BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0043.0023.p (255 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH3679 [T] COG4753 Response regulator containing CheY-like recei... 220 2e-57 SPy1556 [T] COG4753 Response regulator containing CheY-like rece... 107 2e-23 BH2728 [T] COG4753 Response regulator containing CheY-like recei... 95 1e-19 SPy1587 [T] COG4753 Response regulator containing CheY-like rece... 93 5e-19 BH2109 [T] COG4753 Response regulator containing CheY-like recei... 90 3e-18 >BH3679 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 257 Score = 220 bits (560), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 109/245 (44%), Positives = 156/245 (63%) Query: 1 VDDEPRTRQGIRQTLEVWAAGRYIVETAENGIDARERLLNGRVHLLITDVRMPEVSGLDL 60 VDDEPR+R+G+++TLE W+ V+TA + +A RL + L+ITD+RMPE+SGL L Sbjct: 9 VDDEPRSRRGLKRTLEAWSPKLLNVQTAASAKEAITRLNEETIDLIITDIRMPEMSGLHL 68 Query: 61 IRSLEGQVRKPVIIVISGYAEFDYVQQALRLGAVNYLLKPLDKEELXXXXXXXXXXXXXX 120 +++L+ Q KPV IVIS Y+EF+Y AL LG +YLLKP+ KE+L Sbjct: 69 VKALQEQNPKPVCIVISAYSEFEYAHTALELGVRHYLLKPVKKEKLIEAVESALQMKKEQ 128 Query: 121 XXXXXXXXXVDHKLLEIDPDTAGMGEPVKEALAYVEQHLHEQLTMAEVAGRIHLNASYFS 180 D K+ I+ + + + EAL Y++ HL +++ + +VA +HLN SY S Sbjct: 129 DRFGQVEKVWDEKIDAIEKERLSSSDSIHEALHYIDAHLDQKIGLKDVAKSVHLNPSYLS 188 Query: 181 VLFKEQTGVPFSEYLSRLRIQRAKELLLQTSLPIIEIGERVGYRTDKYFIKVFKSLEDMS 240 LFKE+T + FSEYL+R R+Q AK LL+ T PI +I E+ GY+T KYFIK+FK E M+ Sbjct: 189 ALFKEKTNMTFSEYLTRKRLQHAKHLLVSTDRPISDIAEKCGYQTAKYFIKIFKEHEGMT 248 Query: 241 PSRYR 245 P++YR Sbjct: 249 PTQYR 253 >SPy1556 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 246 Score = 107 bits (267), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 80/253 (31%), Positives = 133/253 (52%), Gaps = 26/253 (10%) Query: 1 VDDEPRTRQGIRQTLEVWAAGRYIVETAENGIDARERLLNGRVHLLITDVRMPEVSGLDL 60 V+DE RQGIR ++ V AENG A + +++TD+ MP+++G+ L Sbjct: 7 VEDEYLVRQGIRSLVDFSQFKIDRVNEAENGQLAWDLFQKEPYDIVLTDINMPKLNGIQL 66 Query: 61 IRSLEGQVRKPVIIVISGYAEFDYVQQALRLGAVNYLLKPLDKEELXXXXXXXXXXXXXX 120 ++ + + ++ ++GY +F+Y AL+LGA +YLLKP K ++ Sbjct: 67 AELIKQESPQTHLVFLTGYDDFNYALSALKLGADDYLLKPFSKADVEDMLGKL------- 119 Query: 121 XXXXXXXXXVDHKLLEIDPDTAGMGE----PVKE----ALAYVEQHLHEQLTMAEVAGRI 172 K LE+ T + E P KE A+A E+ LT+ +A ++ Sbjct: 120 -----------RKKLELSKKTETIQELVEQPQKEVSAIAMAIHERLADSDLTLKSLAQQL 168 Query: 173 HLNASYFSVLFKEQTGVPFSEYLSRLRIQRAKELLLQTSLPIIEIGERVGYRTDKYFIKV 232 + +Y SVL K++ G+PF +YL + R+++AK LLL ++L I EI E+VG+ YF + Sbjct: 169 GFSPNYLSVLIKKELGMPFQDYLVQERLKKAKLLLLTSNLKIYEIAEQVGFEDMNYFSQR 228 Query: 233 FKSLEDMSPSRYR 245 FK L ++PS+Y+ Sbjct: 229 FKQLVGVTPSQYK 241 >BH2728 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 510 Score = 94.7 bits (234), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 44/100 (44%), Positives = 65/100 (65%) Query: 148 VKEALAYVEQHLHEQLTMAEVAGRIHLNASYFSVLFKEQTGVPFSEYLSRLRIQRAKELL 207 +++ LAY+E+H E L+++++A H N SY S F++ FSEYL+++RI++AKE L Sbjct: 402 IQKMLAYIEEHHSEPLSLSQLANYFHFNPSYLSAYFRQHHDEGFSEYLNKVRIRKAKEWL 461 Query: 208 LQTSLPIIEIGERVGYRTDKYFIKVFKSLEDMSPSRYRHQ 247 +++PI EI VGY YF KVFK M PSRYR + Sbjct: 462 KSSTIPISEIYALVGYSDHSYFCKVFKKRTGMPPSRYRRE 501 Score = 73.6 bits (179), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 38/100 (38%), Positives = 57/100 (57%) Query: 1 VDDEPRTRQGIRQTLEVWAAGRYIVETAENGIDARERLLNGRVHLLITDVRMPEVSGLDL 60 VDDE RQGI + G IV A NG DA E + H+++TD+ MP + G+DL Sbjct: 7 VDDEKLIRQGIINFFDWEKEGFQIVGEAANGKDALELISKNEPHIVMTDIVMPVMDGIDL 66 Query: 61 IRSLEGQVRKPVIIVISGYAEFDYVQQALRLGAVNYLLKP 100 ++ ++ + IIV+S + EF+YV+ G +Y+LKP Sbjct: 67 VKRVKRDFPEVEIIVLSSFEEFEYVRSTFHSGVADYILKP 106 >SPy1587 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 494 Score = 92.8 bits (229), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 43/108 (39%), Positives = 66/108 (61%) Query: 148 VKEALAYVEQHLHEQLTMAEVAGRIHLNASYFSVLFKEQTGVPFSEYLSRLRIQRAKELL 207 V E + + + H++LT+ +A R+H+N Y FK +T F++YL+ +RIQ+A++LL Sbjct: 383 VSETIDCIRKEYHQELTLKAIADRLHVNGVYLGQCFKNETERSFTQYLNHVRIQKAQQLL 442 Query: 208 LQTSLPIIEIGERVGYRTDKYFIKVFKSLEDMSPSRYRHQMKDGRGEI 255 L T+ I EI GY T+ YFIK+FK L +SP +R + KD I Sbjct: 443 LYTNQSINEIAYETGYNTNHYFIKMFKKLNGLSPKEFRDRYKDNYQAI 490 Score = 80.1 bits (196), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 44/106 (41%), Positives = 65/106 (61%) Query: 1 VDDEPRTRQGIRQTLEVWAAGRYIVETAENGIDARERLLNGRVHLLITDVRMPEVSGLDL 60 VDDE QG+ ++ A G +V+TA +G +A L V ++I+DV MP ++GLDL Sbjct: 7 VDDEYMILQGLTMIIDWQALGFEVVQTARSGKEALAYLTQYPVDVMISDVTMPGMTGLDL 66 Query: 61 IRSLEGQVRKPVIIVISGYAEFDYVQQALRLGAVNYLLKPLDKEEL 106 I + + + +++SGY EF YVQ+A+ L YLLKP+DK EL Sbjct: 67 IEAAKTYHPQLQTLILSGYQEFSYVQKAMELETKGYLLKPVDKAEL 112 >BH2109 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 525 Score = 90.1 bits (222), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 38/106 (35%), Positives = 64/106 (60%) Query: 143 GMGEPVKEALAYVEQHLHEQLTMAEVAGRIHLNASYFSVLFKEQTGVPFSEYLSRLRIQR 202 M + + Y+E H HE +++ +A ++N Y LFK+ GV F EYL +LR+ Sbjct: 418 NMKSDIYKVKTYIENHYHENISLKSIASLFYMNPVYMGQLFKKTFGVYFKEYLLKLRMNE 477 Query: 203 AKELLLQTSLPIIEIGERVGYRTDKYFIKVFKSLEDMSPSRYRHQM 248 AK+LL QT + + E+ ERVG+ + YF+ F+ + M+P+ YR+++ Sbjct: 478 AKKLLRQTDMRVYEVAERVGFGSTDYFVTQFEKINKMTPTEYRNKL 523 Score = 82.8 bits (203), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 42/106 (39%), Positives = 65/106 (61%), Gaps = 1/106 (0%) Query: 2 DDEPRTRQGIRQTLEVWAAGRYIVETAENGIDARERLLNGRVHLLITDVRMPEVSGLDLI 61 DDE R G++ +E G + A+NG DA + + + L+ITD+RMP GL LI Sbjct: 8 DDEFFVRHGLKSLIEWEKCGYEVAAEADNGEDAFKLVQEIKPDLVITDIRMPVFDGLQLI 67 Query: 62 RSLEGQVR-KPVIIVISGYAEFDYVQQALRLGAVNYLLKPLDKEEL 106 + + + I+ISGY +F Y Q+A+R GAV+++LKP+D++EL Sbjct: 68 QKVNETLSFNTKFIIISGYNDFSYAQKAVRFGAVDFVLKPIDQDEL 113 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.320 0.139 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 17,315,361 Number of extensions: 664568 Number of successful extensions: 3582 Number of sequences better than 1.0e-05: 983 Number of HSP's gapped: 3673 Number of HSP's successfully gapped: 993 Length of query: 255 Length of database: 38,378,431 Length adjustment: 104 Effective length of query: 151 Effective length of database: 26,383,695 Effective search space: 3983937945 Effective search space used: 3983937945 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 114 (48.5 bits)