGGKHALFNAICTLCRPGDEVLIP 125 T YT +GG+ L+EAI +D GL+Y +I V G KH L+ L GDEV+IP Sbjct: 61 TKYTPSGGLPKLKEAIIEKFKQDQGLTYTAKEIFVGTGAKHVLYTLFQALLNEGDEVIIP 120 Query: 126 IPYWVSFPEQVKFAGAKPVFVQTVASSGYKVTPETLTPWVNESTRLLILNQPNNPSGAVY 185 PYWVS+PEQVK AG +PVFV+ S+ +K+TP L P + + T+ +I+N P+NP+G++Y Sbjct: 121 SPYWVSYPEQVKLAGGEPVFVEGKESNDFKLTPAQLEPVLTDRTKAIIINSPSNPTGSLY 180 Query: 186 SAAELAKLAEFCRQRDLWVISDEVYSAFVFKPEGYTSIASF-PGMRERTVVINAVSKSYG 244 + ELA L E C + ++ +ISDE+Y V+ +TS+A P ++E TVVIN VSKS+ Sbjct: 181 TQEELAALGEVCLKHNVLIISDEIYEKLVYDGAKHTSVAEISPQLKENTVVINGVSKSHS 240 Query: 245 MTGWRIGYSAAPAAVTGAMLRLQSHTTSNPXXXXXXXXXXXXDGPQDDLEDIRGEYATRR 304 MTGWRIGY+A P A+ AM L SH+TSNP +E +R + R Sbjct: 241 MTGWRIGYAAGPEALIQAMTNLASHSTSNPTTSAQYGAIAAYTEDDGSVEKMRVAFEERL 300 Query: 305 SVLVEGVRRIKGLECSVPDGAFYVW---VDASAWRGQTLEGQTISTADDLADILLKKAGV 361 + + + I G+ C P GAFY++ +A+A G T DD +LL++ V Sbjct: 301 HTIYDKLVAIPGVSCVKPKGAFYLFPNVEEAAALTGH-------ETVDDFVKVLLEEEKV 353 Query: 362 AVMPGTGFGSPYHIRLSYAVSRDEMESGI 390 A++PG+GFG+P ++RLSYA S + +E+ I Sbjct: 354 ALVPGSGFGAPDNVRLSYATSLELLEAAI 382 >BS_aspB [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase Length = 393 Score = 305 bits (780), Expect = 1e-82, Method: Compositional matrix adjust. Identities = 145/386 (37%), Positives = 223/386 (57%), Gaps = 5/386 (1%) Query: 6 IQLADWVERVQPSPTALLESTVARYQREGRTVYRLGLGQPDFPTPDRAKAAAIQAIQDNF 65 ++LA V + PS T + + + G V LG G+PDF TP AA++++ + Sbjct: 1 MKLAKRVSALTPSTTLAITAKAKELKAAGHDVIGLGAGEPDFNTPQHIIDAAVRSMNEGH 60 Query: 66 TGYTDTGGILPLREAICRALLRDMGLSYDPGDIVVTVGGKHALFNAICTLCRPGDEVLIP 125 T YT +GG+ L+ +I RD + Y P I+V G KHAL+ + DEV+IP Sbjct: 61 TKYTPSGGLAELKNSIAEKFKRDQNIEYKPSQIIVCTGAKHALYTLFQVILDEEDEVIIP 120 Query: 126 IPYWVSFPEQVKFAGAKPVFVQTVASSGYKVTPETLTPWVNESTRLLILNQPNNPSGAVY 185 PYWVS+PEQVK AG KPV+V+ + + +K++PE L + E T+ +++N P+NP+G +Y Sbjct: 121 TPYWVSYPEQVKLAGGKPVYVEGLEENHFKISPEQLKNAITEKTKAIVINSPSNPTGVMY 180 Query: 186 SAAELAKLAEFCRQRDLWVISDEVYSAFVFKPEGYTSIASFPG-MRERTVVINAVSKSYG 244 + EL+ L E C + D+ ++SDE+Y + + + SIA ++E+TV+IN VSKS+ Sbjct: 181 TEEELSALGEVCLEHDILIVSDEIYEKLTYGGKKHVSIAQLSDRLKEQTVIINGVSKSHS 240 Query: 245 MTGWRIGYSAAPAAVTGAMLRLQSHTTSNPXXXXXXXXXXXXDGPQDDLEDIRGEYATRR 304 MTGWRIGY+A + AM L SH+TSNP +GP + LE++R + R Sbjct: 241 MTGWRIGYAAGSEDIIKAMTNLASHSTSNPTSIAQYGAIAAYNGPSEPLEEMREAFEHRL 300 Query: 305 SVLVEGVRRIKGLECSVPDGAFYVWVDASAWRGQTLEGQTISTADDLADILLKKAGVAVM 364 + + + I G C P+GAFY++ +A + + D+ LL++ VA++ Sbjct: 301 NTIYAKLIEIPGFSCVKPEGAFYLFPNAK----EAAQSCGFKDVDEFVKALLEEEKVAIV 356 Query: 365 PGTGFGSPYHIRLSYAVSRDEMESGI 390 PG+GFGSP ++RLSYA S D +E I Sbjct: 357 PGSGFGSPENVRLSYATSLDLLEEAI 382 >CC1534 [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase Length = 400 Score = 295 bits (755), Expect = 9e-80, Method: Compositional matrix adjust. Identities = 157/391 (40%), Positives = 221/391 (56%), Gaps = 3/391 (0%) Query: 12 VERVQPSPTALLESTVARYQREGRTVYRLGLGQPDFPTPDRAKAAAIQAIQDNFTGYTDT 71 + R+ PS T + + + GR V L G+PDF TPD K AAI+AI+ T YTD Sbjct: 8 LRRIAPSATIAISAKARALKAAGRDVIALSAGEPDFDTPDNIKNAAIEAIKAGKTKYTDP 67 Query: 72 GGILPLREAICRALLRDMGLSYDPGDIVVTVGGKHALFNAICTLCRPGDEVLIPIPYWVS 131 G+ L+ AIC R+ GL Y P I V GGK ++NA+ PGDEV+IP PYWVS Sbjct: 68 DGMPELKAAICAKFKRENGLEYKPSQIHVAPGGKPVIYNALVATLNPGDEVIIPAPYWVS 127 Query: 132 FPEQVKFAGAKPVFVQTVASSGYKVTPETLTPWVNESTRLLILNQPNNPSGAVYSAAELA 191 +P+ AG PV V+T A SG+K+TPE L + T+ LI+N P+NPSG YS AEL Sbjct: 128 YPDMTLLAGGTPVSVETTAESGFKITPEALEAAITPKTKWLIINSPSNPSGGAYSRAELQ 187 Query: 192 KLAE-FCRQRDLWVISDEVYSAFVFKPEGYTSIASF-PGMRERTVVINAVSKSYGMTGWR 249 +A+ R +WV++D++Y VF +T+IA P + +RT+ +N VSK Y MTGWR Sbjct: 188 AIADVLLRHPQVWVLTDDMYEHLVFDDFEFTTIAQVEPKLYDRTLTMNGVSKGYSMTGWR 247 Query: 250 IGYSAAPAAVTGAMLRLQSHTTSNPXXXXXXXXXXXXDGPQDDLEDIRGEYATRRSVLVE 309 IGY+A P + AM ++ S TTSNP +G QD ++ + RR ++V Sbjct: 248 IGYAAGPEPLIKAMGKMISQTTSNPCSISQWAALEALNGTQDFIKPNAKLFQERRDLVVS 307 Query: 310 GVRRIKGLECSVPDGAFYVWVDASAWRGQTL-EGQTISTADDLADILLKKAGVAVMPGTG 368 + + GL C P+GAFYV+ + G+T G+ I + +D A LL+ GVAV+ G Sbjct: 308 MLNQATGLHCPTPEGAFYVYPSCAGLIGKTAPSGKVIESDEDFATELLESEGVAVVHGAA 367 Query: 369 FGSPYHIRLSYAVSRDEMESGIAAMESILGS 399 FG R+SYA S + +E + ++ S Sbjct: 368 FGLSPFFRISYATSNEVLEDACSRIQRFCAS 398 >CAC1819 [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase Length = 398 Score = 295 bits (754), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 144/387 (37%), Positives = 222/387 (57%), Gaps = 2/387 (0%) Query: 14 RVQPSPTALLESTVARYQREGRTVYRLGLGQPDFPTPDRAKAAAIQAIQDNFTGYTDTGG 73 ++ S T + + + G V G GQPDF TP + AAI AI++ +T YT G Sbjct: 9 QIAASITLEITAKADEMKANGINVIGFGAGQPDFNTPKNIRDAAIYAIENGYTKYTPVSG 68 Query: 74 ILPLREAICRALLRDMGLSYDPGDIVVTVGGKHALFNAICTLCRPGDEVLIPIPYWVSFP 133 I L+ AIC RD L+Y +I+V+ G K L + L PGDEV++ PYWV++P Sbjct: 69 IKELKMAICDKFKRDNNLNYSLSNIIVSTGAKQCLSDTFSALLNPGDEVILSAPYWVTYP 128 Query: 134 EQVKFAGAKPVFVQTVASSGYKVTPETLTPWVNESTRLLILNQPNNPSGAVYSAAELAKL 193 E +K V + T + +K++ + L T+ +++N P+NP+G VY+ EL + Sbjct: 129 ELIKLNDGISVIINTTEENHFKLSVDDLENAYTSKTKAILINSPSNPTGTVYTETELKAI 188 Query: 194 AEFCRQRDLWVISDEVYSAFVFKPEGYTSIASFP-GMRERTVVINAVSKSYGMTGWRIGY 252 AEF +++DL++ISDE+Y ++ E + SIAS RTVVIN +SKSY MTGWR+GY Sbjct: 189 AEFAKEKDLFIISDEIYEKLIYDGERHVSIASLSQDAFNRTVVINGMSKSYAMTGWRLGY 248 Query: 253 SAAPAA-VTGAMLRLQSHTTSNPXXXXXXXXXXXXDGPQDDLEDIRGEYATRRSVLVEGV 311 +A+ ++ M +Q+HTTSN +G Q++L + E+ RR+ + + V Sbjct: 249 AASGSSEFIKLMSHIQAHTTSNANSITQYASVEALNGRQEELHSMVTEFEKRRTYMSKRV 308 Query: 312 RRIKGLECSVPDGAFYVWVDASAWRGQTLEGQTISTADDLADILLKKAGVAVMPGTGFGS 371 I G+ C +P GAFYV ++ S G+ + G I+ + D + LL + VAV+PGTGFG+ Sbjct: 309 NNITGIHCLLPKGAFYVMMNISNLFGKEINGVKINNSVDFSKELLSENKVAVVPGTGFGN 368 Query: 372 PYHIRLSYAVSRDEMESGIAAMESILG 398 ++RLSYA S D + G+ +E+ +G Sbjct: 369 DNYVRLSYATSMDNIVKGLDEIENFIG 395 >aq_1969 [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase Length = 340 Score = 290 bits (742), Expect = 3e-78, Method: Compositional matrix adjust. Identities = 0/393 (0%), Positives = 0/393 (0%), Gaps = 9/393 (2%) Query: 8 LADWVERVQPSPTALLESTVARYQREGRTVYRLGLGQPDFPTPDRAKAAAIQAIQDNFTG 67 + + E + +G T + + Sbjct: 5 RELLRKIAEFENLTAEEMYNLMKEVAEGRATDAQIGALVMGTKMKGETPEEIEGAVKLFR 64 Query: 68 YTDTGGILPLREAICRALLRDMGLSYDPGDIVVTVGGKHALFNAICTLCRPGDEVLIPIP 127 + E + + S VT + Sbjct: 65 EKVVRVPVKDPEELVDVVGTGGDKSSTFNVSTVTGFVLAGAGVKVAKHGNRSVSSKSGSA 124 Query: 128 YWVSFPEQVKFAGAKPVFVQTVASSGYKVTPETLTPWVNESTRLLILNQPNNPSGAVYSA 187 ++ + V + P + + + Sbjct: 125 DFLEALGAKVELLPEKVARLIEEVGFGFMFAPLFHPAMKRVVSPRREVGVRSIFNLIGPL 184 Query: 188 AELAKLAEFCRQRDLWVISDEVYSAFVFKPEGYTSIASFPG-MRERTVVINAVSKSYGMT 246 A + + D+ A + G + E +V Sbjct: 185 TNPAGVKRYLLGVFSKEYVDKFAKALKNLGVKKAFVVHGEGGIDEVSVEGETYVTEVSEE 244 Query: 247 GWRIGYSAAPAAVTGAMLRLQSHTTSNPXXXXXXXXXXXXDGP--QDDLEDIRGEYATRR 304 G R + + S + +D + Sbjct: 245 GIRSFTFSPEELGVKRKSLSEVRVNSPEESVKVALSVLRGEEGTPRDMVLLNASFGILVS 304 Query: 305 SVLVEGVRRIKGLECSVPDGAFYVWVDASAWRGQTLEGQTISTADDLADILLKKAGVAVM 364 + + + S+ G ++ Sbjct: 305 ERAGDIKEAFEMAKESIDSGKALEVLEKYVE------ 358 Query: 365 PGTGFGSPYHIRLSYAVSRDEMESGIAAMESIL 397 Sbjct: 359 391 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.135 0.406 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 30,497,992 Number of extensions: 1252585 Number of successful extensions: 3426 Number of sequences better than 1.0e-05: 245 Number of HSP's gapped: 2926 Number of HSP's successfully gapped: 247 Length of query: 400 Length of database: 38,378,431 Length adjustment: 109 Effective length of query: 291 Effective length of database: 25,807,025 Effective search space: 7509844275 Effective search space used: 7509844275 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 117 (49.7 bits)