BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0044.0019.p (243 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SA0017 [TK] COG0745 Response regulators consisting of a CheY-lik... 282 3e-76 lin0315 [TK] COG0745 Response regulators consisting of a CheY-li... 274 9e-74 ML0125 [GC] COG1819 Glycosyl transferases, related to UDP-glucur... 262 3e-70 L0125 [TK] COG0745 Response regulators consisting of a CheY-like... 262 3e-70 SP1227 [TK] COG0745 Response regulators consisting of a CheY-lik... 259 2e-69 >SA0017 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 235 Score = 282 bits (722), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 142/238 (59%), Positives = 177/238 (74%), Gaps = 6/238 (2%) Query: 1 MQMG-TILVVDDEQPIADILKFNLEKEGYEVICAFDGNSAVELALSKRXXXXXXXXXXXG 59 MQM ++VVDDE+PIADIL+FNL+KEGY+V CA+DGN AV+L + G Sbjct: 1 MQMARKVVVVDDEKPIADILEFNLKKEGYDVYCAYDGNDAVDLIYEEEPDIVLLDIMLPG 60 Query: 60 KDGMDVCREVRSAHLDIPIIMLTAKDGEIDKVLGLELGADDYVTKPFSTRELLARVKAQM 119 +DGM+VCREVR + ++PIIMLTAKD EIDKVLGLELGADDYVTKPFSTREL+ARVKA + Sbjct: 61 RDGMEVCREVRKKY-EMPIIMLTAKDSEIDKVLGLELGADDYVTKPFSTRELIARVKANL 119 Query: 120 RRQHKPAPSEALSEPLESKQGIHHFGLFVDTDMYMVYKEGEPLDLTHREYELLYYMIRHA 179 RR + S+ + I + + D Y + K GE ++LTHRE+EL +Y+ +H Sbjct: 120 RRHY----SQPAQDTGNVTNEITIKDIVIYPDAYSIKKRGEDIELTHREFELFHYLSKHM 175 Query: 180 GKVMTREHLLQAVWGFEYFGDVRTVDVTIRRLREKIEENPSKPEYIFTRRGLGYLMHS 237 G+VMTREHLLQ VWG++YFGDVRTVDVTIRRLREKIE++PS PEYI TRRG+GY + Sbjct: 176 GQVMTREHLLQTVWGYDYFGDVRTVDVTIRRLREKIEDDPSHPEYIVTRRGVGYFLQQ 233 >lin0315 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 237 Score = 274 bits (701), Expect = 9e-74, Method: Compositional matrix adjust. Identities = 137/240 (57%), Positives = 177/240 (73%), Gaps = 4/240 (1%) Query: 1 MQMGTILVVDDEQPIADILKFNLEKEGYEVICAFDGNSAVELALSKRXXXXXXXXXXXGK 60 M ILVVDDE+PIADI+KFNL KEG++V CA+DG+ A+EL + G+ Sbjct: 1 MAEKKILVVDDEKPIADIVKFNLNKEGFDVYCAYDGDEALELVEEVQPDLILLDIMLPGR 60 Query: 61 DGMDVCREVRSAHLDIPIIMLTAKDGEIDKVLGLELGADDYVTKPFSTRELLARVKAQMR 120 DG++VCREVR + D+PIIM+TAKD EIDKV+GLELGADDYVTKPFS REL+ARVKA +R Sbjct: 61 DGIEVCREVRKKY-DMPIIMVTAKDSEIDKVIGLELGADDYVTKPFSNRELIARVKANLR 119 Query: 121 RQHKPAPSEALSEPLESKQGIHHFGLFVDTDMYMVYKEGEPLDLTHREYELLYYMIRHAG 180 R + + + A E + L + D Y+ K GE ++LTHRE+ELL+Y+ +H G Sbjct: 120 RHSQVSSNAAEEE---ENSELEIGSLIIHPDAYVASKRGETIELTHREFELLHYLAKHMG 176 Query: 181 KVMTREHLLQAVWGFEYFGDVRTVDVTIRRLREKIEENPSKPEYIFTRRGLGYLMHSPKS 240 +VMTREHLLQ VWG++YFGDVRTVDVT+RRLREKIE+NPS P ++ TRRG+GY + +P+ Sbjct: 177 QVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPAWLVTRRGVGYYLRNPEQ 236 >ML0125 [GC] COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase Length = 233 Score = 262 bits (670), Expect = 3e-70, Method: Compositional matrix adjust. Identities = 132/236 (55%), Positives = 170/236 (72%), Gaps = 5/236 (2%) Query: 3 MGTILVVDDEQPIADILKFNLEKEGYEVICAFDGNSAVELALSKRXXXXXXXXXXXGKDG 62 M ILVVDDE+PI+DI+KFNL KEG+EV AFDG A+E + DG Sbjct: 1 MKKILVVDDEKPISDIVKFNLTKEGFEVFTAFDGEEALEAFKEVQPDLILLDLMLPKLDG 60 Query: 63 MDVCREVRSAHLDIPIIMLTAKDGEIDKVLGLELGADDYVTKPFSTRELLARVKAQMRRQ 122 +DV RE+R D PIIM++AKD E DKV+GLELGADDYVTKPFS RELLAR+KA +RR Sbjct: 61 LDVAREIRKTS-DTPIIMVSAKDSEFDKVIGLELGADDYVTKPFSNRELLARIKANLRRI 119 Query: 123 HKPAPSEALSEPLESKQGIHHFGLFVDTDMYMVYKEGEPLDLTHREYELLYYMIRHAGKV 182 + AP+E+ K+ + L ++ Y YK + LDLTHRE+ELLYY+ +H G+V Sbjct: 120 N-VAPAESTDN---VKKELIIGNLRINPAHYAAYKNDKQLDLTHREFELLYYLAQHLGEV 175 Query: 183 MTREHLLQAVWGFEYFGDVRTVDVTIRRLREKIEENPSKPEYIFTRRGLGYLMHSP 238 +TRE+LL+ VWG++YFGDVRTVDVT+RRLREK+E+ PS+P+Y+ TRRG+GY M +P Sbjct: 176 ITRENLLETVWGYDYFGDVRTVDVTVRRLREKVEDTPSRPQYVSTRRGVGYYMSNP 231 >L0125 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 233 Score = 262 bits (670), Expect = 3e-70, Method: Compositional matrix adjust. Identities = 132/236 (55%), Positives = 170/236 (72%), Gaps = 5/236 (2%) Query: 3 MGTILVVDDEQPIADILKFNLEKEGYEVICAFDGNSAVELALSKRXXXXXXXXXXXGKDG 62 M ILVVDDE+PI+DI+KFNL KEG+EV AFDG A+E + DG Sbjct: 1 MKKILVVDDEKPISDIVKFNLTKEGFEVFTAFDGEEALEAFKEVQPDLILLDLMLPKLDG 60 Query: 63 MDVCREVRSAHLDIPIIMLTAKDGEIDKVLGLELGADDYVTKPFSTRELLARVKAQMRRQ 122 +DV RE+R D PIIM++AKD E DKV+GLELGADDYVTKPFS RELLAR+KA +RR Sbjct: 61 LDVAREIRKTS-DTPIIMVSAKDSEFDKVIGLELGADDYVTKPFSNRELLARIKANLRRI 119 Query: 123 HKPAPSEALSEPLESKQGIHHFGLFVDTDMYMVYKEGEPLDLTHREYELLYYMIRHAGKV 182 + AP+E+ K+ + L ++ Y YK + LDLTHRE+ELLYY+ +H G+V Sbjct: 120 N-VAPAESTDN---VKKELIIGNLRINPAHYAAYKNDKQLDLTHREFELLYYLAQHLGEV 175 Query: 183 MTREHLLQAVWGFEYFGDVRTVDVTIRRLREKIEENPSKPEYIFTRRGLGYLMHSP 238 +TRE+LL+ VWG++YFGDVRTVDVT+RRLREK+E+ PS+P+Y+ TRRG+GY M +P Sbjct: 176 ITRENLLETVWGYDYFGDVRTVDVTVRRLREKVEDTPSRPQYVSTRRGVGYYMSNP 231 >SP1227 [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Length = 234 Score = 259 bits (663), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 134/238 (56%), Positives = 171/238 (71%), Gaps = 9/238 (3%) Query: 3 MGTILVVDDEQPIADILKFNLEKEGYEVICAFDGNSAVELALSKRXXXXXXXXXXXGKDG 62 M IL+VDDE+PI+DI+KFN+ KEGYEV+ AF+G A+E +++ DG Sbjct: 1 MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAEQPDIIILDLMLPEIDG 60 Query: 63 MDVCREVRSAHLDIPIIMLTAKDGEIDKVLGLELGADDYVTKPFSTRELLARVKAQMRRQ 122 ++V + +R +PI+ML+AKD E DKV+GLELGADDYVTKPFS REL ARVKA +RR Sbjct: 61 LEVAKTIRKTS-SVPILMLSAKDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRS 119 Query: 123 HKPAP---SEALSEPLESKQGIHHFGLFVDTDMYMVYKEGEPLDLTHREYELLYYMIRHA 179 +P P EA S+P Q I L + D Y+ K GE LDLTHRE+ELLY++ H Sbjct: 120 -QPMPVDGQEADSKP----QPIQIGDLEIVPDAYVAKKYGEELDLTHREFELLYHLASHT 174 Query: 180 GKVMTREHLLQAVWGFEYFGDVRTVDVTIRRLREKIEENPSKPEYIFTRRGLGYLMHS 237 G+V+TREHLL+ VWG++YFGDVRTVDVT+RRLREKIE+ PS+PEYI TRRG+GY M + Sbjct: 175 GQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMRN 232 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.320 0.139 0.406 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 17,545,916 Number of extensions: 675446 Number of successful extensions: 2687 Number of sequences better than 1.0e-05: 323 Number of HSP's gapped: 2275 Number of HSP's successfully gapped: 324 Length of query: 243 Length of database: 38,378,431 Length adjustment: 103 Effective length of query: 140 Effective length of database: 26,499,029 Effective search space: 3709864060 Effective search space used: 3709864060 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 114 (48.5 bits)