BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0060.0014.p (573 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH0090 [EH] COG0147 Anthranilate/para-aminobenzoate synthases co... 411 e-114 BS_pabB [EH] COG0147 Anthranilate/para-aminobenzoate synthases c... 380 e-105 NMA1247 [EH] COG0147 Anthranilate/para-aminobenzoate synthases c... 323 7e-88 NMB1021 [EH] COG0147 Anthranilate/para-aminobenzoate synthases c... 320 4e-87 all0328 [EH] COG0147 Anthranilate/para-aminobenzoate synthases c... 319 6e-87 >BH0090 [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I Length = 486 Score = 411 bits (1056), Expect = e-114, Method: Compositional matrix adjust. Identities = 225/475 (47%), Positives = 295/475 (62%), Gaps = 36/475 (7%) Query: 88 VVLESGKGGRYTYLGLHPVSVLQGKAGTAEIYSFPSDAAGTVEPLLETSRTGHPLEMLEL 147 V+LESG+GGRY+ +GL PV VL+GK T + T E + R G L+++ Sbjct: 45 VLLESGRGGRYSMVGLEPVMVLEGKKDTLIV---------TTENEV-VKRQGALLDLMRD 94 Query: 148 WMKDFTSPRVQVTELPPFIGGCIGFLSYDVVRSLEKLPVWAKDDPGFPDYLFMRLEELWT 207 + + + + PPF GG IGF SYD+VR +E+LP A+DD PD F+ ++++ Sbjct: 95 ALASYQAE--TLPGAPPFQGGAIGFFSYDLVREIERLPTIAQDDLNLPDLYFLIFDDVFI 152 Query: 208 YDHQEDMLYCTVHVPVPAAAQSSGPAELKDLYQKASRRAERMLEQWRQISAAPGNSXXXX 267 YDH++ + + VH G A +DL ++ R E +Q + S Sbjct: 153 YDHEKKVAWIFVH----------GDASEQDLSEQKLRHYEATWKQPVSLDEEVATSYLE- 201 Query: 268 XXXXXXXXXXVSGEWPGMTTAFPPEQFQQAVREVQEYIRQGDVFQVNLSLRQEAQLNSSP 327 GE +F E F +AV V+EYI GDVFQVNLS+R+ L ++P Sbjct: 202 ----------TEGE---KVHSFSEETFAKAVERVREYIAAGDVFQVNLSVREGRPLRTTP 248 Query: 328 EDVYEWLRKLNPSPYMGLLRSPRFALASASPELLVRLHGDKVSARPIAGTRRRGLTPAED 387 +YE LR++NPSPYM L +P F L S SPELL++ K+S RPIAGTR RG T ED Sbjct: 249 LSIYEALRQINPSPYMSYLHTPDFQLVSGSPELLIKKDSRKLSTRPIAGTRSRGATADED 308 Query: 388 AAMEAELRGSEKEIAEHIMLVDLERNDIGRVAAYGTVSVPELLTVERYSHVMHLVSQVEG 447 A+ L +EKE AEH+MLVDLERND+GRV+ YG+V V EL+ VE+YSHVMH+VS V G Sbjct: 309 EALVQTLLSNEKERAEHVMLVDLERNDLGRVSEYGSVEVNELMVVEKYSHVMHIVSNVRG 368 Query: 448 TVAPGKGAYDVMAALFPGGTITGAPKVRTMEIIEELEPVRRGPYTGSMGWIDYNGNMELN 507 + G A+D + A FPGGTITGAPKVRTMEIIEELEPVRRG YTGS+GWI YNG+MELN Sbjct: 369 VLKEGLDAFDAIRATFPGGTITGAPKVRTMEIIEELEPVRRGIYTGSIGWIGYNGDMELN 428 Query: 508 IIIRTLAVKDGIGYIQTGAGIVIDSDPYREYRECHNKAKAVVKAVLCSEYQQGSR 562 I+IRT+ KD + Y+Q GAG+VIDS+P EY+E KAKA+ +A S +Q R Sbjct: 429 IVIRTMLCKDEMAYVQAGAGVVIDSNPRYEYKESLKKAKALWRAYDQSIDEQKQR 483 >BS_pabB [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I Length = 453 Score = 380 bits (977), Expect = e-105, Method: Compositional matrix adjust. Identities = 0/472 (0%), Positives = 0/472 (0%), Gaps = 39/472 (8%) Query: 86 YSVVLESGKGGRYTYLGLHPVSVLQGKAGTAEIYSFPSDAAGTVEPLLETSRTGHPLEML 145 ++ Y+ + + + E RT + L Sbjct: 31 AMLLHSGYADHPYSRFDIVVAEPICTLTTFGKE-------TVVSESEK---RTTTTDDPL 80 Query: 146 ELWMKDFTSPRVQVTELPPFIGGCIGFLSYDVVRSLEKLPVWAKDDPGFPDYLFMRLEEL 205 ++ + ++ G L + + L + Sbjct: 81 QVLQQVLDRADIR--PTHNEDLPFQGGALGLFGYDLGRRFESLPEIAEQDIVLPDMAVGI 138 Query: 206 WTYDHQEDMLYCTVHVPVPAAAQSSGPAELKDLYQKASRRAERMLEQWRQISAAPGNSXX 265 + + D TV + + + + Q Sbjct: 139 YDWALIVDHQRHTVSLL--SHNDVNARRAWLESQQ-----------FS--PQEDFT---- 179 Query: 266 XXXXXXXXXXXXVSGEWPGMTTA-FPPEQFQQAVREVQEYIRQGDVFQVNLSLRQEAQLN 324 S F Q + + +A L Sbjct: 180 -------LTSDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHATYSGDEWQAFLQ 232 Query: 325 SSPEDVYEWLRKLNPSPYMGLLRSPRFALASASPELLVRLHGDKVSARPIAGTRRRGLTP 384 + + + L L SP + + E+ R + P + Sbjct: 233 LNQANRAPFSAFLRLEQGAILSLSPERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAVK 292 Query: 385 AEDAAMEAELRGSEKEIAEHIMLVDLERNDIGRVAAYGTVSVPELLTVERYSHVMHLVSQ 444 ++A + ++ + + + + P + + Sbjct: 293 LANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPFPAVHHLVSTITAQLPEQL 352 Query: 445 VEGTVAPGKGAYDVMAALFPGGTITGAPKVRTMEIIEELEPVRRGPYTGSMGWIDYNGNM 504 + + + ++ + + G+M + Sbjct: 353 HASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFCGNMDTSITIRTL 412 Query: 505 ELNIIIRTLAVKDGIGYIQTGAGIVIDSDPYREYRECHNKAKAVVKAVLCSE 556 Sbjct: 413 464 >NMA1247 [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I Length = 316 Score = 323 bits (827), Expect = 7e-88, Method: Compositional matrix adjust. Identities = 0/520 (0%), Positives = 0/520 (0%), Gaps = 49/520 (9%) Query: 42 ITAWQDWEQWAQEKWSLLPLIIRTPQDKGGLPASWMKAWELAS-PYSVVLESGKGG---- 96 + + L+ + + P + + S + Sbjct: 1 MLKEYFIRRALYLFPVLIFISFMSFSLIYIAPGDPAE---IMMTSPSGGYDEAAVEAFRI 57 Query: 97 RYTYLGLHPVSVLQGKAGTAEIYSFPSDAAGTVEPLLETSRTGHPLEMLELWMKDFTSPR 156 + + L A + + + S Sbjct: 58 AHGLDQPFYIQYLNWLKAAAVGDF----GYSYMS-----EQPVFETVLNAFKNTLTLSV- 107 Query: 157 VQVTELPPFIGGCIGFLSYDVVRSLE----KLPVWAKDDP-GFPDYLFMRLEELWTYDHQ 211 + FI G +S ++ + F + + Sbjct: 108 -LALAIALFISIPFGVVSALKHNTIVDDACRFGALLGVSMPNFWQAYLVIILFSVIIHWF 166 Query: 212 EDMLYCTVHVPVPAAAQSSGPAELKDLYQKASRRAERMLEQWRQISAAPGNSXXXXXXXX 271 + S + ++ + + S Sbjct: 167 PASGFGHGT------DISYMI----LPATVLGTGSAAVMMRMIRSSMLE----------- 205 Query: 272 XXXXXXVSGEWPGMTTAFPPEQFQQAVREVQEYIRQGDVFQVNLSLRQEAQLNSSPEDVY 331 EQ ++ + Sbjct: 206 ----VMGKEYIQTARGKGLSEQIVVFRHALKNALVPVITVVGLSIGFLLNGSVVVETIFG 261 Query: 332 EWLRKLNPSPYMGLLRSPRFALASASPELLVRLHGDKVSARPIAGTRRRGLTPAEDAAME 391 Sbjct: 262 321 Query: 392 AELRGSEKEIAEHIMLVDLERNDIGRVAAYGTVSVPELLTVERYSHVMHLVSQVEGTVAP 451 Sbjct: 322 381 Query: 452 GKGAYDVMAALFPGGTITGAPKVRTMEIIEELEPVRRGPYTGSMGWIDYNGNMELNIIIR 511 Sbjct: 382 441 Query: 512 TLAVKDGIGYIQTGAGIVIDSDPYREYRECHNKAKAVVKA 551 Sbjct: 442 481 >NMB1021 [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I Length = 491 Score = 320 bits (820), Expect = 4e-87, Method: Compositional matrix adjust. Identities = 195/520 (37%), Positives = 283/520 (54%), Gaps = 49/520 (9%) Query: 42 ITAWQDWEQWAQEKWSLLPLIIRTPQDKGGLPASWMKAWELAS-PYSVVLESGKGG---- 96 + + Q+++ A + ++ +PL+ D + ++K LA+ PY+ +LES GG Sbjct: 1 MISKQEYQAQAAQGYNRIPLVQELLADLDTPLSLYLK---LANRPYTYLLESVVGGERFG 57 Query: 97 RYTYLGLHPVSVLQGKAGTAEIYSFPSDAAGTVEPLLETSRTGHPLEMLELWMKDFTSPR 156 RY+++GL L+ ++Y VE G+PL +E + F +P Sbjct: 58 RYSFIGLPCSHYLKASGKHVDVYQ----NGEIVE-----QHDGNPLPFIEAFHNRFKTP- 107 Query: 157 VQVTELPPFIGGCIGFLSYDVVRSLE----KLPVWAKDDP-GFPDYLFMRLEELWTYDHQ 211 ++ LP F GG +G+ Y+ + + E +L K DP G PD L M +EL D+ Sbjct: 108 -EIPSLPRFTGGLVGYFGYETIYNFEHFAHRLKNTTKADPLGTPDILLMLSQELAVIDNL 166 Query: 212 EDMLYCTVHVPVPAAAQSSGPAELKDLYQKASRRAERMLEQWRQISAAPGNSXXXXXXXX 271 ++ V+ A S P D Y++A R E + Q RQ A P Sbjct: 167 SGKIHLVVY------ADPSQP----DGYERARERLEDIRTQLRQSCAIP----------- 205 Query: 272 XXXXXXVSGEWPGMTTAFPPEQFQQAVREVQEYIRQGDVFQVNLSLRQEAQLNSSPEDVY 331 + + + F E F+ V ++++YI GD QV S R + SP +Y Sbjct: 206 ----LSLGSKHTEAVSEFGEEPFKACVNKIKDYIFAGDCMQVVPSQRMSMEFTDSPLALY 261 Query: 332 EWLRKLNPSPYMGLLRSPRFALASASPELLVRLHGDKVSARPIAGTRRRGLTPAEDAAME 391 LR LNPSPY+ F + +SPE+LVR + V RPIAGTR RG TPAED A E Sbjct: 262 RALRTLNPSPYLFYYDFGDFHIVGSSPEILVRRERNDVIVRPIAGTRLRGKTPAEDLANE 321 Query: 392 AELRGSEKEIAEHIMLVDLERNDIGRVAAYGTVSVPELLTVERYSHVMHLVSQVEGTVAP 451 +L KEIAEH+ML+DL RND+GR++ G V V + + +E+YSHVMH+VS VEG + Sbjct: 322 QDLLSDAKEIAEHVMLIDLGRNDVGRISKTGEVKVTDKMVIEKYSHVMHIVSNVEGRLKD 381 Query: 452 GKGAYDVMAALFPGGTITGAPKVRTMEIIEELEPVRRGPYTGSMGWIDYNGNMELNIIIR 511 G D++AA FP GT++GAPKVR MEIIEE+EP +RG Y G++G +N +M+L I IR Sbjct: 382 GMTNMDILAATFPAGTLSGAPKVRAMEIIEEVEPSKRGIYGGAVGVWGFNNDMDLAIAIR 441 Query: 512 TLAVKDGIGYIQTGAGIVIDSDPYREYRECHNKAKAVVKA 551 T VK+ Y+Q+GAG+V DSDP E++E NKA+AV+ A Sbjct: 442 TAVVKNNTLYVQSGAGVVADSDPASEWQETQNKARAVIHA 481 >all0328 [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I Length = 504 Score = 319 bits (818), Expect = 6e-87, Method: Compositional matrix adjust. Identities = 189/491 (38%), Positives = 278/491 (56%), Gaps = 32/491 (6%) Query: 74 ASWMKAWELASPYSVVLESGKGG----RYTYLGLHPVSVLQGKAGTAEIYSFPSDAAGTV 129 ++W K PYS +LES +GG RY+ LG P+ VL+ + T + ++ G+ Sbjct: 34 SAWYKVCA-GEPYSFLLESVEGGEKIGRYSLLGCDPLWVLEARGET----TTQTNRDGS- 87 Query: 130 EPLLETSRTGHPLEMLELWMKDFTSPRVQVTELPPFIGGCIGFLSYDVVRSLE-KLPVWA 188 + TG P L + + V++ +LPP IGG GF Y+++R +E ++PV Sbjct: 88 ----QVVFTGDPFTALADCLAPYKP--VKLPQLPPGIGGLFGFWGYELIRWIEPRVPVHP 141 Query: 189 KDDPGFPDYLFMRLEELWTYDHQEDMLYCTVHVPVPAAAQSSGPAELKDLYQKASRRAER 248 +D+ PD L+M+++ L +D + ++ + A +LK YQ+A R + Sbjct: 142 QDERNIPDGLWMQVDHLLIFDQVKRKIWAIAY-----ADLRDPNVDLKAAYQQACDRVTQ 196 Query: 249 MLEQWRQISAAPGNSXXXXXXXXXXXXXXVSGEWPGMTTAFPPEQFQQAVREVQEYIRQG 308 M+ + + +P + GE T+ F +F +V++ +EYI+ G Sbjct: 197 MVSKL-SLPLSPQKTILEWTPPGSQKV----GEIQEYTSNFTRPEFCASVQKAKEYIKAG 251 Query: 309 DVFQVNLSLRQEAQLNSSPEDVYEWLRKLNPSPYMGLLRSPRFALASASPELLVRLHGDK 368 D+FQV +S R Q P +Y LR++NPSPYM + + +SPE++V+ D Sbjct: 252 DIFQVVISQRLSTQYTGDPFSLYRSLRQINPSPYMAYFNFQDWQIIGSSPEVMVKAELDA 311 Query: 369 -----VSARPIAGTRRRGLTPAEDAAMEAELRGSEKEIAEHIMLVDLERNDIGRVAAYGT 423 + RPIAGTR RG T EDA + A+L KEIAEH+MLVDL RND+GRV A GT Sbjct: 312 DGEAIATVRPIAGTRPRGKTTKEDAELAADLLQDPKEIAEHVMLVDLGRNDLGRVCASGT 371 Query: 424 VSVPELLTVERYSHVMHLVSQVEGTVAPGKGAYDVMAALFPGGTITGAPKVRTMEIIEEL 483 V V EL+ VERYSHVMH+VS V G +A K A+D++ A FP GT++GAPK+R MEII EL Sbjct: 372 VKVDELMVVERYSHVMHIVSNVVGKLAANKNAWDLLKACFPAGTVSGAPKIRAMEIINEL 431 Query: 484 EPVRRGPYTGSMGWIDYNGNMELNIIIRTLAVKDGIGYIQTGAGIVIDSDPYREYRECHN 543 EP RRG Y+G G+ D+ G + I IRT+ V+D +Q GAG+V DS+P +EY E N Sbjct: 432 EPSRRGVYSGVYGYYDFEGQLNSAIAIRTMVVRDQTVTVQAGAGLVADSEPEKEYEETLN 491 Query: 544 KAKAVVKAVLC 554 KA+ ++ A+ C Sbjct: 492 KARGLLLAIRC 502 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.135 0.407 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 43,800,203 Number of extensions: 1888086 Number of successful extensions: 4420 Number of sequences better than 1.0e-05: 104 Number of HSP's gapped: 4268 Number of HSP's successfully gapped: 110 Length of query: 573 Length of database: 38,378,431 Length adjustment: 112 Effective length of query: 461 Effective length of database: 25,461,023 Effective search space: 11737531603 Effective search space used: 11737531603 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 118 (50.1 bits)