BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0042.0001.p (319 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value lin2535 [K] COG2378 Predicted transcriptional regulator 96 6e-20 lin0464 [K] COG2378 Predicted transcriptional regulator 96 6e-20 BH1889 [K] COG2378 Predicted transcriptional regulator 76 7e-14 mll4985 [K] COG2378 Predicted transcriptional regulator 72 1e-12 lin0395 [K] COG2378 Predicted transcriptional regulator 65 2e-10 >lin2535 [K] COG2378 Predicted transcriptional regulator Length = 298 Score = 96.3 bits (238), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 85/322 (26%), Positives = 140/322 (43%), Gaps = 38/322 (11%) Query: 3 KADYMLSILWILQQHKRTAAELAGELELSVRSVYRYIDALCASGVPVIADAGPGGGYSLP 62 K + +L+IL ++ + K A+ELA + E+S R++YR +D L +G PV+A G GG+++ Sbjct: 2 KLERILAILVMILERKVLASELAEKFEVSTRTIYRDMDTLLYAGFPVVALPGKNGGFTML 61 Query: 63 EHFSAAPLFFDAGERRALVQA----SAFARGSGYPYEQALDGAIAKL---KRYSNAEQLS 115 + + A F E+R L++A S F ++ L I L K SN Sbjct: 62 DTYKLATFTFSEEEKRILLEALEARSEFMLNDS---QETLREKITLLQTEKPTSNYIFFD 118 Query: 116 QMERHESGLETLHSXXXXXXXXXXXXXXCTADSLTLEMEYRKGNGGFPSSRCIDPYGLVL 175 +H +E L++ Y +G ++R I P L L Sbjct: 119 SATQHRKQIEA------EVKRKIAYIQKAFTMKKQLDITYIAMDGT-ETNREISPQKLNL 171 Query: 176 WKGQWYLTGFCHQRQEVRSFRVDRIAGLRRTGAGFIRPASFSAREFLLQSLLPGQNNPAK 235 G WYL +CH+R +R F++ RI L+ T ++ + A+ Sbjct: 172 MDGSWYLEAYCHKRAAIRHFKLTRITSLKETSKTSMK--------------IEEDQKQAE 217 Query: 236 LT-AVVISAAEDVLNDLCSHWLFGHTLEQRSENTARFLLDEATLYSYTPYFLLPYGKALT 294 +T +V+ ++ L L ++L + RF D + P FLL +G A+ Sbjct: 218 VTEKIVLEFPKNQLGKLLDYFLLEEMQMELDLVRVRFQYDPER--NIIP-FLLMFGSAVK 274 Query: 295 IREPAALKKKLAEVTAELTAYY 316 I EPA+L+K E AE+ Y Sbjct: 275 ILEPASLQK---EYKAEVEKLY 293 >lin0464 [K] COG2378 Predicted transcriptional regulator Length = 310 Score = 96.3 bits (238), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 82/325 (25%), Positives = 143/325 (44%), Gaps = 29/325 (8%) Query: 3 KADYMLSILWILQQHKRTAA-ELAGELELSVRSVYRYIDALCASGVPVIADAGPGGGYSL 61 K D ++SI+ IL +R +A ELA E+S+R++YR IDA+ +GVP+ + G GGG+ + Sbjct: 2 KVDRLMSIVLILLDKERISAQELADRFEVSLRTIYRDIDAIDLAGVPIRSTPGVGGGFEI 61 Query: 62 PEHFSAAPLFFDAGERRALVQA----SAFARGSGYPYEQALDGAIAKLKRYSNAEQLSQM 117 + F + A++ S RG L A+AK+K + A++ ++ Sbjct: 62 MPDYKMDSKVFSTADLSAILMGLSSLSNMVRGD------ELINALAKIKSFIPADRAKEI 115 Query: 118 ERHESGLETLHSX---XXXXXXXXXXXXXCTADSLTLEMEYRKGNGGFPSSRCIDPYGLV 174 E + + S ++ L EY G + R ++PY LV Sbjct: 116 ELKANQIYIDLSQWTGNNNIQPHVEIIKVALQENKLLTFEYIAHQGN-KTVRIVEPYQLV 174 Query: 175 LWKGQWYLTGFCHQRQEVRSFRVDRIAGLRRTGAGFIRPASFSAREFLLQSLLPGQNNPA 234 + WYL G+C R + R FR+ R++GL+ I +F+ R+F L Sbjct: 175 MKSSHWYLYGYCQNRNDFRLFRLSRMSGLQ------ILEDTFTLRDFQKPQLEMEDIVAI 228 Query: 235 KLTAVVISAAEDVLN---DLCSHWLFGHTLEQRSENTARFLLDEATLYSYTPYFLLPYGK 291 + I + +++ D CS+ F E+ + F+ +E Y Y LL +G Sbjct: 229 MQIEIKIRIHQSIIDRVLDYCSYENFYPDGEEHYIVSFPFIENE---YHYD--ILLSFGD 283 Query: 292 ALTIREPAALKKKLAEVTAELTAYY 316 EP +++K+ ++ + Y Sbjct: 284 KCECLEPLHVREKMKRRIYDIVSIY 308 >BH1889 [K] COG2378 Predicted transcriptional regulator Length = 325 Score = 75.9 bits (185), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 80/328 (24%), Positives = 134/328 (40%), Gaps = 25/328 (7%) Query: 1 MSKADYMLSILWILQQHKR-TAAELAGELELSVRSVYRYIDALCASGVPVIADAGPGGGY 59 MSKA ++ ++ ++ + +R T ELA E +S R++ R + L GVP+ ++ GP GGY Sbjct: 1 MSKAKRLMELMMVINRKRRFTVKELAEEFSVSSRTILRDLQELSELGVPLYSEVGPHGGY 60 Query: 60 SLPEHFSAAPLFFDAGERRAL-VQASAFARGSGYPYEQALDGAIAKLKRY---SNAEQLS 115 + P+ F E A+ A S P++ K Y E++ Sbjct: 61 EVLNERVLPPIAFTEEEAVAIFFTVHALRHFSALPFQAESSSVNHKFYSYMPEDVKERID 120 Query: 116 QMERHESGLETLHSXXXXXXXXXXXXXXCTADSLTLEMEYRKGNGGFPSSRCIDPYGLVL 175 Q+ ++ ET + +++E E + + R I P G+ Sbjct: 121 QL-KNRFDFETPMRPLATPYLPTLLDAAIKQNVVSIEYETSQEK----TKREIQPIGVYA 175 Query: 176 WKGQWYLTGFCHQRQEVRSFRVDRIAGLRRTGAGFIRPASFSAREFLL---QSLLPGQNN 232 G WY +C R+++R FR DRI + P +F R L QS + + N Sbjct: 176 RDGFWYCPSYCFLREDMRLFRCDRITYVTEQTTN--NPLNF--RHVHLGNWQSYMKQERN 231 Query: 233 PAKLTAVVISAAEDVLNDLCSHWLFGHTLEQRSENTARFLLDEATLYSYTPYF---LLPY 289 L V + + V + WL H L R + + L+ S PYF + + Sbjct: 232 --VLDFYVELSQDGVQRCVAEQWLKPH-LHIRQDGSG--WLEGPFPESEVPYFSYYFIGF 286 Query: 290 GKALTIREPAALKKKLAEVTAELTAYYN 317 G T+++P L + + EL + YN Sbjct: 287 GHDATVKQPVQLVTLIKKSLRELLSKYN 314 >mll4985 [K] COG2378 Predicted transcriptional regulator Length = 234 Score = 72.0 bits (175), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 66/216 (30%), Positives = 93/216 (43%), Gaps = 13/216 (6%) Query: 1 MSKADYMLSILWILQQHKR--TAAELAGELELSVRSVYRYIDALCASGVPVIADAGPGGG 58 M KA + I+ IL+ ++ TAA +A LE+++RS+YR I AL A VP+ + G G G Sbjct: 4 MRKASRLFEIIQILRLARQPVTAAMIAERLEVTIRSIYRDIAALQAMRVPI--EGGRGIG 61 Query: 59 YSLPEHFSAAPLFFDAGERRALVQASAFARGSGYPYEQALDGAIAKLKRYSNAEQLSQME 118 Y L F PL F E A+V + A +G + L A AK A + Sbjct: 62 YILRPGFDLPPLMFSIEEMEAIVLSLALLERTG---DDELKQA-AKRVSSKIAGAVPPPL 117 Query: 119 RHESGLETLH----SXXXXXXXXXXXXXXCTADSLTLEMEYRKGNGGFPSSRCIDPYGLV 174 R LH + D L++ YR G + R I P L+ Sbjct: 118 RQTFDANALHAWGFAAPSAGTIDLALVRRAIRDEEKLDLSYRD-EAGRTTQRIIRPIALI 176 Query: 175 LWKGQWYLTGFCHQRQEVRSFRVDRIAGLRRTGAGF 210 + +C RQ +R+FR DRI G + TG F Sbjct: 177 YYAEAVNTVAWCELRQAIRNFRSDRIEGCQPTGLHF 212 >lin0395 [K] COG2378 Predicted transcriptional regulator Length = 306 Score = 64.7 bits (156), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 73/319 (22%), Positives = 122/319 (38%), Gaps = 35/319 (10%) Query: 10 ILWILQQHKRTAAELAGELELSVRSVYRYIDALCASGVPVIADAGPGGGYSLPEHFSAAP 69 I+ +LQ+ +A+E+A E+S R+++R ID L + +P+ AG GG + + Sbjct: 10 IMLLLQRELVSASEMATMFEVSKRTIFRDIDTLSMANIPIYTIAGTKGGIGIMPTYKVDK 69 Query: 70 LFFDAGERRALVQASAFARGSGYPYEQALDGAIAKLKRYSNAEQLSQMERHESGLETLHS 129 A + A++ S EQ L A K +++ M H S Sbjct: 70 KLLTADDLTAII-------ASLDGMEQLLSSAETK----KTLQKMKNMLEHSSEPPKSSI 118 Query: 130 XXXXXXXXXXXXXXCTADSLTL--------EMEY--RKGNGGFPSSRCIDPYGLVLWKGQ 179 +SL L E+ Y R GN + R +PY L+ Sbjct: 119 SLDFSNLSMKKELNAKVESLYLAIKKHQLVELSYIDRTGNQ---TVRKTEPYHLLFRNRS 175 Query: 180 WYLTGFCHQRQEVRSFRVDRIAGLRRTGAGFIRPASFSAREFLLQSLLPGQNNPAKLTAV 239 WYL G+ +R + R+F++ RI L+ +F AR F+++ + P L Sbjct: 176 WYLQGYSLERSDFRTFKMSRIVELKTL------EETFEARPFVVKPFSMTGDRPTFLMHE 229 Query: 240 VISAAEDVLNDLCSHWLFGHTLEQRSENTARFLLDEATLYSYTP--YFLLPYGKALTIRE 297 V + + + + Q E FL+ + TL + FLL G +TI+ Sbjct: 230 VTLIVDKIAREQIVERFDPVAISQHDEE--HFLV-KVTLPDHEAGYRFLLQLGTHVTIQN 286 Query: 298 PAALKKKLAEVTAELTAYY 316 + AE+ Y Sbjct: 287 RDDFYDSFVDYLAEIQGKY 305 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.320 0.134 0.400 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 22,713,123 Number of extensions: 825255 Number of successful extensions: 1435 Number of sequences better than 1.0e-05: 15 Number of HSP's gapped: 1423 Number of HSP's successfully gapped: 16 Length of query: 319 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 213 Effective length of database: 26,153,027 Effective search space: 5570594751 Effective search space used: 5570594751 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 116 (49.3 bits)