BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0078.0027.p (595 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll5254 [V] COG1132 ABC-type multidrug transport system, ATPase ... 280 4e-75 SMb20813 [V] COG1132 ABC-type multidrug transport system, ATPase... 207 5e-53 BMEII0250 [V] COG1132 ABC-type multidrug transport system, ATPas... 205 2e-52 slr2019 [V] COG1132 ABC-type multidrug transport system, ATPase ... 202 1e-51 CC3420 [V] COG1132 ABC-type multidrug transport system, ATPase a... 197 5e-50 >mll5254 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 613 Score = 280 bits (717), Expect = 4e-75, Method: Compositional matrix adjust. Identities = 170/543 (31%), Positives = 295/543 (54%), Gaps = 5/543 (0%) Query: 53 GIDLPMLDFISELPQTSALAL--VLGAYVLIVLCQNLISRFVAIRNVDIQQSYSRQLRYE 110 + LP DF+ L L L VL A V +V Q +RF ++ + + +LR Sbjct: 66 AVRLPSNDFVRWLVPDGTLQLTTVLCALVGLVAVQAAFNRFKSVYMARLLFDFINRLRMN 125 Query: 111 VYGALLRAEWSFFLKKRTSDLINVMTTELARVLAGIXXXXXXXXXXXXXXVQIGFAFWLS 170 ++ ++ +A W F + R+SDL + +T ++ RV + + ++S Sbjct: 126 LFESIGKARWGVFSRMRSSDLDHALTGDIDRVQGAAFSLLMLVQIAVLLVGYLVISMFIS 185 Query: 171 PQMTXXXXXXXXXXXXFSRRFIRKAKRLGSRSSELGKQYLAGITDQLNGIKDIKSNNLEG 230 P MT + F +A G + + +++ L GIK KS N+E Sbjct: 186 PVMTAFAIVIGIMMFIALQPFRARATAFGRVLTSNRQDQYRTVSEFLGGIKVAKSLNVEA 245 Query: 231 SRLSWMHEFTDEVKKEQLDYTRLRTNSQLLYKMSSTLLIAMFIFVSFRFLHVEGPYLLLV 290 S + + +++K + +DY R + +++++S + +++FI+V+ ++ ++++ Sbjct: 246 SYFAQLQSTLEKMKADNIDYVRNSSIGTAVFQVASVVGLSLFIYVALVRFNLSLAEIVVL 305 Query: 291 ILVFARLWPTFSSLQTLLEQLASVLPSFKIXXXXXXXXXXXXXHGAHGESGVVPAPMALK 350 +LVF R+ P F +QT +Q+ LP++ G H +S + ++L Sbjct: 306 LLVFMRIAPRFMDMQTQAQQVLINLPAYTAMRSLQARFDAEREPG-HAQSEDMQ-KLSLD 363 Query: 351 HGLEARDVNFRYNPQEENYSLRGVDVVIPANRMTAIVGRSGAGKSTLVDLLMGLMQPESG 410 GL R V+F Y+ + + + +PA ++TA++G SG+GKST+ D+L+GL++P +G Sbjct: 364 TGLNIRGVSFSYDDSGKAV-VSDITFGLPAGKVTALIGPSGSGKSTIADMLLGLLEPTAG 422 Query: 411 EILADGEPVTGERLLPYRRSIGYVAQDPFLYNATIRDNLTMIKPDASEAELWEALEFASS 470 +IL DG + +R + YV QD FL + TI NL + P AS+ +LW L A + Sbjct: 423 KILVDGVEIDAGNRRRWRDQVAYVPQDVFLLHDTIAANLRLAAPQASDDDLWTVLRAAHA 482 Query: 471 ADFVRKLPQGLDTLLGDRGVRLSGGERQRLVLARAIIRKPSILVLDEATSALDTENEKRI 530 DFV +L Q L+T++GDRGVRLSGGERQR+ LARA++RKPS+L+LDEATSALD +N+ I Sbjct: 483 GDFVERLDQRLETVVGDRGVRLSGGERQRIALARALLRKPSLLILDEATSALDWQNQSLI 542 Query: 531 QEALERLKATVTVIVIAHRLSTIRGADQILVIDQGRVIQQGVYSGLASEKGGMFNRLLSS 590 +++ L+ +T++ IAHR S I AD ++ ++ GR+++ G Y L ++ +R+LS Sbjct: 543 ARSIDGLRGAMTILTIAHRPSMIAFADWVVAMEDGRIVEVGQYQRLKAKPASRLSRMLSG 602 Query: 591 QEE 593 ++ Sbjct: 603 EQS 605 >SMb20813 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 607 Score = 207 bits (526), Expect = 5e-53, Method: Compositional matrix adjust. Identities = 108/239 (45%), Positives = 160/239 (66%), Gaps = 2/239 (0%) Query: 353 LEARDVNFRYNPQEENYSLRGVDVVIPANRMTAIVGRSGAGKSTLVDLLMGLMQPESGEI 412 +E RDV F Y EE L+GV + + TA+VG SGAGKST++ L+ P+SG I Sbjct: 358 VEFRDVRFSYGNGEE--VLKGVSFLAEGGKTTALVGPSGAGKSTIISLIPRFYDPQSGVI 415 Query: 413 LADGEPVTGERLLPYRRSIGYVAQDPFLYNATIRDNLTMIKPDASEAELWEALEFASSAD 472 L DG+ + R + YV+Q +L+ +IRDN+ +P+A++AE+ EA A + D Sbjct: 416 LIDGQDIAAVTKQSLRNGLAYVSQQAYLFEGSIRDNIRYGRPEATDAEVEEAARLAYAHD 475 Query: 473 FVRKLPQGLDTLLGDRGVRLSGGERQRLVLARAIIRKPSILVLDEATSALDTENEKRIQE 532 F+ PQG DT +G++G+ LSGG+RQRL +ARA++R IL+LDEATSALDTE+E +Q+ Sbjct: 476 FILAQPQGYDTPVGEQGMTLSGGQRQRLSIARALVRNAPILLLDEATSALDTESEAAVQK 535 Query: 533 ALERLKATVTVIVIAHRLSTIRGADQILVIDQGRVIQQGVYSGLASEKGGMFNRLLSSQ 591 AL++ + TVIVIAHRLST+ AD+I+V+++G V+++G + LA G++ RL + Q Sbjct: 536 ALDQAMSGRTVIVIAHRLSTVVNADKIVVMNEGLVVEEGTHEELARRPDGVYARLHNIQ 594 >BMEII0250 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 611 Score = 205 bits (521), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 106/235 (45%), Positives = 153/235 (65%), Gaps = 2/235 (0%) Query: 357 DVNFRYNPQEENYSLRGVDVVIPANRMTAIVGRSGAGKSTLVDLLMGLMQPESGEILADG 416 ++ F YN + L GV + A TA+VG SGAGKSTL+ L+ + G IL DG Sbjct: 358 NIYFSYN--QTAPVLHGVTFMAKAGETTAVVGASGAGKSTLISLVQRFYDLDRGRILFDG 415 Query: 417 EPVTGERLLPYRRSIGYVAQDPFLYNATIRDNLTMIKPDASEAELWEALEFASSADFVRK 476 + + G R +I YV+Q P+L+ TI DN+ +PDAS+ E+ EA + A + +F+ + Sbjct: 416 QDIAGVTKQSLRHAIAYVSQQPYLFEGTIADNIRYGRPDASDEEIIEAAKLAHAHEFILQ 475 Query: 477 LPQGLDTLLGDRGVRLSGGERQRLVLARAIIRKPSILVLDEATSALDTENEKRIQEALER 536 PQG DT +G+ GV LSGG+RQR+ +ARAI+R +L+LDEATSALD E+EKR+Q+ALE Sbjct: 476 QPQGYDTPVGENGVTLSGGQRQRISIARAIVRNTPVLLLDEATSALDNESEKRVQQALET 535 Query: 537 LKATVTVIVIAHRLSTIRGADQILVIDQGRVIQQGVYSGLASEKGGMFNRLLSSQ 591 + T IVIAHRLST+ AD+I+V++ GRV+++G + L + G++ R Q Sbjct: 536 IMQNRTTIVIAHRLSTVVNADRIVVMEAGRVVEEGRHEDLIDIENGVYARFYQLQ 590 >slr2019 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 593 Score = 202 bits (514), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 154/502 (30%), Positives = 249/502 (49%), Gaps = 40/502 (7%) Query: 98 DIQQSYSRQLRYEVYGALLRAEWSFFLKKRTSDLINVMTTELARVLAGIXXXXXXXXXXX 157 ++ Q LR + Y L + + ++F ++ T L+ ++ ++ ++ + Sbjct: 97 NLAQDIQHDLRLDAYAHLQQLDLAYFEERSTGRLMAILNDDINQLERFLDVGANEILQVL 156 Query: 158 XXXVQIGFAFW-LSPQMTXXXXXXXXXXXXFSRRFIRKAKRLGSRSSELGKQYLAGITDQ 216 V IG AF+ ++P + S F S L +Y A + ++ Sbjct: 157 TTVVVIGGAFFVITPDIAWMAVVPMPFVLLGSIYF----------QSLLTSRY-ALVREK 205 Query: 217 LNGIKDIKSNNLEG--SRLSWMHEFTDEVKKEQLDYTRLRTNSQLLYKMSSTL--LIAMF 272 ++ + SNNL G + S+ E +EV++ + D R ++Q +S+ LI + Sbjct: 206 VSNLNSRLSNNLSGIMTIKSFATE-AEEVERLRQDSDAYRDSNQRAIALSAAFVPLIRVI 264 Query: 273 IFVSF------------RFLHVEGPYLLLVILVFARLWPTFSSLQTLLEQLASVLPSFKI 320 IF F R G Y +LV L LWP L L L ++ Sbjct: 265 IFAGFSTILYFGGLDAVRGNLAVGSYSMLVFLTQRLLWP--------LTGLGKTLDLYQR 316 Query: 321 XXXXXXXXXXXXXHGAHGESGVVP-APMALKHGLEARDVNFRYNPQEENYSLRGVDVVIP 379 G + P ++ L ++++F Y + L+ V + +P Sbjct: 317 AMASTQRVMQLLATPIQAHPGELSLHPSQVQGELVFQNISFAY--PHRSAVLKNVSLRVP 374 Query: 380 ANRMTAIVGRSGAGKSTLVDLLMGLMQPESGEILADGEPVTGERLLPYRRSIGYVAQDPF 439 A + IVG +G+GKSTLV LL+ L + +SG+IL DG + L RRS+G V+QD F Sbjct: 375 AGQTIGIVGATGSGKSTLVKLLLRLYEWDSGDILLDGVDLKKYFLGDLRRSVGLVSQDVF 434 Query: 440 LYNATIRDNLTMIKPDASEAELWEALEFASSADFVRKLPQGLDTLLGDRGVRLSGGERQR 499 L++ T+R+N+ DA+ A++ A A + +F+ +LPQG DT++G+RG +LSGG+RQR Sbjct: 435 LFHGTVRENIAYGSADATLAQIERAANLAEAEEFINQLPQGYDTIIGERGQKLSGGQRQR 494 Query: 500 LVLARAIIRKPSILVLDEATSALDTENEKRIQEALERLKATVTVIVIAHRLSTIRGADQI 559 L +ARAI++ P IL+LDEATSA+D E E I +LE++ T I IAHRLST+R ADQI Sbjct: 495 LAIARAILKNPPILILDEATSAVDNETEAAIVRSLEKITKNRTTITIAHRLSTVRYADQI 554 Query: 560 LVIDQGRVIQQGVYSGLASEKG 581 V++ G V + G + L + +G Sbjct: 555 YVLENGMVQEMGSHESLLAHQG 576 >CC3420 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 832 Score = 197 bits (500), Expect = 5e-50, Method: Compositional matrix adjust. Identities = 110/239 (46%), Positives = 159/239 (66%), Gaps = 10/239 (4%) Query: 353 LEARDVNFRYN----PQEENYSLRGVDVVIPANRMTAIVGRSGAGKSTLVDLLMGLMQPE 408 +E +DV FRY P + +SL+ + P R+ A+VG +G+GKST V L+ L + Sbjct: 592 IEFQDVTFRYKAAGAPLYDRFSLK----IAPGERV-ALVGPTGSGKSTFVKLIQRLHDLQ 646 Query: 409 SGEILADGEPVTGERLLPYRRSIGYVAQDPFLYNATIRDNLTMIKPDASEAELWEALEFA 468 G ++ DG+ V+ + RR+I V QDP L++ T+ +N+ KPDA+ E+ +A A Sbjct: 647 DGAVVIDGQDVSTVKQASLRRAIAVVPQDPALFHRTLFENIAYGKPDATREEVEDAAIKA 706 Query: 469 SSADFVRKLPQGLDTLLGDRGVRLSGGERQRLVLARAIIRKPSILVLDEATSALDTENEK 528 + +F+ +LP+G DTL+G+RGV+LSGGERQR+ +ARA + ILVLDEATS+LD E E Sbjct: 707 RAHEFILRLPKGYDTLVGERGVKLSGGERQRVAIARAFLADAPILVLDEATSSLDVETEG 766 Query: 529 RIQEALERLKATVTVIVIAHRLSTIRGADQILVIDQGRVIQQGVYSGLASEKGGMFNRL 587 +QEA E L T IVIAHRLST+RGAD+ILV GRV+++G ++ L + KGG++ RL Sbjct: 767 HVQEAAEALMEGRTTIVIAHRLSTVRGADRILVFQGGRVVEEGRHAEL-TAKGGVYARL 824 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.322 0.138 0.387 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 38,530,192 Number of extensions: 1608888 Number of successful extensions: 19027 Number of sequences better than 1.0e-05: 2125 Number of HSP's gapped: 16652 Number of HSP's successfully gapped: 2308 Length of query: 595 Length of database: 38,378,431 Length adjustment: 112 Effective length of query: 483 Effective length of database: 25,461,023 Effective search space: 12297674109 Effective search space used: 12297674109 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 119 (50.4 bits)