BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0044.0020.p
         (516 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

slr0993 [M] COG0739 Membrane proteins related to metalloendopept...   120   4e-27
alr3353 [M] COG0739 Membrane proteins related to metalloendopept...   116   8e-26
CC1872 [M] COG0739 Membrane proteins related to metalloendopepti...   112   2e-24
XF0805 [M] COG0739 Membrane proteins related to metalloendopepti...   108   2e-23
AGc3364 [M] COG0739 Membrane proteins related to metalloendopept...   107   6e-23

>slr0993 [M] COG0739 Membrane proteins related to metalloendopeptidases
          Length = 715

 Score =  120 bits (302), Expect = 4e-27,   Method: Compositional matrix adjust.
 Identities = 66/147 (44%), Positives = 90/147 (61%), Gaps = 7/147 (4%)

Query: 375 VVQASLPEVVYRGTKVVGEGTGMF---AWPVSGATISSSYGERWGRVHKGVDLVSGNRT- 430
           V+Q   PE+    T       G F    WP  G   +S +G RWGR+H+G+D+ +   T 
Sbjct: 566 VIQEVSPELPGLSTPDFPRSPGQFNGYIWPAKG-VFTSGFGPRWGRMHRGIDIAAPIGTP 624

Query: 431 IKAADAGTVSFAGVQNG-YGNVVIVDHHNGYITYYGHLSRISVSQGQRLEQGSPIGIMGS 489
           I AA +G V F+G  +G +GN+V + H +G +TYY H +R+ V +G+ +EQG  I  MGS
Sbjct: 625 IMAAASGEVVFSGWNSGGFGNLVKIRHGDGSVTYYAHNNRLLVRRGEYVEQGQQIAEMGS 684

Query: 490 TGRSTGTHLHFEIRKNGT-AINPMKYL 515
           TGRSTG HLHFEIR  GT A+NP+  L
Sbjct: 685 TGRSTGPHLHFEIRVGGTNAVNPVALL 711


>alr3353 [M] COG0739 Membrane proteins related to metalloendopeptidases
          Length = 359

 Score =  116 bits (291), Expect = 8e-26,   Method: Compositional matrix adjust.
 Identities = 0/162 (0%), Positives = 0/162 (0%), Gaps = 6/162 (3%)

Query: 358 LTKENGQVVKEEWLGQTVVQASLPEVVYRGTKVVGEGTGMFAWPVSGATISSSYGERWGR 417
                                                                       
Sbjct: 593 -                                                            651

Query: 418 VHKGVDLVS--GNRTIKAADAGTVSFAG-VQNGYGNVVIVDHHNGYITYYGHLSRISVSQ 474
                                                                       
Sbjct: 652 -                                                            710

Query: 475 GQRLEQGSPIGIMGSTGRSTGTHLHFEIRKNGT-AINPMKYL 515
                                                     
Sbjct: 711                                            752


>CC1872 [M] COG0739 Membrane proteins related to metalloendopeptidases
          Length = 383

 Score =  112 bits (279), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 60/126 (47%), Positives = 76/126 (60%), Gaps = 7/126 (5%)

Query: 398 FAWPVSGATISSSYGERWG------RVHKGVDLVSGNRT-IKAADAGTVSFAGVQNGYGN 450
           F  P S   +SSSYG R+         H G+D   G  T I A   G +SF GV++GYG 
Sbjct: 249 FYRPTSNPALSSSYGVRFDPFTRRPAFHSGLDFPGGYHTPIMATAPGVISFTGVRSGYGK 308

Query: 451 VVIVDHHNGYITYYGHLSRISVSQGQRLEQGSPIGIMGSTGRSTGTHLHFEIRKNGTAIN 510
            V +DH  G+ T Y HL+ ISV  GQR+  GS +G MGSTGRSTG HLH+E+  NG A N
Sbjct: 309 TVEIDHGGGFKTRYAHLAAISVRVGQRVAIGSRVGGMGSTGRSTGPHLHYEVWVNGKAQN 368

Query: 511 PMKYLQ 516
           P ++L+
Sbjct: 369 PNRFLK 374


>XF0805 [M] COG0739 Membrane proteins related to metalloendopeptidases
          Length = 319

 Score =  108 bits (271), Expect = 2e-23,   Method: Compositional matrix adjust.
 Identities = 59/123 (47%), Positives = 80/123 (65%), Gaps = 9/123 (7%)

Query: 401 PVSGATISSSYGERW----GRV--HKGVDLVS--GNRTIKAADAGTVSFAGVQNGYGNVV 452
           PV  + I+S++G R     G V  HKGVD  +  G+  +  AD G VS+AG +NGYGNVV
Sbjct: 181 PVRNSYITSNFGRRADPFNGGVAEHKGVDFHASVGSSVMAVAD-GVVSYAGYRNGYGNVV 239

Query: 453 IVDHHNGYITYYGHLSRISVSQGQRLEQGSPIGIMGSTGRSTGTHLHFEIRKNGTAINPM 512
            VDH NGY+T Y H SR++V  G  +  G  +   GS+GRSTG H+HFE+ K+G  +NP+
Sbjct: 240 DVDHSNGYLTRYAHNSRLTVKVGDLVRTGQEVAKAGSSGRSTGAHVHFEVWKDGVVMNPI 299

Query: 513 KYL 515
           K+L
Sbjct: 300 KFL 302


>AGc3364 [M] COG0739 Membrane proteins related to metalloendopeptidases
          Length = 289

 Score =  107 bits (266), Expect = 6e-23,   Method: Compositional matrix adjust.
 Identities = 0/125 (0%), Positives = 0/125 (0%), Gaps = 7/125 (5%)

Query: 398 FAWPVSGATISSSYGERW----GR--VHKGVDL-VSGNRTIKAADAGTVSFAGVQNGYGN 450
                                                                       
Sbjct: 297                                                              356

Query: 451 VVIVDHHNGYITYYGHLSRISVSQGQRLEQGSPIGIMGSTGRSTGTHLHFEIRKNGTAIN 510
                                                                       
Sbjct: 357                                                              416

Query: 511 PMKYL 515
                
Sbjct: 417       421


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.313    0.131    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 32,233,239
Number of extensions: 1296607
Number of successful extensions: 2321
Number of sequences better than 1.0e-05: 122
Number of HSP's gapped: 2263
Number of HSP's successfully gapped: 122
Length of query: 516
Length of database: 38,378,431
Length adjustment: 111
Effective length of query: 405
Effective length of database: 25,576,357
Effective search space: 10358424585
Effective search space used: 10358424585
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 118 (50.1 bits)