BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0091.0003.p (200 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH3769 [T] COG0394 Protein-tyrosine-phosphatase 107 1e-23 BS_ywlE [T] COG0394 Protein-tyrosine-phosphatase 92 5e-19 lin2684 [T] COG0394 Protein-tyrosine-phosphatase 88 1e-17 Cgl0344 [T] COG0394 Protein-tyrosine-phosphatase 78 9e-15 CAC2881 [T] COG0394 Protein-tyrosine-phosphatase 67 1e-11 >BH3769 [T] COG0394 Protein-tyrosine-phosphatase Length = 346 Score = 107 bits (267), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 5/192 (2%), Positives = 17/192 (8%), Gaps = 45/192 (23%) Query: 9 ILFVCTGNTCRSPMAEGLLRKLAKERGIDVEVRSAGVSAISGTSMSRHAAAILRDEGIHD 68 I + + D + A + + Sbjct: 6 IPHSSLEVSTLGLGTMTFGEQ--NSEA-DAHAQLDYAVAQGINLIDVAEMYPVPPRPETQ 62 Query: 69 QILSTQLNAETVAWADLVLTLTGGHKRHLLQYFPDAVA-KTYTLKEYVYDEEAVNADIRE 127 + T + + + + ++ Sbjct: 63 GLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKN------------- 109 Query: 128 LDSLYADAELSLALGGEPKSADLQRIIEIRQRIPSFDISDPFGGPREDYELAAAEIRTAL 187 Sbjct: 110 ------------IREAL----------------HDSLKRLQTDYLDLYQVHWPQRPTNCF 141 Query: 188 HSLLDKLESLRR 199 L Sbjct: 142 GKLGYSWTDSAP 153 >BS_ywlE [T] COG0394 Protein-tyrosine-phosphatase Length = 346 Score = 92.0 bits (227), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 6/109 (5%), Positives = 20/109 (18%) Query: 7 LHILFVCTGNTCRSPMAEGLLRKLAKERGIDVEVRSAGVSAISGTSMSRHAAAILRDEGI 66 + + + S + G + + D + A + + Sbjct: 1 MQYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPE 60 Query: 67 HDQILSTQLNAETVAWADLVLTLTGGHKRHLLQYFPDAVAKTYTLKEYV 115 + T + + + + L Sbjct: 61 TQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKN 109 >lin2684 [T] COG0394 Protein-tyrosine-phosphatase Length = 346 Score = 87.8 bits (216), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 6/181 (3%), Positives = 21/181 (11%), Gaps = 51/181 (28%) Query: 7 LHILFVCTGNTCRSPMAEGLLRKLAKERGIDVEVRSAGVSAISGTSMSRHAAAILRDEGI 66 + + + S + G + + + E + + Sbjct: 1 MQYHRIPHSSLEVSTLGLGTMTFGEQ----NSEADAHAQLDYAVAQGINLIDVAEMYPVP 56 Query: 67 HDQILSTQLNAETVAWADLVLTLTGGHKRHLLQYFPDAVAKTYTLKEYVYDEEAVNADIR 126 W + + K + + Sbjct: 57 PRPETQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQ---ALD------- 106 Query: 127 ELDSLYADAELSLALGGEPKSADLQRIIEIRQRIPSFDISDPFGGPREDYELAAAEIRTA 186 + L + Sbjct: 107 -------------------------------------RKNIREALHDSLKRLQTDYLDLY 129 Query: 187 L 187 Sbjct: 130 Q 130 >Cgl0344 [T] COG0394 Protein-tyrosine-phosphatase Length = 346 Score = 78.2 bits (191), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 11/184 (5%), Positives = 38/184 (20%), Gaps = 8/184 (4%) Query: 9 ILFVCTGNTCRSPMAEGLLRKLAKERGID-VEVRSAGVSAISGTSMSRHAAAILRDEGIH 67 +T + E + + + Sbjct: 7 PHSSLEVSTLGLGTMTFGEQ--NSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGL 64 Query: 68 D--QILSTQLNAETVAWADLVLTLTGGHKRHLLQYFPDAVAKTYTLKEYVYDEEA-VNAD 124 + + + + ++G + + PD ++E ++D + D Sbjct: 65 TETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTD 124 Query: 125 IRELDSLYADAELSLALGGEPKSADLQRI-IEIRQRIPSFDISDPFGGPREDYELAAAEI 183 +L ++ + G+ + G ++ Sbjct: 125 YLDLYQVHWPQRPT-NCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSNETA 183 Query: 184 RTAL 187 + Sbjct: 184 FGVM 187 >CAC2881 [T] COG0394 Protein-tyrosine-phosphatase Length = 346 Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 6/110 (5%), Positives = 23/110 (20%), Gaps = 4/110 (3%) Query: 7 LHILFVCTGNTCRSPMAEGLLRKLAKERGIDVEVRSAGVSAISGTSMSRHAAAILRDEGI 66 + + + S + G + + + + A++ A + Sbjct: 1 MQYHRIPHSSLEVSTLGLGTMTFGEQNSEA--DAHAQLDYAVAQGINLIDVAEMYPVPPR 58 Query: 67 HD--QILSTQLNAETVAWADLVLTLTGGHKRHLLQYFPDAVAKTYTLKEY 114 + + T + + + + L Sbjct: 59 PETQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRK 108 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.134 0.375 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 14,182,976 Number of extensions: 575180 Number of successful extensions: 1736 Number of sequences better than 1.0e-05: 21 Number of HSP's gapped: 1734 Number of HSP's successfully gapped: 21 Length of query: 200 Length of database: 38,378,431 Length adjustment: 101 Effective length of query: 99 Effective length of database: 26,729,697 Effective search space: 2646240003 Effective search space used: 2646240003 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 113 (48.1 bits)