BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0124.0003.p (313 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC0241 [V] COG1131 ABC-type multidrug transport system, ATPase ... 306 3e-83 BS_yfiL [V] COG1131 ABC-type multidrug transport system, ATPase ... 288 9e-78 CAC0236 [V] COG1131 ABC-type multidrug transport system, ATPase ... 273 3e-73 CAC0169 [V] COG1131 ABC-type multidrug transport system, ATPase ... 263 2e-70 SPy0744 [V] COG1131 ABC-type multidrug transport system, ATPase ... 252 5e-67 >CAC0241 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 310 Score = 306 bits (783), Expect = 3e-83, Method: Compositional matrix adjust. Identities = 147/306 (48%), Positives = 209/306 (68%) Query: 8 LSDVVKRYDQKLTVDHVNFSIQEGEIFGLLGPNGAGKSTTISMICGLLKADGGDIVIDGL 67 + ++ K Y + VD +N I++GEI+GLLGPNGAGKSTTI+ I GL K D G+I I G Sbjct: 5 IKNLKKTYKEFTAVDSLNLKIEDGEIYGLLGPNGAGKSTTINTITGLTKVDSGEIKIFGK 64 Query: 68 SVLSKPLEVKKRIGLVPQELALYENMTATENVSFFXXXXXXXXXXXXERVEEALAFTGLS 127 +K+ IG+VPQ++A++ ++A ENV+FF ERV+EAL FTGL Sbjct: 65 RFNGSDTNIKRNIGVVPQDIAVFSELSAYENVAFFGKLNGLRGAVLKERVKEALDFTGLW 124 Query: 128 DRAKDKPSTFSGGMKRRLNIACAIMHRPKLIIMDEPTVGIDPQSRNHILESVKALNKLGS 187 DR K KP +SGGM+RRLNIACAI+HRPKLIIMDEPTVGIDPQSRNHIL+SVK LN++GS Sbjct: 125 DRRKSKPGQYSGGMQRRLNIACAIVHRPKLIIMDEPTVGIDPQSRNHILDSVKKLNEMGS 184 Query: 188 TVIYTSHYMEEVAAICDRVAIMDKGHIIACGTERELRERVAHEERIVVKAAHITPALIQE 247 T+IYTSHYMEE+ +C ++ I+D G IA GT+ +L+E +++EE++ ++ + +T L++ Sbjct: 185 TIIYTSHYMEEIETLCSKITIIDHGKEIATGTKEQLKEMISNEEKVELELSEVTDDLVEA 244 Query: 248 LGKHPRINRAELNGDTVELYLPSSQSELQDILFIFAKHEGVIASLNIEEPDLETLFLSLT 307 + + + N + + + + + I A+ + I S+N+E+P LE +FL+LT Sbjct: 245 VEGIKNVKKCRRNENMLVIVSDKNSENISTITAKIAEFKSKIISINVEKPSLEGVFLTLT 304 Query: 308 GRTLRD 313 GR LRD Sbjct: 305 GRKLRD 310 >BS_yfiL [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 134 Score = 288 bits (737), Expect = 9e-78, Method: Compositional matrix adjust. Identities = 0/306 (0%), Positives = 0/306 (0%), Gaps = 2/306 (0%) Query: 10 DVVKRYDQKLTVDHVNFSIQEGEIFGLLGPNGAGKSTTISMICGLLKADGGDIVIDGLSV 69 +K+ + + + A T+ ++ I Sbjct: 6 YALKKEKEMMKKFIAPLLALLVSGCQIDPYTHAPTLTSTDWYDVGMEDAISGSAIKDDDA 65 Query: 70 LSKPLEVKKRIGLVPQELALYENMTATENVSFFXXXXXXXXXXXXERVEEALAFTGLSDR 129 S + E T E + Sbjct: 66 FSDSQADRGLYLKGYAEGQKKTCQTDFTYARGLSGKSFPASCNNVENASQLHEVWQKGAD 125 Query: 130 AKDKPSTFSGGMKRRLNIACAIMHRPKLIIMDEPTVGIDPQSRNHILESVKALNKLGSTV 189 Sbjct: 126 185 Query: 190 IYTSHYMEEVAAICDRVAIMDKGHIIACGTERELRERVAHEERIVVKAAHITPALIQELG 249 Sbjct: 186 245 Query: 250 KHPRINRAELNGDTVELYLPSSQSE--LQDILFIFAKHEGVIASLNIEEPDLETLFLSLT 307 Sbjct: 246 305 Query: 308 GRTLRD 313 Sbjct: 306 311 >CAC0236 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 310 Score = 273 bits (697), Expect = 3e-73, Method: Compositional matrix adjust. Identities = 135/304 (44%), Positives = 193/304 (63%) Query: 8 LSDVVKRYDQKLTVDHVNFSIQEGEIFGLLGPNGAGKSTTISMICGLLKADGGDIVIDGL 67 + ++VKRY L VD+VN SI+EGEI GLLGPNGAGK+T I I GL K D G I I G+ Sbjct: 5 IKNLVKRYGDFLAVDNVNLSIEEGEILGLLGPNGAGKTTIIDCIIGLNKIDSGSIRIFGM 64 Query: 68 SVLSKPLEVKKRIGLVPQELALYENMTATENVSFFXXXXXXXXXXXXERVEEALAFTGLS 127 L + +KK IG+V Q +++Y+++ +NV +F E EAL F G+ Sbjct: 65 DFLKNEMAIKKSIGIVTQTISVYDDLNVYDNVMYFGGMYGLRGKKLKEYAREALNFVGIW 124 Query: 128 DRAKDKPSTFSGGMKRRLNIACAIMHRPKLIIMDEPTVGIDPQSRNHILESVKALNKLGS 187 D A+ P SGGM RRLNIAC I+H+PKLIIMDEPT GIDP+SR+++LES+K LNK G+ Sbjct: 125 DNARKFPKQLSGGMLRRLNIACGIVHKPKLIIMDEPTAGIDPKSRSNLLESIKELNKNGA 184 Query: 188 TVIYTSHYMEEVAAICDRVAIMDKGHIIACGTERELRERVAHEERIVVKAAHITPALIQE 247 T+IYTSHYMEE+ IC +AI+++G IIA G + EL+ A EE+I +K + + ++ E Sbjct: 185 TIIYTSHYMEEIERICSSIAIINEGRIIAKGDKEELKSLAAKEEKIKIKPSALNYTIVDE 244 Query: 248 LGKHPRINRAELNGDTVELYLPSSQSELQDILFIFAKHEGVIASLNIEEPDLETLFLSLT 307 + K + +N D +++ + + I+ + + + I+ P +ET+FL+LT Sbjct: 245 IKKIYGVKECSINADYIDIVSDKNSKNIAKIIDMIVGSGLEVLDVIIDRPSIETVFLALT 304 Query: 308 GRTL 311 GR L Sbjct: 305 GRNL 308 >CAC0169 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 310 Score = 263 bits (672), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 132/307 (42%), Positives = 196/307 (63%), Gaps = 1/307 (0%) Query: 8 LSDVVKRYDQKLTVDHVNFSIQEGEIFGLLGPNGAGKSTTISMICGLLKADGGDIVIDGL 67 L+++ K+Y V++++F I++GE+FGLLGPNGAGKST +SMI ++ GDI +D Sbjct: 4 LTNITKKYGDFTAVNNISFKIEDGEVFGLLGPNGAGKSTIVSMISTVISPTSGDITVDNK 63 Query: 68 SVLSKPLEVKKRIGLVPQELALYENMTATENVSFFXXXXXXXXXXXXERVEEALAFTGLS 127 + KP E+KK +G+VPQ++ALYE+++A +N+ FF ERV E L L Sbjct: 64 LLRQKPTEIKKVMGIVPQDIALYESLSAKDNLEFFGCLYGLNGKELKERVNEVLKIIELE 123 Query: 128 DRAKDKPSTFSGGMKRRLNIACAIMHRPKLIIMDEPTVGIDPQSRNHILESVKALNK-LG 186 D+ FSGGMKRR+NI A+M+ PKL+I+DEPTVGIDPQSRNHILE+VK LNK G Sbjct: 124 DKKDQAVEEFSGGMKRRVNIGVALMNNPKLLILDEPTVGIDPQSRNHILETVKKLNKERG 183 Query: 187 STVIYTSHYMEEVAAICDRVAIMDKGHIIACGTERELRERVAHEERIVVKAAHITPALIQ 246 TVIYTSHYMEEV +C R+AI+D G +IA GT+ EL+E+ ++ + V ++ + Sbjct: 184 MTVIYTSHYMEEVEYLCKRIAIVDHGKLIALGTKDELKEKSKAKDTLTVIYSNGDKGALD 243 Query: 247 ELGKHPRINRAELNGDTVELYLPSSQSELQDILFIFAKHEGVIASLNIEEPDLETLFLSL 306 ++ I ++ + + + + + + DI+ + S EE +LE++FL + Sbjct: 244 KIKSINGIENVSISNNQISMLVDQHKRNIIDIVEDVRNLGVKLTSFKYEEVNLESIFLQI 303 Query: 307 TGRTLRD 313 TG++LRD Sbjct: 304 TGKSLRD 310 >SPy0744 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 307 Score = 252 bits (644), Expect = 5e-67, Method: Compositional matrix adjust. Identities = 143/315 (45%), Positives = 196/315 (62%), Gaps = 12/315 (3%) Query: 3 MAFAVLSDVVKRY-DQKLTVDHVNFSIQEGEIFGLLGPNGAGKSTTISMICGLLKADGGD 61 M+F L++VVK Y + K V+ V+ SI+ G I+GLLGPNGAGKST I++I GL+ G Sbjct: 1 MSFVQLTNVVKSYKNGKKAVNDVSLSIEAGNIYGLLGPNGAGKSTLINLILGLIPLSSGK 60 Query: 62 IVIDGLSVLSKPL-EVKKRIGLVPQELALYENMTATENVSFFXXXXXXXXXXXXERVEEA 120 I + G S K + ++ +IG VPQ++A+Y ++TA ENV F ++V ++ Sbjct: 61 ITVLGQS--QKTIRKISSQIGYVPQDIAVYPDLTAYENVELFGSLYGLKGAQLKKQVLKS 118 Query: 121 LAFTGLSDRAKDKPSTFSGGMKRRLNIACAIMHRPKLIIMDEPTVGIDPQSRNHILESVK 180 L F GL +AK PS FSGGMKRRLNIACA++H PKLII DEPTVGIDPQSRNHILES++ Sbjct: 119 LEFVGLHSQAKQFPSQFSGGMKRRLNIACALVHSPKLIIFDEPTVGIDPQSRNHILESIR 178 Query: 181 ALNKLGSTVIYTSHYMEEVAAICDRVAIMDKGHIIACGTERELRERVAHE--ERIVVKAA 238 LNK G+TVIYT+HYMEEV A+CD + IMD G +I G + EL +R +I+V Sbjct: 179 LLNKEGATVIYTTHYMEEVEALCDYIFIMDHGQVIEEGPKFELEKRYVANLANQIIVT-- 236 Query: 239 HITPALIQELGKHPRINRAELNGDTVELYLPSSQSELQDILFIFAKHEGVIASLNIEEPD 298 +T + EL P + E D +L L S++ ++ + + + + Sbjct: 237 -LTDSRHLELADKPDWSLIE---DGEKLMLKIDNSDMTSVVHQLTQANITFSEIRHNHLN 292 Query: 299 LETLFLSLTGRTLRD 313 LE +FL LTG+ LRD Sbjct: 293 LEEIFLHLTGKKLRD 307 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.136 0.382 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 21,190,846 Number of extensions: 808725 Number of successful extensions: 9457 Number of sequences better than 1.0e-05: 2135 Number of HSP's gapped: 6249 Number of HSP's successfully gapped: 2361 Length of query: 313 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 207 Effective length of database: 26,153,027 Effective search space: 5413676589 Effective search space used: 5413676589 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 116 (49.3 bits)