BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0044.0018.p (610 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value lin2643 [T] COG0642 Signal transduction histidine kinase 232 1e-60 lin2061 [T] COG0642 Signal transduction histidine kinase 221 2e-57 SA1322 [T] COG0642 Signal transduction histidine kinase 218 2e-56 SA1515 [T] COG0642 Signal transduction histidine kinase 211 4e-54 BS_phoR_3 [T] COG0642 Signal transduction histidine kinase 206 6e-53 >lin2643 [T] COG0642 Signal transduction histidine kinase Length = 182 Score = 232 bits (592), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 0/463 (0%), Positives = 0/463 (0%), Gaps = 19/463 (4%) Query: 149 VAKPVLSGDKVVGAIYIAADMKDLYATISRINSVFXXXXXXXXXXXXXXXXXXXHTITHP 208 Sbjct: 139 198 Query: 209 IKEMTRHATAVAEGRYNRKMPVFGNDEIGQLSQAFNYMTGRLRDALSQNEEEKEKLASIL 268 Sbjct: 199 258 Query: 269 ANMSDGVVATDESGGVILMNTRAAHMLGSEGPLPEGAPLDELLGLDHEQSGSLAQ---GN 325 Sbjct: 259 ------- 311 Query: 326 AQSAMLHLSPMGGEDPN--IVRVTFTPIHRREGGGIAGTIAVLQDVTEQENLEESRREFV 383 Sbjct: 312 - 370 Query: 384 ANVSHELRTPLTTIKSYAEALDDGALEDPQLAVRFVGVIRNETERMIRLVTDLLHLSRLD 443 Sbjct: 371 430 Query: 444 SKESSLRIQQTDISEMLEDVADRFSFQIRQKRIHISTRVREDVASAWL---DRDQIDQVL 500 Sbjct: 431 -- 488 Query: 501 GNLVSNALKYTPEGGMIQLEALKNEEGMLAISVRDSGIGIPKKDIERIFERFYRVDKARS 560 Sbjct: 489 - 547 Query: 561 RNMGGTGLGLSIAREIVKAHGGSISLQSELNEGSLVIFTLPLK 603 Sbjct: 548 590 >lin2061 [T] COG0642 Signal transduction histidine kinase Length = 182 Score = 221 bits (564), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 0/410 (0%), Positives = 0/410 (0%), Gaps = 26/410 (6%) Query: 205 ITHPIKEMTRHATAVAEGRYNRKMPVFGNDEIGQLSQAFNYMTGRLRDALSQNEEEKEKL 264 Sbjct: 199 258 Query: 265 ASILANMSDGVVATDESGGVILMNTRAAHMLGSEGPLPEG-------APLDELLGLDHEQ 317 Sbjct: 259 ------ 312 Query: 318 SGSLAQGNAQSAMLHLSPMGGEDPNIVRVTFTPIHRREGGGIAGTIAVLQDVTEQENLEE 377 Sbjct: 313 -------- 364 Query: 378 SRREFVANVSHELRTPLTTIKSYAEALDDGALEDPQLAVRFVGVIRNETERMIRLVTDLL 437 Sbjct: 365 424 Query: 438 HLSRLDSKESSLRIQQTDISEMLEDVADRFSFQIRQKRIHISTRVREDVASAWLDRDQID 497 Sbjct: 425 484 Query: 498 QVLGNLVSNALKYTPE----GGMIQLEALKNEEGMLAISVRDSGIGIPKKDIERIFERFY 553 Sbjct: 485 544 Query: 554 RVDKARSRNMG-GTGLGLSIAREIVKAHGGSISLQSELNEGSLVIFTLPL 602 Sbjct: 545 594 >SA1322 [T] COG0642 Signal transduction histidine kinase Length = 588 Score = 218 bits (555), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 139/404 (34%), Positives = 235/404 (58%), Gaps = 29/404 (7%) Query: 205 ITHPIKEMTRHATAVAEGRYNRKMPVFGNDEIGQLSQAFNYMTGRLR---DALSQNEEEK 261 IT P++ + AT V+EG Y+ K V DEIGQLSQAFN M+ + DALS ++ + Sbjct: 204 ITKPLRRLRDQATRVSEGDYSYKPSVTTKDEIGQLSQAFNQMSTEIEEHVDALSTSKNIR 263 Query: 262 EKLASILANMSDGVVATDESGGVILMNTRAAHMLGSEGPLPEGAPLDELLGLDHEQSGSL 321 + S++ +M +GV+ +ES +IL N A ++ + + E A L ++ Sbjct: 264 D---SLINSMVEGVLGINESRQIILSNKMANDIMDN---IDEDAKAFLLRQIED------ 311 Query: 322 AQGNAQSAMLHLSPMGGEDPNIVRVTFTPIHRREGGGIAGTIAVLQDVTEQENLEESRRE 381 + Q+ M L + VT + I + E GG +G + ++D+T + NL++ +++ Sbjct: 312 TFKSKQTEMRDLEM----NARFFVVTTSYIDKIEQGGKSGVVVTVRDMTNEHNLDQMKKD 367 Query: 382 FVANVSHELRTPLTTIKSYAEALDDGALEDPQLAVRFVGVIRNETERMIRLVTDLLHLSR 441 F+ANVSHELRTP++ ++ Y E++ DG + +P + V+ +E++R+ RLV +LL+++R Sbjct: 368 FIANVSHELRTPISLLQGYTESIVDGIVTEPDEIKESLAVVLDESKRLNRLVNELLNVAR 427 Query: 442 LDSKESSLRIQQTDISEMLEDVADRFSFQIRQKRIHISTRVREDVAS--AW-LDRDQIDQ 498 +D++ S+ + I+ +L D+ + RQ+ + + + W D D++DQ Sbjct: 428 MDAEGLSVNKEVQPIAALL----DKMKIKYRQQADDLGLNMTFNYCKKRVWSYDMDRMDQ 483 Query: 499 VLGNLVSNALKYTPEGGMIQLEALKNE-EGMLAISVRDSGIGIPKKDIERIFERFYRVDK 557 VL NL+ NA +YT G I + +NE E +L I +D+G GI + ++++F+RFY+VD Sbjct: 484 VLTNLIDNASRYTKPGDEIAITCDENESEDILYI--KDTGTGIAPEHLQQVFDRFYKVDA 541 Query: 558 ARSRNMGGTGLGLSIAREIVKAHGGSISLQSELNEGSLVIFTLP 601 AR+R GTGLGL I + I++ HGGSI ++SEL +G+ I LP Sbjct: 542 ARTRGKQGTGLGLFICKMIIEEHGGSIDVKSELGKGTTFIIKLP 585 >SA1515 [T] COG0642 Signal transduction histidine kinase Length = 554 Score = 211 bits (536), Expect = 4e-54, Method: Compositional matrix adjust. Identities = 140/416 (33%), Positives = 219/416 (52%), Gaps = 37/416 (8%) Query: 204 TITHPIKEMTRHATAVAEGRYNRKMPVFGNDEIGQLSQAFNYMTGRLRDALSQNEEEKEK 263 T+ PI+E+T +A G Y+ ++P E L + N + RL+ ++ + + + Sbjct: 156 TLIRPIQEVTYATQLLANGYYHIRVPESNVVETKALFVSTNDLARRLQKLNNEQKIQSNR 215 Query: 264 LASILANMSDGVVATDESGGVILMNTRAAHMLGSEGPLPEGAPLDELLGLDH--EQSGSL 321 L + + N+ ++ D +G +++ N +A + E + H EQ G Sbjct: 216 LKTTIENIPSAILMIDRNGKIVVAN-KAYY---------------EQFNISHNIEQVGYH 259 Query: 322 AQGNAQSAMLHLSPMGGEDP--------------NIVRVTFTPIHRREGGGIAGTIAVLQ 367 N + L L E P ++ PI R + G + V+ Sbjct: 260 GYVNTEIEQLILESFKVEKPIYEQLEVAINQVHAKYFDISCVPILTRSQKSLQGILVVMH 319 Query: 368 DVTEQENLEESRREFVANVSHELRTPLTTIKSYAEALDDGALEDPQLAVRFVGVIRNETE 427 D+T + LE RREFVANVSHEL+TP+T+IK +AE L DGA D + F+ +I E+ Sbjct: 320 DITNLKQLENLRREFVANVSHELKTPITSIKGFAETLIDGAKNDAESLDMFLNIILKESN 379 Query: 428 RMIRLVTDLLHLSRLDSKESSLRIQQTDISEMLEDVADRFSFQIRQKRIHISTRVREDVA 487 R+ LVTDLL LS ++ + + L ++S++ + D Q QK I I T + +DV Sbjct: 380 RIESLVTDLLDLSHIE-QHTELDTDYMNLSDLTRRIIDNMMTQANQKNISIHTDIEKDVI 438 Query: 488 SAWLDRDQIDQVLGNLVSNALKYTPEGGMIQLEALKNEEGMLAISVRDSGIGIPKKDIER 547 +I QV+ NL++NA+ Y+ E G I + +++ ++ V+D GIGI +D +R Sbjct: 439 VK-AQESKIAQVITNLLTNAINYSYEDGDINVRVYRDDFRVI-FEVQDFGIGIKLEDQQR 496 Query: 548 IFERFYRVDKARSRNMGGTGLGLSIAREIVKAHGGSISLQSELNEGSLVIFTLPLK 603 IFERFYRVDKARSR+ GGTGLGLSI + IV+AH G+I + S++ +GS F + LK Sbjct: 497 IFERFYRVDKARSRDSGGTGLGLSITKHIVEAHQGNIEVNSQVGKGS--TFKVILK 550 >BS_phoR_3 [T] COG0642 Signal transduction histidine kinase Length = 431 Score = 206 bits (525), Expect = 6e-53, Method: Compositional matrix adjust. Identities = 16/244 (6%), Positives = 49/244 (20%), Gaps = 3/244 (1%) Query: 361 GTIAVLQDVTEQENLEESRREFVANVSHELRTPLTTIKSYAEALDDGALEDPQLAVRFVG 420 + + R TP S+ L + R Sbjct: 33 WFLLASVTGLLIWHFWNLLRLSWWLWVDRSMTPPPGRGSWEPLLYGLHQMQLRNKKRRRE 92 Query: 421 VIRNETERMIRLVTDLLHLSRLDSKESSLRIQQTDISEMLEDVADRFSFQIRQKRIHIST 480 + + + + + + I + Sbjct: 93 LGNLIKRFRSGAESLPDAVVLTTEEGGIFWCNGLAQQILGLRWPEDNGQNILNLLRYPEF 152 Query: 481 RVREDVASAWLDRDQIDQVLGNLVSNALKYTPEGGMIQLEALKNEEGMLAISVRDSGIGI 540 + + +L + YT + ++ + L + R+ + Sbjct: 153 TQYLKTRDFSRPLNLVLNTGRHLEIRVMPYTHKQLLMVAR-DVTQMHQLEGARRNFFANV 211 Query: 541 PKKDIERIFERFYRVDKARSRNMGGTGLGLSIAREIVKAHGGSISLQSELNEGSLVIFTL 600 + + ++ + + G ++ + ++ L I Sbjct: 212 SHELRTPLTVLQGYLEMMNEQPLEGAVREKALHTMREQTQRMEGLVKQLLTLSK--IEAA 269 Query: 601 PLKQ 604 P Sbjct: 270 PTHL 273 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.315 0.132 0.357 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 39,985,005 Number of extensions: 1679179 Number of successful extensions: 5622 Number of sequences better than 1.0e-05: 296 Number of HSP's gapped: 5020 Number of HSP's successfully gapped: 297 Length of query: 610 Length of database: 38,378,431 Length adjustment: 112 Effective length of query: 498 Effective length of database: 25,461,023 Effective search space: 12679589454 Effective search space used: 12679589454 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 119 (50.4 bits)