BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0057.0019.p (317 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value lin0464 [K] COG2378 Predicted transcriptional regulator 72 2e-12 AGpA393 [K] COG2378 Predicted transcriptional regulator 69 1e-11 mll4985 [K] COG2378 Predicted transcriptional regulator 68 2e-11 BH1889 [K] COG2378 Predicted transcriptional regulator 67 3e-11 lin2535 [K] COG2378 Predicted transcriptional regulator 57 3e-08 >lin0464 [K] COG2378 Predicted transcriptional regulator Length = 310 Score = 71.6 bits (174), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 76/325 (23%), Positives = 146/325 (44%), Gaps = 29/325 (8%) Query: 4 KVIRIFKIINAIQSNPGITASALAIRCDVNIRTVYRDLEIISHFA-PV-TNEGRGTGYKF 61 KV R+ I+ + I+A LA R +V++RT+YRD++ I P+ + G G G++ Sbjct: 2 KVDRLMSIVLILLDKERISAQELADRFEVSLRTIYRDIDAIDLAGVPIRSTPGVGGGFEI 61 Query: 62 LGKFFLYPLDFSEQEALAFSLLPSFLNQDKIPPGFHTAYDKVMGTHLKEKSKQNGILENI 121 + + + FS + A + S L+ A K+ +++K+ + N Sbjct: 62 MPDYKMDSKVFSTADLSAILMGLSSLSNMVRGDELINALAKIKSFIPADRAKEIELKAN- 120 Query: 122 ADIIQMGKPAYRKKSRNFLQP---IIGAILEQRSIRAIYHSQSRNALTQREIDPYYLIPR 178 Q+ + N +QP II L++ + + + T R ++PY L+ + Sbjct: 121 ----QIYIDLSQWTGNNNIQPHVEIIKVALQENKLLTFEYIAHQGNKTVRIVEPYQLVMK 176 Query: 179 DQRFYLIGYCHLKQAIRTFRISRFQEVEVTDRSFDKGNFNIKKY-LKNTWSIDRGNKNIK 237 +YL GYC + R FR+SR +++ + +F +F + +++ +I I+ Sbjct: 177 SSHWYLYGYCQNRNDFRLFRLSRMSGLQILEDTFTLRDFQKPQLEMEDIVAI----MQIE 232 Query: 238 FRVRFHPEIARYIKEEELFVHPWMSDEN---DGSLLFEVT---VNNEKEFTKWILQYGPN 291 ++R H I + + + S EN DG + V+ + NE + +L +G Sbjct: 233 IKIRIHQSIIDRVLD-------YCSYENFYPDGEEHYIVSFPFIENEYHY-DILLSFGDK 284 Query: 292 AEILEPASAREGLKVQLEQWMRLYQ 316 E LEP RE +K ++ + +Y+ Sbjct: 285 CECLEPLHVREKMKRRIYDIVSIYE 309 >AGpA393 [K] COG2378 Predicted transcriptional regulator Length = 347 Score = 68.6 bits (166), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 13/214 (6%), Positives = 38/214 (17%), Gaps = 18/214 (8%) Query: 7 RIFKIINAIQSNPG-ITASALAIRCDVNIRTVYRDLEIISHFAPVTNEGRGTGYKFLGKF 65 +I +N G ++A N T + A V + Sbjct: 6 TSKSSRKSIVANFGLLSAELENRLSTDNSATPQQSTAPARVGAGVIGAAHRAIDDIKSER 65 Query: 66 FLYPLDFS--EQEALAFSLLP-SFLNQDKIPPGFHTAYDKVMGTHLKEKSKQNGILENIA 122 P + + + ++ + ++ Sbjct: 66 DRLKALVESGGGAIRELDPSKIDPSPFPDRLPDDNASDFETFRNSIRSEGQKV------- 118 Query: 123 DIIQMGKPAYRKKSRNFLQPIIG----AILEQRSIRAIYHSQSRNALTQREIDPYYLIPR 178 + + R + A + + + + Sbjct: 119 --PIQVRKSPSSPERYQVIYGHRRLRAAKDLGIPV-KAIEVEISDVELVIAQGIENADRQ 175 Query: 179 DQRFYLIGYCHLKQAIRTFRISRFQEVEVTDRSF 212 D + + + + D Sbjct: 176 DLTWIERALFARRMDDADVKPRDIKAALSIDDPE 209 >mll4985 [K] COG2378 Predicted transcriptional regulator Length = 234 Score = 67.8 bits (164), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 64/239 (26%), Positives = 98/239 (41%), Gaps = 32/239 (13%) Query: 4 KVIRIFKIINAIQ-SNPGITASALAIRCDVNIRTVYRDLEIISHFAPVTNEGRGTGYKFL 62 K R+F+II ++ + +TA+ +A R +V IR++YRD+ + GRG GY Sbjct: 6 KASRLFEIIQILRLARQPVTAAMIAERLEVTIRSIYRDIAALQAMRVPIEGGRGIGYILR 65 Query: 63 GKFFLYPLDFS--EQEALAFSL-LPSFLNQDKIPPGFHTAYDKVMGT---HLKEKSKQNG 116 F L PL FS E EA+ SL L D++ K+ G L++ N Sbjct: 66 PGFDLPPLMFSIEEMEAIVLSLALLERTGDDELKQAAKRVSSKIAGAVPPPLRQTFDANA 125 Query: 117 ILENIADIIQMGKPAYRKKSRNFLQPIIGAI---LEQRSIR-----AIYHSQSRNALTQR 168 + + F P G I L +R+IR + + TQR Sbjct: 126 L-----------------HAWGFAAPSAGTIDLALVRRAIRDEEKLDLSYRDEAGRTTQR 168 Query: 169 EIDPYYLIPRDQRFYLIGYCHLKQAIRTFRISRFQEVEVTDRSFDKGNFNIKKYLKNTW 227 I P LI + + +C L+QAIR FR R + + T F +++ W Sbjct: 169 IIRPIALIYYAEAVNTVAWCELRQAIRNFRSDRIEGCQPTGLHFKGEGDRLRQIWVEGW 227 >BH1889 [K] COG2378 Predicted transcriptional regulator Length = 325 Score = 67.0 bits (162), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 81/328 (24%), Positives = 143/328 (43%), Gaps = 31/328 (9%) Query: 3 DKVIRIFKIINAIQSNPGITASALAIRCDVNIRTVYRDLEIISHFA-PVTNE-GRGTGYK 60 K R+ +++ I T LA V+ RT+ RDL+ +S P+ +E G GY+ Sbjct: 2 SKAKRLMELMMVINRKRRFTVKELAEEFSVSSRTILRDLQELSELGVPLYSEVGPHGGYE 61 Query: 61 FLGKFFLYPLDFSEQEALA----------FSLLPSFLNQDKIPPGFHTAYDKVMGTHLKE 110 L + L P+ F+E+EA+A FS LP + F++ M +KE Sbjct: 62 VLNERVLPPIAFTEEEAVAIFFTVHALRHFSALPFQAESSSVNHKFYS----YMPEDVKE 117 Query: 111 KSKQNGILENIADIIQMGKPAYRKKSRNFLQPIIGAILEQRSIRAIYHSQSRNALTQREI 170 + Q L+N D +P + +L ++ A ++Q + Y + T+REI Sbjct: 118 RIDQ---LKNRFDFETPMRPL----ATPYLPTLLDAAIKQNVVSIEYETSQEK--TKREI 168 Query: 171 DPYYLIPRDQRFYLIGYCHLKQAIRTFRISRFQEVEVTDRSFDKG-NFNIKKYLKNTWSI 229 P + RD +Y YC L++ +R FR R VT+++ + NF +L N S Sbjct: 169 QPIGVYARDGFWYCPSYCFLREDMRLFRCDRI--TYVTEQTTNNPLNFR-HVHLGNWQSY 225 Query: 230 DRGNKNI-KFRVRFHPE-IARYIKEEELFVHPWMSDENDGSLLFEVTVNNEKEFTKWILQ 287 + +N+ F V + + R + E+ L H + + G L + F+ + + Sbjct: 226 MKQERNVLDFYVELSQDGVQRCVAEQWLKPHLHIRQDGSGWLEGPFPESEVPYFSYYFIG 285 Query: 288 YGPNAEILEPASAREGLKVQLEQWMRLY 315 +G +A + +P +K L + + Y Sbjct: 286 FGHDATVKQPVQLVTLIKKSLRELLSKY 313 >lin2535 [K] COG2378 Predicted transcriptional regulator Length = 298 Score = 57.4 bits (137), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 78/315 (24%), Positives = 132/315 (41%), Gaps = 33/315 (10%) Query: 4 KVIRIFKIINAIQSNPGITASALAIRCDVNIRTVYRDLEII--SHFAPVTNEGRGTGYKF 61 K+ RI I+ I + AS LA + +V+ RT+YRD++ + + F V G+ G+ Sbjct: 2 KLERILAILVMILERK-VLASELAEKFEVSTRTIYRDMDTLLYAGFPVVALPGKNGGFTM 60 Query: 62 LGKFFLYPLDFSEQEAL----AFSLLPSFLNQDKIPPGFHTAYDKVMGTHLKEKSKQNGI 117 L + L FSE+E A F+ D T +K+ EK N I Sbjct: 61 LDTYKLATFTFSEEEKRILLEALEARSEFMLND----SQETLREKITLLQ-TEKPTSNYI 115 Query: 118 LENIADIIQMGKPAYRKKSRNFLQPIIGAILEQRSIRAIYHSQSRNALTQREIDPYYLIP 177 + A + A K+ ++Q A ++ + Y + T REI P L Sbjct: 116 FFDSATQHRKQIEAEVKRKIAYIQK---AFTMKKQLDITYIAMDGTE-TNREISPQKLNL 171 Query: 178 RDQRFYLIGYCHLKQAIRTFRISRFQEVEVTDRSFDKGNFNIKKYLKNTWSIDRGNKNIK 237 D +YL YCH + AIR F+++R ++K+ K + I+ K + Sbjct: 172 MDGSWYLEAYCHKRAAIRHFKLTRIT--------------SLKETSKTSMKIEEDQKQAE 217 Query: 238 FRVRFHPEIAR--YIKEEELFVHPWMSDENDGSLLFEVTVNNEKEFTKWILQYGPNAEIL 295 + E + K + F+ M E D + + E+ ++L +G +IL Sbjct: 218 VTEKIVLEFPKNQLGKLLDYFLLEEMQMELD-LVRVRFQYDPERNIIPFLLMFGSAVKIL 276 Query: 296 EPASAREGLKVQLEQ 310 EPAS ++ K ++E+ Sbjct: 277 EPASLQKEYKAEVEK 291 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.322 0.139 0.413 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 23,906,350 Number of extensions: 988870 Number of successful extensions: 1426 Number of sequences better than 1.0e-05: 8 Number of HSP's gapped: 1419 Number of HSP's successfully gapped: 8 Length of query: 317 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 211 Effective length of database: 26,153,027 Effective search space: 5518288697 Effective search space used: 5518288697 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 116 (49.3 bits)