BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0100.0004.p (146 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH0951 [P] COG0735 Fe2+/Zn2+ uptake regulation proteins 202 1e-52 BS_perR [P] COG0735 Fe2+/Zn2+ uptake regulation proteins 196 1e-50 lin1791 [P] COG0735 Fe2+/Zn2+ uptake regulation proteins 182 2e-46 SA1678 [P] COG0735 Fe2+/Zn2+ uptake regulation proteins 177 4e-45 aq_1207 [P] COG0735 Fe2+/Zn2+ uptake regulation proteins 114 6e-26 >BH0951 [P] COG0735 Fe2+/Zn2+ uptake regulation proteins Length = 145 Score = 202 bits (514), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 94/139 (67%), Positives = 113/139 (81%) Query: 8 VQHALEQLKTTGVRITPQRHAILSYLMEAMNHPTADDIYRALEPQFPSMSVATVYNNLKM 67 +Q A+E LKTT VR+TPQRHAIL YL E+M HPTAD+IY+ALE +FP+MSVATVYNNL++ Sbjct: 6 LQGAIEALKTTRVRMTPQRHAILEYLFESMTHPTADEIYKALEGRFPNMSVATVYNNLRV 65 Query: 68 FMEAGMVRELTYGDNSSRFDANVSDHYHVICQECGRIEDFSYSSLHEVEQRAEQATGFKI 127 F EAG+V+ELTYGD+SSRFD SDHYHVIC+ECG+I DF Y L EVE AE TGFK+ Sbjct: 66 FKEAGIVKELTYGDSSSRFDCVTSDHYHVICEECGKIVDFHYPGLDEVETLAEHVTGFKV 125 Query: 128 HGLRMELYGICKCCTEKTQ 146 RME+YGIC C +K+Q Sbjct: 126 SSHRMEIYGICPDCQKKSQ 144 >BS_perR [P] COG0735 Fe2+/Zn2+ uptake regulation proteins Length = 297 Score = 196 bits (497), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 10/137 (7%), Positives = 24/137 (17%) Query: 8 VQHALEQLKTTGVRITPQRHAILSYLMEAMNHPTADDIYRALEPQFPSMSVATVYNNLKM 67 T S L + + + +T L Sbjct: 6 KAPLNLLRAFEAAGRTGAFALAASELELSPSAISHAIRKLENLLDVRLFQRSTREITLTK 65 Query: 68 FMEAGMVRELTYGDNSSRFDANVSDHYHVICQECGRIEDFSYSSLHEVEQRAEQATGFKI 127 E + + + A V+ + L + + + + Sbjct: 66 EGEILLEHIQRGFNELQQGLALVTADESRPLRLHTAPSFAHQWLLPRLGKFIRENPSIDL 125 Query: 128 HGLRMELYGICKCCTEK 144 Y + Sbjct: 126 RLSASTEYARFEQDDFD 142 >lin1791 [P] COG0735 Fe2+/Zn2+ uptake regulation proteins Length = 148 Score = 182 bits (462), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 82/144 (56%), Positives = 108/144 (75%) Query: 1 VALMGSGVQHALEQLKTTGVRITPQRHAILSYLMEAMNHPTADDIYRALEPQFPSMSVAT 60 +A+ + ++ A++ LK TGVRITPQRHAIL +L+ + HPTADDIYR+LE FP+MSVAT Sbjct: 1 MAVSNATLKEAVDVLKKTGVRITPQRHAILEFLINSHTHPTADDIYRSLEGNFPNMSVAT 60 Query: 61 VYNNLKMFMEAGMVRELTYGDNSSRFDANVSDHYHVICQECGRIEDFSYSSLHEVEQRAE 120 VYNNL++F +AG+++EL+YGD SSRFD + S+HYH IC CG+I DF Y L EVE A Sbjct: 61 VYNNLRVFRDAGLIKELSYGDASSRFDFSTSNHYHAICNVCGKIVDFHYPGLDEVEHFAA 120 Query: 121 QATGFKIHGLRMELYGICKCCTEK 144 TG++I R+E+YG C C EK Sbjct: 121 HVTGYEIDNHRLEVYGTCPECKEK 144 >SA1678 [P] COG0735 Fe2+/Zn2+ uptake regulation proteins Length = 148 Score = 177 bits (450), Expect = 4e-45, Method: Compositional matrix adjust. Identities = 77/142 (54%), Positives = 108/142 (76%), Gaps = 4/142 (2%) Query: 7 GVQHALEQ----LKTTGVRITPQRHAILSYLMEAMNHPTADDIYRALEPQFPSMSVATVY 62 ++H LE+ L+ G+RITPQR AIL YL+ + HPTAD+IY+AL P FP++SVAT+Y Sbjct: 7 SIEHELEESIASLRQAGIRITPQRQAILRYLISSHTHPTADEIYQALSPDFPNISVATIY 66 Query: 63 NNLKMFMEAGMVRELTYGDNSSRFDANVSDHYHVICQECGRIEDFSYSSLHEVEQRAEQA 122 NNL++F + G+V+ELTYGD+SSRFD N +HYH+IC++CG+I DF Y L+E+E+ A+ Sbjct: 67 NNLRVFKDIGIVKELTYGDSSSRFDFNTHNHYHIICEQCGKIVDFQYPQLNEIERLAQHM 126 Query: 123 TGFKIHGLRMELYGICKCCTEK 144 T F + RME+YG+CK C +K Sbjct: 127 TDFDVTHHRMEIYGVCKECQDK 148 >aq_1207 [P] COG0735 Fe2+/Zn2+ uptake regulation proteins Length = 144 Score = 114 bits (284), Expect = 6e-26, Method: Compositional matrix adjust. Identities = 51/139 (36%), Positives = 89/139 (64%), Gaps = 3/139 (2%) Query: 8 VQHALEQLKTTGVRITPQRHAILSYLMEAMNHPTADDIYRALEPQFPSMSVATVYNNLKM 67 ++ +++ K TG++ITPQR A+ L+++ NHPT ++IY ++ +P +S+ATVY L+ Sbjct: 8 LEFFVKRCKETGLKITPQRMAVYEVLLKSDNHPTVEEIYEEVKKLYPYVSLATVYRTLET 67 Query: 68 FMEAGMVRELTYGDNSSRFDANVSDHYHVICQECGRIEDFSYSSLHEVEQRAEQATGFKI 127 G+V+++ + NS+R+DAN+ +H+H+IC++CG+IED L + E+ G+K Sbjct: 68 LENIGLVKKVCFWGNSARYDANLEEHHHLICEKCGKIEDI---KLDQKLNIPEEFYGYKT 124 Query: 128 HGLRMELYGICKCCTEKTQ 146 + +YGIC C K Q Sbjct: 125 ESYSVNVYGICPDCRAKMQ 143 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.133 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 9,855,905 Number of extensions: 352429 Number of successful extensions: 1351 Number of sequences better than 1.0e-05: 391 Number of HSP's gapped: 972 Number of HSP's successfully gapped: 391 Length of query: 146 Length of database: 38,378,431 Length adjustment: 96 Effective length of query: 50 Effective length of database: 27,306,367 Effective search space: 1365318350 Effective search space used: 1365318350 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 110 (47.0 bits)