BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0057.0017.p (412 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMa2301 [T] COG2199 FOG: GGDEF domain 127 4e-29 mll2297_2 [T] COG2199 FOG: GGDEF domain 115 1e-25 sll0821_7 [T] COG2199 FOG: GGDEF domain 114 4e-25 PA3702 [T] COG3706 Response regulator containing a CheY-like rec... 113 7e-25 sll1673_3 [T] COG2199 FOG: GGDEF domain 112 8e-25 >SMa2301 [T] COG2199 FOG: GGDEF domain Length = 448 Score = 127 bits (319), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 77/186 (41%), Positives = 103/186 (55%), Gaps = 5/186 (2%) Query: 224 IRNEKVHLELARANGELQRLSLTDALTEIPNRRAFDQQMQRLLSQNEE--PGSLVAILMI 281 +R+ + ELA AN L+RL+ TD LT I NRR + + RL S E PG+ A+LM Sbjct: 255 LRDMRRVAELADANARLERLAKTDPLTGIANRRWMMETLNRLWSSGAERRPGT--AMLMC 312 Query: 282 DIDYFKPFNDNYGHAEGDRILKEVAQAIQAEMKGEGQFAARLGGEEFVAAAFDTGVDGAM 341 DID FK ND GHAEGDR L +VA IQ+ ++ AR GGEEF+ + A+ Sbjct: 313 DIDDFKSLNDRLGHAEGDRCLVKVAGIIQSSVRRNRDHVARYGGEEFLVVLPGANEEAAV 372 Query: 342 ELSERIRARVQQLAVPHEYSEVSVHLTVSX-XXXXXXXXXXXXXXQLMEHADKGLYLAKT 400 +ERIRA V+ ++P+ S V+ ++T+S +L AD LYLAK Sbjct: 373 ATAERIRASVEAASLPNPASRVAPYVTLSIGVAAQAPGEEIVAPEKLQNQADAALYLAKQ 432 Query: 401 GGRNRV 406 GRNRV Sbjct: 433 AGRNRV 438 >mll2297_2 [T] COG2199 FOG: GGDEF domain Length = 179 Score = 115 bits (289), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 67/166 (40%), Positives = 90/166 (54%), Gaps = 1/166 (0%) Query: 240 LQRLSLTDALTEIPNRRAFDQQMQRLLSQNEEPGSLVAILMIDIDYFKPFNDNYGHAEGD 299 L RLS TD LT + NRRA D++++ S ++ GS A ++ID+D+FK FND YGH EGD Sbjct: 8 LLRLSRTDPLTGLENRRAIDEKLRDYWSDWQKLGSKFAAILIDVDFFKKFNDCYGHQEGD 67 Query: 300 RILKEVAQAIQAEMKGEGQFAARLGGEEFVAAAFDTGVDGAMELSERIRARVQQLAVPHE 359 R L VA A+ +K R GGEEF+ A D EL+E I V+ LA+ HE Sbjct: 68 RCLIHVANALSDLIKNYNGSIGRYGGEEFIVLARMDKKDQVAELAEAICRTVENLAITHE 127 Query: 360 YSEVSVHL-TVSXXXXXXXXXXXXXXXQLMEHADKGLYLAKTGGRN 404 + + T S +++ AD+ LYLAK GGRN Sbjct: 128 LRRDGISIVTASVGAAFTRTQAGAKLEKIIHEADRALYLAKAGGRN 173 >sll0821_7 [T] COG2199 FOG: GGDEF domain Length = 182 Score = 114 bits (284), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 63/166 (37%), Positives = 93/166 (56%), Gaps = 1/166 (0%) Query: 240 LQRLSLTDALTEIPNRRAFDQQMQRLLSQNEEPGSLVAILMIDIDYFKPFNDNYGHAEGD 299 LQ++S DALT++ NR FD ++R + + +A+L+ D+D+FK FNDNYGH GD Sbjct: 2 LQQISSLDALTQVGNRYLFDSTLEREWQRLQRIREPLALLLCDVDFFKGFNDNYGHPAGD 61 Query: 300 RILKEVAQAIQAEMKGEGQFAARLGGEEFVAAAFDTGVDGAMELSERIRARVQQLAVPHE 359 R LK++A A+ K AR GGEEF +T ++GA+ ++E ++ V LA+PH Sbjct: 62 RCLKKIADAMAKVAKRPTDLVARYGGEEFAIILSETSLEGAINVTEALQVEVANLAIPHT 121 Query: 360 YSEVSVHLTVSXXXXXXXXXXXXXXXQLMEHADKGLYLAKTGGRNR 405 S H+T+S L++ AD LY AK GRN+ Sbjct: 122 VSGTG-HVTLSIGIAVYTPERHINPNALVKAADLALYEAKAKGRNQ 166 >PA3702 [T] COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain Length = 347 Score = 113 bits (282), Expect = 7e-25, Method: Compositional matrix adjust. Identities = 72/202 (35%), Positives = 105/202 (51%), Gaps = 3/202 (1%) Query: 206 YYNRILLGASHRKLEEQIIRNEKVHLELARANGELQRLSLTDALTEIPNRRAFDQQMQRL 265 Y++R + R + +R + +L N LQRL +D LT + NRR FD+ ++ Sbjct: 135 YHSRSYIALQQRDEAYRALRESQ--QQLLETNLVLQRLMNSDGLTGLSNRRHFDEYLEME 192 Query: 266 LSQNEEPGSLVAILMIDIDYFKPFNDNYGHAEGDRILKEVAQAIQAEMKGEGQFAARLGG 325 ++ S +++LMID+DYFK +ND +GH GD L++VA AI+ AAR GG Sbjct: 193 WRRSLREQSQLSLLMIDVDYFKSYNDTFGHVAGDEALRQVAGAIREGCSRSSDLAARYGG 252 Query: 326 EEFVAAAFDTGVDGAMELSERIRARVQQLAVPHEYSEVSVHLTVSXXXXXXXXXXXXXXX 385 EEF T GA L+E++R V+ L + H+ HLTVS Sbjct: 253 EEFAMVLPGTSPGGARLLAEKVRRTVESLQISHDQPRPGSHLTVSIGVSTLVPGGGGQTF 312 Query: 386 Q-LMEHADKGLYLAKTGGRNRV 406 + L+E AD+ LY AK GRN+V Sbjct: 313 RVLIEMADQALYQAKNNGRNQV 334 >sll1673_3 [T] COG2199 FOG: GGDEF domain Length = 176 Score = 112 bits (281), Expect = 8e-25, Method: Compositional matrix adjust. Identities = 69/177 (38%), Positives = 98/177 (55%), Gaps = 8/177 (4%) Query: 233 LARANGELQRLSLTDALTEIPNRRAFD----QQMQRLLSQNEEPGSLVAILMIDIDYFKP 288 L AN +LQ L+ D LT I NRR FD Q+ QR + ++P SL+ ++DIDYFK Sbjct: 1 LQAANQQLQLLANIDGLTHIANRRRFDEYLAQEWQRHCRE-QKPLSLI---LVDIDYFKA 56 Query: 289 FNDNYGHAEGDRILKEVAQAIQAEMKGEGQFAARLGGEEFVAAAFDTGVDGAMELSERIR 348 +ND YGH +GD L++VA + K AR GGEEFV +T A+ ++E + Sbjct: 57 YNDLYGHQKGDDCLQKVANTLVDIAKRITDLVARYGGEEFVIVLPNTNRQDALAMAENML 116 Query: 349 ARVQQLAVPHEYSEVSVHLTVSXXXXXXXXXXXXXXXQLMEHADKGLYLAKTGGRNR 405 + LA+PHE S VS ++T+S +++ AD+ LY AK+ GRNR Sbjct: 117 QAIAALAIPHEGSSVSKYVTISIGVSSIIPMPEDTIERIISEADQALYSAKSQGRNR 173 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.325 0.139 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 25,847,876 Number of extensions: 940033 Number of successful extensions: 4396 Number of sequences better than 1.0e-05: 140 Number of HSP's gapped: 4211 Number of HSP's successfully gapped: 140 Length of query: 412 Length of database: 38,378,431 Length adjustment: 109 Effective length of query: 303 Effective length of database: 25,807,025 Effective search space: 7819528575 Effective search space used: 7819528575 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 117 (49.7 bits)