BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0112.0027.p (285 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA0268 [KE] COG1167 Transcriptional regulators containing a DNA-... 124 2e-28 CAC3651 [KE] COG1167 Transcriptional regulators containing a DNA... 106 4e-23 RSc0989 [KE] COG1167 Transcriptional regulators containing a DNA... 103 3e-22 mlr6174 [KE] COG1167 Transcriptional regulators containing a DNA... 103 3e-22 RSc0229 [KE] COG1167 Transcriptional regulators containing a DNA... 101 1e-21 >PA0268 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Length = 473 Score = 124 bits (311), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 97/280 (34%), Positives = 131/280 (46%), Gaps = 17/280 (6%) Query: 1 MHIDLLRSGSKPLPQQISDTLAQRITSGLLQPGFRLPSVRGLAATLKVSQVTVSKAYADL 60 M + L+ G L Q+ L I G L G RLP+ R LA L+VS+ TVS+AY L Sbjct: 1 MELQLILDGRHDLVGQLYRQLRDAILHGRLATGDRLPATRYLAERLEVSRKTVSEAYERL 60 Query: 61 EKKGHLICSQGKGCFVAEHERSGPGNGADWRDGYEDYLPRAQLWRNFGYS-------EVK 113 +G L G G FVA GP A + P A+ R S ++ Sbjct: 61 ASEGFLEGRVGSGTFVAR----GPAGEAPPQRADGPLRPAARWARIEPQSGLMDQRAPLR 116 Query: 114 YPFHLAAIHEDLLPLGPISTTMAALVTGQPELMASYGNFQGDPELREIMRRHLQ-PRGIH 172 Y F + P T + + Q A Y +GDPELR + R+L R + Sbjct: 117 YSFAGGTTDKRRFPFDTWRTCVLQALRLQQRSPAFYKETEGDPELRLAISRYLAINRAVQ 176 Query: 173 LATSDLMITSGTQQGIDLVARTFVGPGDTVYLEAPSYTGAIDVFAGRGAEMIFVPMDHEG 232 + LM+T G QQG+DL+AR + PGD +E P Y A GAE+ VP+D EG Sbjct: 177 CDWNALMVTQGAQQGLDLLARVMLDPGDLAVVEEPGYPPARASLLATGAEVRGVPVDAEG 236 Query: 233 MRVDVLTRLCDARPPKLIYTNPTFQNPSGVTMSMARRQRL 272 +RVD+L KL+Y P+ Q P G+ MS+ RR +L Sbjct: 237 LRVDLLPDNA-----KLVYVTPSHQFPLGMPMSLERRLQL 271 >CAC3651 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Length = 481 Score = 106 bits (265), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 59/261 (22%), Positives = 129/261 (49%), Gaps = 5/261 (1%) Query: 16 QISDTLAQRITSGLLQPGFRLPSVRGLAATLKVSQVTVSKAYADLEKKGHLICSQGKGCF 75 QI + + I +G+LQ +LPS R ++ L VS+ T+ Y L +G+ +GKG F Sbjct: 16 QIENYIKNLIETGILQKNEKLPSTREMSLLLDVSRNTIIDVYETLTNEGYTDTIKGKGTF 75 Query: 76 VAEHER-SGPGNGADWRDGYEDYLPRAQLWRNFGY----SEVKYPFHLAAIHEDLLPLGP 130 +++ + S + W + + A + ++ PF + +++L + Sbjct: 76 ISDKKIISKESHHLPWIEFINTHALDAASLDTTKHELRGTDDIIPFDSISPNKNLFDIDE 135 Query: 131 ISTTMAALVTGQPELMASYGNFQGDPELREIMRRHLQPRGIHLATSDLMITSGTQQGIDL 190 I +++ + + +YG +G L + ++ +++ +G+++ D++IT+G +G ++ Sbjct: 136 IKRDFLNIISIEGNNILNYGYAKGYKPLIDYLKIYMKHKGVNIDNKDILITNGFTEGFNI 195 Query: 191 VARTFVGPGDTVYLEAPSYTGAIDVFAGRGAEMIFVPMDHEGMRVDVLTRLCDARPPKLI 250 V T GDT++ E P++ ++ + + + MD +G+ +D L + PK + Sbjct: 196 VLSTITEKGDTIFCENPTHNTSLKIMKLHNLNIKGIDMDDDGINIDSLKDELEKELPKAV 255 Query: 251 YTNPTFQNPSGVTMSMARRQR 271 + PT+ NP+ + MS +R + Sbjct: 256 FLIPTYHNPTSIVMSPEKRLK 276 >RSc0989 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Length = 490 Score = 103 bits (258), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 79/266 (29%), Positives = 125/266 (46%), Gaps = 2/266 (0%) Query: 4 DLLRSGSKPLPQQISDTLAQRITSGLLQPGFRLPSVRGLAATLKVSQVTVSKAYADLEKK 63 D + S L Q+++ RI + + G R+PS+R LA +S+ TV +AY L + Sbjct: 26 DPIPSAQMTLVDQLTEWARMRIDERVFRAGMRMPSIRQLAQEKSISRFTVVEAYERLVAQ 85 Query: 64 GHLICSQGKGCFVAEHERSGPGNGADWRDGYEDYLPRAQLWRN-FGYSEVKYPFHLAAIH 122 G+L +G G +V E + P + A L RN F +E + + + Sbjct: 86 GYLESRRGSGFYVKERQAPLPEEPPAPPASARK-IDVAWLLRNMFHSAEPRKAPGIGFLP 144 Query: 123 EDLLPLGPISTTMAALVTGQPELMASYGNFQGDPELREIMRRHLQPRGIHLATSDLMITS 182 L I+ + AL ++G QG LR+ ++ L I +++TS Sbjct: 145 NGWLDGELIANALRALGRQNGNQFLAWGTPQGFLPLRQQLQTRLAELEIGARPDQIVMTS 204 Query: 183 GTQQGIDLVARTFVGPGDTVYLEAPSYTGAIDVFAGRGAEMIFVPMDHEGMRVDVLTRLC 242 G Q +DL+AR +V PGDTV + P++ FA +GA++I VP EG + L L Sbjct: 205 GITQSLDLIARQYVQPGDTVLVGDPAWFLMFGRFAAQGAQVIGVPYTTEGPDLVALEGLV 264 Query: 243 DARPPKLIYTNPTFQNPSGVTMSMAR 268 R PKL+ N NP+G ++S A+ Sbjct: 265 QVRRPKLLVINSVLHNPTGTSLSAAK 290 >mlr6174 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Length = 301 Score = 103 bits (257), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 21/270 (7%), Positives = 52/270 (19%), Gaps = 21/270 (7%) Query: 15 QQISDTLAQRITSGLLQPGFRLPSVRGLAATLKVSQVTVSKAYADLEKKGHLICSQGKGC 74 S L + + + + + R + + + + Sbjct: 19 VGKSTLLNKLLGQKISITSRKAQTTRHRIVGIHTEGAYQAIYVDTPGLHMEEKRAINRLM 78 Query: 75 FVAE----HE-------RSGPGNGADWRDGYEDYLPRAQLWRNFGYSEVKYPFHLAAIHE 123 A + G D E L + + + V ++ + Sbjct: 79 NKAASSSIGDVELVIFVVEGTRWTPD----DEMVLNKLREGKAPVILAVNKVDNVQEKAD 134 Query: 124 DLLPLGPISTTMAALVTGQPELMASYGNFQGDPELREIMRRHL-QPRGIHLATSDLMITS 182 L L +++ M L N + T Sbjct: 135 LLPHLQFLASQMNFLDIVPISAET-GLNVDTIAAIVRKHLPEATHHFPEDYITDRSQRFM 193 Query: 183 GTQQGIDLVARTFVGPGDTVYLEAPSYTGAIDVFAGRGAEMIFVPMDHEGMRVDVLTRLC 242 ++ + + R + + +I V + + V Sbjct: 194 ASEIIREKLMRFLGAELPYSVTVEIERFVSNERGGYDINGLILVEREGQKKMVIGNKGAK 253 Query: 243 DARPPKLIYTNPTFQNPSGVTMSMARRQRL 272 K I + + Sbjct: 254 ----IKTIGIEARKDMQEMFEAPVHLELWV 279 >RSc0229 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Length = 402 Score = 101 bits (252), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 48/113 (42%), Positives = 70/113 (61%) Query: 149 YGNFQGDPELREIMRRHLQPRGIHLATSDLMITSGTQQGIDLVARTFVGPGDTVYLEAPS 208 YG +G LRE + +Q RG +A +D+++T+G+QQG+DL+ + +G GDTV EAP+ Sbjct: 68 YGATEGFEPLREAIVTLMQARGATVANTDILVTTGSQQGLDLLGKVLIGEGDTVLTEAPT 127 Query: 209 YTGAIDVFAGRGAEMIFVPMDHEGMRVDVLTRLCDARPPKLIYTNPTFQNPSG 261 + AI F GA++ VP D +G+ +D L R A PK +Y P F NPSG Sbjct: 128 FLAAIQAFKLYGAKVAGVPTDEDGLDLDALERALAAGRPKFLYVIPNFGNPSG 180 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.320 0.138 0.418 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 22,160,143 Number of extensions: 936265 Number of successful extensions: 2065 Number of sequences better than 1.0e-05: 109 Number of HSP's gapped: 2013 Number of HSP's successfully gapped: 119 Length of query: 285 Length of database: 38,378,431 Length adjustment: 105 Effective length of query: 180 Effective length of database: 26,268,361 Effective search space: 4728304980 Effective search space used: 4728304980 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 115 (48.9 bits)