BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0126.0020.p (607 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH1909 [T] COG2972 Predicted signal transduction protein with a ... 161 3e-39 BS_yesM [T] COG2972 Predicted signal transduction protein with a... 146 1e-34 BH2110 [T] COG2972 Predicted signal transduction protein with a ... 130 9e-30 BH0792 [T] COG2972 Predicted signal transduction protein with a ... 129 2e-29 lin2119 [T] COG2972 Predicted signal transduction protein with a... 118 3e-26 >BH1909 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain Length = 597 Score = 161 bits (407), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 144/526 (27%), Positives = 236/526 (44%), Gaps = 60/526 (11%) Query: 91 LQYIMYNN-----PNISNLRFFTSNKYAREIWPIIYNERRIAGENWANEFYAQPEAVWWT 145 LQY+ + N I N+++++ N W II E AGE W E A P W Sbjct: 103 LQYMNFTNYLQYYSEIHNMKYYSENTSLMNNWVIIPVEHE-AGEEWFKEAMADPAYYRW- 160 Query: 146 IYRGPEELRGSTEGERQDYLNFASLVREVKYPLDQHLALLQVNMRLDVFFSNIYGNLQEA 205 Y E + Q YL+ + ++Y L + +LD LQ+ Sbjct: 161 FYLEDETKKN------QAYLSMVKRLNFLEYGSAGVLVITVDPRKLDRI-------LQQE 207 Query: 206 STQLLAIDRNSHLYYNGTSSFYEKIAPEDIRSEFALHTQGSEGN--FQFTHEGIPYLCL- 262 S + +D + + + K D+ H EG ++ G P + Sbjct: 208 SFTTMIVDERNRIAATNQREYIGK----DLHEVIDFHEMIQEGPAIYEGKMNGEPSQIIV 263 Query: 263 -YTSIERXXXXXXXXXXXXXXYNDMNKTRLAIGGATL----MLVLILSLITYKLLSVILK 317 Y +++ + + RL+I GAT+ M V +L ++ + L I K Sbjct: 264 DYLTLQMSQSELKIISIVTKEHIMKDAKRLSIMGATVTMGGMAVAVLLIVHFSWL--ISK 321 Query: 318 RLHLLRDSMKKVRQGDFNVEIPQLGGDEVGELGNHIRQMLSKINELIAEA--VNKQA--- 372 RL L + + +V GD +I G DE+G+L QM++ + LI + N+Q Sbjct: 322 RLSHLSERINQVASGDLKTKIVVDGKDEIGQLSVQFNQMVANLRSLIHQVHETNRQKRLL 381 Query: 373 --SSKEAELNSLKNQIDAHFLYNTLENLKMLAEIEGQLVISDTLTSLGAMLRYNLHWTTH 430 S E +L L +QI+ HFL+NTLE+++M + ++G+ I+ + LG ++R +L T H Sbjct: 382 EKSQNEIKLKMLASQINPHFLFNTLESIRMKSHMKGETEIAKVVKQLGKLMRKSLEVTGH 441 Query: 431 YVRLYEEIQHIQNYIAVMNIRYGGKLELRLDVRQQYRQQEILKMSLQPIVENALKYGMNA 490 ++ L E+ ++ Y+ + RYG +L L + Q EIL + +QP+VENA+ +G+ Sbjct: 442 HIPLRNELDMVRCYLEIQTFRYGDRLHYELYIDPQSEMVEILPLIIQPLVENAVIHGLER 501 Query: 491 PGLRKRGLMIVIHAYEQDDFMYIEIRDNGAGISAERLYNINLALQLDPAAAAMYAPPVNG 550 + G + I + + + + D+G G+ E+L A M P Sbjct: 502 T---EDGGTVTISTIVNGNDLTVIVNDDGCGMDEEKL----------EAIQNMLHHPQEV 548 Query: 551 DSAYDTSGSGIGLRNVHLRIQLHYGKTSGLWLESVEGEYTKVTIKV 596 D G+ IGL NVH R+QL YGKTSGL +ES +G+ T V + Sbjct: 549 D------GNKIGLLNVHKRLQLTYGKTSGLIIESAKGKGTCVRFTI 588 >BS_yesM [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain Length = 577 Score = 146 bits (368), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 95/312 (30%), Positives = 154/312 (49%), Gaps = 33/312 (10%) Query: 290 RLAIGGATLMLVLILSLITYKLLSVILKRLHLLRDSMKKVR----QGDFNVEIPQLGGDE 345 + IG L+ ++ L K+ + I + + L +MK V+ + ++ +P+ DE Sbjct: 289 KTVIGTCFLLFFCVVLLFGRKIANSITEPIEQLVTAMKSVQHSGIEAGVSLSLPEHTQDE 348 Query: 346 VGELGNHIRQMLSKINELIAEAVNKQASSKEAELNSLKNQIDAHFLYNTLENLKMLAEIE 405 G L H M+ +INEL+ E V KQ KE EL +L+ QI+ HFLYNTLE++ LA+ Sbjct: 349 AGMLNRHFTVMMKRINELMEENVEKQLIIKETELKALQAQINPHFLYNTLESINWLAKAN 408 Query: 406 GQLVISDTLTSLGAMLRYNLHWTTHYVRLYEEIQHIQNYIAVMNIRYGGKLELRLDVRQQ 465 Q IS + SLG +LR ++H V + EE +++Y+ + R+ +L+ LD+ + Sbjct: 409 QQKQISKMVESLGFLLRNSIHMKKDIVTIQEEADIVRHYMTIQRFRFEERLKFTLDIDDE 468 Query: 466 YRQQEILKMSLQPIVENALKYGMNAPGLRKRGLMIVIHAYEQDDFMYIEIRDNGAGISAE 525 + I K++LQP+ ENA++Y + R I I A + + I + DNG Sbjct: 469 VKHCLIPKLTLQPLAENAIQYALEP---FTRPCAIRIQAKKAKGCVCITVEDNG------ 519 Query: 526 RLYNINLALQLDPAAAAMYAPPVNGDSAYDTSGSGIGLRNVHLRIQLHYGKTSGLWLESV 585 P ++G T G GIGL N+ RI L +G+ GL + S Sbjct: 520 --------------------PGMDGRILESTGGRGIGLWNIRERISLTFGEPYGLRIHSE 559 Query: 586 EGEYTKVTIKVP 597 + T++ I +P Sbjct: 560 HEKGTRIVITIP 571 >BH2110 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain Length = 585 Score = 130 bits (326), Expect = 9e-30, Method: Compositional matrix adjust. Identities = 89/308 (28%), Positives = 159/308 (51%), Gaps = 35/308 (11%) Query: 297 TLMLVLILSLITYKLLSVILKRLHLLRDSMKKVRQGDFNVEIPQLGGDEVGELGNHIRQM 356 TL++VLI I +LL V+ MK++++ F++ DE+GEL N +M Sbjct: 298 TLLIVLISKSIHSRLLRVL--------KHMKRMKKQKFDIINFPGDKDEIGELTNEFNKM 349 Query: 357 LSKINELIAEAV-------NKQASSKEAELNSLKNQIDAHFLYNTLENLKMLAEIEGQLV 409 IN LI E + Q K+A+L++L++QI+ HFL+N LE ++M + I+G+ Sbjct: 350 SQTINRLINEVYASNIEKKDLQLREKQAQLSALQSQINPHFLFNALETIRMRSMIKGEKE 409 Query: 410 ISDTLTSLGAMLRYNLHWTTHYVRLYEEIQHIQNYIAVMNIRYGGKLELRLDVRQQYRQQ 469 + + ++ + R +L W +V + +E+ I ++ + R+G K+E LD+ ++ Sbjct: 410 TAKIIQNMAKIFRNSLTWGKDWVTVRDELCLIICFLEIQKYRFGDKMEYELDIDEEAYDY 469 Query: 470 EILKMSLQPIVENALKYGMNAPGLRKRGLMIVIHAYEQDDFMYIEIRDNGAGISAERLYN 529 I M P VENA +G+ + ++++G+ I I + D + EI DNGAG+ E+L + Sbjct: 470 IIPNMVFLPFVENASIHGIES--VKEKGI-IQIRVEKNDGEIVYEISDNGAGMDEEKLAS 526 Query: 530 INLALQLDPAAAAMYAPPVNGDSAYDTSGSGIGLRNVHLRIQLHYGKTSGLWLESVEGEY 589 + L+ + + G +G++NV+ R++LHY + S G+ Sbjct: 527 LIETLKNE-----------------ENMGENVGIKNVYYRLKLHYKNHFDFSINSRPGQG 569 Query: 590 TKVTIKVP 597 T V IK+P Sbjct: 570 TTVQIKLP 577 >BH0792 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain Length = 587 Score = 129 bits (324), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 93/312 (29%), Positives = 166/312 (53%), Gaps = 34/312 (10%) Query: 298 LMLVLILSLITYKLLSVILK----RLHLLRDSMKKVRQGDFNVEIPQLGG--DEVGELGN 351 +L+L+L++++ L V L+ R++ L +MK+V+ G +V I + G D++ + N Sbjct: 289 FLLILLLTVVSIALPYVSLRGYLTRVNDLVQTMKEVQSGQLSVRI-ETGNVDDDLAMISN 347 Query: 352 HIRQMLSKINELIAEAVNKQASSKEAELNSLKNQIDAHFLYNTLENLKMLAEIEGQLVIS 411 + L ++ + I + + EAEL +L++QI+ HFLYNTLE ++M + EG + Sbjct: 348 TFNETLDELEDYIEKVYFSKLKQTEAELANLQSQINPHFLYNTLEAIRMKSLSEGGRTTA 407 Query: 412 DTLTSLGAMLRYNLHWTTHYVRLYEEIQHIQNYIAVMNIRYGGKLELRLDVRQQYRQQEI 471 + L + RY+L + V + +E+QH++ Y+ + NIR+ +L ++ V ++++ + Sbjct: 408 KMIVQLSYLFRYSLK-SADLVTIGDELQHVEQYVELFNIRFPNQLTFQVAVEEKHKHYVV 466 Query: 472 LKMSLQPIVENALKYGMNAPGLRKRG---LMIVIHAYEQDDFMYIEIRDNGAGISAERLY 528 LQP++EN L +G R+R + I+I EQ + I+I DNG GI +++ Sbjct: 467 PPFILQPLIENFLIHGFK----RERDDNQINIIIQEKEQT--LQIQIMDNGKGIPRKKVE 520 Query: 529 NINLALQLDPAAAAMYAPPVNGDSAYDTSGSGIGLRNVHLRIQLHYGKTSGLWLESVEGE 588 IN L S + S IGL NV+ R++L YG+ G+ ++S Sbjct: 521 EINERL-----------------SMTENSSHSIGLFNVNQRLRLRYGERFGVSVQSEPDV 563 Query: 589 YTKVTIKVPYLI 600 T VTI+ P +I Sbjct: 564 CTIVTIRTPMII 575 >lin2119 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain Length = 577 Score = 118 bits (295), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 79/308 (25%), Positives = 150/308 (48%), Gaps = 24/308 (7%) Query: 291 LAIGGATLMLVLILSLITYKLLSVILKRLHLLRDSMKKVRQGDFNVEIP-QLGGDEVGEL 349 L + G L+LV+ + + + KR+ + M +V G + ++P GDE+ + Sbjct: 286 LTLFGIGLLLVIFSISVNFVISRRYSKRILTIIGGMNRVENGTLDAKLPVDNNGDELTMI 345 Query: 350 GNHIRQMLSKINELIAEAVNKQASSKEAELNSLKNQIDAHFLYNTLENLKMLAEIEGQLV 409 M ++ + + + + ++A L +L+ Q+ HFLYN+LE ++M A +EG Sbjct: 346 SERFNHMTENLDAYVKKVYSLEMEEQKARLKALQGQMQPHFLYNSLEAIRMNARVEGAKE 405 Query: 410 ISDTLTSLGAMLRYNLHWTTHYVRLYEEIQHIQNYIAVMNIRYGGKLELRLDVRQQYRQQ 469 SD + L +LRY + L EEI +++ Y+ M +R+ ++L + + +++ Sbjct: 406 TSDMIYQLATLLRYTANH-REITTLGEEINYVKQYVRFMEMRHEQPIKLEIHIEKRFNHT 464 Query: 470 EILKMSLQPIVENALKYGMNAPGLRKRGLMIVIHAYEQDDFMYIEIRDNGAGISAERLYN 529 I + +LQP++EN KY + ++ I +++ + +I+DNG G+ AE+L Sbjct: 465 HIPRFALQPLIENFFKYAYK----ENQHPVVTITVTAENNNLQFQIKDNGKGMDAEKLKE 520 Query: 530 INLALQLDPAAAAMYAPPVNGDSAYDTSGSGIGLRNVHLRIQLHYGKTSGLWLESVEGEY 589 + + +S +T S IGL N++ R+QL YG+ L + S E Sbjct: 521 VQATI----------------ESKAET--SHIGLANLNKRLQLLYGEAYSLTITSKPNEG 562 Query: 590 TKVTIKVP 597 T + +VP Sbjct: 563 TIILFQVP 570 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.136 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 42,424,816 Number of extensions: 1749393 Number of successful extensions: 7593 Number of sequences better than 1.0e-05: 25 Number of HSP's gapped: 7555 Number of HSP's successfully gapped: 25 Length of query: 607 Length of database: 38,378,431 Length adjustment: 112 Effective length of query: 495 Effective length of database: 25,461,023 Effective search space: 12603206385 Effective search space used: 12603206385 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 119 (50.4 bits)