BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0044.0009.p (592 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO1914 [V] COG1132 ABC-type multidrug transport system, ATPase ... 156 7e-38 PAB2147 [V] COG1132 ABC-type multidrug transport system, ATPase ... 156 8e-38 all2146 [V] COG1132 ABC-type multidrug transport system, ATPase ... 155 2e-37 all2676 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, ... 155 2e-37 PM0861 [V] COG1132 ABC-type multidrug transport system, ATPase a... 154 3e-37 >YPO1914 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 600 Score = 156 bits (395), Expect = 7e-38, Method: Compositional matrix adjust. Identities = 112/357 (31%), Positives = 172/357 (48%), Gaps = 38/357 (10%) Query: 219 FVASYEADERLVARTDGALRRWARARMFIGQAV---VGIAVVSIIYWAAGEYQSGAIAGT 275 +A + A E L RT R+ A A M I V + + V+S I W + GT Sbjct: 233 LLAHFNALENLQTRTH---RQGAGATMLIASVVELGLQVVVLSGIVWV--------VTGT 281 Query: 276 LIAAFVLVVF--------PVADAFLPVSEAVEKIPQYRNSLERLNXXXXXXXXXXXXXXX 327 L AF++ P+A F+ + VE I +ER Sbjct: 282 LNLAFLIAAVAMIMRFAEPMA-MFISYTSVVELIASALQRIERF--------------MA 326 Query: 328 XXXXXXXXKIQSTRQVHIQLKNTGYRYASGEDWSIQDLNLDIPQGRKIAIIGRSGAGKST 387 + + + I+ N YRY G+ ++ ++L P A++G SGAGK+T Sbjct: 327 IAPLPVAEQSEMPERYDIRFDNVSYRYEEGDGHALNHVSLTFPAASMSALVGASGAGKTT 386 Query: 388 LLKVIQGVIAPSVGSAVINGIAASAYG-EDIPKLIAVLNQSPHLFDTTVANNIRLGKPDA 446 + K++ P G I G+ E + LI+V+ Q LFD T+ NIR+ +P A Sbjct: 387 VTKLLMRYADPQQGQISIGGVDIRRLTPEQLNSLISVVFQDVWLFDDTLLANIRIARPQA 446 Query: 447 SDEEVKQAGKLAQLDDLISSLPEGYDTPVREAGQRFSGGERQRIALARILLQNTPAVVLD 506 + +EV++A + AQ + IS LP+G+ TP+ E G + SGGERQRI++AR LL+N P V+LD Sbjct: 447 TRQEVEEAARAAQCLEFISRLPQGWLTPMGEMGGQLSGGERQRISIARALLKNAPVVILD 506 Query: 507 EPTVGLDPRTERELLATMFTAMADKTLIWVTHHLVGAEQMDEVIFMENGTVEMRGTH 563 EPT LD +E + + + ++T+I + H L ++ ME G V +GTH Sbjct: 507 EPTAALDIESELAVQKAIDNLVHNRTVIIIAHRLSTIAGAGNILVMEEGQVVEQGTH 563 >PAB2147 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 579 Score = 156 bits (395), Expect = 8e-38, Method: Compositional matrix adjust. Identities = 81/215 (37%), Positives = 133/215 (61%), Gaps = 2/215 (0%) Query: 344 HIQLKNTGYRYASGEDWSIQDLNLDIPQGRKIAIIGRSGAGKSTLLKVIQGVIAPSVGSA 403 I+ ++ Y +G ++ ++ + G K+ I G G+GKS++LK+I P+ G Sbjct: 338 EIEFRDVWLTYHTGRTV-LKGVSFKVKPGEKVLITGPPGSGKSSILKLIARFYKPTKGEV 396 Query: 404 VINGI-AASAYGEDIPKLIAVLNQSPHLFDTTVANNIRLGKPDASDEEVKQAGKLAQLDD 462 +I+G+ A E++ K++A + Q P +F+ ++ NI L KP+A+ EEV++A K+A++ D Sbjct: 397 LIDGVNVAKIKTENLRKIVAYVPQEPFIFNRSIRENIALAKPNATQEEVERAAKIAKIHD 456 Query: 463 LISSLPEGYDTPVREAGQRFSGGERQRIALARILLQNTPAVVLDEPTVGLDPRTERELLA 522 I+SLP+GYDT V E G SGG+RQRIALAR +L N V+LD+P LD TE++L+ Sbjct: 457 FIASLPKGYDTVVGEKGITLSGGQRQRIALARAMLMNPKIVLLDDPVSNLDAETEKKLVE 516 Query: 523 TMFTAMADKTLIWVTHHLVGAEQMDEVIFMENGTV 557 + + DKT + V+ L + +D VI M++G + Sbjct: 517 DLKEILQDKTALIVSQRLSLVKLVDRVIVMKDGKI 551 >all2146 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 597 Score = 155 bits (391), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 87/220 (39%), Positives = 128/220 (58%), Gaps = 2/220 (0%) Query: 345 IQLKNTGYRYASGEDWSIQDLNLDIPQGRKIAIIGRSGAGKSTLLKVIQGVIAPSVGSAV 404 + KN + Y + E I+DL+L IP G IA++G +G+GKSTL+K++ S GS Sbjct: 358 VDFKNVTFAYQNSE-VIIKDLSLHIPAGNTIAVVGSTGSGKSTLVKLLLRFYDVSHGSIT 416 Query: 405 INGIAASAYG-EDIPKLIAVLNQSPHLFDTTVANNIRLGKPDASDEEVKQAGKLAQLDDL 463 I+GI D+ + I +++Q LF TVA NI G DASDE + A K+A+ D Sbjct: 417 IDGIDIQKLNLSDLRRSIGLVSQDVFLFHGTVAENIAYGTFDASDEAIINAAKVAEAHDF 476 Query: 464 ISSLPEGYDTPVREAGQRFSGGERQRIALARILLQNTPAVVLDEPTVGLDPRTERELLAT 523 I LP+GY+T V E GQ+ SGG+RQRIA+AR +L+N P ++LDE T +D TE + + Sbjct: 477 IMRLPQGYETIVGERGQKLSGGQRQRIAIARAVLKNPPILILDEATSAVDNETEAAIQRS 536 Query: 524 MFTAMADKTLIWVTHHLVGAEQMDEVIFMENGTVEMRGTH 563 + ++T I + H L + ME+G + +GTH Sbjct: 537 LEKITVNRTTIAIAHRLSTIRHSHCIYVMEHGQIVEQGTH 576 >all2676 [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Length = 989 Score = 155 bits (391), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 84/227 (37%), Positives = 132/227 (58%), Gaps = 15/227 (6%) Query: 345 IQLKNTGYRYASGEDWSIQDLNLDIPQGRKIAIIGRSGAGKSTLLKVIQGVIAPSVGSAV 404 ++ + +R+ + + +++LDIP G+ + ++G+SGAGKSTL K++ + P VG + Sbjct: 748 VKYDHITFRFTNSPTPQLDNISLDIPPGKFVGVVGQSGAGKSTLTKLLTRLYDPEVGRIL 807 Query: 405 INGIAASAYGEDIPKL--------IAVLNQSPHLFDTTVANNIRLGKPDASDEEVKQAGK 456 I+G DI K+ I ++ Q LFDTTV NI L P+A+ EE+ A K Sbjct: 808 IDGY-------DIHKVELYSLRRQIGMVLQDTLLFDTTVQENIALNNPEATPEEIINAAK 860 Query: 457 LAQLDDLISSLPEGYDTPVREAGQRFSGGERQRIALARILLQNTPAVVLDEPTVGLDPRT 516 +A + I SLP GY+T V E G SGG+RQRIA+AR +LQN +++DE T LD + Sbjct: 861 IAYAHEFIMSLPMGYNTRVGERGSALSGGQRQRIAIARTVLQNPRLLIMDEATSALDYNS 920 Query: 517 ERELLATMFTAMADKTLIWVTHHLVGAEQMDEVIFMENGTVEMRGTH 563 ER++ + A+ +T+ ++TH L D ++ ME G + +GTH Sbjct: 921 ERQVCQNLQQALEGRTVFFITHRLGTIRHADIILMMEQGRIAEQGTH 967 >PM0861 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 582 Score = 154 bits (390), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 80/224 (35%), Positives = 132/224 (58%), Gaps = 2/224 (0%) Query: 342 QVHIQLKNTGYRYASGEDWSIQDLNLDIPQGRKIAIIGRSGAGKSTLLKVIQGVIAPSVG 401 Q ++ KN + Y S ++ ++++L+ D+ +G+ +A++GRSG+GKST+ ++ G Sbjct: 339 QGYLSFKNVTFTYQSRDEPALRNLSFDVEKGKTVALVGRSGSGKSTIANLVTRFYDVDQG 398 Query: 402 SAVINGIAASAYG-EDIPKLIAVLNQSPHLFDTTVANNIRLGKPDA-SDEEVKQAGKLAQ 459 ++GI Y + K AV++Q HLF+ T+ANNI D S EE+ +A K A Sbjct: 399 EITLDGINIQDYRLSSLRKNCAVVSQQVHLFNDTIANNIAYAAKDKYSREEIIKAAKDAY 458 Query: 460 LDDLISSLPEGYDTPVREAGQRFSGGERQRIALARILLQNTPAVVLDEPTVGLDPRTERE 519 + I L G DT + E G SGG+RQR+A+AR LL+N+P ++LDE T LD +ER Sbjct: 459 AMEFIEKLEHGLDTVIGENGVNLSGGQRQRLAIARALLRNSPVLILDEATSALDTESERS 518 Query: 520 LLATMFTAMADKTLIWVTHHLVGAEQMDEVIFMENGTVEMRGTH 563 + + ++T+I + H L E DE++ +E+G ++ RG+H Sbjct: 519 IQLALEKLQKERTVIVIAHRLSTIENADEILVIEHGEIKERGSH 562 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.322 0.138 0.398 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 38,438,287 Number of extensions: 1626296 Number of successful extensions: 21268 Number of sequences better than 1.0e-05: 1909 Number of HSP's gapped: 19250 Number of HSP's successfully gapped: 2048 Length of query: 592 Length of database: 38,378,431 Length adjustment: 112 Effective length of query: 480 Effective length of database: 25,461,023 Effective search space: 12221291040 Effective search space used: 12221291040 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 119 (50.4 bits)