BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0115.0010.p (162 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC1007 [KR] COG0454 Histone acetyltransferase HPA2 and related ... 124 8e-29 Cj1715 [KR] COG0454 Histone acetyltransferase HPA2 and related a... 96 3e-20 SP1464 [KR] COG0454 Histone acetyltransferase HPA2 and related a... 80 1e-15 L182026 [KR] COG0454 Histone acetyltransferase HPA2 and related ... 66 2e-11 AGc4205 [O] COG1975 Xanthine and CO dehydrogenases maturation fa... 58 6e-09 >CAC1007 [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases Length = 174 Score = 124 bits (310), Expect = 8e-29, Method: Compositional matrix adjust. Identities = 54/150 (36%), Positives = 88/150 (58%) Query: 1 MELIAKCVQVMQAGGSDQWNESYPNQEVISEDVDNGTLYAYEEQGAIAGIIVLDEEQAEQ 60 +++I+ C++ M++ G QW+E YP+ ++I D+ Y ++ + ++E+Q + Sbjct: 23 IDIISNCIRYMKSQGIYQWDEFYPSSDIIENDIKRKDCYVLKDNERCVAYVAINEQQPPE 82 Query: 61 YDAIDWAEGQGPHLMMHRLAVHPEVQGKGIARKLIAFAEEHARSRGYTSIRLDTYAKNAR 120 Y IDW + L++HRL V PE QG+GIA+K++ F E+ A Y+SIRLD Y+ N + Sbjct: 83 YSQIDWLTHEKKILVIHRLCVQPEFQGRGIAKKILKFIEDLATKNNYSSIRLDAYSGNNK 142 Query: 121 ALALYPSLGYEYRGVVDFPGRTANFSVFEK 150 AL LY +L Y+ G P R F +EK Sbjct: 143 ALKLYSNLDYKKVGQFYLPVRDLPFYCYEK 172 >Cj1715 [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases Length = 176 Score = 95.9 bits (237), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 49/155 (31%), Positives = 80/155 (51%), Gaps = 2/155 (1%) Query: 1 MELIAKCVQVMQAGGSDQWNESYPNQEVISEDVDNGTLYAYEEQGAIAGIIVLDEE-QAE 59 +E+ + M+ QW+E+YPN+ V ED+ LY ++E I G I ++E+ + E Sbjct: 18 LEITKDALNAMKTMNFHQWDENYPNEIVFQEDIQAQELYVFKENDEILGFICINEKFKPE 77 Query: 60 QYDAIDWAEG-QGPHLMMHRLAVHPEVQGKGIARKLIAFAEEHARSRGYTSIRLDTYAKN 118 Y + + + +HRLAV +GKG+A+KL+ F E A S+R DT++KN Sbjct: 78 FYKQVIFNKNYDDKAFYLHRLAVKQNAKGKGVAQKLLNFCENFALENHKASLRADTHSKN 137 Query: 119 ARALALYPSLGYEYRGVVDFPGRTANFSVFEKVLT 153 +L+ L + + G D P F +EK+L Sbjct: 138 FPMNSLFKKLDFNFCGNFDIPNYQDPFLAYEKILN 172 >SP1464 [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases Length = 164 Score = 80.1 bits (196), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 46/153 (30%), Positives = 77/153 (50%), Gaps = 6/153 (3%) Query: 1 MELIAKCVQVMQAGGSDQWNESYPNQEVISEDVDNGTLYAYEEQGAIAGIIVLDEEQAEQ 60 M+++ + + GSDQW YPN +VI +D+ +G Y E+G + + + E Sbjct: 15 MQVMEDAKKCLADAGSDQWQNGYPNADVIIDDIISGQAYVALEEGELLAYAAVTKSPEEA 74 Query: 61 YDAI---DWAEGQGPHLMMHRLAVHPEVQGKGIARKLIAFAEEHARSRGYTSIRLDTYAK 117 Y+AI +W G+ +L+ HR+AV +VQGKG+A+ F E Y R DT+A+ Sbjct: 75 YEAIYEGNWQAGESEYLVFHRIAVAADVQGKGVAQ---TFLEGLIEGFDYLDFRSDTHAE 131 Query: 118 NARALALYPSLGYEYRGVVDFPGRTANFSVFEK 150 N ++ LG++ G + G + +K Sbjct: 132 NKVMQHIFEKLGFKQVGKMPVDGERLAYQKLKK 164 >L182026 [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases Length = 177 Score = 66.2 bits (160), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 33/116 (28%), Positives = 63/116 (54%), Gaps = 4/116 (3%) Query: 23 YPNQEVISEDVDNGTLY-AYEEQGAIAGIIVLDEEQAEQYDAIDWAEGQ-GPH--LMMHR 78 YP+ + + +D L+ Y+ ++G ++L+ + ++Y+ I W+ + P+ L++H Sbjct: 39 YPSIDTALKAIDLSQLFVCYDSNDIVSGTVILNNQSDKEYENITWSTPELDPNQILIIHT 98 Query: 79 LAVHPEVQGKGIARKLIAFAEEHARSRGYTSIRLDTYAKNARALALYPSLGYEYRG 134 L + P+ +GIA +I F ++ +S +IRLDT KN A LY + +RG Sbjct: 99 LVIDPKKLNQGIASAMINFIKDFGKSNSMVTIRLDTNFKNTPAQKLYEKHQFVFRG 154 >AGc4205 [O] COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Length = 248 Score = 58.2 bits (139), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 8/80 (10%), Positives = 15/80 (18%), Gaps = 6/80 (7%) Query: 76 MHRLAVHPEVQGKGIARKLIAFAEEHARSRGYTSIRLDTYAKNARALALYPSLGYEYRGV 135 LA ++ G + A S A+ + +L Sbjct: 91 GGGLAKGLKLLKPGPVFVMNADLFWIGERLNAVSNLRKL-AQFLDPARMDMALLCVDMDR 149 Query: 136 VD----FP-GRTANFSVFEK 150 A + Sbjct: 150 TTGHNGKRDFNLAGEGKLTR 169 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.315 0.133 0.387 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 12,804,263 Number of extensions: 503540 Number of successful extensions: 1105 Number of sequences better than 1.0e-05: 7 Number of HSP's gapped: 1110 Number of HSP's successfully gapped: 7 Length of query: 162 Length of database: 38,378,431 Length adjustment: 98 Effective length of query: 64 Effective length of database: 27,075,699 Effective search space: 1732844736 Effective search space used: 1732844736 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 111 (47.4 bits)