BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0073.0015.p (601 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH1909 [T] COG2972 Predicted signal transduction protein with a ... 490 e-138 BH2110 [T] COG2972 Predicted signal transduction protein with a ... 234 3e-61 BS_yesM [T] COG2972 Predicted signal transduction protein with a... 147 6e-35 lin2119 [T] COG2972 Predicted signal transduction protein with a... 144 3e-34 BH0792 [T] COG2972 Predicted signal transduction protein with a ... 136 9e-32 >BH1909 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain Length = 597 Score = 490 bits (1262), Expect = e-138, Method: Compositional matrix adjust. Identities = 256/598 (42%), Positives = 388/598 (64%), Gaps = 4/598 (0%) Query: 7 MYARIITSMNNLRLRTKLFLSFGCVALIPVLIVGVFLTSELRNMAMDNALKQITANVDRV 66 MY+ +I ++N+++LR KL F V P++IVG+FLT+ELR+ A+ +A++Q NV+RV Sbjct: 1 MYSTLIQTINDMKLRDKLMFMFVVVVFFPMMIVGIFLTNELRSNAIQDAIQQSRVNVERV 60 Query: 67 KKRTGELLDVPLDIAYRLSNDSRLEEAANHRYVSVYDVVQAYWNYPDFREFVRLYREISS 126 K+RT E+L+VP+ IA L D R E N Y + YDVV AY Y +F +++ Y EI + Sbjct: 61 KERTTEVLNVPVLIANNLQFDERFIELVNQEYETTYDVVDAYLQYMNFTNYLQYYSEIHN 120 Query: 127 IRLYIDNPTVLDNWEFLQADGTVTQEPWYRTALAQKGMVCWNYIRD-NRDGRYYLSLIRK 185 ++ Y +N ++++NW + + +E W++ A+A W Y+ D + + YLS++++ Sbjct: 121 MKYYSENTSLMNNWVIIPVEHEAGEE-WFKEAMADPAYYRWFYLEDETKKNQAYLSMVKR 179 Query: 186 VNFFKQRTSGVLVVNVNTDRLNGILNQESFETLIVDENDNIVASNRTELLGQTLND-LNF 244 +NF + ++GVLV+ V+ +L+ IL QESF T+IVDE + I A+N+ E +G+ L++ ++F Sbjct: 180 LNFLEYGSAGVLVITVDPRKLDRILQQESFTTMIVDERNRIAATNQREYIGKDLHEVIDF 239 Query: 245 KAESAAGPGFYDVSIDGKPFTMLIDDWQPGGSLNSLRIISIFSVESIVKEPNRXXXXXXX 304 GP Y+ ++G+P +++D S + L+IISI + E I+K+ R Sbjct: 240 HEMIQEGPAIYEGKMNGEPSQIIVDYLTLQMSQSELKIISIVTKEHIMKDAKRLSIMGAT 299 Query: 305 XXXXXXXXXXXXXYYFSRLLTGRMLQLSKHISKVGSGNLGATLVIDGKDEIGQLARQFNH 364 +FS L++ R+ LS+ I++V SG+L +V+DGKDEIGQL+ QFN Sbjct: 300 VTMGGMAVAVLLIVHFSWLISKRLSHLSERINQVASGDLKTKIVVDGKDEIGQLSVQFNQ 359 Query: 365 MVRNINDLMSEVQESNRQKNAILLKQNEIKFKMMASQINPHFLFNALESIRMKAHVRGQA 424 MV N+ L+ +V E+NRQK + QNEIK KM+ASQINPHFLFN LESIRMK+H++G+ Sbjct: 360 MVANLRSLIHQVHETNRQKRLLEKSQNEIKLKMLASQINPHFLFNTLESIRMKSHMKGET 419 Query: 425 DISQVVRLLGKMMRKNLEVGNRRISLQSELETVSCYLVIQKFRYDDRLAYELHIDPKANL 484 +I++VV+ LGK+MRK+LEV I L++EL+ V CYL IQ FRY DRL YEL+IDP++ + Sbjct: 420 EIAKVVKQLGKLMRKSLEVTGHHIPLRNELDMVRCYLEIQTFRYGDRLHYELYIDPQSEM 479 Query: 485 VQIPPLIIQPLVENSVVHGLENRIDGGMVRVDIRIEDGLLKVQVSDNGAGISKTRMHEIR 544 V+I PLIIQPLVEN+V+HGLE DGG V + + L V V+D+G G+ + ++ I+ Sbjct: 480 VEILPLIIQPLVENAVIHGLERTEDGGTVTISTIVNGNDLTVIVNDDGCGMDEEKLEAIQ 539 Query: 545 QMLESKDDYESNNIGMRNIHLRLKLTYGPECGLTLASQEGFGTQISFEIP-LRSDSYV 601 ML + + N IG+ N+H RL+LTYG GL + S +G GT + F I +R D V Sbjct: 540 NMLHHPQEVDGNKIGLLNVHKRLQLTYGKTSGLIIESAKGKGTCVRFTISQIRGDDDV 597 >BH2110 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain Length = 585 Score = 234 bits (597), Expect = 3e-61, Method: Compositional matrix adjust. Identities = 162/593 (27%), Positives = 300/593 (50%), Gaps = 34/593 (5%) Query: 14 SMNNLRLRTKLFLSFGCVALIPVLIVGVFLTSELRNMAMDNALKQITANVDRVKKRTGEL 73 S+NN++LR KL L + +P+L+ + + N + I VD++ Sbjct: 7 SLNNVKLRNKLLLLYIFCVFLPILLTNIIFYNVTANNIKAQKMDDIELVVDQITNEFNNA 66 Query: 74 LDVPLDIAYRLSNDSRLEEAANHRYVSVYDVVQAYWNY-PDFREFVRLYREISSIRLYID 132 +D + I+ ++R+ + Y + D ++AY Y ++ F LY I SI Y D Sbjct: 67 VDQAIGISSGFYTNTRIYDFFETEYETAIDYIEAYDFYLREYSRFSPLYYSIQSISFYTD 126 Query: 133 NPTVLDNWEFLQADGT------VTQEPWYRTALAQKGMVCWNYIRDNRDGRYYL-SLIRK 185 NP+ F+ A G +E WYR + IR N L S+IR+ Sbjct: 127 NPS------FIYAGGIRPLTEHTKEEKWYRLLTEANHPII---IRTNPATDSGLFSVIRE 177 Query: 186 VNFFKQRTSGVLVVNVNTDRLN--GILNQESF--ETLIVDENDNIVASNRTELLGQTLND 241 +++ K + + +V ++ + L I N +F E +++ NI S+ E+ +T Sbjct: 178 LDYHKNKYNHKKIVRIDLNPLTIKQIFNNAAFTGEVYLLNGERNIEFSSNEEVNWRT-EQ 236 Query: 242 LNFKAESAAGPGFYDVSIDGKPFTMLIDDWQPGGSLNSLRIISIFSVESIVKEPNRXXXX 301 L+F A F + +I K ML ++ G R+ S I++E + Sbjct: 237 LHFDALE-----FPEDTIFTKE-RMLSQNYLEG-----WRVAGTISENEILEELYKSREF 285 Query: 302 XXXXXXXXXXXXXXXXYYFSRLLTGRMLQLSKHISKVGSGNLGATLVIDGKDEIGQLARQ 361 S+ + R+L++ KH+ ++ KDEIG+L + Sbjct: 286 IVILASINLLFPTLLIVLISKSIHSRLLRVLKHMKRMKKQKFDIINFPGDKDEIGELTNE 345 Query: 362 FNHMVRNINDLMSEVQESNRQKNAILLKQNEIKFKMMASQINPHFLFNALESIRMKAHVR 421 FN M + IN L++EV SN +K + L++ + + + SQINPHFLFNALE+IRM++ ++ Sbjct: 346 FNKMSQTINRLINEVYASNIEKKDLQLREKQAQLSALQSQINPHFLFNALETIRMRSMIK 405 Query: 422 GQADISQVVRLLGKMMRKNLEVGNRRISLQSELETVSCYLVIQKFRYDDRLAYELHIDPK 481 G+ + +++++ + K+ R +L G ++++ EL + C+L IQK+R+ D++ YEL ID + Sbjct: 406 GEKETAKIIQNMAKIFRNSLTWGKDWVTVRDELCLIICFLEIQKYRFGDKMEYELDIDEE 465 Query: 482 ANLVQIPPLIIQPLVENSVVHGLENRIDGGMVRVDIRIEDGLLKVQVSDNGAGISKTRMH 541 A IP ++ P VEN+ +HG+E+ + G++++ + DG + ++SDNGAG+ + ++ Sbjct: 466 AYDYIIPNMVFLPFVENASIHGIESVKEKGIIQIRVEKNDGEIVYEISDNGAGMDEEKLA 525 Query: 542 EIRQMLESKDDYESNNIGMRNIHLRLKLTYGPECGLTLASQEGFGTQISFEIP 594 + + L+++++ N+G++N++ RLKL Y ++ S+ G GT + ++P Sbjct: 526 SLIETLKNEENM-GENVGIKNVYYRLKLHYKNHFDFSINSRPGQGTTVQIKLP 577 >BS_yesM [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain Length = 577 Score = 147 bits (370), Expect = 6e-35, Method: Compositional matrix adjust. Identities = 87/247 (35%), Positives = 135/247 (54%), Gaps = 17/247 (6%) Query: 352 KDEIGQLARQFNHMVRNINDLMSEVQESNRQKNAILLKQNEIKFKMMASQINPHFLFNAL 411 +DE G L R F M++ IN+LM E N +K I+ E + K + +QINPHFL+N L Sbjct: 346 QDEAGMLNRHFTVMMKRINELMEE----NVEKQLII---KETELKALQAQINPHFLYNTL 398 Query: 412 ESIRMKAHVRGQADISQVVRLLGKMMRKNLEVGNRRISLQSELETVSCYLVIQKFRYDDR 471 ESI A Q IS++V LG ++R ++ + +++Q E + V Y+ IQ+FR+++R Sbjct: 399 ESINWLAKANQQKQISKMVESLGFLLRNSIHMKKDIVTIQEEADIVRHYMTIQRFRFEER 458 Query: 472 LAYELHIDPKANLVQIPPLIIQPLVENSVVHGLENRIDGGMVRVDIRIEDGLLKVQVSDN 531 L + L ID + IP L +QPL EN++ + LE +R+ + G + + V DN Sbjct: 459 LKFTLDIDDEVKHCLIPKLTLQPLAENAIQYALEPFTRPCAIRIQAKKAKGCVCITVEDN 518 Query: 532 GAGISKTRMHEIRQMLESKDDYESNNIGMRNIHLRLKLTYGPECGLTLASQEGFGTQISF 591 G G+ ++LES IG+ NI R+ LT+G GL + S+ GT+I Sbjct: 519 GPGMDG-------RILESTG---GRGIGLWNIRERISLTFGEPYGLRIHSEHEKGTRIVI 568 Query: 592 EIPLRSD 598 IP R++ Sbjct: 569 TIPCRNE 575 >lin2119 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain Length = 577 Score = 144 bits (364), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 83/276 (30%), Positives = 154/276 (55%), Gaps = 14/276 (5%) Query: 321 SRLLTGRMLQLSKHISKVGSGNLGATLVIDGK-DEIGQLARQFNHMVRNINDLMSEVQES 379 SR + R+L + +++V +G L A L +D DE+ ++ +FNHM N++ + +V Sbjct: 307 SRRYSKRILTIIGGMNRVENGTLDAKLPVDNNGDELTMISERFNHMTENLDAYVKKVY-- 364 Query: 380 NRQKNAILLKQNEIKFKMMASQINPHFLFNALESIRMKAHVRGQADISQVVRLLGKMMRK 439 ++ +++ + + K + Q+ PHFL+N+LE+IRM A V G + S ++ L ++R Sbjct: 365 -----SLEMEEQKARLKALQGQMQPHFLYNSLEAIRMNARVEGAKETSDMIYQLATLLR- 418 Query: 440 NLEVGNRRI-SLQSELETVSCYLVIQKFRYDDRLAYELHIDPKANLVQIPPLIIQPLVEN 498 +R I +L E+ V Y+ + R++ + E+HI+ + N IP +QPL+EN Sbjct: 419 -YTANHREITTLGEEINYVKQYVRFMEMRHEQPIKLEIHIEKRFNHTHIPRFALQPLIEN 477 Query: 499 SVVHGLENRIDGGMVRVDIRIEDGLLKVQVSDNGAGISKTRMHEIRQMLESKDDYESNNI 558 + + +V + + E+ L+ Q+ DNG G+ ++ E++ +ESK E+++I Sbjct: 478 FFKYAYKEN-QHPVVTITVTAENNNLQFQIKDNGKGMDAEKLKEVQATIESKA--ETSHI 534 Query: 559 GMRNIHLRLKLTYGPECGLTLASQEGFGTQISFEIP 594 G+ N++ RL+L YG LT+ S+ GT I F++P Sbjct: 535 GLANLNKRLQLLYGEAYSLTITSKPNEGTIILFQVP 570 >BH0792 [T] COG2972 Predicted signal transduction protein with a C-terminal ATPase domain Length = 587 Score = 136 bits (343), Expect = 9e-32, Method: Compositional matrix adjust. Identities = 77/270 (28%), Positives = 150/270 (55%), Gaps = 10/270 (3%) Query: 327 RMLQLSKHISKVGSGNLGATLVIDG-KDEIGQLARQFNHMVRNINDLMSEVQESNRQKNA 385 R+ L + + +V SG L + D++ ++ FN + + D + +V S Sbjct: 313 RVNDLVQTMKEVQSGQLSVRIETGNVDDDLAMISNTFNETLDELEDYIEKVYFSK----- 367 Query: 386 ILLKQNEIKFKMMASQINPHFLFNALESIRMKAHVRGQADISQVVRLLGKMMRKNLEVGN 445 LKQ E + + SQINPHFL+N LE+IRMK+ G ++++ L + R +L+ + Sbjct: 368 --LKQTEAELANLQSQINPHFLYNTLEAIRMKSLSEGGRTTAKMIVQLSYLFRYSLKSAD 425 Query: 446 RRISLQSELETVSCYLVIQKFRYDDRLAYELHIDPKANLVQIPPLIIQPLVENSVVHGLE 505 +++ EL+ V Y+ + R+ ++L +++ ++ K +PP I+QPL+EN ++HG + Sbjct: 426 L-VTIGDELQHVEQYVELFNIRFPNQLTFQVAVEEKHKHYVVPPFILQPLIENFLIHGFK 484 Query: 506 NRIDGGMVRVDIRIEDGLLKVQVSDNGAGISKTRMHEIRQMLESKDDYESNNIGMRNIHL 565 D + + I+ ++ L++Q+ DNG GI + ++ EI + L ++ S++IG+ N++ Sbjct: 485 RERDDNQINIIIQEKEQTLQIQIMDNGKGIPRKKVEEINERLSMTEN-SSHSIGLFNVNQ 543 Query: 566 RLKLTYGPECGLTLASQEGFGTQISFEIPL 595 RL+L YG G+++ S+ T ++ P+ Sbjct: 544 RLRLRYGERFGVSVQSEPDVCTIVTIRTPM 573 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.138 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 38,650,700 Number of extensions: 1556547 Number of successful extensions: 5394 Number of sequences better than 1.0e-05: 597 Number of HSP's gapped: 5351 Number of HSP's successfully gapped: 597 Length of query: 601 Length of database: 38,378,431 Length adjustment: 112 Effective length of query: 489 Effective length of database: 25,461,023 Effective search space: 12450440247 Effective search space used: 12450440247 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 119 (50.4 bits)