BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0119.0008.p (615 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH0815 [V] COG1132 ABC-type multidrug transport system, ATPase a... 628 e-179 BS_yfiC [V] COG1132 ABC-type multidrug transport system, ATPase ... 620 e-177 TM0288 [V] COG1132 ABC-type multidrug transport system, ATPase a... 451 e-126 CAC2392 [V] COG1132 ABC-type multidrug transport system, ATPase ... 396 e-110 lin0617 [V] COG1132 ABC-type multidrug transport system, ATPase ... 384 e-106 >BH0815 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 611 Score = 628 bits (1619), Expect = e-179, Method: Compositional matrix adjust. Identities = 319/617 (51%), Positives = 417/617 (67%), Gaps = 12/617 (1%) Query: 1 MFKALLEPFRHPRLNVGLGDAASFGSPGGRKPKAKAKDWSATLRRIWSYXXXXXXXXXXX 60 M L EPFR+ ++ + + G K K + S TLRRIW+Y Sbjct: 1 MANPLTEPFRYRKIPIN-------ETEGSEKKKVRPAQASKTLRRIWTYLVNYRGRLLLV 53 Query: 61 XXXXXXXXXXXXXXPYLISRAVDHYL-EGDGGRTWGIFLITLAVVYLLNSLTSWLQNIWM 119 P++I A+DHYL EGD + + +I L +Y + SL+ WLQ +WM Sbjct: 54 FLAVLLSSVLGLLGPFVIGMAIDHYLVEGDTSSLFKV-MIGLLAIYAVYSLSMWLQQVWM 112 Query: 120 IEIAQETVYRMRTDLFAHLHRLPISFFNRRQQGEIMSRLTNDIENISSTLNSSAIQIFXX 179 I IAQ+TVY +R+DLF H HRLPI FF+++Q GE+MSR+TNDIENIS+TLNSS I+IF Sbjct: 113 IGIAQQTVYSIRSDLFHHFHRLPIPFFDKKQHGELMSRMTNDIENISNTLNSSVIKIFSS 172 Query: 180 XXXXXXXXXXMXXXXXXXXXXTFIVVPLMILGMRWITRRTGPLFKERQRNMGELNGFIEE 239 M T VVPLM+ G++WITRRT FK++Q+ +G+LNG+IEE Sbjct: 173 VLTLVGIMIVMLWLSPLMTVITMTVVPLMVFGLKWITRRTAVFFKQQQKALGDLNGYIEE 232 Query: 240 TLSGQRIIKAFSQEERVISGFRERNARIMLSGYWAQAISGFIPKLMNGLNNLSFAIVAGV 299 T+SGQ +I+AFS+E I+ F E+N + + +WAQ +GFIPK+MN LN+L+FA++AGV Sbjct: 233 TVSGQSVIQAFSREGAAIATFSEKNRELKTTSFWAQTYTGFIPKVMNVLNSLNFAVIAGV 292 Query: 300 GGLLAIRGLVTVGVIIAFVEYTRQFTRPLNDLANQWNTLLSAIAGAERVFEVLXXXXXXX 359 GG+LA+RG +T+G+I+ F EY RQFTRPLNDLANQ+N LL+AIAGAERVF++L Sbjct: 293 GGILAMRGSITIGIIVIFAEYARQFTRPLNDLANQFNMLLAAIAGAERVFDILDEQEERH 352 Query: 360 XXXXXVSLDHVEGTVKFSGVSFSYDGGADTLQDISFEAKPGEMIALVGPTGAGKTTLIGL 419 + ++G V F VSFSY+ TL ++SF PGE +AL+GPTGAGKTT+I L Sbjct: 353 HDQTK-QVKSIKGEVSFEQVSFSYEQKT-TLNNLSFHVNPGETVALIGPTGAGKTTIIRL 410 Query: 420 LSRFYDPDKGSITLDGXXXXXXXXXXXXXHMAFVLQDSFLFKGTIRDNIRYGRLDASDEE 479 LSRFY+ D G+I +DG H+AFVLQ+SFLF+GTIR+NIRYGRL+A+DEE Sbjct: 411 LSRFYEWDGGAIYVDGEDVTTWDRESYRRHLAFVLQESFLFQGTIRENIRYGRLEATDEE 470 Query: 480 VEAAAKLANAHSFIMRMKGGYERMLSVDGSGISQGQKQLLAIARAILANPSMLVLDEATS 539 VEAAAK+ANAHSFIMR+ Y+ +L DGSGISQGQKQLL+IARA++ANPS+L+LDEATS Sbjct: 471 VEAAAKMANAHSFIMRLPDQYDTVLDSDGSGISQGQKQLLSIARAMIANPSILILDEATS 530 Query: 540 SIDTVTEIKIQEGLQTLMKGRTSFVIAHRLGTIRAADRILVXXXXXXXXXXSHEELLQEG 599 +IDT+TE+ IQE L LM GRTSFVIAHRL TI+ AD ILV SHEEL+ + Sbjct: 531 NIDTITELNIQEALHRLMNGRTSFVIAHRLNTIQHADVILVLEKGTLVEQGSHEELMAKK 590 Query: 600 GLYSELV-RGSSDSAAG 615 G+Y +++ RG A G Sbjct: 591 GVYYDMIDRGQQTLAEG 607 >BS_yfiC [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 285 Score = 620 bits (1599), Expect = e-177, Method: Compositional matrix adjust. Identities = 0/605 (0%), Positives = 0/605 (0%), Gaps = 8/605 (1%) Query: 1 MFKALLEPFRHPRLNVGLGDAASFGSPGGRKPKAKAKDWSATLRRIWSYXXXXXXXXXXX 60 M+ A + + L+ Sbjct: 1 MWGADYRRYGCNLHLFVWIS--------LLGYCSHPVLSPFFLQGFIFMSQSTSVLRRNG 52 Query: 61 XXXXXXXXXXXXXXPYLISRAVDHYLEGDGGRTWGIFLITLAVVYLLNSLTSWLQNIWMI 120 + + + I L L + MI Sbjct: 53 FTFKQFFVAHDRCAMKVGTDGILLGAWAPVAGVKRCLDIGAGSGLLALMLAQRTDDSVMI 112 Query: 121 EIAQETVYRMRTDLFAHLHRLPISFFNRRQQGEIMSRLTNDIENISSTLNSSAIQIFXXX 180 + + N + N Q Sbjct: 113 DAVELESEAAAQAQENINQSPWAERINVHTADIQQWITQQTVRFDLIISNPPYYQQGVEC 172 Query: 181 XXXXXXXXXMXXXXXXXXXXTFIVVPLMILGMRWITRRTGPLFKERQRNMGELNGFIEET 240 T + G + + + T Sbjct: 173 STPQREQARYTTTLDHPSLLTCAAECITEEGFFCVVLPEQIGNGFTELALSMGWHLRLRT 232 Query: 241 LSGQRIIKAFSQEERVISGFRERNARIMLSGYWAQAISGFIPKLMNGLNNLSFAIVAGVG 300 Sbjct: 233 292 Query: 301 GLLAIRGLVTVGVIIAFVEYTRQFTRPLNDLANQWNTLLSAIAGAERVFEVLXXXXXXXX 360 Sbjct: 293 352 Query: 361 XXXXVSLDHVEGTVKFSGVSFSYDGGADTLQDISFEAKPGEMIALVGPTGAGKTTLIGLL 420 Sbjct: 353 412 Query: 421 SRFYDPDKGSITLDGXXXXXXXXXXXXXHMAFVLQDSFLFKGTIRDNIRYGRLDASDEEV 480 Sbjct: 413 472 Query: 481 EAAAKLANAHSFIMRMKGGYERMLSVDGSGISQGQKQLLAIARAILANPSMLVLDEATSS 540 Sbjct: 473 532 Query: 541 IDTVTEIKIQEGLQTLMKGRTSFVIAHRLGTIRAADRILVXXXXXXXXXXSHEELLQEGG 600 Sbjct: 533 592 Query: 601 LYSEL 605 Sbjct: 593 597 >TM0288 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 598 Score = 451 bits (1159), Expect = e-126, Method: Compositional matrix adjust. Identities = 235/573 (41%), Positives = 337/573 (58%), Gaps = 1/573 (0%) Query: 33 KAKAKDWSATLRRIWSYXXXXXXXXXXXXXXXXXXXXXXXXXPYLISRAVDHYLEGDGGR 92 K K+ +ATLRR+ Y PYLI + +D Sbjct: 15 KPALKNPTATLRRLLGYLRPHTFTLIMVFVFVTVSSILGVLSPYLIGKTIDVVFVPRRFD 74 Query: 93 TWGIFLITLAVVYLLNSLTSWLQNIWMIEIAQETVYRMRTDLFAHLHRLPISFFNRRQQG 152 +++ L +Y L SL WLQ M+ ++Q+ V+R+R +LF L R+P+ FF+R G Sbjct: 75 LLPRYMLILGTIYALTSLLFWLQGKIMLTLSQDVVFRLRKELFEKLQRVPVGFFDRTPHG 134 Query: 153 EIMSRLTNDIENISSTLNSSAIQIFXXXXXXXXXXXXMXXXXXXXXXXTFIVVPLMILGM 212 +I+SR+ ND++NI++ L +S IQ F M T +VPL +L Sbjct: 135 DIISRVINDVDNINNVLGNSIIQFFSGIVTLAGAVIMMFRVNVILSLVTLSIVPLTVLIT 194 Query: 213 RWITRRTGPLFKERQRNMGELNGFIEETLSGQRIIKAFSQEERVISGFRERNARIMLSGY 272 + ++ +T F E QR +G+LNG IEE +SG +IK F++EE+ + F N + G Sbjct: 195 QIVSSQTRKYFYENQRVLGQLNGIIEEDISGLTVIKLFTREEKEMEKFDRVNESLRKVGT 254 Query: 273 WAQAISGFIPKLMNGLNNLSFAIVAGVGGLLAIRGLVTVGVIIAFVEYTRQFTRPLNDLA 332 AQ SG +P LMN +NNL FA+++G GG LA++ ++TVG I F+ Y+RQFTRPLN+L+ Sbjct: 255 KAQIFSGVLPPLMNMVNNLGFALISGFGGWLALKDIITVGTIATFIGYSRQFTRPLNELS 314 Query: 333 NQWNTLLSAIAGAERVFEVLXXXXXXXXXXXXVSLDHVEGTVKFSGVSFSYDGGADTLQD 392 NQ+N + A+A AER+FE+L V L V G ++F V FSYD L+D Sbjct: 315 NQFNMIQMALASAERIFEILDLEEEKDDPDA-VELREVRGEIEFKNVWFSYDKKKPVLKD 373 Query: 393 ISFEAKPGEMIALVGPTGAGKTTLIGLLSRFYDPDKGSITLDGXXXXXXXXXXXXXHMAF 452 I+F KPG+ +ALVGPTG+GKTT++ LL RFYD D+G I +DG + Sbjct: 374 ITFHIKPGQKVALVGPTGSGKTTIVNLLMRFYDVDRGQILVDGIDIRKIKRSSLRSSIGI 433 Query: 453 VLQDSFLFKGTIRDNIRYGRLDASDEEVEAAAKLANAHSFIMRMKGGYERMLSVDGSGIS 512 VLQD+ LF T+++N++YG A+DEE++ AAKL ++ FI + GYE +L+ +G +S Sbjct: 434 VLQDTILFSTTVKENLKYGNPGATDEEIKEAAKLTHSDHFIKHLPEGYETVLTDNGEDLS 493 Query: 513 QGQKQLLAIARAILANPSMLVLDEATSSIDTVTEIKIQEGLQTLMKGRTSFVIAHRLGTI 572 QGQ+QLLAI RA LANP +L+LDEATS++DT TE IQ + LM+G+TS +IAHRL TI Sbjct: 494 QGQRQLLAITRAFLANPKILILDEATSNVDTKTEKSIQAAMWKLMEGKTSIIIAHRLNTI 553 Query: 573 RAADRILVXXXXXXXXXXSHEELLQEGGLYSEL 605 + AD I+V H+EL+Q+ G Y EL Sbjct: 554 KNADLIIVLRDGEIVEMGKHDELIQKRGFYYEL 586 >CAC2392 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 579 Score = 396 bits (1017), Expect = e-110, Method: Compositional matrix adjust. Identities = 214/543 (39%), Positives = 309/543 (56%), Gaps = 4/543 (0%) Query: 75 PYLISRAVDHYLEGDGGRTWGIFL---ITLAVVYLLNSLTSWLQNIWMIEIAQETVYRMR 131 P ++ + +D+ ++ G + L I LA VYL++S+ +WL +A TV +R Sbjct: 38 PLIVGKGIDN-IKSQGKVDFNNLLKIIIVLAAVYLISSIFTWLFTAVANILAYNTVRDLR 96 Query: 132 TDLFAHLHRLPISFFNRRQQGEIMSRLTNDIENISSTLNSSAIQIFXXXXXXXXXXXXMX 191 + + + LP+ +F+ G+IMSRLTND++ IS L Q F M Sbjct: 97 NEALSKISTLPLKYFDVNPHGDIMSRLTNDMDAISDGLFQGITQFFPAIVTIISSILLML 156 Query: 192 XXXXXXXXXTFIVVPLMILGMRWITRRTGPLFKERQRNMGELNGFIEETLSGQRIIKAFS 251 ++ PL +IT+R+ +FK++Q +GELNG+IEE + ++I+K F Sbjct: 157 SLSIKLTGIIILMTPLCFFIASFITKRSNKMFKQQQNTVGELNGYIEEIIGNEKIVKLFG 216 Query: 252 QEERVISGFRERNARIMLSGYWAQAISGFIPKLMNGLNNLSFAIVAGVGGLLAIRGLVTV 311 E+R F E N+R+ G AQ S +NN+++ +V VGGLLA+ +++ Sbjct: 217 YEKRAEKKFSEINSRLYNCGQLAQFYSSLTNPSTRFVNNITYVLVGAVGGLLAVLSGLSI 276 Query: 312 GVIIAFVEYTRQFTRPLNDLANQWNTLLSAIAGAERVFEVLXXXXXXXXXXXXVSLDHVE 371 G I +F+ Y+ QF++P+N++ L +A A AERVF +L +H E Sbjct: 277 GTISSFLTYSTQFSQPINNVTGVATQLQAAFASAERVFSILDEIPEKKDNEGAKKFEHCE 336 Query: 372 GTVKFSGVSFSYDGGADTLQDISFEAKPGEMIALVGPTGAGKTTLIGLLSRFYDPDKGSI 431 G + F+ VSFSY+ +++ S + K G IA+VGPTGAGKTT++ LL RFYD D G I Sbjct: 337 GNISFNNVSFSYNKKQPLIENFSVDIKKGSTIAIVGPTGAGKTTMVNLLMRFYDIDGGKI 396 Query: 432 TLDGXXXXXXXXXXXXXHMAFVLQDSFLFKGTIRDNIRYGRLDASDEEVEAAAKLANAHS 491 T+DG VLQD++LF+GTI++NI YG+ DAS EE+E+AAK A H+ Sbjct: 397 TIDGKDINKMKRNDVRGQFGMVLQDTWLFEGTIKENIAYGKPDASMEEIESAAKKAYIHN 456 Query: 492 FIMRMKGGYERMLSVDGSGISQGQKQLLAIARAILANPSMLVLDEATSSIDTVTEIKIQE 551 FI R+ GY+ ++ G +S+GQKQLL IAR +L NP ML+LDEATSS+DT TEIKIQ Sbjct: 457 FIKRLSDGYDTRITESGGNLSEGQKQLLTIARVMLINPPMLILDEATSSVDTRTEIKIQN 516 Query: 552 GLQTLMKGRTSFVIAHRLGTIRAADRILVXXXXXXXXXXSHEELLQEGGLYSELVRGSSD 611 +M+GRTSFVIAHRL TI+ AD ILV HEEL+ GLY E+ Sbjct: 517 AFLKMMEGRTSFVIAHRLSTIKDADLILVMKNGHIVERGKHEELVNSEGLYREIYESQFK 576 Query: 612 SAA 614 +A Sbjct: 577 NAV 579 >lin0617 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 605 Score = 384 bits (985), Expect = e-106, Method: Compositional matrix adjust. Identities = 228/580 (39%), Positives = 316/580 (54%), Gaps = 9/580 (1%) Query: 34 AKAKDWSATLRRIWSYXXXXXXXXXXXXXXXXXXXXXXXXXPYLISRAVDHYLEG----- 88 AK K++ TL R+ Y P + +A +G Sbjct: 16 AKPKNFKQTLFRLLGYMKPRSVAIIVVFIFAILSTIFNIFSPKELGKATTEIFKGVMSPE 75 Query: 89 --DGGRTWGIFLITLAVVYLLNSLTSWLQNIWMIEIAQETVYRMRTDLFAHLHRLPISFF 146 + + + I +I L V+YL +SL S++Q M +AQ TVY MR DL A + RLP+ ++ Sbjct: 76 GINNDKIFNILMIVL-VLYLGSSLFSFIQQYVMSSVAQRTVYDMRKDLKAKMARLPLKYY 134 Query: 147 NRRQQGEIMSRLTNDIENISSTLNSSAIQIFXXXXXXXXXXXXMXXXXXXXXXXTFIVVP 206 + R G+I+SR ND++NI++TL S Q M + VP Sbjct: 135 DTRSNGDILSRSVNDMDNIANTLQQSLTQAITAIVQMIGVLIMMLTISWQMTLIVLVTVP 194 Query: 207 LMILGMRWITRRTGPLFKERQRNMGELNGFIEETLSGQRIIKAFSQEERVISGFRERNAR 266 + I+ + I R+ F +QRN+G LN +EET GQ IIKAF QE++ + F E N Sbjct: 195 ISIILVAIIAGRSQRYFGAQQRNLGILNDTVEETYGGQTIIKAFGQEKKTLVKFDEVNED 254 Query: 267 IMLSGYWAQAISGFIPKLMNGLNNLSFAIVAGVGGLLAIRGLVTVGVIIAFVEYTRQFTR 326 + AQ ISG + +M + NL + V GG+ G + VG I +F +Y + FT+ Sbjct: 255 YFKAAKKAQFISGIMMPVMQFVGNLGYVGVCVAGGIFVTNGTLQVGDIQSFTQYVQLFTQ 314 Query: 327 PLNDLANQWNTLLSAIAGAERVFEVLXXXXXXXXXXXXVS-LDHVEGTVKFSGVSFSYDG 385 P++ +AN N + S IA AERVFE++ V+ + E ++ F V F Y Sbjct: 315 PISSVANIANIIQSTIASAERVFEMMDEEEEKDEIPANVNQVAGEEHSIVFDHVKFGYTP 374 Query: 386 GADTLQDISFEAKPGEMIALVGPTGAGKTTLIGLLSRFYDPDKGSITLDGXXXXXXXXXX 445 + D++ + G+M+A+VGPTGAGKTT+I LL RFYD D G I + G Sbjct: 375 DKPLMTDLNIHVEEGQMVAIVGPTGAGKTTIINLLMRFYDVDGGEIRMRGIDTRDMTKDA 434 Query: 446 XXXHMAFVLQDSFLFKGTIRDNIRYGRLDASDEEVEAAAKLANAHSFIMRMKGGYERMLS 505 VLQD++LF GTI DNI YGR A+ +EV AAK A A FI R+ GY+ +L+ Sbjct: 435 VREKFGMVLQDTWLFNGTIADNIAYGREGATKDEVIGAAKAAYADDFIRRLPNGYDTILN 494 Query: 506 VDGSGISQGQKQLLAIARAILANPSMLVLDEATSSIDTVTEIKIQEGLQTLMKGRTSFVI 565 +GS ISQGQKQLL IARAIL++PS+L+LDEATSS+DT TE+ IQ + LM+GRTSFVI Sbjct: 495 EEGSNISQGQKQLLTIARAILSDPSILILDEATSSVDTRTELNIQLAMGNLMEGRTSFVI 554 Query: 566 AHRLGTIRAADRILVXXXXXXXXXXSHEELLQEGGLYSEL 605 AHRL TIR AD ILV +H+ELL G Y++L Sbjct: 555 AHRLSTIRDADLILVMNHGSVIEQGTHQELLDAKGFYADL 594 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.322 0.138 0.398 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 36,887,392 Number of extensions: 1309453 Number of successful extensions: 18997 Number of sequences better than 1.0e-05: 1452 Number of HSP's gapped: 17476 Number of HSP's successfully gapped: 1484 Length of query: 615 Length of database: 38,378,431 Length adjustment: 112 Effective length of query: 503 Effective length of database: 25,461,023 Effective search space: 12806894569 Effective search space used: 12806894569 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 119 (50.4 bits)