BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0094.0003.p (295 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_ycnC [K] COG1309 Transcriptional regulator 143 3e-34 BS_yerO [K] COG1309 Transcriptional regulator 102 9e-22 CC0732 [K] COG1309 Transcriptional regulator 57 2e-08 aq_2179 [K] COG1309 Transcriptional regulator 57 3e-08 aq_281 [K] COG1309 Transcriptional regulator 55 1e-07 >BS_ycnC [K] COG1309 Transcriptional regulator Length = 292 Score = 143 bits (360), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 85/298 (28%), Positives = 154/298 (51%), Gaps = 11/298 (3%) Query: 1 MIVTREEVVQSATRLFKERGFLSTTIQDIADDCGIAKGSVYKYFPSKEDLFSEVFNQCHN 60 M+ + +++ +A +LF E+ F S ++Q IA++C ++K S+YK F SKEDL E+ + Sbjct: 1 MLDKKTDILLAARKLFSEKDFTSVSMQAIAEECKMSKASIYKLFQSKEDLLLELLSFNQK 60 Query: 61 NYFDQVDELTRLPGLSPEEQFVQQIVLRFRYFMEYKHILVEFTELPIQQDPKFQPLR--- 117 L L+PEE+ Q++ + F + +F + +P+ R Sbjct: 61 QMVAAASRLQENTALTPEERLTQKVKMELEGFRRNQ----QFFNMLTYGNPRLHNDRVKQ 116 Query: 118 --HKVRGRLIRWHRECLLHVYGEEIQPFLWDLVAIYRAILKEYLFWIVYEERSLSLEETA 175 H+ R +I WHR+ L+ YGE I PF+WDLV I +++E+L I EE+ L L+ A Sbjct: 117 HIHQTRSTIICWHRDSLIQAYGETILPFVWDLVIILHGMMREFLMLIKIEEKPLELDPIA 176 Query: 176 KFILDKLHVLVKHMMTSDLKSMLNQTSFERYLNWGLEDRQGEKGQILSELFREMDTAINT 235 +FI+ L+ ++K+ T +S+L + E Y++ + +K +LSE +E+ I++ Sbjct: 177 EFIISTLNQIIKNRETR--QSLLPPEAIELYIHSASSYKPKDKSVLLSESLKELHKGISS 234 Query: 236 IPAGAVHRSEIRELYRFIQTEVSKEAANHPLIQASLFYLEREKELKSLVVQLRNIIFS 293 + A E+ ++ E KE L+++ + YLE+ L V L+ ++ + Sbjct: 235 LSAADYDVDELTSAAAMLEEEAKKEEPRAFLLKSLIGYLEQTGVLTQPVSMLKTLLIT 292 >BS_yerO [K] COG1309 Transcriptional regulator Length = 289 Score = 102 bits (253), Expect = 9e-22, Method: Compositional matrix adjust. Identities = 84/296 (28%), Positives = 153/296 (51%), Gaps = 29/296 (9%) Query: 5 REEVVQSATRLFKERGFLSTTIQDIADDCGIAKGSVYKYFPSKEDLF---SEVFNQCHNN 61 +E +++++ RLF ++GF +TTIQ+IA +CGI+KG+ Y +F SKE L E + N Sbjct: 5 KERIIKTSIRLFAKKGFAATTIQEIASECGISKGAFYLHFKSKEALLLSACEYYIGMSMN 64 Query: 62 YFDQVDELTRLPGLSPEEQFVQQIVLRFRYFMEYKH-ILVEFTELPIQQDPKFQPLRHKV 120 ++E L G P+E +QI +F F ++K I++ TE I ++ + + +KV Sbjct: 65 KMKNIEE--DLAGKPPKEVLKKQIGAQFEDFRDHKDFIVLLLTENIIPENQEIKQYFYKV 122 Query: 121 RGRLIRWHRECLLHVYGEEIQPFLWDLVAIYRAILKEYLFWIVYE-ERSLSLEETAKFIL 179 + +R LL YGE I+ ++ DL + R I+ Y+ +V+ E ++ EE + FI+ Sbjct: 123 TMETDKLYRNALLVSYGEGIERYVADLSIMARGIVHSYMNVMVFNGELNIDAEEISAFII 182 Query: 180 DKLHVLVKHMMTSDLKSMLNQTSFERYLNWGLEDRQGEKGQILSELFREMDTAINTIPAG 239 ++L LV+ + S L ++++ F K Q+L ++ + + + T+P Sbjct: 183 ERLDDLVQGLSRSALNPIVSKDIFNPM--------PAGKDQLLEDIQKVKENS--TLP-- 230 Query: 240 AVHRSEIRELYRFIQTEVSKEAANHPLIQASLFYLE--REKELKSLVVQLRNIIFS 293 +I I+ E++++ P+I+ L L +KE V +LR +I S Sbjct: 231 ----EDITVSLDVIEEELTQDKPRKPIIKGMLSNLAGTNDKE----VERLRALILS 278 >CC0732 [K] COG1309 Transcriptional regulator Length = 215 Score = 57.4 bits (137), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 26/68 (38%), Positives = 40/68 (58%) Query: 4 TREEVVQSATRLFKERGFLSTTIQDIADDCGIAKGSVYKYFPSKEDLFSEVFNQCHNNYF 63 TRE V+ +A RLF ERG+ TI+DIA G++ G+V+ F K +LF E+ + + Sbjct: 28 TRERVLAAARRLFSERGYEGATIRDIAQAAGMSTGAVFASFADKSELFEEILTADYEVIY 87 Query: 64 DQVDELTR 71 Q+ + R Sbjct: 88 AQMIQAAR 95 >aq_2179 [K] COG1309 Transcriptional regulator Length = 666 Score = 57.0 bits (136), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 5/55 (9%), Positives = 9/55 (16%) Query: 4 TREEVVQSATRLFKERGFLSTTIQDIADDCGIAKGSVYKYFPSKEDLFSEVFNQC 58 + + E I P + S F + Sbjct: 14 GLYINEKGKVKGDFEHPANLGDICKKPLYLPKVLNRGRIAKPMYRENKSHSFREI 68 >aq_281 [K] COG1309 Transcriptional regulator Length = 179 Score = 55.5 bits (132), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 22/54 (40%), Positives = 37/54 (68%) Query: 4 TREEVVQSATRLFKERGFLSTTIQDIADDCGIAKGSVYKYFPSKEDLFSEVFNQ 57 TRE ++++A + F E+GF +T I I + G+A+G+ Y YF SKE++F E+ + Sbjct: 8 TRERIIKAAAKEFAEKGFYNTQISHIVESAGVARGTFYIYFKSKEEVFEEILKK 61 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.324 0.139 0.409 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 19,968,324 Number of extensions: 791030 Number of successful extensions: 2002 Number of sequences better than 1.0e-05: 27 Number of HSP's gapped: 2004 Number of HSP's successfully gapped: 27 Length of query: 295 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 189 Effective length of database: 26,153,027 Effective search space: 4942922103 Effective search space used: 4942922103 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.5 bits) S2: 115 (48.9 bits)