BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0128.0033.p (385 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGpA709 [E] COG0624 Acetylornithine deacetylase/Succinyl-diamino... 244 2e-64 mlr1185 [E] COG0624 Acetylornithine deacetylase/Succinyl-diamino... 152 6e-37 lin0289 [E] COG0624 Acetylornithine deacetylase/Succinyl-diamino... 142 8e-34 AGl2847 [E] COG0624 Acetylornithine deacetylase/Succinyl-diamino... 135 8e-32 PAE2335 [E] COG0624 Acetylornithine deacetylase/Succinyl-diamino... 135 1e-31 >AGpA709 [E] COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Length = 204 Score = 244 bits (623), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 0/375 (0%), Positives = 0/375 (0%), Gaps = 3/375 (0%) Query: 10 RVIQLLADLIGFQSVNPGGTEGDAAAYVAKVMRKAGCEVELQEIEPGRPNVIARLKGAGG 69 ++ + ++ + + ++ + L G Sbjct: 9 AIVDQYSHCEWVENSMSANENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAE-GP 67 Query: 70 GRTIILNTHMDVVPAGEGWSSDPFTLLRKGERVYGRGVMDAKGPLXXXXXXXXXXXXXXX 129 + + + + + L + + G +A+ Sbjct: 68 TIAVHQSDEQLALMDDWNVRTHTASGLVERVKASTMGDREAELATLEFLKQWVPAGKSPI 127 Query: 130 HLPGDIVLAAVVDEEAASLGARNLPDNLHG-DLAVIGEATAGNLAVAHRGSIRPVLAAEG 188 + + L A L L + + + Sbjct: 128 CGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQGTHQAMDDI 187 Query: 189 VSAHSSTPHLGVNAVSLMVRTLMALEDFAEQELTKRLHPLTGQSTLSVTVINGGIKESMI 248 Sbjct: 188 247 Query: 249 PDRCEALIDRRLIPGEAEEDALQEIRQIIA-GLPALGGRVRIDRLVPTTGVASETRPDHP 307 Sbjct: 248 307 Query: 308 MVELAAAAIERVYGRRPELTGLTANCDMTHFVKRGIPSVIYGPGDFSVAHTIGEWVTVSE 367 Sbjct: 308 367 Query: 368 LENASRVYASIAMEV 382 Sbjct: 368 382 >mlr1185 [E] COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Length = 204 Score = 152 bits (385), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 0/411 (0%), Positives = 0/411 (0%), Gaps = 50/411 (12%) Query: 7 RSERVIQLLADLIGFQSVNP-GGTEGDAAAYVAKVMRKAGCEVELQEIE--PG------R 57 + + + + N + + Sbjct: 12 DQYSHCEWVENSMSANENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPTIAV 71 Query: 58 PNVIARLKGAGGGRTIILNTHMDVVPAGEGWSSDPFTLLRKGERVYGRGVMDAKGPLXXX 117 +L V D L E + Sbjct: 72 HQSDEQLALMDDWNVRTHTASGLVERVKASTMGDREAELATLEFLKQWVPAGKSPICGNS 131 Query: 118 XXXXXXXXXXXXHLPGDIVLAAVVDEEA---------ASLGARNLPDNLHGDLAVIGEA- 167 +D + H + + Sbjct: 132 IGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQGTH---QAMDDIR 188 Query: 168 TAGNLAVAHRGSIRPVLAAEGVSAHSSTPHLGVNAVSLMVRTLMALEDFAEQELTKRLHP 227 Sbjct: 189 248 Query: 228 L------TGQSTLSVTVINGGIKESM--------IPDRCEALIDRRLIPGEAEEDALQEI 273 Sbjct: 249 ---- 304 Query: 274 RQIIAGLPALGGRVR------IDRLVPTTGVASETRPDHPMVELAAAAIERVYGRRPELT 327 Sbjct: 305 -- 362 Query: 328 GLTANCDMTHFVKRG--IPSVIYGPGDFSVAHTIGEWVTVSELENASRVYA 376 Sbjct: 363 413 >lin0289 [E] COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Length = 204 Score = 142 bits (358), Expect = 8e-34, Method: Compositional matrix adjust. Identities = 0/383 (0%), Positives = 0/383 (0%), Gaps = 18/383 (4%) Query: 9 ERVIQLLADLIGFQSVNPGGTEGDAAAYVAKVMRKAGCEVELQEIEPGRPNVIARLKGAG 68 +I + D A + ++ + + Sbjct: 4 TSMIHAIVDQYSHCEWV--ENSMSANENNLIWIDLEMTGLDPERDRIIEIATLVTD-ANL 60 Query: 69 GGRTIILNTHMDVVPAGE--GWSSDPFTLLRKGERVYGRGVMDAKGPLXXXXXXXXXXXX 126 + + T G + Sbjct: 61 NILAEGPTIAVHQSDEQLALMDDWNVRTHTASGLVERVKASTMGDREAELATLEFLKQWV 120 Query: 127 XXXHLPGDIVLAAVVDEEAASLGARNLP-----DNLHGDLAVIGEATAGNLAVAHRGSIR 181 P + A + + + Sbjct: 121 PAGKSPICGNSIGQDRRFLFKYMPELEAYFHYRYLDVS--TLKELARRWKPEILDGFTKQ 178 Query: 182 PVLAAEGVSAHSSTPHLGVNAVSLMVRTLMALEDFAEQELTKRLHPLTGQSTLSVTVING 241 Sbjct: 179 -- 236 Query: 242 GIKESMIPDRCEALIDRRLIPGEAEEDALQEIRQIIAGLPALGGRVRIDRLVPTTGVASE 301 Sbjct: 237 - 295 Query: 302 TRPDHPMVELAAAAIERVYGRRPELTGLTANCDMTHFV--KRGIPSVIYGPGDFSVAHTI 359 Sbjct: 296 - 354 Query: 360 GEWVTVSELENASRVYASIAMEV 382 Sbjct: 355 377 >AGl2847 [E] COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Length = 204 Score = 135 bits (341), Expect = 8e-32, Method: Compositional matrix adjust. Identities = 0/385 (0%), Positives = 0/385 (0%), Gaps = 36/385 (9%) Query: 12 IQLLADLIGFQSVNPGGTEGDAAAYVAKVMRKAGCEVE-LQEIEPGRPNVIARLKGAGGG 70 ++ ++ S E +A ++ E + A Sbjct: 4 TSMIHAIVDQYSHC-EWVENSMSANENNLIWIDLEMTGLDPERDRIIEIATLVT-DANLN 61 Query: 71 RTIILNTHMDVVPAGEG-WSSDPFTLLRKGERVYGRGVMDAKGPLXXXXXXXXXXXXXXX 129 T + D + R G Sbjct: 62 ILAEGPTIAVHQSDEQLALMDDWNVRTHTASGLVERVKASTMGDREAELATLEFLKQWVP 121 Query: 130 HLPGDIVLAAVVDEEAASLGARNLPDNLHGDL-----AVIGEATAGNLAVAHRGSIRPVL 184 I + + +P+ + A Sbjct: 122 AGKSPICGN--SIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQG 179 Query: 185 AAEGVSAHSSTPHLGVNAVSLMVRTLMALEDFAEQELTKRLHPLTGQ---STLSVTVING 241 + + + + Sbjct: 180 THQAMDDIRESVAELAYYREHFI- 238 Query: 242 GIKESMIPDRCEALIDRRLIPGEAEEDALQEIRQIIAGLPALGGRVRIDRLVPTTGVASE 301 Sbjct: 239 ------------- 285 Query: 302 TRP--DHPMVELAAAA-----IERVYGRRPELTGLTANCDMTHFVKRGIPSVIYGPGDFS 354 Sbjct: 286 - 344 Query: 355 VAHTIGEWVTVSELENASRVYASIA 379 Sbjct: 345 369 >PAE2335 [E] COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Length = 204 Score = 135 bits (340), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 0/418 (0%), Positives = 0/418 (0%), Gaps = 71/418 (16%) Query: 10 RVIQLLADLIGFQSVNPGGTE-GDAAAYVAKVMRKAGCEVELQEIEPGR----------- 57 + + + + + G + E I Sbjct: 4 TSMIHAIVDQYSHCEWVENSMSANENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNIL 63 Query: 58 PNVIARLKGAGGGRTIILNTHMDVVPAG--EGWS-SDPFTLLRKGERVYGRGVMDAKGPL 114 + V G + + E + Sbjct: 64 AEGP--TIAVHQSDEQLALMDDWNVRTHTASGLVERVKASTMGDREAELATLEFLKQWVP 121 Query: 115 XXXXXXXXXXXXXXXHLPGDIVLAAVVDEEAASLGARNLPDNLHGDLAVIGEATAG---- 170 + R L + A Sbjct: 122 A------------------GKSPIC---GNSIGQDRRFLFKYMPELEAYFHYRYLDVSTL 160 Query: 171 ------------------NLAVAHRGSIRPVLAAEGVSAHSSTPHLGVNAVSLMVRTLMA 212 Sbjct: 161 KELARRWKPEILDGFTKQ 220 Query: 213 LEDFAEQELTKRLH-----PLTGQSTLSVT-VINGGIKESMIPDRCEALIDRRLIPGEAE 266 Sbjct: 221 --- 277 Query: 267 EDALQEIRQIIAGLPALGGRV--RIDRLVPTTGVASETRPDHPMVELAAAAIERVYGRRP 324 Sbjct: 278 337 Query: 325 ELTGLTANCDMTHFVKRGIPSVIYGPGDFSVAHTIGEWVTVSELENASRVYASIAMEV 382 Sbjct: 338 395 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.317 0.135 0.389 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 28,147,201 Number of extensions: 1209446 Number of successful extensions: 3382 Number of sequences better than 1.0e-05: 94 Number of HSP's gapped: 3219 Number of HSP's successfully gapped: 95 Length of query: 385 Length of database: 38,378,431 Length adjustment: 108 Effective length of query: 277 Effective length of database: 25,922,359 Effective search space: 7180493443 Effective search space used: 7180493443 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 117 (49.7 bits)