BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0112.0028.p (176 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMc04323 [KE] COG1167 Transcriptional regulators containing a DN... 90 1e-18 BMEI0626 [KE] COG1167 Transcriptional regulators containing a DN... 90 2e-18 AGc3654 [KE] COG1167 Transcriptional regulators containing a DNA... 89 4e-18 DR1588 [KE] COG1167 Transcriptional regulators containing a DNA-... 87 2e-17 RSc0985 [KE] COG1167 Transcriptional regulators containing a DNA... 83 2e-16 >SMc04323 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Length = 408 Score = 90.1 bits (222), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 48/157 (30%), Positives = 80/157 (50%), Gaps = 1/157 (0%) Query: 6 HVVYMKSFSKVIAPGFRIACVAAEGNILSRLIAAKSASDLGSPLLTQGAVLPFIARKYED 65 +Y SFSK +APG R+ + A ++ +L+ K A+DL S + Q A+ R +E+ Sbjct: 238 RTIYCGSFSKTLAPGLRVGWICAAEPVIRKLVLMKQAADLHSSTINQMAIATVAERGFEE 297 Query: 66 YXXXXXXXXXXXMEKAAGLLKQYAPPGVTWVLPEGGLNLWLQLPSASGIAQLHALAEQEG 125 + L++Y P GVTW PEGG+ +W+ LP S A+L A + Q Sbjct: 298 QVAKIHKAYRQRRDAMLSALEKYMPAGVTWTKPEGGMFIWVTLPKGSDGAELLAKSIQTA 357 Query: 126 -ISFLPGDVCYAGDLPSRHIRLCYSQMTEADMEQGLR 161 ++F+PG +A +RL +S + +++G+R Sbjct: 358 KVAFVPGRAFFADGSGENTLRLSFSCANDRMIDEGIR 394 >BMEI0626 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Length = 415 Score = 89.7 bits (221), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 49/172 (28%), Positives = 83/172 (48%), Gaps = 1/172 (0%) Query: 3 EDGHVVYMKSFSKVIAPGFRIACVAAEGNILSRLIAAKSASDLGSPLLTQGAVLPFIARK 62 E +Y SFSK +APG R+ V A ++ +L+ K A+DL S + Q A+ Sbjct: 241 EKTRTIYCGSFSKTLAPGLRVGYVVASKTVIRKLVLMKQAADLHSSTINQIAIQHVAVHG 300 Query: 63 YEDYXXXXXXXXXXXMEKAAGLLKQYAPPGVTWVLPEGGLNLWLQLPSA-SGIAQLHALA 121 ++ ++ L +Y P GV W PEGG+ +W+ LP G + L A Sbjct: 301 FDAQVAKLHGVYKHRRDRMLEALAKYMPEGVHWTKPEGGMFVWVTLPEGMDGASLLAASI 360 Query: 122 EQEGISFLPGDVCYAGDLPSRHIRLCYSQMTEADMEQGLRLFLILLDKHLRS 173 + E ++F+PG +A + +RL YS + +++G++ L+ H +S Sbjct: 361 DSEKVAFVPGKAFFADGTGANTLRLSYSCANDEMIDEGIKRLGRLIRAHTKS 412 >AGc3654 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Length = 301 Score = 88.6 bits (218), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 0/160 (0%), Positives = 0/160 (0%), Gaps = 1/160 (0%) Query: 3 EDGHVVYMKSFSKVIAPGFRIACVAAEGNILSRLIAAKSASDLGSPLLTQGAVLPFIARK 62 K + + A +L + + A R Sbjct: 235 ILVEREGQKKMVIGNKGAKIKTIGIEARKDMQEMFEAPVHLELWVKVKSGWADDERALRS 294 Query: 63 YEDYXXXXXXXXXXXMEKAAGLLKQYAPPGVTWVLPEGGLNLWLQLPSA-SGIAQLHALA 121 Sbjct: 295 354 Query: 122 EQEGISFLPGDVCYAGDLPSRHIRLCYSQMTEADMEQGLR 161 Sbjct: 355 394 >DR1588 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Length = 420 Score = 86.7 bits (213), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 52/165 (31%), Positives = 82/165 (49%), Gaps = 13/165 (7%) Query: 3 EDGHVVYMKSFSKVIAPGFRIACVAAEGNILSRLIAAKSASDLGSPLLTQGAV---LPFI 59 + HV+Y SFSK + PG R A V A ++++LI AK +DL +P L Q + LP + Sbjct: 252 DRNHVIYSSSFSKTLVPGLRDAWVEAAAPVITKLIQAKQGADLHTPTLNQMMITELLPLL 311 Query: 60 ARKYEDYXXXXXXXXXXXMEKAAGLLKQ---YAPPGVTWVLPEGGLNLWLQLPSASGIAQ 116 + E E+ A +L Q + P GVT+ P+GG+ LW+ LP Sbjct: 312 PAQIE-------TVKAAYRERGAHMLSQMDEFFPAGVTYTRPQGGMFLWVTLPEGVDTVA 364 Query: 117 LHALAEQEGISFLPGDVCYAGDLPSRHIRLCYSQMTEADMEQGLR 161 L A + ++++PG +A + +R+ YS T + QG+R Sbjct: 365 LLPRAVENKVAYVPGQPFFALGGGANTMRMSYSSATPEQITQGMR 409 >RSc0985 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Length = 406 Score = 83.2 bits (204), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 53/176 (30%), Positives = 84/176 (47%), Gaps = 2/176 (1%) Query: 1 MDEDGHVVYMKSFSKVIAPGFRIACVAAEGNILSRLIAAKSASDLGSPLLTQGAVLPFIA 60 ++ DG VVYM SFSK++APG R+ + A I +L+ AK ASDL +P TQ + Sbjct: 228 LNPDG-VVYMGSFSKILAPGMRLGYIIAPEPIHFKLVQAKQASDLHTPSFTQRVAYEVLK 286 Query: 61 RKYED-YXXXXXXXXXXXMEKAAGLLKQYAPPGVTWVLPEGGLNLWLQLPSASGIAQLHA 119 D + E L ++ P GV W PEGG+ +W+++P L Sbjct: 287 TGLLDTHIPSIRTLYGKQCETMLDALTRHMPAGVHWNRPEGGMFIWVEVPEGIDTMALLE 346 Query: 120 LAEQEGISFLPGDVCYAGDLPSRHIRLCYSQMTEADMEQGLRLFLILLDKHLRSLN 175 A ++F+PG YA +RL + ++ +EQG+ + L+ + +L Sbjct: 347 KAVARNVAFVPGAPFYANAPRRNTMRLAFVTVSPERIEQGITVLGELIRAEIAALT 402 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.138 0.412 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 12,661,425 Number of extensions: 476705 Number of successful extensions: 787 Number of sequences better than 1.0e-05: 28 Number of HSP's gapped: 768 Number of HSP's successfully gapped: 28 Length of query: 176 Length of database: 38,378,431 Length adjustment: 99 Effective length of query: 77 Effective length of database: 26,960,365 Effective search space: 2075948105 Effective search space used: 2075948105 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 112 (47.8 bits)