BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0044.0006.p
         (465 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

lin1658 [GEPR] COG0477 Permeases of the major facilitator superf...    65   2e-10
lin0519 [GEPR] COG0477 Permeases of the major facilitator superf...    65   3e-10
L132251 [GEPR] COG0477 Permeases of the major facilitator superf...    51   5e-06

>lin1658 [GEPR] COG0477 Permeases of the major facilitator superfamily
          Length = 489

 Score = 65.1 bits (157), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 47/164 (28%), Positives = 74/164 (45%), Gaps = 1/164 (0%)

Query: 20  TLPREGLLTFLFSVAVVLVIMNTAMFNLALPDVTETFGISASAASWIVTGYSIMFSIASI 79
           ++ R G+L  +   A V  I+N  + N+ALP + + FGI+AS   W+ TG+ ++  +   
Sbjct: 7   SVKRNGILIVMLMGAFV-TILNQTLMNVALPSIMKDFGITASQGQWLSTGFMLVNGVMIP 65

Query: 80  TYSRLSDFLPXXXXXXXXXXXXXXXXVAGFFSTNFIVLLIVRIVQASGAGAVMSLSLVLF 139
             + L +                     G F+T++ +L+  R+VQA GAG VM L  V+ 
Sbjct: 66  MTAFLIERFTTRQLYLFAMITFAIGTAIGGFATDYTMLIAGRMVQAIGAGIVMPLLTVVV 125

Query: 140 TRYVPLGRRGKAMATIMXXXXXXXXXXXXXXXXITQYFGWNWLF 183
               P+ RRG+AM  I                 I Q + W  LF
Sbjct: 126 LNLFPMERRGRAMGLIGLAMNFAPAIGPTLSGWIVQQYDWRNLF 169


>lin0519 [GEPR] COG0477 Permeases of the major facilitator superfamily
          Length = 471

 Score = 64.7 bits (156), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 81/383 (21%), Positives = 137/383 (35%), Gaps = 14/383 (3%)

Query: 45  FNLALPDVTETFGISASAASWIVTGYSIMFSIASITYSRLSDFLPXXXXXXXXXXXXXXX 104
            N+AL D+ + F IS++   W+ TGY +   I       L  +                 
Sbjct: 34  LNMALSDLIQVFDISSATVQWLTTGYLLTLGILVPISGLLLQWFTTRGLFFTAVSFSIAG 93

Query: 105 XVAGFFSTNFIVLLIVRIVQASGAGAVMSLSLVLFTRYVPLGRRGKAMATIMXXXXXXXX 164
            +    S  F +L+I R+VQA G   ++ L         P  +RG AM  I         
Sbjct: 94  TLIAALSPTFAMLMIGRVVQAVGTALLLPLMFNTILLIFPEHKRGSAMGMIGLVIMFAPA 153

Query: 165 XXXXXXXXITQYFGWNWLFAVTA--IIXXXXXXXXXXXXXXXXSRGSFDAXXXXXXXXX- 221
                   I +   WNW+F ++   +I                ++   D           
Sbjct: 154 VGPTISGLILENLTWNWIFWISLPFLIIALLFGMKFMQNVSVVTKPKIDILSIILSTLGF 213

Query: 222 --XXXXXXXXXXXXW------IALVAGIAAIFLFVSRIRTISDPFVMPALFKNRPYLVLS 273
                         W      ++++ G  A+ LFV R  T+  P +   +FK  P   L 
Sbjct: 214 GGVVFAFSSAGENGWGSATVLVSIIVGGIALGLFVWRQLTMEKPLMDLKVFK-YPMFTLG 272

Query: 274 LVGI-ASYLCSFATLFLLPQILVHRFGFTASHAGFVIFPGSLLAIFVSRSVGRIIDRFGN 332
           L+ +  S++   +T+ LLP  L +     A  AG V+ PG +L   +S   GR+ D +G 
Sbjct: 273 LILVFISFMMILSTMILLPLYLQNSLALAAFSAGLVLLPGGVLNGLMSPFTGRLFDAYGP 332

Query: 333 GG-ILRXXXXXXXXXXXXXXXXXGHSWIAVMFVYMIMSLAFTTLSSSVSNEISRVLPSSQ 391
              ++                  G S + ++ ++ ++ +  + +           LP   
Sbjct: 333 RALVIPGFIVAVIALFFLTRIEVGTSALTIIVLHSVLMIGISMVMMPAQTNGLNQLPPKL 392

Query: 392 IGSGMGLFQLLQFFSGAFGVAMA 414
              G  +   LQ  SGA G A+A
Sbjct: 393 YPDGTAIMNTLQQVSGAIGTAVA 415


>L132251 [GEPR] COG0477 Permeases of the major facilitator superfamily
          Length = 514

 Score = 50.8 bits (120), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 31/96 (32%), Positives = 50/96 (52%)

Query: 237 LVAGIAAIFLFVSRIRTISDPFVMPALFKNRPYLVLSLVGIASYLCSFATLFLLPQILVH 296
           +V G+  IFLF  R   + DPF+   +FK R + +++L    S +       +LP  L  
Sbjct: 257 IVGGLIIIFLFGLRQLKMDDPFLDIRVFKIRQFTLVTLALALSTMAMMGVEMMLPLYLQD 316

Query: 297 RFGFTASHAGFVIFPGSLLAIFVSRSVGRIIDRFGN 332
             G +A ++G V+ PGSL+   V+   G + DR G+
Sbjct: 317 VHGLSAFNSGLVLLPGSLMMAVVAPLAGGVYDRIGS 352


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.330    0.139    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 22,398,301
Number of extensions: 675481
Number of successful extensions: 2093
Number of sequences better than 1.0e-05: 18
Number of HSP's gapped: 2130
Number of HSP's successfully gapped: 22
Length of query: 465
Length of database: 38,378,431
Length adjustment: 110
Effective length of query: 355
Effective length of database: 25,691,691
Effective search space: 9120550305
Effective search space used: 9120550305
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 118 (50.1 bits)