BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0101.0007.p (275 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PM1714 [K] COG1737 Transcriptional regulators 184 2e-46 YPO3017 [K] COG1737 Transcriptional regulators 178 7e-45 STM1127 [K] COG1737 Transcriptional regulators 169 5e-42 L192289 [K] COG1737 Transcriptional regulators 166 4e-41 BH2675 [K] COG1737 Transcriptional regulators 154 2e-37 >PM1714 [K] COG1737 Transcriptional regulators Length = 288 Score = 184 bits (466), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 103/280 (36%), Positives = 163/280 (58%), Gaps = 8/280 (2%) Query: 2 EMTDRINTYYPSMTKSEQKVAKCVLEHPDNLIYLSVTELADFAGTGETTVMRFCRKIGFK 61 ++ D I + S+TK+E+++A +L PD L S++++A GE T +RFCR +GF+ Sbjct: 6 KILDTIGALHDSLTKTEKRIAATILASPDLLSQSSLSDIAKHLDVGEATFIRFCRTLGFR 65 Query: 62 GYQDFKLMLAQGLPKQQAPSGR----DGGDADD----ATLLYESMVNILQSSLGMLDREQ 113 G+ DFKL LA L ++ D +DD A L ++ N++ ++ +LD + Sbjct: 66 GFTDFKLELAIELATREKQYHSLLDTDISPSDDPKNIAAKLQGAVTNVIAETINLLDFNE 125 Query: 114 LEEAINQIDAAHHMQFFGVGSSAITALDAKNRLLRIGRRVEAIADSHIQSMMAVTMGEGD 173 LE+ +N + A + FGVGSS ITA DAKN+ +RIG +V++ +++H M A M EGD Sbjct: 126 LEKVVNTMMKAKRIFLFGVGSSGITAEDAKNKFMRIGLQVDSTSNNHFMYMQAALMQEGD 185 Query: 174 VAFGISVSGSTLDTNDMLMKAKQNGAKVIAMTNYAKSPIASIADIVLLTAGKESPLEGGS 233 V GIS SG + + L AK+N A IA+T+ +SPI AD VL+ ++ L+G S Sbjct: 186 VVVGISHSGYSKEVIQALNIAKKNSATTIAITHNLRSPITHAADYVLINGNRQGQLQGDS 245 Query: 234 MGAKISQLFIIDLICKGLERRHADETKNMKELTARAVIDR 273 MG KI+QLF++DLI + + D K+ T ++++ Sbjct: 246 MGTKIAQLFVLDLIYTLIVQATEDTATKTKQKTVNVILEQ 285 >YPO3017 [K] COG1737 Transcriptional regulators Length = 292 Score = 178 bits (452), Expect = 7e-45, Method: Compositional matrix adjust. Identities = 101/277 (36%), Positives = 160/277 (57%), Gaps = 8/277 (2%) Query: 2 EMTDRINTYYPSMTKSEQKVAKCVLEHPDNLIYLSVTELADFAGTGETTVMRFCRKIGFK 61 ++ D + S+T+S Q++A +L P + LS+ +L+ GE T++RFCR +G+K Sbjct: 12 KILDALGAMQNSLTRSAQRIAAYILAQPAQVTQLSIADLSALTQAGEATIIRFCRTLGYK 71 Query: 62 GYQDFKLMLAQGLPKQQAPSGR----DGGDADD----ATLLYESMVNILQSSLGMLDREQ 113 G+QDFK+ LA + + D + DD + L ++ N+L +L +L E Sbjct: 72 GFQDFKMDLAIEVATRHNSENSLLDADVQEGDDTLAIGSKLQSAINNVLSETLNLLSIES 131 Query: 114 LEEAINQIDAAHHMQFFGVGSSAITALDAKNRLLRIGRRVEAIADSHIQSMMAVTMGEGD 173 +E+ + + A + FGVGSS ITA DAK +L+RIG RV+A ++H M A M GD Sbjct: 132 VEQVVKVLRPADRICIFGVGSSGITAEDAKGKLMRIGLRVDAATNNHFMYMQASLMNPGD 191 Query: 174 VAFGISVSGSTLDTNDMLMKAKQNGAKVIAMTNYAKSPIASIADIVLLTAGKESPLEGGS 233 VA GIS SG++ +T L AK+ GA +A+T+ S I +AD VL+ ++ L+G S Sbjct: 192 VAIGISHSGTSAETVQALKLAKEAGATTVALTHNMGSRITELADYVLINGNRQGQLQGDS 251 Query: 234 MGAKISQLFIIDLICKGLERRHADETKNMKELTARAV 270 +G KI+QLF++DLI L + + +++K T +AV Sbjct: 252 IGTKIAQLFVLDLIYALLVKADPAQAESIKRKTTQAV 288 >STM1127 [K] COG1737 Transcriptional regulators Length = 293 Score = 169 bits (428), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 96/278 (34%), Positives = 159/278 (57%), Gaps = 9/278 (3%) Query: 2 EMTDRINTYYPSMTKSEQKVAKCVLEHPDNLIYLSVTELADFAGTGETTVMRFCRKIGFK 61 ++ D + S+T++ Q++A+ +L P + S+ +L+ GE TV+RFCR +G+K Sbjct: 12 KILDTLGAMQKSLTRASQRIAQYILAFPRQVTQSSIADLSRETQAGEATVIRFCRTLGYK 71 Query: 62 GYQDFKLMLAQGLPKQQAPSGRDGGDA-----DDATL----LYESMVNILQSSLGMLDRE 112 G+QDFK+ LA L ++ DA DDA L ++ N+L +L +LD + Sbjct: 72 GFQDFKMDLAIELATTESDDSSPLLDAEVSESDDAHAIGLKLQNTISNVLSETLNLLDMQ 131 Query: 113 QLEEAINQIDAAHHMQFFGVGSSAITALDAKNRLLRIGRRVEAIADSHIQSMMAVTMGEG 172 Q+ ++ + H + FGVGSS ITALD K++L+RIG R +A++++H M A + G Sbjct: 132 QVLGVVDALRHCHSVYIFGVGSSGITALDMKHKLMRIGLRGDAVSNNHFMYMQATLLKAG 191 Query: 173 DVAFGISVSGSTLDTNDMLMKAKQNGAKVIAMTNYAKSPIASIADIVLLTAGKESPLEGG 232 DVA G+S SG++ +T L A+Q GA +A+T+ SP+ AD L+ ++ L+G Sbjct: 192 DVAMGVSHSGTSPETVHSLRLARQAGATTVAITHNLGSPLCEEADFCLINGNRQGMLQGD 251 Query: 233 SMGAKISQLFIIDLICKGLERRHADETKNMKELTARAV 270 S+G K +QLF+ DL+ L + ++ + K T A+ Sbjct: 252 SIGTKAAQLFVFDLLYTLLVQSSPEQARESKLRTMNAL 289 >L192289 [K] COG1737 Transcriptional regulators Length = 273 Score = 166 bits (420), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 99/277 (35%), Positives = 161/277 (58%), Gaps = 11/277 (3%) Query: 1 MEMTDRINTYYPSMTKSEQKVAKCVLEHPDNLIYLSVTELADFAGTGETTVMRFCRKIGF 60 M++ I Y ++TKSE+K+A VLE P+++IY ++ ++ G+ T++RFC+K+GF Sbjct: 1 MKIEQVIEEKYKTLTKSEKKIANYVLESPNHIIYGTMNDIKSEIHVGDATIIRFCQKLGF 60 Query: 61 KGYQDFKLMLAQGLPKQQAPSGRDGGDADDATLLYES----MVNILQSSLGMLDREQLEE 116 G+ D K+ +A+ Q+ A D+ L ++ +VN L+++ L E LE Sbjct: 61 SGFSDLKIEIAKEDYSQKES------QAKDSELFFDEKERKIVNSLETTKRKLSIELLER 114 Query: 117 AINQIDAAHHMQFFGVGSSAITALDAKNRLLRIGRRVEAIADSHIQSMMAVTMGEGDVAF 176 + + A + FGVG S TA D + LRIG + +AI+D+H Q+ A + D+ Sbjct: 115 SSALLSNASAIYIFGVGLSGNTAKDLEAMFLRIGIQAKAISDTHFQAQTAAILKNTDLVI 174 Query: 177 GISVSGSTLDTNDMLMKAKQNGAKVIAMTNYAKSPIASIADIVLLTAGKESPLEGGSMGA 236 GIS+SG TLD + L AK + AK++++T+ SPIA ++DIVL T +E +GGS+ Sbjct: 175 GISLSGRTLDLYESLKIAKGHTAKILSITSNLVSPIAQLSDIVLQTTAEE-FFDGGSLSG 233 Query: 237 KISQLFIIDLICKGLERRHADETKNMKELTARAVIDR 273 KISQL+I +L+ + E+ +E +E RAVI + Sbjct: 234 KISQLYICELLVRHHEKIFENEALKSREEIIRAVISK 270 >BH2675 [K] COG1737 Transcriptional regulators Length = 287 Score = 154 bits (388), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 86/260 (33%), Positives = 144/260 (55%), Gaps = 4/260 (1%) Query: 6 RINTYYPSMTKSEQKVAKCVLEHPDNLIYLSVTELADFAGTGETTVMRFCRKIGFKGYQD 65 RI Y S ++ E++VA +L +P+ +I+ ++ ++A+ G E TV RFC+++GF+GYQ Sbjct: 14 RIRASYSSFSEKEKQVADYILANPNKMIHSTINQVAEDLGVAEATVFRFCKRLGFQGYQA 73 Query: 66 FKLMLAQGL--PKQ--QAPSGRDGGDADDATLLYESMVNILQSSLGMLDREQLEEAINQI 121 K+ LA + P Q D + A +++S + L+ ++ +LD E + A++ + Sbjct: 74 MKIALASEIVTPIQDIHETIQEDDDEKTVADKVFKSNIRTLEDTMQVLDVESFKRAVDYL 133 Query: 122 DAAHHMQFFGVGSSAITALDAKNRLLRIGRRVEAIADSHIQSMMAVTMGEGDVAFGISVS 181 A ++F+G G S + ALDA ++ LR G A DSH Q M A + + DVA IS S Sbjct: 134 LHARRIEFYGNGGSGVIALDAHHKFLRTGIPSAAYHDSHFQVMSASQLTKQDVAVFISHS 193 Query: 182 GSTLDTNDMLMKAKQNGAKVIAMTNYAKSPIASIADIVLLTAGKESPLEGGSMGAKISQL 241 G+ D L AK + K I +T Y K+P++ DI L T +E+ ++ ++++QL Sbjct: 194 GTNRDLLQALEVAKSHQVKTIGITTYGKTPLSKEVDIALYTVSQETEYRSEALASRLAQL 253 Query: 242 FIIDLICKGLERRHADETKN 261 IID + + R DE K+ Sbjct: 254 SIIDALYVNVSIRRKDEMKS 273 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.133 0.366 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 18,552,955 Number of extensions: 744906 Number of successful extensions: 8637 Number of sequences better than 1.0e-05: 82 Number of HSP's gapped: 8558 Number of HSP's successfully gapped: 82 Length of query: 275 Length of database: 38,378,431 Length adjustment: 105 Effective length of query: 170 Effective length of database: 26,268,361 Effective search space: 4465621370 Effective search space used: 4465621370 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 115 (48.9 bits)