BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0128.0004.p (536 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH2109 [T] COG4753 Response regulator containing CheY-like recei... 162 1e-39 BH1123 [T] COG4753 Response regulator containing CheY-like recei... 162 2e-39 BH2728 [T] COG4753 Response regulator containing CheY-like recei... 144 3e-34 SPy1587 [T] COG4753 Response regulator containing CheY-like rece... 129 2e-29 BH0483 [K] COG2207 AraC-type DNA-binding domain-containing proteins 115 2e-25 >BH2109 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 525 Score = 162 bits (410), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 130/544 (23%), Positives = 257/544 (47%), Gaps = 36/544 (6%) Query: 1 MIVADDEPFIRRSLIQVFNWQEEFGIEIIGEASDGQEAYELCMELQPDILFTDIMMPMLG 60 +++ADDE F+R L + W E+ G E+ EA +G++A++L E++PD++ TDI MP+ Sbjct: 4 VLLADDEFFVRHGLKSLIEW-EKCGYEVAAEADNGEDAFKLVQEIKPDLVITDIRMPVFD 62 Query: 61 GLEVAEKLKAG-QCRTRIIIISGAQDFSYAQSALKVNAEGYILKPVKLPELREVFQEVVS 119 GL++ +K+ T+ IIISG DFSYAQ A++ A ++LKP+ EL ++ + Sbjct: 63 GLQLIQKVNETLSFNTKFIIISGYNDFSYAQKAVRFGAVDFVLKPIDQDELEAALIKLAA 122 Query: 120 RLRGEKDQQMNVEQ-LRRQVQTHM--PLIREKFLQNWAAGLYRDEGELWEKIGYFQLPFR 176 L EK + E+ L Q+ H +E ++ WAA L + + Y+ L Sbjct: 123 TLDQEKATNSDQEKVLLDQIFIHSLGENKKENEVRRWAAKLNINNRHFY----YYLLLEV 178 Query: 177 PGDVLTAGVLQLDDYQSAVDKFSEDDKQLLYFSIQNIISECLEHPPGGVSFAASENEFMI 236 L G + +++ E I+ +I E + + A + Sbjct: 179 NNLSLDKGFIN--------EQYKE--------PIRKVIRETVARQAATEEYTAIYEQLDH 222 Query: 237 IFG---PDEGASPGEGAIAGFCEKIIGSIHKYLRLDASIGVGRACTRVSELEDSYKDALA 293 +G E G I EK+ I + + ++ VG +S ++ SY+ A + Sbjct: 223 AYGLLITSEHLKKFNGQIEPLAEKLRKDIQDFTNIPLTVYVGAKTDDLSTIKKSYETANS 282 Query: 294 ALVHTFYTGSRSILHIRDIQPGTETLQSAFFYKFHARLMNELKAGHTEQVMELLEKLFDR 353 + + +++ I + +T LM +++ ++++++ +++K+F Sbjct: 283 LRNYKYIFNEKNVF-IHEQTESVDTTYDELNNHLFVTLMEQMEENNSDRIVNIIDKIFSE 341 Query: 354 LTAPKLQIDYVQSICAEMIFTSARALYELDEDIERVLQDRLTIMDTLYRHKNLS--GLKA 411 K V++ + + + ++ D +++ + T + NL+ LK Sbjct: 342 FQTKKFVPSAVKTSVNRCVHKVMQTVQAMEGDTGKIISAQAM---TNWESYNLTFDQLKQ 398 Query: 412 YVLSLFYDLSAYMAGKNSSRNSKT-INRIRAIVQEGYAQELSIARIAEEVFLTPNYISLI 470 V + F +A + + N K+ I +++ ++ Y + +S+ IA ++ P Y+ + Sbjct: 399 -VFTKFVLEAAVIIQELRKENMKSDIYKVKTYIENHYHENISLKSIASLFYMNPVYMGQL 457 Query: 471 FKKETGETLTDYITRIRIDKAKELLSTTDLKVMEISGLVGYENPHYFSTVFKKSVGVHPL 530 FKK G +Y+ ++R+++AK+LL TD++V E++ VG+ + YF T F+K + P Sbjct: 458 FKKTFGVYFKEYLLKLRMNEAKKLLRQTDMRVYEVAERVGFGSTDYFVTQFEKINKMTPT 517 Query: 531 KYRS 534 +YR+ Sbjct: 518 EYRN 521 >BH1123 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 526 Score = 162 bits (409), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 119/544 (21%), Positives = 256/544 (47%), Gaps = 43/544 (7%) Query: 1 MIVADDEPFIRRSLIQVFNWQEEFGIEIIGEASDGQEAYELCMELQPDILFTDIMMPMLG 60 +++ DDE + R L ++ +W+ G E +GEA++G+ ++ E P I+ TDI MP++ Sbjct: 4 VVIIDDEEHVVRGLKKIISWKA-LGCECVGEAANGRRGLDIVRETSPHIVLTDIYMPIMY 62 Query: 61 GLEVAEKLKAGQCRTRIIIISGAQDFSYAQSALKVNAEGYILKPVKLPELREVFQEVVSR 120 GL++ + L+ ++I+SG +F +A+ A+++N Y+ KP + + V + V+++ Sbjct: 63 GLDMIQILREDGFDGEVVILSGYSEFEHARKAMQLNITDYLSKPASVDTIETVLKRVINK 122 Query: 121 LRGEKDQQMNVEQLRRQVQTHMPLIREKFLQNWAAGLYRDEGELWEKIGYFQLPFRPGDV 180 L ++ QQ +++L +V+ + PL+ +++++ G R+ GE+ P + Sbjct: 123 LEEKQRQQGYLQELTNKVKRYEPLVETEWMKSLLTGRLRN-GEI------------PEEF 169 Query: 181 LTAGVLQLDDYQSAVDKFSEDDKQ----------LLYFSIQNIISECLEHPPGGVSFAAS 230 L A + + D Q + D Q L +S+ +I E L P + F Sbjct: 170 L-AKITKWKDQQHIACSLTYDGPQNKELKPADWYLFRYSVHKMIREVLNGYP--IDFRYL 226 Query: 231 E-NEFMIIFGPDEGASPGEGAIAGFC----EKIIGSIHKYLRLDASIGVGRACTRVSELE 285 E + + S E ++ +++ I+ + ++ GR ++L Sbjct: 227 EMDAYRSALCLHVNKSVSEPVLSCMLMEIKDQVEQGIYSSFNVKTTVHYGRVKEDWTDLS 286 Query: 286 DSYKDALAALVHTFYTGSRSILHIRDIQPGTETLQSAFFYKFHARLMNELKAGHTEQVME 345 +S+ +A +F G+ P + ++ F + +L + ++ + E Sbjct: 287 ESFHEACME-SQSFPLGN----------PYEDGTRATFPMESSQKLYDAIRYADATRAKE 335 Query: 346 LLEKLFDRLTAPKLQIDYVQSICAEMIFTSARALYELDEDIERVLQDRLTIMDTLYRHKN 405 +LE+ L + E+ +LY++ I+ + + + L + N Sbjct: 336 VLEEAVGVLGEVPYSTLVGYKVGIEIWTIITYSLYDIGILIQEMFDEDFDLAQHLTKQGN 395 Query: 406 LSGLKAYVLSLFYDLSAYMAGKNSSRNSKTINRIRAIVQEGYAQELSIARIAEEVFLTPN 465 ++ + + + ++ + I ++ +++ A+ +++ IA+E++++ N Sbjct: 396 WQEWIRFLCEQIEHICYHQQWDENIKHKQLIEQVMIYIEKHLAENITLQDIADELYISRN 455 Query: 466 YISLIFKKETGETLTDYITRIRIDKAKELLSTTDLKVMEISGLVGYENPHYFSTVFKKSV 525 Y+ IFKK GE+ +Y+TR+R++KAK+++ + + E+S VGY NP YF+T+FKK Sbjct: 456 YLGQIFKKVVGESFKNYVTRLRMEKAKKMIQEGNFLIYEVSEKVGYVNPAYFTTMFKKYT 515 Query: 526 GVHP 529 G P Sbjct: 516 GYTP 519 >BH2728 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 510 Score = 144 bits (363), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 128/537 (23%), Positives = 251/537 (46%), Gaps = 45/537 (8%) Query: 1 MIVADDEPFIRRSLIQVFNWQEEFGIEIIGEASDGQEAYELCMELQPDILFTDIMMPMLG 60 +++ DDE IR+ +I F+W++E G +I+GEA++G++A EL + +P I+ TDI+MP++ Sbjct: 4 VLIVDDEKLIRQGIINFFDWEKE-GFQIVGEAANGKDALELISKNEPHIVMTDIVMPVMD 62 Query: 61 GLEVAEKLKAGQCRTRIIIISGAQDFSYAQSALKVNAEGYILKPVKLPELREVFQEVVSR 120 G+++ +++K II++S ++F Y +S YILKP +L E + + +S Sbjct: 63 GIDLVKRVKRDFPEVEIIVLSSFEEFEYVRSTFHSGVADYILKP-RLNE--KDLLKTLSE 119 Query: 121 LRGEKDQQMNVEQLRRQVQTHMPLIREKF--LQNWAAGLYRDEGELWEKIGYFQLPFRPG 178 +RG+ V+ R V P I ++F + N A L +D+ G + P P Sbjct: 120 VRGKIPALAKVDSPSRAV----PSISDQFEKILNGHAPLSQDD------TGEKRFPKGPY 169 Query: 179 DVLTAGVLQLDDYQSAVDKFSEDDKQLLYFSIQNIISECLEHPPGGVSFAASENEFMIIF 238 + ++ D E ++ + + V E + +++ Sbjct: 170 RLAVITPIEEQDVHRRKQHLDEREQAITGIDV--------------VCSIEKEGDAVLLL 215 Query: 239 GPDEGASPGEGAIAGFCEKIIGSIHKYLRLDASIGVGRACTRVSELEDSYKDALAALV-H 297 P EG ++ ++ + K R ++ V + + E ++ Y+ + L + Sbjct: 216 -------PLEGDVSSSMKQALDDFLK-GRDAHALLVSSPFSSIYEAKEVYERDIPLLKQY 267 Query: 298 TFYTGSRSILHIRDIQPGTETLQSAFFYKFHARLMNELK-AGHTEQVMELLEKLFDRLTA 356 +FY +L I D P T F L K A + +++ +E + R T Sbjct: 268 SFYLPDTPLL-IYDELPKTNEGVKTFDLNHFIELCKGRKFAIGFQYLLDYVEYMSTRYTQ 326 Query: 357 PKLQIDYVQSICAEMIFTSARALYELDEDIERVLQDRLTIMDTLYRHKNLSGLKAYVLSL 416 + ++ +IF + L D++ + +++ T+ KN+ Sbjct: 327 TSTE---CKAFLGNIIFNMIVLMGNLKYDVKELEREKYHYFATINAAKNVREATD-CFYQ 382 Query: 417 FYDLSAYMAGKNSSRNSKTINRIRAIVQEGYAQELSIARIAEEVFLTPNYISLIFKKETG 476 F +++ + S+ S +I ++ A ++E +++ LS++++A P+Y+S F++ Sbjct: 383 FLEVTKQIISVYSNEGSSSIQKMLAYIEEHHSEPLSLSQLANYFHFNPSYLSAYFRQHHD 442 Query: 477 ETLTDYITRIRIDKAKELLSTTDLKVMEISGLVGYENPHYFSTVFKKSVGVHPLKYR 533 E ++Y+ ++RI KAKE L ++ + + EI LVGY + YF VFKK G+ P +YR Sbjct: 443 EGFSEYLNKVRIRKAKEWLKSSTIPISEIYALVGYSDHSYFCKVFKKRTGMPPSRYR 499 >SPy1587 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 494 Score = 129 bits (323), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 135/555 (24%), Positives = 236/555 (42%), Gaps = 100/555 (18%) Query: 1 MIVADDEPFIRRSLIQVFNWQEEFGIEIIGEASDGQEAYELCMELQPDILFTDIMMPMLG 60 +++ DDE I + L + +WQ G E++ A G+EA + D++ +D+ MP + Sbjct: 4 VLLVDDEYMILQGLTMIIDWQA-LGFEVVQTARSGKEALAYLTQYPVDVMISDVTMPGMT 62 Query: 61 GLEVAEKLKAGQCRTRIIIISGAQDFSYAQSALKVNAEGYILKPVKLPELREVFQEVVSR 120 GL++ E K + + +I+SG Q+FSY Q A+++ +GY+LKPV EL+ ++ Sbjct: 63 GLDLIEAAKTYHPQLQTLILSGYQEFSYVQKAMELETKGYLLKPVDKAELQAKMKQFKDW 122 Query: 121 LRGEKDQQMNVEQLRRQVQTHMPL--IREKFLQNWAAGLYRDEGELWEKIGYFQLPFRPG 178 L ++ + + E + T + EK Q + GL P Sbjct: 123 LDAQQAESIRQEAYHDSLLTLWLTDELSEKEFQQLSQGL-------------------PA 163 Query: 179 DVLTA-GVLQLD--DYQSAVDKFSEDDKQLLYFSIQNIISECLEHPPGGVSFAASENEFM 235 LT VL LD ++Q+A+D + E + Q Y + V A Sbjct: 164 AALTGFTVLYLDCQEWQAAIDAYFEREGQPFYLK---------KEEDKKVYLA------- 207 Query: 236 IIFGPDEGASPGEGAIAGFCEKIIGSIHKYLRLDASIGVGRACTRVSELEDSYKDALAAL 295 ++ G + A + ++ ++H+ + +G + +SY L +L Sbjct: 208 VLLGKTDQA---KAFTYDLQKRFSRNMHQLI-------LGETVDDWENVYESYNQVLKSL 257 Query: 296 VHTFYTGSRSILHIRD---IQPGTETLQSAFFYKFHARLMNELKAGHTEQVMELLEKLFD 352 FY S + +D I+ LQ F+ F+ LM G ++ LE +FD Sbjct: 258 ---FYNCEVSPIRAKDKSKIELPESRLQ---FFAFNKALM----IGDEPTILSKLEAIFD 307 Query: 353 RLTAPKLQIDYVQS--------------ICAEMIFTSARALYELDEDIERVLQDRLTIMD 398 + + V+ I +M + S + I+ +L++ ++D Sbjct: 308 EMKTLNFSPEDVKHVSFLLFSDIYRQFPILDKMTYLSMVKTIHDSQSIDCILRELKKVLD 367 Query: 399 TLYRHKNLSGLKAYVLSLFYDLSAYMAGKNSSRNSKTINRIRAIVQEGYAQELSIARIAE 458 ++N S K Y S S+TI+ IR + Y QEL++ IA+ Sbjct: 368 V--TNQNNSPEKRY----------------SDLVSETIDCIR----KEYHQELTLKAIAD 405 Query: 459 EVFLTPNYISLIFKKETGETLTDYITRIRIDKAKELLSTTDLKVMEISGLVGYENPHYFS 518 + + Y+ FK ET + T Y+ +RI KA++LL T+ + EI+ GY HYF Sbjct: 406 RLHVNGVYLGQCFKNETERSFTQYLNHVRIQKAQQLLLYTNQSINEIAYETGYNTNHYFI 465 Query: 519 TVFKKSVGVHPLKYR 533 +FKK G+ P ++R Sbjct: 466 KMFKKLNGLSPKEFR 480 >BH0483 [K] COG2207 AraC-type DNA-binding domain-containing proteins Length = 769 Score = 115 bits (288), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 98/407 (24%), Positives = 188/407 (46%), Gaps = 11/407 (2%) Query: 133 QLRRQVQTHMPLIREKFLQNWAAGLYRDEGELWEKIGYFQLP--FRPGDVLTAGVLQLDD 190 +L ++Q + +++ F+ N G + E+ K FQ P +R VLT LQ+D Sbjct: 369 ELEEKLQGQIKQLKQFFVLNLIKG-HMSPSEIETKYETFQYPKDWRQLHVLT---LQIDS 424 Query: 191 YQSAVDKFSEDDKQLLYFSIQNIISECLEHPPGGVSFAASENEFMIIFGPDEGASPGEGA 250 + K+++++K +L FSI N++ + + +I+ + +G Sbjct: 425 LEGT--KYAKEEKDVLLFSINNLVETLIPEVERLTPALLNNTVVLILLTNVDQEQKRDGF 482 Query: 251 IAGFCEKIIGSIHKYLRLDASIGVGRACTRVSELEDSYKDALAALVHTFYTGSRSILHIR 310 + E I+ + + L + SIGV +++ +++Y + + AL + G +S++ Sbjct: 483 VREKAEAIMNEVRQQLDISVSIGVSLPYDDITKTQEAYDEGIEALKYRIKLGCQSVIFFS 542 Query: 311 DIQPGTETLQSAFFYKFHARLMNELKAGHTEQVMELLEKLFDRLTAPKLQIDYVQSICAE 370 ++ T + + + + L + LK G V + L+ L D + L Q Sbjct: 543 NL-AHTHSFHTYYPKQQENELFDALKLGDKSNVKDHLDALIDGIFQKDLHPSQYQISLLR 601 Query: 371 MIFTSARALYELDEDIERVLQDRLTIMDTLYRHKNLSGLKAYVLSLFYDLSAYMAGKNSS 430 ++ + + L L D V D+ T+ D L+ + + +K + + S + + Sbjct: 602 LLNNTIQLLQTLGIDSVDVY-DKKTLFDQLFSLQTIDEVKQWFFTKLIAPSVHTVAERMD 660 Query: 431 RNSKTI-NRIRAIVQEGYAQELSIARIAEEVFLTPNYISLIFKKETGETLTDYITRIRID 489 +TI ++I I+Q + EL++ IAE + PNY+S IF+KET + ++Y++ R+ Sbjct: 661 SQYRTISDQIIHIIQNEFDMELTLESIAERLHYNPNYLSSIFRKETNISFSEYLSSYRLA 720 Query: 490 KAKELLSTTDLKVMEISGLVGYENPHYFSTVFKKSVGVHPLKYRSGK 536 AK+ L T + + EI+ + Y N F FKK G+ P KYR K Sbjct: 721 MAKKWLLETSMPIREIAERLCYGNSQNFIRSFKKKEGMTPGKYRQSK 767 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.137 0.392 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 38,083,161 Number of extensions: 1572397 Number of successful extensions: 7457 Number of sequences better than 1.0e-05: 254 Number of HSP's gapped: 7550 Number of HSP's successfully gapped: 265 Length of query: 536 Length of database: 38,378,431 Length adjustment: 111 Effective length of query: 425 Effective length of database: 25,576,357 Effective search space: 10869951725 Effective search space used: 10869951725 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 118 (50.1 bits)