BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0119.0007.p (581 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_yfiB [V] COG1132 ABC-type multidrug transport system, ATPase ... 563 e-160 TM0287 [V] COG1132 ABC-type multidrug transport system, ATPase a... 426 e-119 CAC2393 [V] COG1132 ABC-type multidrug transport system, ATPase ... 384 e-106 lin0616 [V] COG1132 ABC-type multidrug transport system, ATPase ... 344 2e-94 Cgl0940 [V] COG1132 ABC-type multidrug transport system, ATPase ... 316 6e-86 >BS_yfiB [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 160 Score = 563 bits (1450), Expect = e-160, Method: Compositional matrix adjust. Identities = 0/574 (0%), Positives = 0/574 (0%), Gaps = 6/574 (1%) Query: 1 MNIIFSYLKTYRXXXXXXXXXXXXXXXXELSQPLLISRIIDDGIRAQDNRIVWLWGGVLV 60 M + E + + + Sbjct: 1 MIKHLVAPLVFTSLILTGCQSPQGKFTPEQVAAMQSYGFTESAGDWSLGLSDAILFAKND 60 Query: 61 VSAVLAFIAGVLSSFFASHASQGFAFDLRDQLYEKVQSFTYAVFSRFTTSSLITRLTADV 120 + + + ++ + + S + + Sbjct: 61 YKLLPESQQQIQTMAAKLASTGLTHARMDGHTDNYGEDSYNEGLSLKRANVVADAWAMGG 120 Query: 121 SQLQDTIFMGLRFMTRVPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXWVMKKASVL 180 Sbjct: 121 180 Query: 181 FRSVQNRLDGVNSVIQENLTGIRLIRVFVRMNHEIARFAAFSGELMKSTVAALRLTETSA 240 Sbjct: 181 240 Query: 241 PLIMLIVNAGIMLVLWFGRIEISTGEATLGQTVAVINYSLRTIGALSALSWIMATFSRAR 300 Sbjct: 241 300 Query: 301 ASSQRIQEVMSADELEAKEMAAVTAREIAPIRGKVEFRQVSFRYPQSDIAVLEDITFKVQ 360 Sbjct: 301 ----- 355 Query: 361 PGDRVAIMGATGSGKSSLVGLIPRLYEQSSGDILVDGIPGAEMEISRLRGAIGYVPQEVL 420 Sbjct: 356 415 Query: 421 LFTGSVRENIAWGHPQATQDEIEQAAMAAQIHETVQELPNGYDTMLGQRGVNLSGGQKQR 480 Sbjct: 416 475 Query: 481 LTIARALVRKPAVLILDDSTSALDAVTESRLLAELKGMSCTTFLITQKISSTVSADLILL 540 Sbjct: 476 535 Query: 541 LDEGRLIAQGTHEELMERSELYRKINESQH-REG 573 Sbjct: 536 569 >TM0287 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 577 Score = 426 bits (1094), Expect = e-119, Method: Compositional matrix adjust. Identities = 235/578 (40%), Positives = 339/578 (58%), Gaps = 5/578 (0%) Query: 1 MNIIFSYLKTYRXXXXXXXXXXXXXXXXELSQPLLISRIIDDGIRAQDNRIVWLWGGVLV 60 M + YLK Y +LSQP L++RI+D+GI D +V G +++ Sbjct: 1 MKTLARYLKPYWIFAVLAPLFMVVEVICDLSQPTLLARIVDEGIARGDFSLVLKTGILML 60 Query: 61 VSAVLAFIAGVLSSFFASHASQGFAFDLRDQLYEKVQSFTYAVFSRFTTSSLITRLTADV 120 + A++ + G+ + FAS+ASQ F DLR L+ KV SF+ + +RF TSSLITRLT DV Sbjct: 61 IVALIGAVGGIGCTVFASYASQNFGADLRRDLFRKVLSFSISNVNRFHTSSLITRLTNDV 120 Query: 121 SQLQDTIFMGLRFMTRVPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXWVMKKASVL 180 +QLQ+ + M LR + R P W+ KK + L Sbjct: 121 TQLQNLVMMLLRIVVRAPLLFVGGIVMAVSINVKLSSVLIFLIPPIVLLFVWLTKKGNPL 180 Query: 181 FRSVQNRLDGVNSVIQENLTGIRLIRVFVRMNHEIARFAAFSGELMKSTVAALRLTETSA 240 FR +Q D VN V++ENL G+R++R F R +E F + L +S ++A L + Sbjct: 181 FRKIQESTDEVNRVVRENLLGVRVVRAFRREEYENENFRKANESLRRSIISAFSLIVFAL 240 Query: 241 PLIMLIVNAGIMLVLWFGRIEISTGEATLGQTVAVINYSLRTIGALSALSWIMATFSRAR 300 PL + IVN G++ VLWFG + + + +G +A NY ++ + +L + I+ RA Sbjct: 241 PLFIFIVNMGMIAVLWFGGVLVRNNQMEIGSIMAYTNYLMQIMFSLMMIGNILNFIVRAS 300 Query: 301 ASSQRIQEVMSADELEAKEMAAVTAREIAPIRGKVEFRQVSFRYPQSDIAVLEDITFKVQ 360 AS++R+ EV+ +E A E A A + + G V F V FRY ++ VL + F V+ Sbjct: 301 ASAKRVLEVL--NEKPAIEEAD-NALALPNVEGSVSFENVEFRYFENTDPVLSGVNFSVK 357 Query: 361 PGDRVAIMGATGSGKSSLVGLIPRLYEQSSGDILVDGIPGAEMEISRLRGAIGYVPQEVL 420 PG VA++G TGSGKS+L+ LIPRL + G + VD + +++ LRG I VPQE + Sbjct: 358 PGSLVAVLGETGSGKSTLMNLIPRLIDPERGRVEVDELDVRTVKLKDLRGHISAVPQETV 417 Query: 421 LFTGSVRENIAWGHPQATQDEIEQAAMAAQIHETVQELPNGYDTMLGQRGVNLSGGQKQR 480 LF+G+++EN+ WG AT DEI +AA AQIH+ + LP GYD+ + + G N SGGQKQR Sbjct: 418 LFSGTIKENLKWGREDATDDEIVEAAKIAQIHDFIISLPEGYDSRVERGGRNFSGGQKQR 477 Query: 481 LTIARALVRKPAVLILDDSTSALDAVTESRLLAELKGMS--CTTFLITQKISSTVSADLI 538 L+IARALV+KP VLILDD TS++D +TE R+L LK + CTTF+ITQKI + + AD I Sbjct: 478 LSIARALVKKPKVLILDDCTSSVDPITEKRILDGLKRYTKGCTTFIITQKIPTALLADKI 537 Query: 539 LLLDEGRLIAQGTHEELMERSELYRKINESQHREGVQH 576 L+L EG++ GTH+EL+E + YR+I ESQ GV + Sbjct: 538 LVLHEGKVAGFGTHKELLEHCKPYREIYESQFGNGVMN 575 >CAC2393 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 577 Score = 384 bits (985), Expect = e-106, Method: Compositional matrix adjust. Identities = 206/547 (37%), Positives = 320/547 (58%), Gaps = 10/547 (1%) Query: 29 ELSQPLLISRIIDDGIRAQDNRIVWLWGGVLVVSAVLAFIAGVLSSFFASHASQGFAFDL 88 E+S P ++ I D GI +DN + G ++++ A+ +A +FAS ASQGF L Sbjct: 29 EISIPTIMVLITDKGISTKDNGYIVKIGIIMILMAIFGVMASFTCQYFASIASQGFGTIL 88 Query: 89 RDQLYEKVQSFTYAVFSRFTTSSLITRLTADVSQLQDTIFMGLRFMTRVPXXXXXXXXXX 148 R++L++K+ +F+Y F T+SLI R+T DV+QLQ + M +R RVP Sbjct: 89 RNELFKKIGTFSYNEIDEFGTASLINRVTNDVNQLQLALAMFIRLAIRVPFLCIGGIIMA 148 Query: 149 XXXXXXXXXXXXXXXXXXXXXXXWVMKKASVLFRSVQNRLDGVNSVIQENLTGIRLIRVF 208 +M K+ L++ VQ +LD + +++ENL+GIR+IR F Sbjct: 149 MFLDVKLSTIMYLSIPVFAFVVYLIMSKSLPLYKVVQRKLDSLALILRENLSGIRVIRAF 208 Query: 209 VRMNHEIARFAAFSGELMKSTVAALRLTETSAPLIMLIVNAGIMLVLWFGRIEISTGEAT 268 +M E RF + EL + +++ PL +I+N ++ +LWFG ++ G T Sbjct: 209 SKMEREKERFKNSNEELTNEVIRVGKISALMNPLTSIIMNFSVLAILWFGGTRVNGGAIT 268 Query: 269 LGQTVAVINYSLRTIGALSALSWIMATFSRARASSQRIQEV----MSADELEAKEMAAVT 324 G+ +A INY+ + AL ++ ++ F++A AS+ R++EV +S + L+ KE Sbjct: 269 RGKIIAYINYTNLVLSALIIVANLIVIFTKAAASAARVEEVFNTEISINYLDNKEFKKED 328 Query: 325 AREIAPIRGKVEFRQVSFRYPQSDIAVLEDITFKVQPGDRVAIMGATGSGKSSLVGLIPR 384 R+ + I+ F V+F Y S + DI+F+++ G V I+G TG+GK++L+ LIPR Sbjct: 329 IRDASLIK----FDNVAFSYKNSKEYAISDISFEIKKGQTVGIIGGTGAGKTTLINLIPR 384 Query: 385 LYEQSSGDILVDGIPGAEMEISRLRGAIGYVPQEVLLFTGSVRENIAWGHPQATQDEIEQ 444 LY+ + G + ++GI + L IG VPQ+ +LF+G++ ENI+WG A+ +EI+ Sbjct: 385 LYDTAKGQVFINGIDVKNYPKTVLEEKIGVVPQKAILFSGTIFENISWGRENASLEEIKD 444 Query: 445 AAMAAQIHETVQELPNGYDTMLGQRGVNLSGGQKQRLTIARALVRKPAVLILDDSTSALD 504 AA E +++LP YDT + Q G N SGGQKQRLTIARALV+KP +LILDDS SALD Sbjct: 445 AAKIGMASEFIEKLPKKYDTNISQGGANFSGGQKQRLTIARALVKKPEILILDDSLSALD 504 Query: 505 AVTESRLLAELKGMS--CTTFLITQKISSTVSADLILLLDEGRLIAQGTHEELMERSELY 562 T++ L ELK S T ++TQ+IS+ ADLI++LD+G++ GTH EL+E SE+Y Sbjct: 505 YATDAALRQELKENSKDMTVLMVTQRISTIKDADLIIVLDDGKVAGVGTHNELLEESEVY 564 Query: 563 RKINESQ 569 ++I SQ Sbjct: 565 KEICNSQ 571 >lin0616 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 570 Score = 344 bits (883), Expect = 2e-94, Method: Compositional matrix adjust. Identities = 199/546 (36%), Positives = 318/546 (58%), Gaps = 6/546 (1%) Query: 29 ELSQPLLISRIIDDGIRAQDNRIVWLWGGVLVVSAVLAFIAGVLSSFFASHASQGFAFDL 88 +L P L+S IID G+ D +W G +++ + + I V+ + AS S GF DL Sbjct: 25 QLFLPTLMSNIIDKGVVKGDTDYIWSTGMQMLLISFASVILSVIVVYLASRISMGFGKDL 84 Query: 89 RDQLYEKVQSFTYAVFSRFTTSSLITRLTADVSQLQDTIFMGLRFMTRVPXXXXXXXXXX 148 RD+++ KV+ F+ F + TSSLITR T DV Q+Q+ ++M +R M P Sbjct: 85 RDKIFTKVEDFSLQEFDKVGTSSLITRTTNDVVQIQNVLYMMMRLMVMAPIMLLGGIIMA 144 Query: 149 XXXXXXXXXXXXXXXXXXXXXXXWVMKKASVLFRSVQNRLDGVNSVIQENLTGIRLIRVF 208 + KA +F+S+Q ++D +N VI+E LTGIR++R F Sbjct: 145 VGRDAKLSLIFVVVLPLLLLLVVILGGKAMPMFKSLQKKMDKLNRVIREGLTGIRVVRSF 204 Query: 209 VRMNHEIARFAAFSGELMKSTVAALRLTETSAPLIMLIVNAGIMLVLWFGRIEISTGEAT 268 R E+ +F + + + + RL +PL+ML++N + ++W G I I G+ Sbjct: 205 NRNEDELEKFEEANADYATTAIKVNRLLSLMSPLMMLLMNLTSIAIVWIGSIFIGNGDME 264 Query: 269 LGQTVAVINYSLRTIGALSALSWIMATFSRARASSQRIQEVMSADELEAKEMAAVTAREI 328 +G +A I Y+++ + + LS + RA AS++RI EV+ +++A+ + + Sbjct: 265 VGDLMAFIQYAMQIMMSFMMLSAVFIMIPRAGASAERINEVL---DMKAEILNPENPKTS 321 Query: 329 APIRGKVEFRQVSFRYPQSDIAVLEDITFKVQPGDRVAIMGATGSGKSSLVGLIPRLYEQ 388 P K+ F V+FRY ++ V+EDITF+ + G+ +AI+G+TG+GKS+L+ +IPR Y+ Sbjct: 322 TP-PAKLSFEHVTFRYEGAEKPVIEDITFEAKAGETIAIIGSTGAGKSTLINMIPRFYDV 380 Query: 389 SSGDILVDGIPGAEMEISRLRGAIGYVPQEVLLFTGSVRENIAWGHPQATQDEIEQAAMA 448 SG + ++GI EM+ S+LR IG VPQ+ +LFTG++ N+ +G AT +EI A Sbjct: 381 ESGVVKINGIDVREMDQSKLRQKIGLVPQKAVLFTGTIASNMRYGKEDATDEEIWAALRT 440 Query: 449 AQIHETVQELPNGYDTMLGQRGVNLSGGQKQRLTIARALVRKPAVLILDDSTSALDAVTE 508 AQ V +L NG + + Q G N SGGQKQRL+IAR+L+RKP + I DDS SALD T+ Sbjct: 441 AQAENFVSKLANGLGSRVEQGGNNFSGGQKQRLSIARSLIRKPEIYIFDDSFSALDFKTD 500 Query: 509 SRLLAELKGMS--CTTFLITQKISSTVSADLILLLDEGRLIAQGTHEELMERSELYRKIN 566 ++L LK + T ++ Q+I+S V++D I++L+EG++ GTHEEL E +++Y++I Sbjct: 501 AKLREALKAETTEAVTLIVAQRITSVVNSDQIIVLNEGKIAGIGTHEELKESNKIYQEIM 560 Query: 567 ESQHRE 572 +SQ E Sbjct: 561 KSQLSE 566 >Cgl0940 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 577 Score = 316 bits (810), Expect = 6e-86, Method: Compositional matrix adjust. Identities = 183/546 (33%), Positives = 290/546 (53%), Gaps = 7/546 (1%) Query: 33 PLLISRIIDDGIRAQDNRIVWLWGGVLVVSAVLAFIAGVLSSFFASHASQGFAFDLRDQL 92 P L + IID+G+ D +W GG+++ ++ + +F S S DLR + Sbjct: 35 PTLNADIIDNGVVTGDIGYIWHTGGIMLALTLVQVACAIAGVYFGSKLSMRVGRDLRSAI 94 Query: 93 YEKVQSFTYAVFSRFTTSSLITRLTADVSQLQDTIFMGLRFMTRVPXXXXXXXXXXXXXX 152 + KV +F+ +F SLITR T DV Q+Q + M M P Sbjct: 95 FGKVVNFSEREMGQFGAPSLITRNTNDVQQVQMLVQMTSTLMISAPMLAIGGIIMAVRQD 154 Query: 153 XXXXXXXXXXXXXXXXXXXWVMKKASVLFRSVQNRLDGVNSVIQENLTGIRLIRVFVRMN 212 ++ + LF+++Q R+D +N +I+E LTGIR+IR FVR + Sbjct: 155 LGLSWLMVVSIPVLIIVVALIIVRMVPLFQTMQKRIDRINQIIREQLTGIRVIRAFVRED 214 Query: 213 HEIARFAAFSGELMKSTVAALRLTETSAPLIMLIVNAGIMLVLWFGRIEISTGEATLGQT 272 E RF S ++ V L P +MLI+N + V+WFG ++ +GE +G Sbjct: 215 VERERFTTASKDVADIGVRTGNLMALMFPAVMLIMNLSAVAVIWFGAFQVESGETQIGTL 274 Query: 273 VAVINYSLRTIGALSALSWIMATFSRARASSQRIQEVM-SADELEAKEMAAVTAREIAPI 331 A + Y ++ + + +++ RA S+ RI EV+ + ++A E A + Sbjct: 275 FAFLQYIMQILMGVMMAAFMFVMVPRAAVSADRIGEVLETTPSVQAPETPAQPSTS---- 330 Query: 332 RGKVEFRQVSFRYPQSDIAVLEDITFKVQPGDRVAIMGATGSGKSSLVGLIPRLYEQSSG 391 G++ F +F YP +D VL +++F+V PG AI+G+TGSGK++L+GL+PRL++ + G Sbjct: 331 AGEIVFNNATFAYPGADDPVLNNVSFRVAPGSTTAIIGSTGSGKTTLIGLVPRLFDVTEG 390 Query: 392 DILVDGIPGAEMEISRLRGAIGYVPQEVLLFTGSVRENIAWGHPQATQDEIEQAAMAAQI 451 D+ VDG E E +L IG VPQ+ LF+G++ N+ +G+ AT+ ++ QA AQ Sbjct: 391 DVTVDGTDVREFEPLKLWDRIGLVPQKSFLFSGTIASNLRYGNEDATETQLWQALAIAQA 450 Query: 452 HETVQELPNGYDTMLGQRGVNLSGGQKQRLTIARALVRKPAVLILDDSTSALDAVTESRL 511 + V+E+P G D+ + Q G N+SGGQ+QRL IARAL+++P + I DDS SALD T++ L Sbjct: 451 ADFVREMPEGLDSEIAQGGTNVSGGQRQRLAIARALLKQPEIYIFDDSFSALDVSTDAAL 510 Query: 512 LAELKG--MSCTTFLITQKISSTVSADLILLLDEGRLIAQGTHEELMERSELYRKINESQ 569 L T ++ Q++S+ AD I++LD G ++ GTH L+ YR+I ESQ Sbjct: 511 RRALSTNLPDATKLIVAQRVSTIRDADQIVVLDNGEVVGIGTHTNLLNTCGTYREIVESQ 570 Query: 570 HREGVQ 575 Q Sbjct: 571 ETAQAQ 576 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.134 0.372 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 33,355,993 Number of extensions: 1235714 Number of successful extensions: 8871 Number of sequences better than 1.0e-05: 1940 Number of HSP's gapped: 6739 Number of HSP's successfully gapped: 2083 Length of query: 581 Length of database: 38,378,431 Length adjustment: 112 Effective length of query: 469 Effective length of database: 25,461,023 Effective search space: 11941219787 Effective search space used: 11941219787 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 119 (50.4 bits)