BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0054.0012.p (384 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value lin0593 [R] COG0628 Predicted permease 345 5e-95 BS_yubA [R] COG0628 Predicted permease 331 1e-90 SA1192 [R] COG0628 Predicted permease 245 8e-65 SP1505 [R] COG0628 Predicted permease 221 1e-57 SPy1011 [R] COG0628 Predicted permease 211 2e-54 >lin0593 [R] COG0628 Predicted permease Length = 389 Score = 345 bits (886), Expect = 5e-95, Method: Compositional matrix adjust. Identities = 181/374 (48%), Positives = 251/374 (67%), Gaps = 1/374 (0%) Query: 10 KFKKFFLNNRFXXXXXXXXXXXXXXXXFAKIPFIFKPISVLLHTVAAPLLLSGIAYYLLN 69 KFK+FF+ N+F KI FIF P+ V+L TVAAP++L+GI+YYL N Sbjct: 7 KFKQFFIENKFVLGLLIFLLVALDIYVLTKIAFIFDPLMVILKTVAAPIILAGISYYLFN 66 Query: 70 PLVDRMEKRSKIRRPYGIVXXXXXXXXXXXXXXXXXXPMIRTQLVGLIDNFPKYSDQIQQ 129 P++D +EK+ K +R + I P ++ Q+V L +FP Y DQI Q Sbjct: 67 PIIDWLEKK-KWKRGWAIALLYLVIIGLIILLFSFVIPAVKDQIVSLFKSFPGYWDQITQ 125 Query: 130 EFIDLTGSKLFEQIQENVGTDFTDITSKVTTWGTSFLNNAVSGVGNFVGALTEIVLALVT 189 +F + + S LF+QI++ + T+ +DI ++T GTS +N+A++ +G+ VG +TE+VLA+VT Sbjct: 126 KFDEFSRSSLFDQIKDKLSTNMSDIMKTLSTKGTSVINSAITSIGSIVGTVTEVVLAIVT 185 Query: 190 TPFILFYLLRDGKRLPDYLMRFIPTALRPQTRMVMSEMNSQVASYIRGQIIVSCCXXXXX 249 TP +LFYLL+DGK+LPD+L++ +P R TR V+ E N Q++SYIRGQIIVS C Sbjct: 186 TPLVLFYLLKDGKKLPDFLLKMLPVNGRAHTRQVLGEANHQISSYIRGQIIVSLCIGILL 245 Query: 250 XXXXXXXXXXXSLVLAIVAACTAVVPYLGPAIAITPALIVALVTSPFMLLKMVCVWTAVQ 309 +L LAI+AACT++VPYLGPAIAITPA+I+A+VTSP++L+K++ VW VQ Sbjct: 246 FIGYLIIGLPYALTLAIIAACTSIVPYLGPAIAITPAIIIAIVTSPWLLIKLIIVWCVVQ 305 Query: 310 LIEGKFISPQIMGKTLKXXXXXXXXXXXFAGKMFGVLGIILAVPGYAVLKVVVTHVFQWF 369 L+EGKFISPQ+MGKTLK AG +FG+LG+I AVPGYAVLKVVVTHVF WF Sbjct: 306 LLEGKFISPQVMGKTLKVHPITILFVILVAGNLFGILGVIFAVPGYAVLKVVVTHVFIWF 365 Query: 370 RFRSGLYKQIEETK 383 + SGLY + E++ Sbjct: 366 KRVSGLYGEQPESE 379 >BS_yubA [R] COG0628 Predicted permease Length = 388 Score = 331 bits (849), Expect = 1e-90, Method: Compositional matrix adjust. Identities = 181/384 (47%), Positives = 248/384 (64%), Gaps = 3/384 (0%) Query: 1 MERLQVWPEKFKKFFLNNRFXXXXXXXXXXXXXXXXFAKIPFIFKPISVLLHTVAAPLLL 60 ME LQ W +FK+FFL+N+F F K FIF PI VLL T++ P++L Sbjct: 1 METLQTWSGRFKRFFLDNKFVLFLLVLLLIGLNILVFTKTSFIFTPIIVLLKTISLPIIL 60 Query: 61 SGIAYYLLNPLVDRMEKRSKIRRPYGIVXXXXXXXXXXXXXXXXXXPMIRTQLVGLIDNF 120 +GI +YLLNP+VD +E+R R I+ P ++ Q++ LIDN Sbjct: 61 TGIVFYLLNPVVDFLERRRIRRIYS-ILLLYLLVIGLITITIVSIIPFLKEQIMSLIDNI 119 Query: 121 PKYSDQIQQEFIDLTGSKLFEQIQENVGTDFTDITSKVTTWGTSFLNNAVSGVGNFVGAL 180 P+Y D ++ + L GS Q Q+ + + +D+ +KV+ + +N+ +GVGNF+GAL Sbjct: 120 PRYVDVVENQTKQLIGSNFVNQAQQTMNINISDLATKVSDQAATIVNSTFTGVGNFIGAL 179 Query: 181 TEIVLALVTTPFILFYLLRDGKRLPDYLMRFIPTALRPQTRMVMSEMNSQVASYIRGQII 240 TEI++++VT PFILFYLL+DG++LP Y+++F+PT L+ QT V+SEMN +++SYIRGQII Sbjct: 180 TEIIISIVTVPFILFYLLKDGRKLPVYILKFVPTRLKEQTYTVLSEMNHRLSSYIRGQII 239 Query: 241 VSCCXXXXXXXXXXXXXXXXSLVLAIVAACTAVVPYLGPAIAITPALIVALVTSPFMLLK 300 VS C + +LA++AACT++VPYLGP IAITPA+I+A+VTSP MLLK Sbjct: 240 VSFCIGFLLFIGYLIIGLDYASLLAVIAACTSIVPYLGPTIAITPAIIIAIVTSPLMLLK 299 Query: 301 MVCVWTAVQLIEGKFISPQIMGKTLKXXXXXXXXXXXFAGKMFGVLGIILAVPGYAVLKV 360 +V VWT VQLIEGK ISPQIMGK L AGK+FGV+GIILA+PGYAV KV Sbjct: 300 LVIVWTIVQLIEGKLISPQIMGKNLHIHPITIIFLLLTAGKLFGVVGIILAIPGYAVAKV 359 Query: 361 VVTHVFQWFRFRSGLYKQIEETKE 384 + TH+F WF+ +S LY EE E Sbjct: 360 ITTHLFDWFKMQSHLYD--EEKNE 381 >SA1192 [R] COG0628 Predicted permease Length = 402 Score = 245 bits (626), Expect = 8e-65, Method: Compositional matrix adjust. Identities = 131/369 (35%), Positives = 198/369 (53%), Gaps = 1/369 (0%) Query: 4 LQVWPEKFKKFFLNNRFXXXXXXXXXXXXXXXXFAKIPFIFKPISVLLHTVAAPLLLSGI 63 L+ ++ KF N F K+ ++F P ++ T+AAP+++S I Sbjct: 13 LKFTESRYMKFVGGNDLVFSLIALVLLGIVIFIFEKVSYVFDPFIIVFKTIAAPIIVSLI 72 Query: 64 AYYLLNPLVDRMEKRSKIRRPYGIVXXXXXXXXXXXXXXXXXXPMIRTQLVGLIDNFPKY 123 +YL NP+V+ ME R +I R GI P+I +Q+ L+ N P+Y Sbjct: 73 LFYLFNPIVNMME-RYRIPRVAGISIIYLAVVGVITLIVNLLIPIIGSQVDSLVKNSPQY 131 Query: 124 SDQIQQEFIDLTGSKLFEQIQENVGTDFTDITSKVTTWGTSFLNNAVSGVGNFVGALTEI 183 +++ + + F + + K+ + + F + S + F + I Sbjct: 132 LEKLINSIDKIANNTFFSSYYSQINDWLNSLPKKIPSMLSEFTDGFGSKIATFAETIANI 191 Query: 184 VLALVTTPFILFYLLRDGKRLPDYLMRFIPTALRPQTRMVMSEMNSQVASYIRGQIIVSC 243 + +VTTPF+LF++L+DG ++ +P R ++ +M+ QV SYI+GQIIVS Sbjct: 192 GVVIVTTPFVLFFMLKDGHHFKEFSTNIMPPKFRKDFHDLLEKMSVQVGSYIQGQIIVSF 251 Query: 244 CXXXXXXXXXXXXXXXXSLVLAIVAACTAVVPYLGPAIAITPALIVALVTSPFMLLKMVC 303 C SLVLA +AA T+VVPYLGP IAI+PA+++A +TSP+MLLK+ Sbjct: 252 CIGILLFIGYSVIGLKYSLVLASIAAVTSVVPYLGPTIAISPAIVIAAITSPWMLLKLAV 311 Query: 304 VWTAVQLIEGKFISPQIMGKTLKXXXXXXXXXXXFAGKMFGVLGIILAVPGYAVLKVVVT 363 VWT VQ +EG FISP IMGKTLK AGK+ G++G+IL +PGYA+LKV+VT Sbjct: 312 VWTLVQFVEGHFISPNIMGKTLKIHPLTIIFILLCAGKLLGIVGVILGIPGYAILKVLVT 371 Query: 364 HVFQWFRFR 372 H+FQ F+ R Sbjct: 372 HLFQLFKRR 380 >SP1505 [R] COG0628 Predicted permease Length = 388 Score = 221 bits (564), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 124/375 (33%), Positives = 197/375 (52%), Gaps = 2/375 (0%) Query: 11 FKKFFLNNRFXXXXXXXXXXXXXXXXFAKIPFIFKPISVLLHTVAAPLLLSGIAYYLLNP 70 F K+FL+N+ +KI F+F P+ L V P++LSG+ YYLLNP Sbjct: 13 FFKWFLDNKAITVFLVTLLLGLNLFILSKISFLFSPVLDFLAVVMLPVILSGLLYYLLNP 72 Query: 71 LVDRMEKRSKIRRPYGIVXXXXXXXXXXXXXXXXXXPMIRTQLVGLIDNFPKYSDQIQQE 130 +VD MEK K+ R I P ++ Q++ N P Y + I + Sbjct: 73 IVDWMEKH-KVNRVIAITIVFVIIALFIIWGLAVAIPNLQRQVLTFARNVPVYLEDIDRI 131 Query: 131 FIDLTGSKLFEQIQENVGTDFTDITSKVTTWGTSFLNNAVSGVGNFVGALTEIVLALVTT 190 L L + + + T+ +S+ T + + AV+ V F+ +++++AL+ Sbjct: 132 VNGLVAQHLPDDFRPQLEQVLTNFSSQATVLASKVSSQAVNWVSAFISGASQVIVALIIV 191 Query: 191 PFILFYLLRDGKRLPDYLMRFIPTALRPQTRMVMSEMNSQVASYIRGQIIVSCCXXXXXX 250 PF+LFYLLRDGK L +YL +FIP L+ V+S++N Q+++Y+RGQ+ V+ Sbjct: 192 PFMLFYLLRDGKGLRNYLTQFIPRKLKEPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFI 251 Query: 251 XXXXXXXXXXSLVLAIVAACTAVVPYLGPAIAITPALIVALVTSPFMLLKMVCVWTAVQL 310 ++ L + A +VPYLG +A+ PAL++ L+ P MLLK+V V+ Q Sbjct: 252 IFFKIIGLRYAVTLGVTAGILNLVPYLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQT 311 Query: 311 IEGKFISPQIMGKTLKXXXXXXXXXXXFAGKMFGVLGIILAVPGYAVLKVVVTHVFQWFR 370 IEG+F+SP I+G L +G MFG+ G++L +P YA KVV++ +F+W++ Sbjct: 312 IEGRFVSPLILGSQLNIHPINVLFVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYK 371 Query: 371 FRSGLYK-QIEETKE 384 SGLY+ + EE K Sbjct: 372 VVSGLYELEGEEVKS 386 >SPy1011 [R] COG0628 Predicted permease Length = 393 Score = 211 bits (536), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 120/387 (31%), Positives = 189/387 (48%), Gaps = 11/387 (2%) Query: 8 PEK------FKKFFLNNRFXXXXXXXXXXXXXXXXFAKIPFIFKPISVLLHTVAAPLLLS 61 PEK F K+FLNN+ F KI F+F P+ + PL++S Sbjct: 5 PEKSRTDSLFYKWFLNNQATMALVITLLAFLTIFVFTKISFLFMPVISFFAVIMLPLVIS 64 Query: 62 GIAYYLLNPLVDRMEKRSKIRRPYGIVXXXXXXXXXXXXXXXXXXPMIRTQLVGLIDNFP 121 I YYL PLVD + R I PM++TQL I++ P Sbjct: 65 TILYYLTKPLVDLINHLGP-NRTTSIFIVFGLITLLFVWAISGFVPMVQTQLTSFIEDLP 123 Query: 122 KYSDQIQQEFIDLTGSKLFEQIQENVGTDFTDITSKVTTWGTSFLNNAVSGVGNFVGALT 181 KY ++ +E L ++ + + T + K + SF NA+ GNF GA+ Sbjct: 124 KYVGKVNEEANKLLENEWLVSYKPQLQDMLTHTSQKALDYAQSFSKNAIDWAGNFAGAIA 183 Query: 182 EIVLALVTTPFILFYLLRDGKRLPDYLMRFIPTALRPQTRMVMSEMNSQVASYIRGQIIV 241 I +A++ +PFILFY LRD + + L+ +P LR V+ ++N Q++ Y++GQ+ V Sbjct: 184 RITVAIIISPFILFYFLRDSSHMKNGLVNVLPLKLRVPMVRVLGDINKQLSGYVQGQVTV 243 Query: 242 SCCXXXXXXXXXXXXXXXXSLVLAIVAACTAVVPYLGPAIAITPALIVALVTSPFMLLKM 301 + ++ I+A ++PYLG +A+ P +I+A+V PFML+K+ Sbjct: 244 AIVVGFMFSIMFSLVGLKYAITFGIIAGFLNMIPYLGSFLAMIPVVIMAMVQGPFMLVKV 303 Query: 302 VCVWTAVQLIEGKFISPQIMGKTLKXXXXXXXXXXXFAGKMFGVLGIILAVPGYAVLKVV 361 + ++ Q IEG+F++P ++G L AG MFGV G+ L +P YA +KVV Sbjct: 304 LVIFMIEQTIEGRFVAPLVLGNKLSIHPITIMFLLLTAGSMFGVWGVFLVIPIYASVKVV 363 Query: 362 VTHVFQWFRFRSGLYKQ----IEETKE 384 + +F W++ SGLY + IEE K+ Sbjct: 364 IKELFDWYKKVSGLYDEEVLVIEEVKD 390 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.328 0.142 0.424 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 22,085,636 Number of extensions: 704309 Number of successful extensions: 2017 Number of sequences better than 1.0e-05: 71 Number of HSP's gapped: 1922 Number of HSP's successfully gapped: 71 Length of query: 384 Length of database: 38,378,431 Length adjustment: 108 Effective length of query: 276 Effective length of database: 25,922,359 Effective search space: 7154571084 Effective search space used: 7154571084 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 117 (49.7 bits)