BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0073.0014.p (516 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH1910 [T] COG4753 Response regulator containing CheY-like recei... 283 3e-76 BH2109 [T] COG4753 Response regulator containing CheY-like recei... 164 2e-40 BH0793 [T] COG4753 Response regulator containing CheY-like recei... 109 1e-23 SPy1587 [T] COG4753 Response regulator containing CheY-like rece... 103 5e-22 SP0156 [T] COG4753 Response regulator containing CheY-like recei... 96 1e-19 >BH1910 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 506 Score = 283 bits (725), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 175/514 (34%), Positives = 282/514 (54%), Gaps = 19/514 (3%) Query: 1 VLIVDDELAIREGLATLLDWESLGYVVVDTAANAIEAKHKYELHSPDLMIIDIRMPGRDG 60 V+IVDDE +REGL L+ WE G+ V+DTA N E KY SPDLMI+DIRMP DG Sbjct: 4 VMIVDDEAMVREGLKALISWEEYGFRVIDTARNGKEGFTKYRQLSPDLMIVDIRMPEVDG 63 Query: 61 LELIKELREDDPELHIIILSGYADFSYAKRAMSLGIDNYLLKPVDEDELHLYLTNLSAEL 120 L LI+ +R +D +H IILSG++DF+YAK+A+ D+YLLKP+DEDEL L + + Sbjct: 64 LSLIESIRAEDSAIHFIILSGHSDFNYAKKALGCQCDDYLLKPLDEDELIDSLKKVYGRI 123 Query: 121 AARAVYRKKDAAVKIWSREMLVQSLLLDNGPQAPAALEGPAMESGLLWDSYQVVLIRLLL 180 + V+ EM++ LL + P + + E YQV L+ Sbjct: 124 TRHHQVHELVERVQEKQVEMVLTELL-EGTPLSEIPI---GKEHNFFATDYQVALV---- 175 Query: 181 QDNADNGPSTAVKTRLAASFEEQEWGIVFSLDSYLGVLLQPSYQKELVRQLMVRNIWEAV 240 +N K +L EEQE G V Y+ ++ + + ++ + + + Sbjct: 176 ----ENRQDRLTK-QLKRLIEEQEEGYVIPFPEYIVIVCKNRFLQKRGKDHRYHLFAKWL 230 Query: 241 TAQGLECIITAGDMVDSLEEVPASKESALARMKEHFFYDEPGMIGPDSLKLKTGLPVKPE 300 + L AG V +L ++ S +SA ++ FF ++ + D L ++ KPE Sbjct: 231 EEEELHA--CAGSKVVNLADIYESYQSAKRLYEKKFFVEKGRLFTADQLVDRS----KPE 284 Query: 301 EVEPGLAPVTERLYFAMDIGSLNLLPSLIQEAGALMIAAGYSEMAVKSRYVRLVTHLMNK 360 E L +RLY+++DIG++ ++I+E ++I E +K +L ++++++ Sbjct: 285 APEFSLESYADRLYYSIDIGNMEGCVAIIEELKNVVIVHLQEEKEIKVALFQLYSNILHQ 344 Query: 361 LSLQYRELELLHSRMDEQVEQIYKHTSLPKLQSHINVLLEQYAGGIKRDDMEVLIKRMLD 420 L + +E + + IY+ LP + + + L+ + ++L+++M+ Sbjct: 345 LVRSHPNMEGVLEPLVMNAGDIYQFEHLPGIMAFLTKQLKYVIDCMDNGQPDLLLRKMIA 404 Query: 421 LIHRHYPENLKLETLADVFTYSSAYLGKLFKSSTGLSFNSYLDNIRIGKAKELLDQGYKI 480 LIH+ Y +NL+LETLA VF Y+ AYLGKLFK+ TG FN+YLD +RI K LL +GYK+ Sbjct: 405 LIHKDYAKNLRLETLASVFNYNRAYLGKLFKNYTGEYFNTYLDKVRIENGKRLLQKGYKV 464 Query: 481 HQAASEVGFSDVDYFREKFKKIEGLSPSDYRRKN 514 ++ A ++G+++VDYF KFKK G+SPS +R+++ Sbjct: 465 YEVAEKIGYANVDYFHRKFKKYVGVSPSTFRKRH 498 >BH2109 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 525 Score = 164 bits (416), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 141/560 (25%), Positives = 261/560 (46%), Gaps = 88/560 (15%) Query: 1 VLIVDDELAIREGLATLLDWESLGYVVVDTAANAIEAKHKYELHSPDLMIIDIRMPGRDG 60 VL+ DDE +R GL +L++WE GY V A N +A + PDL+I DIRMP DG Sbjct: 4 VLLADDEFFVRHGLKSLIEWEKCGYEVAAEADNGEDAFKLVQEIKPDLVITDIRMPVFDG 63 Query: 61 LELIKELRED-DPELHIIILSGYADFSYAKRAMSLGIDNYLLKPVDEDELHLYLTNLSAE 119 L+LI+++ E II+SGY DFSYA++A+ G +++LKP+D+DEL L L+A Sbjct: 64 LQLIQKVNETLSFNTKFIIISGYNDFSYAQKAVRFGAVDFVLKPIDQDELEAALIKLAAT 123 Query: 120 LAARAVY-------------------RKKDAAVKIWSREMLVQS------LLLDNGPQAP 154 L KK+ V+ W+ ++ + + LLL+ Sbjct: 124 LDQEKATNSDQEKVLLDQIFIHSLGENKKENEVRRWAAKLNINNRHFYYYLLLE------ 177 Query: 155 AALEGPAMESGLLWDSYQVVLIRLLLQDNADNGPSTAVKTRLAASFEEQEWGIVFSLDSY 214 + +++ G + + Y+ + +++ + A R AA+ E+ I LD Sbjct: 178 --VNNLSLDKGFINEQYKEPIRKVIRETVA----------RQAAT--EEYTAIYEQLDHA 223 Query: 215 LGVLLQPSYQKELVRQL-----MVRNIWEAVTAQGLECIITAGDMVDSLEEVPASKESAL 269 G+L+ + K+ Q+ +R + T + + G D L + S E+A Sbjct: 224 YGLLITSEHLKKFNGQIEPLAEKLRKDIQDFT--NIPLTVYVGAKTDDLSTIKKSYETAN 281 Query: 270 ARMKEHFFYDEPGMIGPDSLKLKTGLPVKPEEVEPGLAPVTERLYFA----MDIGSLNLL 325 + + ++E + + + E V+ + L+ M+ + + + Sbjct: 282 SLRNYKYIFNEKNVF----------IHEQTESVDTTYDELNNHLFVTLMEQMEENNSDRI 331 Query: 326 PSLIQEAGALMIAAGYSEMAVKSRYVRLVTHLMNK-----------LSLQYRELELLHSR 374 ++I + + + AVK+ R V +M +S Q ++ Sbjct: 332 VNIIDKIFSEFQTKKFVPSAVKTSVNRCVHKVMQTVQAMEGDTGKIISAQAMTNWESYNL 391 Query: 375 MDEQVEQIYKHTSLPKLQSHINVLLEQYAGGIKRDDMEVLIKRMLDLIHRHYPENLKLET 434 +Q++Q++ K V++++ +++++M+ I ++ I HY EN+ L++ Sbjct: 392 TFDQLKQVF-----TKFVLEAAVIIQE----LRKENMKSDIYKVKTYIENHYHENISLKS 442 Query: 435 LADVFTYSSAYLGKLFKSSTGLSFNSYLDNIRIGKAKELLDQG-YKIHQAASEVGFSDVD 493 +A +F + Y+G+LFK + G+ F YL +R+ +AK+LL Q ++++ A VGF D Sbjct: 443 IASLFYMNPVYMGQLFKKTFGVYFKEYLLKLRMNEAKKLLRQTDMRVYEVAERVGFGSTD 502 Query: 494 YFREKFKKIEGLSPSDYRRK 513 YF +F+KI ++P++YR K Sbjct: 503 YFVTQFEKINKMTPTEYRNK 522 >BH0793 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 508 Score = 109 bits (273), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 54/109 (49%), Positives = 75/109 (68%) Query: 1 VLIVDDELAIREGLATLLDWESLGYVVVDTAANAIEAKHKYELHSPDLMIIDIRMPGRDG 60 V++VDDE I EGL L+DW LGY +V TA N +EA + S DL+I DI+MP + G Sbjct: 4 VMLVDDEPLILEGLKHLIDWGQLGYEIVATARNGVEALEIAKYVSFDLLITDIKMPEKTG 63 Query: 61 LELIKELREDDPELHIIILSGYADFSYAKRAMSLGIDNYLLKPVDEDEL 109 LELI L E + + I+LSG+ +F + K+ ++LGI+NYLLKP++E EL Sbjct: 64 LELIAALNEREKTIRSIVLSGFQEFHFVKQGLTLGIENYLLKPINEKEL 112 Score = 86.7 bits (213), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 39/100 (39%), Positives = 65/100 (65%), Gaps = 1/100 (1%) Query: 414 LIKRMLDLIHRHYPENLKLETLADVFTYSSAYLGKLFKSSTGLSFNSYLDNIRIGKAKEL 473 +I+ +L IH+H+ ++L L+TL F + YLG+LF+ G SF YL+ +RI +AK+L Sbjct: 404 IIQTVLQHIHQHFSQDLSLKTLGHSFHINPIYLGQLFQREVGCSFTKYLNQLRIDRAKKL 463 Query: 474 LDQGY-KIHQAASEVGFSDVDYFREKFKKIEGLSPSDYRR 512 L Y + Q +VG+ D YF ++FKK E ++P+++R+ Sbjct: 464 LLNSYDRAGQIGKKVGYGDATYFYKQFKKYEAMTPTEWRK 503 >SPy1587 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 494 Score = 103 bits (258), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 54/123 (43%), Positives = 76/123 (61%) Query: 1 VLIVDDELAIREGLATLLDWESLGYVVVDTAANAIEAKHKYELHSPDLMIIDIRMPGRDG 60 VL+VDDE I +GL ++DW++LG+ VV TA + EA + D+MI D+ MPG G Sbjct: 4 VLLVDDEYMILQGLTMIIDWQALGFEVVQTARSGKEALAYLTQYPVDVMISDVTMPGMTG 63 Query: 61 LELIKELREDDPELHIIILSGYADFSYAKRAMSLGIDNYLLKPVDEDELHLYLTNLSAEL 120 L+LI+ + P+L +ILSGY +FSY ++AM L YLLKPVD+ EL + L Sbjct: 64 LDLIEAAKTYHPQLQTLILSGYQEFSYVQKAMELETKGYLLKPVDKAELQAKMKQFKDWL 123 Query: 121 AAR 123 A+ Sbjct: 124 DAQ 126 Score = 75.9 bits (185), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 38/101 (37%), Positives = 61/101 (60%), Gaps = 1/101 (0%) Query: 414 LIKRMLDLIHRHYPENLKLETLADVFTYSSAYLGKLFKSSTGLSFNSYLDNIRIGKAKE- 472 L+ +D I + Y + L L+ +AD + YLG+ FK+ T SF YL+++RI KA++ Sbjct: 382 LVSETIDCIRKEYHQELTLKAIADRLHVNGVYLGQCFKNETERSFTQYLNHVRIQKAQQL 441 Query: 473 LLDQGYKIHQAASEVGFSDVDYFREKFKKIEGLSPSDYRRK 513 LL I++ A E G++ YF + FKK+ GLSP ++R + Sbjct: 442 LLYTNQSINEIAYETGYNTNHYFIKMFKKLNGLSPKEFRDR 482 >SP0156 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 428 Score = 96.3 bits (238), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 51/124 (41%), Positives = 80/124 (64%) Query: 1 VLIVDDELAIREGLATLLDWESLGYVVVDTAANAIEAKHKYELHSPDLMIIDIRMPGRDG 60 VL+VDDE + EGL L+ ++ VV TA++A EA + + D++I D+ MP + G Sbjct: 4 VLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYVQENPVDVIISDVNMPDKTG 63 Query: 61 LELIKELREDDPELHIIILSGYADFSYAKRAMSLGIDNYLLKPVDEDELHLYLTNLSAEL 120 L++I+E++E P+ I+LSGY +F Y KRAM+L + +YL+KPVD+ EL L ++ +L Sbjct: 64 LDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDYLVKPVDKVELGNLLEKIAGQL 123 Query: 121 AARA 124 R Sbjct: 124 GERG 127 Score = 60.5 bits (145), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 42/140 (30%), Positives = 72/140 (51%), Gaps = 4/140 (2%) Query: 375 MDEQVEQIYKHTSLPKLQSHINVLLEQYAGGIKRDDMEVLIKRMLDLIHRHYPENLKLET 434 M + V+ I+ S +L S+I L + G + ++ V +L++I R Y + L L+ Sbjct: 287 MTDIVKTIHAIQSFDELVSYIKETLISFFGQYRMNENVV---SVLEVIGRDYQKELSLKD 343 Query: 435 LADVFTYSSAYLGKLFKSSTGLSFNSYLDNIRIGKAKE-LLDQGYKIHQAASEVGFSDVD 493 ++ + YLG+L K T +F L+ RI A++ LL I VG+S++ Sbjct: 344 ISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIEDICYAVGYSNLG 403 Query: 494 YFREKFKKIEGLSPSDYRRK 513 YF + F+K+ G SP YR++ Sbjct: 404 YFYKVFRKLCGKSPKAYRKQ 423 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.136 0.383 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 38,058,126 Number of extensions: 1618729 Number of successful extensions: 7047 Number of sequences better than 1.0e-05: 443 Number of HSP's gapped: 7744 Number of HSP's successfully gapped: 454 Length of query: 516 Length of database: 38,378,431 Length adjustment: 111 Effective length of query: 405 Effective length of database: 25,576,357 Effective search space: 10358424585 Effective search space used: 10358424585 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 118 (50.1 bits)