BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0126.0008.p
         (158 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

MA4669 [R] COG3324 Predicted enzyme related to lactoylglutathion...   116   1e-26
NMA2011 [QR] COG0500 SAM-dependent methyltransferases                  78   6e-15
MA2011 [R] COG3324 Predicted enzyme related to lactoylglutathion...    78   6e-15
Rv0911 [R] COG3324 Predicted enzyme related to lactoylglutathion...    57   1e-08
MT0934.1 [R] COG3324 Predicted enzyme related to lactoylglutathi...    57   1e-08

>MA4669 [R] COG3324 Predicted enzyme related to lactoylglutathione lyase
          Length = 129

 Score =  116 bits (291), Expect = 1e-26,   Method: Compositional matrix adjust.
 Identities = 60/131 (45%), Positives = 76/131 (58%), Gaps = 2/131 (1%)

Query: 28  MGRLVHFEIHVDDMERAKKFYGEVFGWTFEDWSEYAGMPYFGATTGDAGELGINGALMQR 87
           M R++HFEI  +D+ERAKKFY +VFGW  E W     M Y+  TTG   E GING +M+R
Sbjct: 1   MPRVIHFEIRAEDIERAKKFYEDVFGWKIEKWE--GPMEYWSITTGKQEEPGINGGMMRR 58

Query: 88  RGASPEPGQAMNGYACTMGVEDYDSTEAIILKLGGKLALPKYALPGMAWQGYYLDTEGNT 147
           +   P     ++ Y CT+ V D D     I K GGK+   K  + G+ W  Y LDTE N 
Sbjct: 59  QVGEPGADTPISTYICTIDVPDIDKYLNQIQKHGGKVTGEKRPITGVGWLAYCLDTEKNI 118

Query: 148 FGIHQPDKHAK 158
           FGI QPD  A+
Sbjct: 119 FGIMQPDMSAR 129


>NMA2011 [QR] COG0500 SAM-dependent methyltransferases
          Length = 123

 Score = 77.8 bits (190), Expect = 6e-15,   Method: Compositional matrix adjust.
 Identities = 49/131 (37%), Positives = 65/131 (49%), Gaps = 8/131 (6%)

Query: 28  MGRLVHFEIHVDDMERAKKFYGEVFGWTFEDWSEYAGMPYFGATTGDAGELGINGALMQR 87
           M  +VHF++  DD  RAKKFY E+FGW FE    +  M Y+   T D   L         
Sbjct: 1   MPTIVHFDVPADDPARAKKFYAELFGWKFE--KPFETMEYYLIETED---LEGKAGPGGG 55

Query: 88  RGASPEPGQAMNGYACTMGVEDYDSTEAIILKLGGKLALPKYALPGMAWQGYYLDTEGNT 147
            G    P Q +  Y     +E+Y S    + KLGGK+ + K A+PG  +     DTE NT
Sbjct: 56  LGKRGAPDQRIMNYIGVPSIEEYLSK---VEKLGGKVVMAKTAVPGWGYLAICTDTENNT 112

Query: 148 FGIHQPDKHAK 158
           FG+ Q +K  K
Sbjct: 113 FGLWQDEKETK 123


>MA2011 [R] COG3324 Predicted enzyme related to lactoylglutathione lyase
          Length = 123

 Score = 77.8 bits (190), Expect = 6e-15,   Method: Compositional matrix adjust.
 Identities = 49/131 (37%), Positives = 65/131 (49%), Gaps = 8/131 (6%)

Query: 28  MGRLVHFEIHVDDMERAKKFYGEVFGWTFEDWSEYAGMPYFGATTGDAGELGINGALMQR 87
           M  +VHF++  DD  RAKKFY E+FGW FE    +  M Y+   T D   L         
Sbjct: 1   MPTIVHFDVPADDPARAKKFYAELFGWKFE--KPFETMEYYLIETED---LEGKAGPGGG 55

Query: 88  RGASPEPGQAMNGYACTMGVEDYDSTEAIILKLGGKLALPKYALPGMAWQGYYLDTEGNT 147
            G    P Q +  Y     +E+Y S    + KLGGK+ + K A+PG  +     DTE NT
Sbjct: 56  LGKRGAPDQRIMNYIGVPSIEEYLSK---VEKLGGKVVMAKTAVPGWGYLAICTDTENNT 112

Query: 148 FGIHQPDKHAK 158
           FG+ Q +K  K
Sbjct: 113 FGLWQDEKETK 123


>Rv0911 [R] COG3324 Predicted enzyme related to lactoylglutathione lyase
          Length = 257

 Score = 57.4 bits (137), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 40/129 (31%), Positives = 58/129 (44%), Gaps = 9/129 (6%)

Query: 28  MGRLVHFEIHVDDMERAKKFYGEVFGWTFEDWSEYAGMPYFGATTGDAGELGINGALMQR 87
           +G     ++   D++RA+ FYG VFGW FE     AG  Y G      G   + G +  R
Sbjct: 9   LGAPCWIDLTTSDVDRAQDFYGTVFGWAFES----AGPDYGGYINAAKGGHPVAGLMANR 64

Query: 88  RGASPEPGQAMNGYACTMGVEDYDSTEAIILKLGGKLALPKYALPGMAWQGYYLDTEGNT 147
               PE  Q+ +G+A      D  +T A +   GG   L    +PG  +    +D  G  
Sbjct: 65  ----PE-FQSPDGWATYFHTVDIGATVAKLAAAGGSSCLDPMEVPGKGFMSLAVDPSGAA 119

Query: 148 FGIHQPDKH 156
           FG+ QP +H
Sbjct: 120 FGLWQPLQH 128


>MT0934.1 [R] COG3324 Predicted enzyme related to lactoylglutathione lyase
          Length = 144

 Score = 57.4 bits (137), Expect = 1e-08,   Method: Compositional matrix adjust.
 Identities = 7/129 (5%), Positives = 19/129 (14%), Gaps = 9/129 (6%)

Query: 28  MGRLVHFEIHVDDMERAKKFYGEVFGWTFEDWSEYAGMPYFGATTGDAGELGINGALMQR 87
              L   E  +   +  +          +               T     + + G   + 
Sbjct: 9   DVPLPPEEAWMHASDLTRYREWLTIHKVWRS----KLPEVLEKGTVVESYVEVKGMPNRI 64

Query: 88  RGASPEPGQAMNGYACTMGVEDYDSTEAIILKLGGKLALPKYALPGMAWQGYYLDTEGNT 147
                            M +         +  +         ++             G  
Sbjct: 65  ----KW-TIVRYKPPEGMTLNGDGVGGVKVKLIAKVAPKEHGSVVSFDVHLGGPALLGPI 119

Query: 148 FGIHQPDKH 156
             I      
Sbjct: 120 GMIVAAALR 128


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.318    0.139    0.430 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 14,125,381
Number of extensions: 657581
Number of successful extensions: 938
Number of sequences better than 1.0e-05: 11
Number of HSP's gapped: 932
Number of HSP's successfully gapped: 11
Length of query: 158
Length of database: 38,378,431
Length adjustment: 98
Effective length of query: 60
Effective length of database: 27,075,699
Effective search space: 1624541940
Effective search space used: 1624541940
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 111 (47.4 bits)