BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0106.0011.p
         (177 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

SMb21003 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene te...   138   4e-33
AGc4197 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tet...   128   5e-30
Cgl2071 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tet...    83   2e-16
SA0327 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetr...    79   5e-15

>SMb21003 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene
           tetrahydromethanopterin reductase and related
           flavin-dependent oxidoreductases
          Length = 346

 Score =  138 bits (348), Expect = 4e-33,   Method: Compositional matrix adjust.
 Identities = 11/165 (6%), Positives = 29/165 (17%), Gaps = 1/165 (0%)

Query: 6   AGSPESAVRAGTLGLPFALAMIGPVQPLDFASQAKLYKEAAARAGHDSSRLPVAAHAHGF 65
           +      V                    +  S      E           + + A++   
Sbjct: 179 SNETAFGVMRYLHLADKHDLPRIV-TIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLG 237

Query: 66  IAADTRKAMEQFFPSTYARTNVRAAEKGLPPYHRTDYDAACSLDGALYVGDPERVADKII 125
               T K +    P+    T      +      +    A   +     +   +     + 
Sbjct: 238 FGTLTGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMALAFVR 297

Query: 126 RLRKHVGVTRFLLHVPHGTMPHAEVMEAIRLLGTEVAPRVREEVA 170
           R             +         +   +          V +   
Sbjct: 298 RQPFVASTLLGATTMDQLKTNIESLHLELSEDVLAEIEAVHQVYT 342


>AGc4197 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene
           tetrahydromethanopterin reductase and related
           flavin-dependent oxidoreductases
          Length = 346

 Score =  128 bits (321), Expect = 5e-30,   Method: Compositional matrix adjust.
 Identities = 13/164 (7%), Positives = 31/164 (18%), Gaps = 1/164 (0%)

Query: 6   AGSPESAVRAGTLGLPFALAMIGPVQPLDFASQAKLYKEAAARAGHDSSRLPVAAHAHGF 65
             +    +R   L     L  I       ++   + ++   A          +A    GF
Sbjct: 180 NETAFGVMRYLHLADKHDLPRIVT-IQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGF 238

Query: 66  IAADTRKAMEQFFPSTYARTNVRAAEKGLPPYHRTDYDAACSLDGALYVGDPERVADKII 125
                +                R          +                    +A    
Sbjct: 239 GTLTGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMALAFVRR 298

Query: 126 RLRKHVGVTRFLLHVPHGTMPHAEVMEAIRLLGTEVAPRVREEV 169
           +      +          T   +  +E    +  E+    +   
Sbjct: 299 QPFVASTLLGATTMDQLKTNIESLHLELSEDVLAEIEAVHQVYT 342


>Cgl2071 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene
           tetrahydromethanopterin reductase and related
           flavin-dependent oxidoreductases
          Length = 346

 Score = 83.2 bits (204), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 11/162 (6%), Positives = 28/162 (17%), Gaps = 4/162 (2%)

Query: 6   AGSPESAVRAGTLGLPFALAMIGPVQPLDFASQAKLYKEAAARAGHDSSRLPVAAHAHGF 65
                  +                   L+ + +  L + +        +           
Sbjct: 185 GVMRYLHLADKHDLPRIVTIQNPYS-LLNRSFEVGLAEVSQYEGVELLA--YSCLGFGTL 241

Query: 66  IAADTRKAMEQFFPSTYARTNVRAAEKGLPPYHRTDYDAACSLDGALYVGDPERVADKII 125
                  A      +T      R + +          D A    G            +  
Sbjct: 242 TGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARR-HGLDPAQMALAFVRRQP 300

Query: 126 RLRKHVGVTRFLLHVPHGTMPHAEVMEAIRLLGTEVAPRVRE 167
            +   +     +  +          +    L   E   +V  
Sbjct: 301 FVASTLLGATTMDQLKTNIESLHLELSEDVLAEIEAVHQVYT 342


>SA0327 [C] COG2141 Coenzyme F420-dependent N5,N10-methylene
           tetrahydromethanopterin reductase and related
           flavin-dependent oxidoreductases
          Length = 346

 Score = 78.6 bits (192), Expect = 5e-15,   Method: Compositional matrix adjust.
 Identities = 0/168 (0%), Positives = 0/168 (0%), Gaps = 9/168 (5%)

Query: 6   AGSPESAVRAGTLGLPFALAMIGPVQPLDFASQAKLYKEAAARAGHDSSR--LPVAAHAH 63
             + +  +            +      +  A  ++                      +  
Sbjct: 191 HLADKHDLPRIVTIQNPYSLLNRS-FEVGLAEVSQYEGVELLAYSCLGFGTLTGKYLNGA 249

Query: 64  GFIAADTRKAMEQFFPS-TYARTNVRAAEKGLPPYHRTDYDAACSLDGALYVGDPERVAD 122
               A           S    +  V A            +    +     +V     VA 
Sbjct: 250 KPAGARNTLFSRFTRYSGEQTQKAVAAY-----VDIARRHGLDPAQMALAFVRRQPFVAS 304

Query: 123 KIIRLRKHVGVTRFLLHVPHGTMPHAEVMEAIRLLGTEVAPRVREEVA 170
                                                           
Sbjct: 305                                                  352


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.320    0.134    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 12,905,015
Number of extensions: 566951
Number of successful extensions: 922
Number of sequences better than 1.0e-05: 4
Number of HSP's gapped: 916
Number of HSP's successfully gapped: 4
Length of query: 177
Length of database: 38,378,431
Length adjustment: 99
Effective length of query: 78
Effective length of database: 26,960,365
Effective search space: 2102908470
Effective search space used: 2102908470
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 112 (47.8 bits)