BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0106.0004.p (219 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value MA4278 [S] COG1262 Uncharacterized conserved protein 114 1e-25 MA0649 [S] COG1262 Uncharacterized conserved protein 112 3e-25 all3226_2 [S] COG1262 Uncharacterized conserved protein 108 7e-24 MA1951 [S] COG1262 Uncharacterized conserved protein 94 1e-19 MA3092 [S] COG1262 Uncharacterized conserved protein 90 2e-18 >MA4278 [S] COG1262 Uncharacterized conserved protein Length = 270 Score = 114 bits (284), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 72/173 (41%), Positives = 86/173 (49%), Gaps = 37/173 (21%) Query: 61 NVSWNDAILFCNKLSQESGLQECYSISEDGESVSCNWEADGYRLPTEAEWQYACKAGTTG 120 NVSW D F NKL++ G D YRLP+EAEW+YAC+AGTT Sbjct: 116 NVSWYDVQEFINKLNEMEG-------------------TDKYRLPSEAEWEYACRAGTTT 156 Query: 121 -YQYGE----LDAVAWYEGNSGGVVHEAGQKLPNAWGLYDMLGNVWEWCWDIYDENVYG- 174 Y +G+ L AWY NS H GQK PN+WGLY M GNV EWC D + +N G Sbjct: 157 RYFFGDDESKLGDYAWYWNNSDRKTHPVGQKKPNSWGLYGMSGNVLEWCQDKWHDNYDGA 216 Query: 175 ------------SYRIFRGGSWAEEARGCGATCRRRSHPTFHIDDLGFRLARS 215 SYR+ R GSW C + R R P H+ +GFRL RS Sbjct: 217 PSDGSAWEEGNSSYRVIRNGSWNASPMVCRSAYRFRFVPDTHVHFIGFRLLRS 269 >MA0649 [S] COG1262 Uncharacterized conserved protein Length = 307 Score = 112 bits (281), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 70/171 (40%), Positives = 83/171 (48%), Gaps = 37/171 (21%) Query: 62 VSWNDAILFCNKLSQESGLQECYSISEDGESVSCNWEADGYRLPTEAEWQYACKAGT-TG 120 VSWND F KL+ D YR P+EAEW+YAC+AG T Sbjct: 154 VSWNDVQEFVEKLNAAEN-------------------TDKYRSPSEAEWEYACRAGIQTR 194 Query: 121 YQYGE----LDAVAWYEGNSGGVVHEAGQKLPNAWGLYDMLGNVWEWCWDIYDENVY--- 173 Y +G+ L+ AWY NSG H G+K PN+WGLYDM GNVWEW D + EN Sbjct: 195 YSFGDDESKLNEYAWYVKNSGRKTHPIGRKQPNSWGLYDMHGNVWEWVQDKWHENYKDSP 254 Query: 174 ----------GSYRIFRGGSWAEEARGCGATCRRRSHPTFHIDDLGFRLAR 214 GS R+ RGGSW A C + R P H +LGFRL R Sbjct: 255 SDGSAWEDGGGSLRVSRGGSWYCNAESCRSAGRFGREPDSHFANLGFRLLR 305 >all3226_2 [S] COG1262 Uncharacterized conserved protein Length = 246 Score = 108 bits (270), Expect = 7e-24, Method: Compositional matrix adjust. Identities = 79/258 (30%), Positives = 104/258 (40%), Gaps = 67/258 (25%) Query: 3 QMILIPAGEVQL--------RDDRVKTKWTARVDSFWLAPVPVTNALYDR---------- 44 +M+ IP G + R DR + V F++ VT A Y Sbjct: 4 EMVQIPGGTFTMGSPESEAERFDRESPQRQVTVPGFFMGKYAVTQAQYQAVMGGNILQKI 63 Query: 45 --XXXXXXXXXXXXXXXXNVSWNDAILFCNKLSQESGLQECYSISEDGESVSCNWEADGY 102 VSWNDA+ FC KLSQ++G Y Sbjct: 64 IGNKNNPSYFKGEKRPVEQVSWNDAVEFCQKLSQKTGRT--------------------Y 103 Query: 103 RLPTEAEWQYACKAGTTGYQY-------------GELDAVAWYEGNSGGVVHEAGQKLPN 149 RLP+EAEW+YAC+AGTT Y GE A +G G G PN Sbjct: 104 RLPSEAEWEYACRAGTTTPFYFGETITTDLVNYNGEFPYGAAPKGKYRGETTNVGIFPPN 163 Query: 150 AWGLYDMLGNVWEWCWDIYDENVYGS--------------YRIFRGGSWAEEARGCGATC 195 ++GLYDM GNVWEWC DIY++N G+ ++ RGGSW AR C Sbjct: 164 SFGLYDMCGNVWEWCEDIYNDNYQGAPTDGSALLTSKNNNIKLVRGGSWHSHARSCRCAY 223 Query: 196 RRRSHPTFHIDDLGFRLA 213 R + + ++GFR+ Sbjct: 224 RDMHARAYRLFNVGFRVV 241 >MA1951 [S] COG1262 Uncharacterized conserved protein Length = 311 Score = 94.4 bits (233), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 77/245 (31%), Positives = 107/245 (43%), Gaps = 49/245 (20%) Query: 3 QMILIPAGEVQL----RDDRVKTKWTARV------DSFWLAPVPVTNALYDRXXXXXXXX 52 + +LIPAGE ++ R+ R K W + V F+L PVT + + Sbjct: 81 EFVLIPAGEFEMGSPSREKRRKL-WESPVHRVSIKKPFYLGRYPVTQEQWSKVTGSNPSF 139 Query: 53 XX-XXXXXXNVSWNDAILFCNKLSQESGLQECYSISEDGESVSCNWEADGYRLPTEAEWQ 111 VSW +A F KL+ ++ +G + YRLPTEAEW+ Sbjct: 140 FRGEKHPVETVSWEEAQAFIRKLN---------TLENNGGRSAI------YRLPTEAEWE 184 Query: 112 YACKAGTTG-YQYG----ELDAVAWYEGNSGGVVHEAGQKLPNAWGLYDMLGNVWEWCWD 166 YA +AG+TG Y +G +L AW+ NSG H G K PN WGLYD+ GNV EW D Sbjct: 185 YAARAGSTGSYFFGNDETKLKEHAWFLENSGLETHPVGLKKPNPWGLYDIYGNVGEWVQD 244 Query: 167 IYD-----------------ENVYGSYRIFRGGSWAEEARGCGATCRRRSHPTFHIDDLG 209 Y + + RI RGG W A C + R + ++ LG Sbjct: 245 EYHISYKGAPSDGRAWESSFQGISTQVRIRRGGGWNGNAGCCRSAERLFAPQDKRLNSLG 304 Query: 210 FRLAR 214 FR+ + Sbjct: 305 FRVVK 309 >MA3092 [S] COG1262 Uncharacterized conserved protein Length = 291 Score = 90.1 bits (222), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 52/135 (38%), Positives = 72/135 (53%), Gaps = 18/135 (13%) Query: 99 ADGYRLPTEAEWQYACKAGTTG-YQYGE----LDAVAWYEGNSGGVVHEAGQKLPNAWGL 153 ++ YRLPTEAEW+YAC+AGTT + +G+ L W ++ G H GQKLPN WGL Sbjct: 156 SNTYRLPTEAEWEYACRAGTTTRFSFGDENEDLIEYGWSGYDANGTSHPVGQKLPNPWGL 215 Query: 154 YDMLGNVWEWCWDIYDENVYGSYR-------------IFRGGSWAEEARGCGATCRRRSH 200 YDM GN+WE D + N G+ + RGGSW + C ++ R + Sbjct: 216 YDMHGNLWELTQDSWHSNYEGAPSDGSAWSDKNQTAFVGRGGSWLDGPNLCTSSFRGSNS 275 Query: 201 PTFHIDDLGFRLARS 215 + LGFRL ++ Sbjct: 276 VDAKVSCLGFRLVKN 290 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.136 0.464 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 17,124,130 Number of extensions: 690798 Number of successful extensions: 749 Number of sequences better than 1.0e-05: 18 Number of HSP's gapped: 717 Number of HSP's successfully gapped: 18 Length of query: 219 Length of database: 38,378,431 Length adjustment: 102 Effective length of query: 117 Effective length of database: 26,614,363 Effective search space: 3113880471 Effective search space used: 3113880471 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 114 (48.5 bits)