BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0060.0006.p (684 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_ftsH [O] COG0465 ATP-dependent Zn proteases 737 0.0 CAC3202 [O] COG0465 ATP-dependent Zn proteases 601 e-171 alr1261 [O] COG0465 ATP-dependent Zn proteases 576 e-164 STM0580 [K] COG1309 Transcriptional regulator 544 e-154 ML0204 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases 542 e-154 >BS_ftsH [O] COG0465 ATP-dependent Zn proteases Length = 637 Score = 737 bits (1903), Expect = 0.0, Method: Compositional matrix adjust. Identities = 377/617 (61%), Positives = 449/617 (72%), Gaps = 13/617 (2%) Query: 1 MNRFIRNSGFYLILFLVVVGIVQFVSNGNESADFPRYDELRQEIKNNNVKSMTIQFEGNA 60 MNR RN+ FYL++ LVV+G+V + N + Y + + + V S+++Q Sbjct: 1 MNRVFRNTIFYLLILLVVIGVVSYFQTSNPKTENMSYSTFIKNLDDGKVDSVSVQPVRGV 60 Query: 61 FAVTGEYKQQPAEAKSKNFSTFVPPTDRALDELIAASDDNGIELTQKKMEG---DSIWLT 117 + V G+ K K + F T VP + D++ N ++ T K+E S W+T Sbjct: 61 YEVKGQLKNYD---KDQYFLTHVP-EGKGADQIF-----NALKKTDVKVEPAQETSGWVT 111 Query: 118 FLSSXXXXXXXXXXXXXXXNQAQGGGGKVMNFGKSKARLYNEEKKKISFEDVAGADEEKQ 177 FL++ NQAQGGG +VMNFGKSKA+LY EEKK++ F+DVAGADEEKQ Sbjct: 112 FLTTIIPFVIIFILFFFLLNQAQGGGSRVMNFGKSKAKLYTEEKKRVKFKDVAGADEEKQ 171 Query: 178 ELVEVVEFLKDPRKFAAVGARIPKGVLLVGPPGTGKTLLARAVAGEAGVPFFSISGSDFV 237 ELVEVVEFLKDPRKFA +GARIPKGVLLVGPPGTGKTLLA+A AGEAGVPFFSISGSDFV Sbjct: 172 ELVEVVEFLKDPRKFAELGARIPKGVLLVGPPGTGKTLLAKACAGEAGVPFFSISGSDFV 231 Query: 238 EMFVGVGASRVRDLFENAKKNAPCIIFIDEIDAVXXXXXXXXXXXHDEREQTLNQLLVEM 297 EMFVGVGASRVRDLFENAKKNAPC+IFIDEIDAV HDEREQTLNQLLVEM Sbjct: 232 EMFVGVGASRVRDLFENAKKNAPCLIFIDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEM 291 Query: 298 DGFGGNEGIIIVAATNRADILDPALLRPGRFDRQITVDRPDVKGREAVLKVHSRNKPLTK 357 DGF NEGIII+AATNRADILDPALLRPGRFDRQITVDRPDV GREAVLKVH+RNKPL + Sbjct: 292 DGFSANEGIIIIAATNRADILDPALLRPGRFDRQITVDRPDVIGREAVLKVHARNKPLDE 351 Query: 358 DVRLDVIAKRTTGFTGADXXXXXXXXXXXXXXXXXKDISMTEVDEAIDRVIVGTEKRSRV 417 V L IA RT GF+GAD K I ++DEA DRVI G K+SRV Sbjct: 352 TVNLKSIAMRTPGFSGADLENLLNEAALVAARQNKKKIDARDIDEATDRVIAGPAKKSRV 411 Query: 418 ISEREKRIVAYHEAGHTIVGYFLEHADMVHKVTIIPRGRAGGYVIMLPKEDRMLVTKQEL 477 IS++E+ IVAYHE GHT++G L+ ADMVHKVTI+PRG+AGGY +MLP+EDR TK EL Sbjct: 412 ISKKERNIVAYHEGGHTVIGLVLDEADMVHKVTIVPRGQAGGYAVMLPREDRYFQTKPEL 471 Query: 478 LDKVTGLLGGRVAEELFIGEIGTGAYSDFQQATRIVRSMIMEYGMSDKLGPMQFGTSQ-G 536 LDK+ GLLGGRVAEE+ GE+ TGA++DFQ+AT I R M+ E+GMS+KLGP+QFG SQ G Sbjct: 472 LDKIVGLLGGRVAEEIIFGEVSTGAHNDFQRATNIARRMVTEFGMSEKLGPLQFGQSQGG 531 Query: 537 QVFLGRDIGHEQNYSDSIAYEIDQEMQNFIRSSYERCKELLTKYSKEMHLIANTLLEKET 596 QVFLGRD +EQNYSD IAYEIDQE+Q I+ YER K++LT+ ++ LIA TLL+ ET Sbjct: 532 QVFLGRDFNNEQNYSDQIAYEIDQEIQRIIKECYERAKQILTENRDKLELIAQTLLKVET 591 Query: 597 LELDQIKELIEQGYLTE 613 L+ +QIK LI+ G L E Sbjct: 592 LDAEQIKHLIDHGTLPE 608 >CAC3202 [O] COG0465 ATP-dependent Zn proteases Length = 602 Score = 601 bits (1550), Expect = e-171, Method: Compositional matrix adjust. Identities = 313/609 (51%), Positives = 414/609 (67%), Gaps = 14/609 (2%) Query: 5 IRNSGFYLILFLVVVGIVQFVSNGNESADFPRYDELRQEIKNNNVKSMTIQFEGNAFAVT 64 I ++ ++++FLVV+ + + G ++ + +D+ +++ NN+KS + + + V Sbjct: 4 ISSATVWIVVFLVVIFTILMLVQGGKATNTVSFDQFQKQYMGNNIKSF--EMKDDKMTVD 61 Query: 65 GEYKQQPAEAKSKNFSTFVPPTDRALDELIAASDDNG-IELTQKKMEGDSIWLTFLSSXX 123 G+YK +F T VP L++ +A NG I + +W++++ + Sbjct: 62 GKYKD------GSSFETIVPL--ERLNQFLADHPTNGEIGESYAAPANIPVWISWMPTII 113 Query: 124 XXXXXXXXXXXXXNQAQGGGGK-VMNFGKSKARLYNEE--KKKISFEDVAGADEEKQELV 180 Q QGG GK VM FGKS+A++ + + K+K++F+DVAGADEEK EL Sbjct: 114 MILAMVVILVLFMQQTQGGTGKGVMGFGKSRAKMSSPDDLKQKVTFKDVAGADEEKGELE 173 Query: 181 EVVEFLKDPRKFAAVGARIPKGVLLVGPPGTGKTLLARAVAGEAGVPFFSISGSDFVEMF 240 E+V+FLK P+++ +GARIPKGVLLVGPPGTGKTLLA+AV+GEAGVPFFSISGSDFVEMF Sbjct: 174 EIVDFLKQPKRYIEMGARIPKGVLLVGPPGTGKTLLAKAVSGEAGVPFFSISGSDFVEMF 233 Query: 241 VGVGASRVRDLFENAKKNAPCIIFIDEIDAVXXXXXXXXXXXHDEREQTLNQLLVEMDGF 300 VGVGASRVRDLFE AKKN+PCIIFIDEIDAV HDEREQTLNQLLVEMDGF Sbjct: 234 VGVGASRVRDLFEQAKKNSPCIIFIDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGF 293 Query: 301 GGNEGIIIVAATNRADILDPALLRPGRFDRQITVDRPDVKGREAVLKVHSRNKPLTKDVR 360 G NEGIII+AATNR DILD ALLRPGRFDRQI V PDVKGRE +LKVHS+NK L +R Sbjct: 294 GVNEGIIILAATNRPDILDHALLRPGRFDRQILVGAPDVKGREEILKVHSKNKNLDDSIR 353 Query: 361 LDVIAKRTTGFTGADXXXXXXXXXXXXXXXXXKDISMTEVDEAIDRVIVGTEKRSRVISE 420 LDV+AKRT GFTGAD I M E++EA RVI G EK+SRVISE Sbjct: 354 LDVLAKRTPGFTGADLENLMNEAALLAVRNKKPIIGMEELEEATTRVIAGPEKKSRVISE 413 Query: 421 REKRIVAYHEAGHTIVGYFLEHADMVHKVTIIPRGRAGGYVIMLPKEDRMLVTKQELLDK 480 +++I AYHEAGH ++ L ++D VH+++I+PRG AGGY + LP++D ++K +L D+ Sbjct: 414 EDRKITAYHEAGHAVLMELLPYSDPVHQISIVPRGMAGGYTMHLPEKDSSYMSKNKLKDE 473 Query: 481 VTGLLGGRVAEELFIGEIGTGAYSDFQQATRIVRSMIMEYGMSDKLGPMQFGTSQGQVFL 540 + GLLGGR+AE+L IG+I TGA +D +AT I R M+MEYGMSDKLG + FG Q +VFL Sbjct: 474 MVGLLGGRIAEKLVIGDISTGAKNDIDRATSIARKMVMEYGMSDKLGTITFGKDQDEVFL 533 Query: 541 GRDIGHEQNYSDSIAYEIDQEMQNFIRSSYERCKELLTKYSKEMHLIANTLLEKETLELD 600 GRD+G +N+S+ IA +ID E++ I +Y + + LL ++ +A LLEKE LE D Sbjct: 534 GRDLGTSRNFSEEIAAKIDNEVKELIDEAYTKAENLLKDNMSKLDAVAKALLEKEKLEAD 593 Query: 601 QIKELIEQG 609 + KE+ E Sbjct: 594 EFKEIFENA 602 >alr1261 [O] COG0465 ATP-dependent Zn proteases Length = 359 Score = 576 bits (1484), Expect = e-164, Method: Compositional matrix adjust. Identities = 0/613 (0%), Positives = 0/613 (0%), Gaps = 18/613 (2%) Query: 1 MNRFIRNSGFYLILFLVVVGI-VQFVSNGNESADFPRYDELRQEIKNNNVKSMTIQFEGN 59 M + + + S Y E + Sbjct: 1 MQAATVVINRRALRHNLQRLRELAPASKMVAVVKANAYGHGLLETARTLPDADAFGVARL 60 Query: 60 AFAVTGEYKQQPAEAKSKNFSTFVPPTDRALDELIAASDDNGIELTQKKMEGDSIWLTFL 119 A+ + + + + Sbjct: 61 EEALRLRAG------GITKPVLLLEGF-----FDARDLPTISAQHFHTAVHNEEQLAALE 109 Query: 120 SSXXXXXXXXXXXXXXXNQAQGG-GGKVMNFGKSKARLYNEEKKKISFEDVAGADEEKQE 178 + G + F + N + A ADE K Sbjct: 110 EASLDEPVTVWMKLDTGMHRLGVRPEQAEAFYHRLTQCKNVRQPVNIVSHFARADEPKCG 169 Query: 179 LVEVVEFLKDPRKFAAVGARIPKGVLLVGPPGTGKTLLARAVAGEAGVPFFSISGSDFVE 238 E + + G R + R GV + Sbjct: 170 ATEKQLAIFNTFCEGKPGQRSIAASGGILLWPQSHFDWVRPGIILYGVSPLEDRSTGADF 229 Query: 239 MFVGVGASRVRDLFENAKKNAPCIIFIDEIDAVXXXXXXXXXXXHDEREQTLNQLLVEMD 298 V + + K + + + + + + Sbjct: 230 GCQPVMSLTSSLIAVREHKAGEPVGYGGTWVSERDTRLGVVAMGYGDGYPRAAPSGTPVL 289 Query: 299 GFGGNEGIIIVAATNRADILDPALLRPGRFDRQITVDRPDVKGREAVLKVHSRNKPLTKD 358 G I+ A + + + D I R A + S + +T+ Sbjct: 290 VNGREVPIVGRVAMDMICVDLGPQAQDKAGDPVILWGEGLPVERIAEMTKVSAYELITRL 349 Query: 359 VRLDVIAKRTTGFTGADXXXXXXXXXXXXXXXXXKDISMTEVDEAIDRVIVGTEKRSRVI 418 Sbjct: 350 409 Query: 419 SEREKRIVAYHEAGHTIVGYFLEHADMVHKVTIIPRGRAGGYVIMLPKEDRM---LVTKQ 475 Sbjct: 410 469 Query: 476 ELLDKVTGLLGGRVAEELFIG--EIGTGAYSDFQQATRIVRSMIMEYGMSDKLGPMQFGT 533 Sbjct: 470 529 Query: 534 SQGQVFLGRDIGHEQNYSDSIAYEIDQEMQNFIRSSYERCKELLTKYSKEMHLIANTLLE 593 Sbjct: 530 589 Query: 594 KETLELDQIKELI 606 Sbjct: 590 602 >STM0580 [K] COG1309 Transcriptional regulator Length = 193 Score = 544 bits (1401), Expect = e-154, Method: Compositional matrix adjust. Identities = 0/521 (0%), Positives = 0/521 (0%), Gaps = 2/521 (0%) Query: 92 ELIAASDDNGIELTQKKMEGDSIWLTFLSSXXXXXXXXXXXXXXXNQAQGGGGKVMNFGK 151 + L L + +M F Sbjct: 85 TRFIWNSYISWGLNHPARHRAIRQLAVSEKLTKETEQRADDMFPELRDLCHRSVLMVFMS 144 Query: 152 SKARLYNEE-KKKISFEDVAGADEEKQELVEVVEFLKDPRKFAAVGARIPKGVLLVGPPG 210 + R + + Sbjct: 145 DEYRAFGDGL 204 Query: 211 TGKTLLARAVAGEAGVPFFSISGSDFVEMFVGVGASRVRDLFENAKKNAPCIIFIDEIDA 270 Sbjct: 205 264 Query: 271 VXXXXXXXXXXXHDEREQTLNQLLVEMDGFGGNEGIIIVAATNRADILDPALLRPGRFDR 330 Sbjct: 265 324 Query: 331 QITVDRPDVKGREAVLKVHSRNKPLTKDVRLDVIAKRTTGFTGADXXXXXXXXXXXXXXX 390 Sbjct: 325 384 Query: 391 XXKDISMTEVDEAIDRVIVGTEKRSRVISEREKRIVAYHEAGHTIVGYFLEHADMVHKVT 450 Sbjct: 385 444 Query: 451 IIPRG-RAGGYVIMLPKEDRMLVTKQELLDKVTGLLGGRVAEELFIGEIGTGAYSDFQQA 509 Sbjct: 445 504 Query: 510 TRIVRSMIMEYGMSDKLGPMQFGTSQGQVFLGRDIGHEQNYSDSIAYEIDQEMQNFIRSS 569 Sbjct: 505 564 Query: 570 YERCKELLTKYSKEMHLIANTLLEKETLELDQIKELIEQGY 610 Sbjct: 565 605 >ML0204 [MG] COG0451 Nucleoside-diphosphate-sugar epimerases Length = 695 Score = 542 bits (1397), Expect = e-154, Method: Compositional matrix adjust. Identities = 305/660 (46%), Positives = 414/660 (62%), Gaps = 29/660 (4%) Query: 4 FIRNSGFYLILFLVVVGIVQFVSNGNESA-DFPRYDELRQEIKNNNVKSMTIQFEGNAFA 62 F++N ++IL +VVV F + N+S+ D Y +L ++ N ++++T+Q + Sbjct: 12 FVKNILMWVILAIVVVVGFNFFFSSNQSSVDKISYSQLMTKLDGNKIENVTMQPSDSLIT 71 Query: 63 VTGEYKQQPAEAKS--------------KNFSTFVPPTDRALDELIAASDDNGIELTQKK 108 VTGEYK+ P + K KNF ++ PTD + ++ A+ N ++L+ + Sbjct: 72 VTGEYKE-PVKVKGTNNFPLLGNSSSEVKNFQAYIIPTDSVVKDIQNAAKSNDVKLSVVQ 130 Query: 109 MEGDSIWLTFLSSXXXXXXX----XXXXXXXXNQAQGGGGKVMNFGKSKARLYNEEKKKI 164 +W+ LS + GGGG M+FGKS+A+ + + K+ Sbjct: 131 ASSSGMWVQILSYIIPMLLFVGIFWLMMGGMGARGGGGGGNPMSFGKSRAKQQDGKTSKV 190 Query: 165 SFEDVAGADEEKQELVEVVEFLKDPRKFAAVGARIPKGVLLVGPPGTGKTLLARAVAGEA 224 F DVAG++EEKQELVEVV+FLK+P+K+ +GARIP GVLL GPPGTGKTLLA+AVAGEA Sbjct: 191 RFADVAGSEEEKQELVEVVDFLKNPKKYHDLGARIPAGVLLEGPPGTGKTLLAKAVAGEA 250 Query: 225 GVPFFSISGSDFVEMFVGVGASRVRDLFENAKKNAPCIIFIDEIDAVXXXXXXXXXXXHD 284 GVPF+SISGSDFVEMFVGVGASRVRDLFENAKK AP IIFIDEIDAV +D Sbjct: 251 GVPFYSISGSDFVEMFVGVGASRVRDLFENAKKTAPSIIFIDEIDAVGRQRGAGLGGGND 310 Query: 285 EREQTLNQLLVEMDGF--GGNEGIIIVAATNRADILDPALLRPGRFDRQITVDRPDVKGR 342 EREQTLNQLLVEMDGF GN +I++AATNR+D+LDPALLRPGRFDR++ V PDVKGR Sbjct: 311 EREQTLNQLLVEMDGFQDDGN-SVIVIAATNRSDVLDPALLRPGRFDRKVLVGAPDVKGR 369 Query: 343 EAVLKVHSRNKPLTKDVRLDVIAKRTTGFTGADXXXXXXXXXXXXXXXXXKDISMTEVDE 402 EAVLKVH++NKPL DV L +A +T G+ GAD K+I+ ++DE Sbjct: 370 EAVLKVHAKNKPLASDVDLHNVATQTPGYVGADLENVLNEAALVAARQNKKEINAADIDE 429 Query: 403 AIDRVIVGTEKRSRVISEREKRIVAYHEAGHTIVGYFLEHADMVHKVTIIPRGRAGGYVI 462 +DR + G K+ R+ S RE+ IVAYHEAGH IVG LE+ V KVT++PRGR GGY++ Sbjct: 430 GMDRAMAGPAKKDRIQSMREREIVAYHEAGHAIVGLVLENGSTVRKVTVVPRGRIGGYML 489 Query: 463 MLPKEDRMLVTKQELLDKVTGLLGGRVAEELFIGEIGTGAYSDFQQATRIVRSMIMEYGM 522 LP E+ M T L D++ L+GGR+ EE+ G GA +D ++AT I RSM+ EYGM Sbjct: 490 ALPDEEIMQPTNFHLQDQLASLMGGRLGEEIVFGVATPGASNDIEKATHIARSMVTEYGM 549 Query: 523 SDKLGPMQFGTSQGQVFLGRDIGHEQNYSDSIAYEIDQEMQNFIRSSYERCKELLTKYSK 582 S KLG + + QVF+GRD G + YS++ A ID E++ + +Y+R KE + + + Sbjct: 550 SKKLGMVSY-EGDHQVFIGRDYGQTKTYSEATAVMIDDEVRRILGEAYDRAKEAIETHRE 608 Query: 583 EMHLIANTLLEKETLELDQIKELIEQGYLTEDGKPEDAAGVTHEEGEPVIDSIGDVRVRI 642 + IA LL+ ETL+ QI L + G + P++AA E + +S+ D + Sbjct: 609 QHKAIAEALLKYETLDAKQIMSLFKTGKM-----PDEAAAAEVPEPKTFEESLKDANANV 663 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.317 0.137 0.382 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 47,082,993 Number of extensions: 2038930 Number of successful extensions: 8714 Number of sequences better than 1.0e-05: 122 Number of HSP's gapped: 8438 Number of HSP's successfully gapped: 152 Length of query: 684 Length of database: 38,378,431 Length adjustment: 113 Effective length of query: 571 Effective length of database: 25,345,689 Effective search space: 14472388419 Effective search space used: 14472388419 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 119 (50.4 bits)