BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0078.0007.p (508 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH0793 [T] COG4753 Response regulator containing CheY-like recei... 246 4e-65 SPy1587 [T] COG4753 Response regulator containing CheY-like rece... 192 1e-48 BH2109 [T] COG4753 Response regulator containing CheY-like recei... 185 1e-46 SP0661 [T] COG4753 Response regulator containing CheY-like recei... 104 4e-22 BH1123 [T] COG4753 Response regulator containing CheY-like recei... 103 5e-22 >BH0793 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 508 Score = 246 bits (629), Expect = 4e-65, Method: Compositional matrix adjust. Identities = 171/522 (32%), Positives = 271/522 (51%), Gaps = 37/522 (7%) Query: 1 MYKVFIVDDEPFIIEGLYDIVDWAGMGMEIVGRAENGQEALEALTSLRADILITDISMPL 60 M +V +VDDEP I+EGL ++DW +G EIV A NG EALE + D+LITDI MP Sbjct: 1 MIRVMLVDDEPLILEGLKHLIDWGQLGYEIVATARNGVEALEIAKYVSFDLLITDIKMPE 60 Query: 61 MNGLDLIRAVRKLQPGMKVIILSGYDEFGYLKEGMTLGIENYLLKPINLEEFKATLSNTV 120 GL+LI A+ + + ++ I+LSG+ EF ++K+G+TLGIENYLLKPIN +E +TLS+ Sbjct: 61 KTGLELIAALNEREKTIRSIVLSGFQEFHFVKQGLTLGIENYLLKPINEKELISTLSHVK 120 Query: 121 EKLHMSRVEDELNAQSISILRDNIMHRWLREQIGANEFRERSELLG-IQLDKPXXXXXXX 179 EK++ + +++E S +LRD+ + RWL ++G EF++R +Q P Sbjct: 121 EKINHAFLKEE----STLVLRDHSIWRWLVGKMGHTEFKQRMAFYPEVQWKFPLRIGLLK 176 Query: 180 RPGKAAVGGEFLKAVSDALGDSRSAILFQDMEGDTVLL-HGLSEYQRGKEEVDRCHERLA 238 E + + L SA+ GD + + G +E R + + Sbjct: 177 MEWDQHTEEELYR-LQRTLEQETSAMTVVTPSGDLLFIWCGFERESDWGQERSR-FQSVV 234 Query: 239 MQLPSFHPLRFSLGSVVETEGGAALSYTQAKKAQEYFMLFPERTVICYEEIEHRSEAGGR 298 + P P F + Y + + E +L PER +++ + E+ Sbjct: 235 TEAPIGQPFVFVHSEPISEIQCLYEVYREMEMKCELKLLLPERDHHMADQLTFKRESELI 294 Query: 299 EVTLNWEQMQKLILAKDKEGLLQRIDERFEQL---RHMEGVTPEILQDFSMEWMIRFKMQ 355 +N +++ I Q++ + E + H E P L+ ME+ R K Q Sbjct: 295 PPQMNI-TLEQDIFEHLANRHYQKVRKDLEHMLSESHCER-NPIFLKSVLMEFFYRLKSQ 352 Query: 356 VKEIRHSEEPEIYQEGFRRLRETTSIHEWIHILKEAAAL-----TIDLLIRD-------V 403 I Q F + + + + +H+ + A+ IDLL D Sbjct: 353 F----------IVQLPFDQYVQI--VQQIVHVETTSEAMKMIDRCIDLLEDDHLQENEKN 400 Query: 404 KSPVVQQVLNFIHESYAEDISLKTLGAQFNIHPVYLGQLFSKEVGDTFTEYINRYRIEKA 463 SP++Q VL IH+ +++D+SLKTLG F+I+P+YLGQLF +EVG +FT+Y+N+ RI++A Sbjct: 401 YSPIIQTVLQHIHQHFSQDLSLKTLGHSFHINPIYLGQLFQREVGCSFTKYLNQLRIDRA 460 Query: 464 KEQLRGTSSKVHEIARNVGYWETGYFYKQFKKYVGISPTEYK 505 K+ L + + +I + VGY + YFYKQFKKY ++PTE++ Sbjct: 461 KKLLLNSYDRAGQIGKKVGYGDATYFYKQFKKYEAMTPTEWR 502 >SPy1587 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 494 Score = 192 bits (487), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 153/541 (28%), Positives = 257/541 (47%), Gaps = 97/541 (17%) Query: 1 MYKVFIVDDEPFIIEGLYDIVDWAGMGMEIVGRAENGQEALEALTSLRADILITDISMPL 60 MYKV +VDDE I++GL I+DW +G E+V A +G+EAL LT D++I+D++MP Sbjct: 1 MYKVLLVDDEYMILQGLTMIIDWQALGFEVVQTARSGKEALAYLTQYPVDVMISDVTMPG 60 Query: 61 MNGLDLIRAVRKLQPGMKVIILSGYDEFGYLKEGMTLGIENYLLKPINLEEFKATLSNTV 120 M GLDLI A + P ++ +ILSGY EF Y+++ M L + YLLKP++ E +A Sbjct: 61 MTGLDLIEAAKTYHPQLQTLILSGYQEFSYVQKAMELETKGYLLKPVDKAELQA------ 114 Query: 121 EKLHMSRVEDELNAQSISILR-----DNIMHRWLREQIGANEFRERSELLGIQLDKPXXX 175 M + +D L+AQ +R D+++ WL +++ EF++ S+ L Sbjct: 115 ---KMKQFKDWLDAQQAESIRQEAYHDSLLTLWLTDELSEKEFQQLSQGL---------- 161 Query: 176 XXXXRPGKAAVGGEFL-------KAVSDALGDSRSAILFQDMEGD-----TVLLHGLSEY 223 P A G L +A DA + + E D VLL + Sbjct: 162 -----PAAALTGFTVLYLDCQEWQAAIDAYFEREGQPFYLKKEEDKKVYLAVLLGKTDQA 216 Query: 224 QRGKEEVDRCHERLAMQLPSFHPLRFSLGSVVETEGGAALSYTQAKKAQEYFM-LFPERT 282 + ++ + R QL LG V+ SY Q K+ Y + P R Sbjct: 217 KAFTYDLQKRFSRNMHQL--------ILGETVDDWENVYESYNQVLKSLFYNCEVSPIRA 268 Query: 283 VICYEEIEHRSEAGGREVTLNWEQMQKLILAKDKEGLLQRIDERFEQLRHMEGVTPEILQ 342 + +S+ E L + K ++ D+ +L +++ F++++ + +PE Sbjct: 269 -------KDKSKIELPESRLQFFAFNKALMIGDEPTILSKLEAIFDEMKTL-NFSPE--- 317 Query: 343 DFSMEWMIRFKMQVKEIRHSEEPEIYQEGFRRLRETT--SIHEWIHILKEAAALTIDLLI 400 VK + +IY++ F L + T S+ + IH + +ID ++ Sbjct: 318 ------------DVKHVSFLLFSDIYRQ-FPILDKMTYLSMVKTIH-----DSQSIDCIL 359 Query: 401 RDVK----------------SPVVQQVLNFIHESYAEDISLKTLGAQFNIHPVYLGQLFS 444 R++K S +V + ++ I + Y ++++LK + + +++ VYLGQ F Sbjct: 360 RELKKVLDVTNQNNSPEKRYSDLVSETIDCIRKEYHQELTLKAIADRLHVNGVYLGQCFK 419 Query: 445 KEVGDTFTEYINRYRIEKAKEQLRGTSSKVHEIARNVGYWETGYFYKQFKKYVGISPTEY 504 E +FT+Y+N RI+KA++ L T+ ++EIA GY YF K FKK G+SP E+ Sbjct: 420 NETERSFTQYLNHVRIQKAQQLLLYTNQSINEIAYETGYNTNHYFIKMFKKLNGLSPKEF 479 Query: 505 K 505 + Sbjct: 480 R 480 >BH2109 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 525 Score = 185 bits (470), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 145/540 (26%), Positives = 252/540 (46%), Gaps = 53/540 (9%) Query: 1 MYKVFIVDDEPFIIEGLYDIVDWAGMGMEIVGRAENGQEALEALTSLRADILITDISMPL 60 MYKV + DDE F+ GL +++W G E+ A+NG++A + + ++ D++ITDI MP+ Sbjct: 1 MYKVLLADDEFFVRHGLKSLIEWEKCGYEVAAEADNGEDAFKLVQEIKPDLVITDIRMPV 60 Query: 61 MNGLDLIRAVRK-LQPGMKVIILSGYDEFGYLKEGMTLGIENYLLKPINLEEFKATLSNT 119 +GL LI+ V + L K II+SGY++F Y ++ + G +++LKPI+ +E +A L Sbjct: 61 FDGLQLIQKVNETLSFNTKFIIISGYNDFSYAQKAVRFGAVDFVLKPIDQDELEAALIKL 120 Query: 120 VEKLHMSRVEDELNAQSISILRDNIMHRWLREQIGANEFRERSELLGIQ----------- 168 L E N+ +L D I L E NE R + L I Sbjct: 121 AATLDQ---EKATNSDQEKVLLDQIFIHSLGENKKENEVRRWAAKLNINNRHFYYYLLLE 177 Query: 169 -----LDKPXXXXXXXRPGKAAVGGEFLKAVSDALGDSRSAILFQDMEGDTVLLHGLSEY 223 LDK P + + + V+ +++ ++ LL Sbjct: 178 VNNLSLDKGFINEQYKEPIRKVIR----ETVARQAATEEYTAIYEQLDHAYGLLITSEHL 233 Query: 224 QRGKEEVDRCHERLAMQLPSFH--PLRFSLGSVVETEGGAALSYTQAKKAQEYFMLFPER 281 ++ +++ E+L + F PL +G+ + SY A + Y +F E+ Sbjct: 234 KKFNGQIEPLAEKLRKDIQDFTNIPLTVYVGAKTDDLSTIKKSYETANSLRNYKYIFNEK 293 Query: 282 TVICYEEIEH----RSEAGGREVTLNWEQMQKLILAKDKEGLLQRIDERFEQLRHMEGVT 337 V +E+ E E EQM++ + + ++ ID+ F + + + V Sbjct: 294 NVFIHEQTESVDTTYDELNNHLFVTLMEQMEE----NNSDRIVNIIDKIFSEFQTKKFV- 348 Query: 338 PEILQDFSMEWMIRFKMQVKEIRHSEEPEI-----------YQEGFRRLRETTSIHEWIH 386 P ++ S+ + MQ + + +I Y F +L++ + Sbjct: 349 PSAVKT-SVNRCVHKVMQTVQAMEGDTGKIISAQAMTNWESYNLTFDQLKQV-----FTK 402 Query: 387 ILKEAAALTIDLLIRDVKSPVVQQVLNFIHESYAEDISLKTLGAQFNIHPVYLGQLFSKE 446 + EAA + +L ++KS + + V +I Y E+ISLK++ + F ++PVY+GQLF K Sbjct: 403 FVLEAAVIIQELRKENMKSDIYK-VKTYIENHYHENISLKSIASLFYMNPVYMGQLFKKT 461 Query: 447 VGDTFTEYINRYRIEKAKEQLRGTSSKVHEIARNVGYWETGYFYKQFKKYVGISPTEYKG 506 G F EY+ + R+ +AK+ LR T +V+E+A VG+ T YF QF+K ++PTEY+ Sbjct: 462 FGVYFKEYLLKLRMNEAKKLLRQTDMRVYEVAERVGFGSTDYFVTQFEKINKMTPTEYRN 521 >SP0661 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 245 Score = 104 bits (259), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 50/131 (38%), Positives = 83/131 (63%) Query: 2 YKVFIVDDEPFIIEGLYDIVDWAGMGMEIVGRAENGQEALEALTSLRADILITDISMPLM 61 Y + IV+DE + +GL +V+ A MEI+G+AENG++A E + DI++TDI+MP + Sbjct: 3 YTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWELIQKQVPDIILTDINMPHL 62 Query: 62 NGLDLIRAVRKLQPGMKVIILSGYDEFGYLKEGMTLGIENYLLKPINLEEFKATLSNTVE 121 NG+ L VR+ P + ++ L+GYD+F Y + LG+++YLLKP + ++ + L + Sbjct: 63 NGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDDYLLKPFSRQDIEEMLGKIKQ 122 Query: 122 KLHMSRVEDEL 132 KL E++L Sbjct: 123 KLDKEEKEEQL 133 Score = 66.6 bits (161), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 37/109 (33%), Positives = 63/109 (57%), Gaps = 3/109 (2%) Query: 397 DLLIRDVKSPVVQQVLNFIHESYAEDISLKTLGAQFNIHPVYLGQLFSKEVGDTFTEYIN 456 DLL + + Q++ + + +S SLK+L + P YL L KE+G F +Y+ Sbjct: 135 DLLTNRFEGNMAQKIQSHLADS---QFSLKSLASDLGFSPTYLSSLIKKELGLPFQDYLV 191 Query: 457 RYRIEKAKEQLRGTSSKVHEIARNVGYWETGYFYKQFKKYVGISPTEYK 505 R R+++AK L T K++EIA VG+ + YF ++FK+ G++P ++K Sbjct: 192 RERVKQAKLLLLTTDLKIYEIAEKVGFEDMNYFTQRFKQIAGVTPRQFK 240 >BH1123 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 526 Score = 103 bits (258), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 49/123 (39%), Positives = 76/123 (61%) Query: 1 MYKVFIVDDEPFIIEGLYDIVDWAGMGMEIVGRAENGQEALEALTSLRADILITDISMPL 60 M+KV I+DDE ++ GL I+ W +G E VG A NG+ L+ + I++TDI MP+ Sbjct: 1 MWKVVIIDDEEHVVRGLKKIISWKALGCECVGEAANGRRGLDIVRETSPHIVLTDIYMPI 60 Query: 61 MNGLDLIRAVRKLQPGMKVIILSGYDEFGYLKEGMTLGIENYLLKPINLEEFKATLSNTV 120 M GLD+I+ +R+ +V+ILSGY EF + ++ M L I +YL KP +++ + L + Sbjct: 61 MYGLDMIQILREDGFDGEVVILSGYSEFEHARKAMQLNITDYLSKPASVDTIETVLKRVI 120 Query: 121 EKL 123 KL Sbjct: 121 NKL 123 Score = 79.0 bits (193), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 36/95 (37%), Positives = 61/95 (64%) Query: 407 VVQQVLNFIHESYAEDISLKTLGAQFNIHPVYLGQLFSKEVGDTFTEYINRYRIEKAKEQ 466 +++QV+ +I + AE+I+L+ + + I YLGQ+F K VG++F Y+ R R+EKAK+ Sbjct: 425 LIEQVMIYIEKHLAENITLQDIADELYISRNYLGQIFKKVVGESFKNYVTRLRMEKAKKM 484 Query: 467 LRGTSSKVHEIARNVGYWETGYFYKQFKKYVGISP 501 ++ + ++E++ VGY YF FKKY G +P Sbjct: 485 IQEGNFLIYEVSEKVGYVNPAYFTTMFKKYTGYTP 519 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.320 0.137 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 37,477,934 Number of extensions: 1492709 Number of successful extensions: 5182 Number of sequences better than 1.0e-05: 347 Number of HSP's gapped: 5278 Number of HSP's successfully gapped: 358 Length of query: 508 Length of database: 38,378,431 Length adjustment: 111 Effective length of query: 397 Effective length of database: 25,576,357 Effective search space: 10153813729 Effective search space used: 10153813729 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 118 (50.1 bits)