BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0060.0004.p (484 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value STM0579 [S] COG2315 Uncharacterized protein conserved in bacteria 134 3e-31 TM0579 [D] COG0037 Predicted ATPase of the PP-loop superfamily i... 134 3e-31 CPn0997 [D] COG0037 Predicted ATPase of the PP-loop superfamily ... 110 5e-24 FN1977 [D] COG0037 Predicted ATPase of the PP-loop superfamily i... 109 9e-24 aq_1887 [D] COG0037 Predicted ATPase of the PP-loop superfamily ... 105 2e-22 >STM0579 [S] COG2315 Uncharacterized protein conserved in bacteria Length = 122 Score = 134 bits (338), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 0/432 (0%), Positives = 0/432 (0%), Gaps = 57/432 (13%) Query: 27 IVVAVSGGPDSVALLHILHEISLNRMPLTLICAHVNHGFRPESVEEAEAVRAMAGRLGLP 86 + + + Sbjct: 8 AWAKRFALELPFTEHCWPFGPQ-YDVFKVGGKIFMLFTEHHCRPVVNLKSDPQKSLVNQQ 66 Query: 87 FELAEFDIPSLVKESGLGPEGAAREKRYQFLIDTAHRYAARSVALAHHADDQAETVXXXX 146 Sbjct: 67 126 Query: 147 XXXXXXXXXXXXXWKRTEKKVELIRPFLRINKTALVSLCRQEGLPYAEDASNLMTEYRRN 206 Sbjct: 127 ---- 182 Query: 207 AVRLNLIPALEAYNPKVRQSLLQLSEIVQAEDEYMEAAAQKYF--NELVLADAGKCTMQR 264 Sbjct: 183 242 Query: 265 ALFTAIPSALQRRLIKLILNYLSADSSSLDFPKIEAVRRGTLQDYPT-VWSLNMGGGLIC 323 Sbjct: 243 ----------------- 285 Query: 324 MRQYDTIVFSSKPPQQESSYTYRLSLPHPRVEIKEIGKVLTMSVLERENFTV-LGEDSGK 382 Sbjct: 286 ------------------ 327 Query: 383 MLAWFDSGELVLPLTIRSRLPGDTIRVMGLNGSXXXXXXXXXXXXPSSERAAIPLVCDDL 442 Sbjct: 328 ------------- 374 Query: 443 GNIVWIPGVRRS 454 Sbjct: 375 386 >TM0579 [D] COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Length = 414 Score = 134 bits (338), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 115/432 (26%), Positives = 186/432 (43%), Gaps = 57/432 (13%) Query: 27 IVVAVSGGPDSVALLHILHEISLNRMPLTLICAHVNHGFRPESVEEAEAVRAMAGRLGLP 86 ++VAVSGG DS+ LL++L + S + + + AH++H R S + E V + + +P Sbjct: 8 VLVAVSGGIDSMTLLYVLRKFS-PLLKIKITAAHLDHRIRESSRRDREFVERICRQWNIP 66 Query: 87 FELAEFDIPSLVKESGLGPEGAAREKRYQFLIDTAHRYAARSVALAHHADDQAETVXXXX 146 E +E D+PSL K+SG E ARE RY FL TA + A +ALAHH +D ETV Sbjct: 67 VETSEVDVPSLWKDSGKTLEEIAREVRYDFLKRTAKKVGASKIALAHHKNDLLETVVHRL 126 Query: 147 XXXXXXXXXXXXXWKRTEKKVELIRPFLRINKTALVSLCRQEGLPYAEDASNLMTEYRRN 206 KR E IRPFL ++ + R+ +PY D +N +Y RN Sbjct: 127 IRGTGPLGLACISPKRE----EFIRPFLVFKRSEIEEYARKNNVPYVVDETNYNVKYTRN 182 Query: 207 AVRLNLIPALEAYNPKVRQSLLQLSEIVQAEDEYMEAAAQKYF--NELVLADAGKCTMQR 264 +R ++P ++ NP V ++ +L + ++E Q + N D Sbjct: 183 FIRHRIVPLMKELNPTVEDAVYRLVSVTHLLRNFVERTVQDFVERNVYFYKDYAVFVEPE 242 Query: 265 ALFTAIPSALQRRLIKLILNYLSADSSSLDFPKIEAVRRGTLQDYPT-VWSLNMGGGLIC 323 LF + + R ++K + + P+ E + GTL+ +WS G+ Sbjct: 243 DLFLFL--EVTRWVLKEMYGRV---------PEYEKL-IGTLKSKRVELWS-----GIFV 285 Query: 324 MRQYDTIVFSSKPPQQESSYTYRLSLPHPRVEIKEIGKVLTMSVLERENFTV-LGEDSGK 382 R + + +++ RVE+K +LE E F + + + Sbjct: 286 ERSFGYVAVGKTVFKKKY-----------RVEVKG-------DMLEMEGFKIRVVNNRND 327 Query: 383 MLAWFDSGELVLPLTIRSRLPGDTIRVMGLNGSXXXXXXXXXXXXPSSERAAIPLVCDDL 442 M W +R+R GD I V G P+ R +PL+ D+ Sbjct: 328 MKFW-----------VRNRKEGDRIIVNG--RERKLKDVFIEKKVPTFYRDRVPLLVDEE 374 Query: 443 GNIVWIPGVRRS 454 ++W+PG+ RS Sbjct: 375 DRVLWVPGIARS 386 >CPn0997 [D] COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Length = 319 Score = 110 bits (275), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 81/281 (28%), Positives = 130/281 (46%), Gaps = 24/281 (8%) Query: 28 VVAVSGGPDSVALLHILHEISLNRMPLTLICAHVNHGFRPESVEEAEAVRAMAGRLGLPF 87 ++A+SGG DS+ L ++L E ++ H++HG+R S +EA+ + + R G+PF Sbjct: 28 LLALSGGSDSLFLFYLLKE-----RGVSFTAVHIDHGWRSTSAQEAKELEELCAREGVPF 82 Query: 88 ELAEFDIPSLVKESGLGPEGAAREKRYQFLIDTAHRYAARSVALAHHADDQAETVXXXXX 147 L + ++ E AR+KRY FL ++ + A + LAHHA+DQAETV Sbjct: 83 VLYTL---TAEEQGDKDLENQARKKRYAFLYESYRQLDAGGIFLAHHANDQAETVLKRLL 139 Query: 148 XXXXXXXXXXXXWKRTEKKVELIRPFLRINKTALVSLCRQEGLPYAEDASNLMTEYRRNA 207 + + V L+RP L I K++L G+ Y +D SN Y R Sbjct: 140 ESAHLTNLKAMAERSYVEDVLLLRPLLHIPKSSLKEALDARGISYLQDPSNEDERYLRAR 199 Query: 208 VRLNLIPAL-EAYNPKVRQSLLQLSEIVQAEDEYMEAAAQKYFNELVLADAG------KC 260 +R L P L E + + LL L E EY+E AQ +F+ D+ C Sbjct: 200 MRKKLFPWLEEVFGKNITFPLLTLGEESAELSEYLEKQAQPFFSAATHQDSQGELPCPDC 259 Query: 261 TMQRA---------LFTAIPSALQRRLIKLILNYLSADSSS 292 +Q+A F A+ R ++++ ++LS S + Sbjct: 260 LIQQAFLCKWVMKKFFNNAGIAVSRHFLQMVYDHLSRSSCA 300 >FN1977 [D] COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Length = 448 Score = 109 bits (273), Expect = 9e-24, Method: Compositional matrix adjust. Identities = 68/229 (29%), Positives = 102/229 (44%), Gaps = 7/229 (3%) Query: 6 ELVESVLESAAEHGLWSPHDTIVVAVSGGPDSVALLHILHEISLNRMPLTLICAHVNHGF 65 EL +L+ ++ L +DTIVV SGGPDSV L+ +L ++ + H+NH Sbjct: 2 ELFREILKLNKKYNLIENNDTIVVGFSGGPDSVFLVEMLKKLQY-FFNFKIYLVHINHLL 60 Query: 66 RPESVEEAEAVR-AMAGRLGLPFELAEFDIPSLVKESGLGPEGAAREKRYQFLIDTAHRY 124 R E + E A + L + + + KE G E RE+RY+F + + Sbjct: 61 RGEDADSDENFSFEYAKKNNLEIFIKRIPVKEIAKEVGKTLEEVGREERYKFFSEIYEKV 120 Query: 125 AARSVALAHHADDQAETVXXXXXXXXXXXXXXXXXWKRTEKKVELIRPFLRINKTALVSL 184 A +A AH+ DDQ ET K +IRP I K ++ Sbjct: 121 GANKIATAHNKDDQIETFLFRLIRGTSLQGLEGIKIKNNN----IIRPISEIYKKDILEY 176 Query: 185 CRQEGLPYAEDASNLMTEYRRNAVRLNLIPALEA-YNPKVRQSLLQLSE 232 + + Y D +N E+ RN++RLNLIP +E YN K + + L E Sbjct: 177 LNKNEIQYKIDKTNFENEFTRNSIRLNLIPFIEERYNIKFKDKIFSLIE 225 >aq_1887 [D] COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Length = 784 Score = 105 bits (261), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 13/329 (3%), Positives = 56/329 (17%), Gaps = 23/329 (6%) Query: 7 LVESVLESAAEHGLWSPHDTIVVAVSGGPDSVALLHILHEISLNRMPLTLIC-AHVNHGF 65 + + + + A + + G S + + + + A ++ Sbjct: 7 TLLATMIATALYSQQGLAADLASQCMLGVPSYDRPLVQGDTN-DLPVTINADHAKGDYPD 65 Query: 66 RPESVEEAEAVRAMAGRLGLPFELAEFDIPSLVKESGLGPEGAAREKRYQFLIDTAHRYA 125 + ++ + +L + + P + +I + Sbjct: 66 DAVFTGSVDIMQGNSRLQADEVQLHQKEAPGQPEPVRTVDALGNVHYDDNQVILKGPKGW 125 Query: 126 ARSVALAHHADDQAETVXXXXXXXXXXXXXXXXXWKRTEKKVELIR-PFLRINKTALVSL 184 A + + + + ++ + Sbjct: 126 ANLNTKDTNVWEGDYQMVGRQGRGKADLMKQRGENRY-----TILDNGSFTSCLPGSDTW 180 Query: 185 CRQEGLPYAEDASNLMTEYRRNAVRLNLIPALEAYNPKVRQSLLQLSEIVQAEDEYMEAA 244 + + + + Y + ++ Sbjct: 181 SVVGSEIIHDREEQVAEIWNARFKVGPVPIFYSPYLQLPVGDKRRSGFLIPNAKYTTTNY 240 Query: 245 AQKYFNELVLADAGKCTMQRALFTAIPSALQRRLIKLILNYLSADSSSLDFPKIEAVRRG 304 + Y M + T + ++ + Sbjct: 241 FEFYLPYY---WNIAPNMDATI-TPHYMHRRGNIMWENE-------FRYLSQAGAGL-ME 288 Query: 305 TLQDYPTVWSLNMGGGLICMRQYDTIVFS 333 +F Sbjct: 289 LDYLPSDK---VYEDEHPNDDSSRRWLFY 314 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.134 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 31,711,472 Number of extensions: 1183122 Number of successful extensions: 4395 Number of sequences better than 1.0e-05: 28 Number of HSP's gapped: 4368 Number of HSP's successfully gapped: 28 Length of query: 484 Length of database: 38,378,431 Length adjustment: 110 Effective length of query: 374 Effective length of database: 25,691,691 Effective search space: 9608692434 Effective search space used: 9608692434 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 118 (50.1 bits)