BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0078.0020.p
         (297 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

CAC0420 [R] COG1266 Predicted metal-dependent membrane protease        95   1e-19
CC2538 [R] COG1266 Predicted metal-dependent membrane protease         84   4e-16
YPO1140 [R] COG1266 Predicted metal-dependent membrane protease        50   4e-06

>CAC0420 [R] COG1266 Predicted metal-dependent membrane protease
          Length = 276

 Score = 94.7 bits (234), Expect = 1e-19,   Method: Compositional matrix adjust.
 Identities = 59/186 (31%), Positives = 97/186 (52%), Gaps = 4/186 (2%)

Query: 79  QPLSTIGLTRPD--VKRFAQGLLSGALLMAIIVMVLWALGNAVFQNEGWTPRFSQLDLPG 136
           + L ++G T+    +  F  GL+ GA+ M  + ++L A  NAVF      P  +   L  
Sbjct: 69  KSLQSMGFTKGKGSILSFVLGLVFGAVSMTAVFILLLATRNAVFLGNIINPNITNQTLKD 128

Query: 137 LVLTACIAGICEEALFRGYIQHLLTSRLGTVWAVVITSVLFSAAHMANPGYNWISALNIV 196
           L+L   + G  EE   RGY    ++ R   + A +ITS+LFS  H  NP    +  +N+V
Sbjct: 129 LIL-FILVGFAEEIFLRGYCLRSISERNKKITAAIITSLLFSVLHALNPNVTAVFFVNVV 187

Query: 197 LIALIFSWATLRAGNLYFAMALHLSWNLVQGYGFGVSVSGNIQQGLYSVMLEGPDWITGG 256
           LI ++FS+ T +  N++  +  H+ W+  +G  +G   SG I +G+Y++ + G + I GG
Sbjct: 188 LIGMLFSYMTFKF-NIWLPIGFHIMWDYFEGNVWGFPDSGMIVKGIYNIKILGSNVINGG 246

Query: 257 SFGLEA 262
             G E 
Sbjct: 247 LVGPEG 252


>CC2538 [R] COG1266 Predicted metal-dependent membrane protease
          Length = 309

 Score = 83.6 bits (205), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 69/193 (35%), Positives = 104/193 (53%), Gaps = 13/193 (6%)

Query: 83  TIGLTRPDVKRFAQGLLSGALLMAIIVMVLWALGNAVFQNEG-WTPRFSQLDLPGLVLTA 141
            +GL    V+R+  GLL G   +  ++ ++WA G    +  G WT     L LP L L A
Sbjct: 87  VLGLNGEFVRRYTWGLLVGCGFLLSVIGLIWATGGYRIEGFGVWTAPSPMLFLPILALFA 146

Query: 142 --CIAGICEEALFRGYIQHLLTSRLGTVWAVVITSVLFSAAHMAN--PGYN-WISALNIV 196
              I G  EE L RG++  L+ SR G V A+VI SVLF+  H  N  P     ++  N++
Sbjct: 147 GFVIQGGTEELLMRGWLMQLVASRHGLVIAIVINSVLFAILHGGNIAPSKELALALANLI 206

Query: 197 LIALIFSWATLRAGNLYFAMALHLSWNLVQGYGFGVSVSGNIQQGLYSVMLE------GP 250
           L  ++ S   ++ G+L+   A H +WN + G GFG+ VSG  +  + S++++       P
Sbjct: 207 LFGVMISLYAIKEGSLWGVCAWHTAWNWLLGVGFGLEVSGG-RMAVQSLVIDLAPKDGAP 265

Query: 251 DWITGGSFGLEAS 263
            W+TGG+FG EAS
Sbjct: 266 WWLTGGAFGPEAS 278


>YPO1140 [R] COG1266 Predicted metal-dependent membrane protease
          Length = 272

 Score = 50.4 bits (119), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 36/86 (41%), Positives = 51/86 (59%), Gaps = 8/86 (9%)

Query: 142 CIAGICEEALFRGYIQHLLTSRLGTVWAVVITSVLFSAAHMA-NPGYNWISALNIVLIAL 200
           C+A   EEALFRGY+Q  L   LG+  A+VIT++LF +AH A  P     +AL  V+  L
Sbjct: 182 CLA---EEALFRGYLQQRLGQWLGSYPALVITALLFGSAHFAGGPLLMLFAALAGVIYGL 238

Query: 201 IFSWATLRAGNLYFAMALHLSWNLVQ 226
            + W    +G L+ A+A H + NL+ 
Sbjct: 239 AWLW----SGRLWVAVAFHFALNLMH 260


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.327    0.139    0.435 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 19,539,905
Number of extensions: 673850
Number of successful extensions: 3025
Number of sequences better than 1.0e-05: 5
Number of HSP's gapped: 3026
Number of HSP's successfully gapped: 5
Length of query: 297
Length of database: 38,378,431
Length adjustment: 106
Effective length of query: 191
Effective length of database: 26,153,027
Effective search space: 4995228157
Effective search space used: 4995228157
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 115 (48.9 bits)